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The map label for this gene is ptsG

Identifier: 16078453

GI number: 16078453

Start: 1457187

End: 1459286

Strand: Direct

Name: ptsG

Synonym: BSU13890

Alternate gene names: 16078453

Gene position: 1457187-1459286 (Clockwise)

Preceding gene: 255767321

Following gene: 16078454

Centisome position: 34.57

GC content: 45.38

Gene sequence:

>2100_bases
ATGTTTAAAGCATTATTCGGCGTTCTTCAAAAAATTGGGCGTGCGCTTATGCTTCCAGTTGCGATCCTTCCGGCTGCGGG
TATTTTGCTTGCGATCGGGAATGCGATGCAAAATAAGGACATGATTCAGGTCCTGCATTTCTTGAGCAATGACAATGTTC
AGCTTGTAGCAGGTGTGATGGAAAGTGCTGGGCAGATTGTTTTCGATAACCTTCCGCTTCTTTTCGCAGTAGGTGTAGCC
ATCGGGCTTGCCAATGGTGATGGAGTTGCAGGGATTGCAGCAATTATCGGTTATCTTGTAATGAATGTATCCATGAGTGC
GGTTCTTCTTGCAAACGGAACCATTCCTTCGGATTCAGTTGAAAGAGCCAAGTTCTTTACGGAAAACCATCCTGCATATG
TAAACATGCTTGGTATACCTACCTTGGCGACAGGGGTGTTCGGCGGTATTATCGTCGGTGTGTTAGCTGCATTATTGTTT
AACAGATTTTACACAATTGAACTGCCGCAATACCTTGGTTTCTTTGCGGGTAAACGTTTCGTTCCAATTGTTACGTCAAT
TTCTGCACTGATTCTGGGTCTTATTATGTTAGTGATCTGGCCTCCAATCCAGCATGGATTGAATGCCTTTTCAACAGGAT
TAGTGGAAGCGAATCCAACCCTTGCTGCATTTATCTTCGGGGTGATTGAACGTTCGCTTATCCCATTCGGATTGCACCAT
ATTTTCTATTCACCGTTCTGGTATGAATTCTTCAGCTATAAGAGTGCAGCAGGAGAAATCATCCGCGGGGATCAGCGTAT
CTTTATGGCGCAGATTAAAGACGGCGTACAGTTAACGGCAGGTACGTTCATGACAGGTAAATATCCATTTATGATGTTCG
GTCTGCCTGCTGCGGCGCTTGCCATTTATCATGAAGCAAAACCGCAAAACAAAAAACTCGTTGCAGGTATTATGGGTTCA
GCGGCCTTGACATCTTTCTTAACGGGGATCACAGAGCCATTGGAATTTTCTTTCTTATTCGTTGCTCCAGTCCTGTTTGC
GATTCACTGTTTGTTTGCGGGACTTTCATTCATGGTCATGCAGCTGTTGAATGTTAAGATTGGTATGACATTCTCCGGCG
GTTTAATTGACTACTTCCTATTCGGTATTTTACCAAACCGGACGGCATGGTGGCTTGTCATCCCTGTCGGCTTAGGGTTA
GCGGTCATTTACTACTTTGGATTCCGATTTGCCATCCGCAAATTTAATCTGAAAACACCTGGACGCGAGGATGCTGCGGA
AGAAACAGCAGCACCTGGGAAAACAGGTGAAGCAGGAGATCTTCCTTATGAGATTCTGCAGGCAATGGGTGACCAGGAAA
ACATCAAACACCTTGATGCTTGTATCACTCGTCTGCGTGTGACTGTAAACGATCAGAAAAAGGTTGATAAAGACCGTCTG
AAACAGCTTGGCGCTTCCGGAGTGCTGGAAGTCGGCAACAACATTCAGGCTATTTTCGGACCGCGTTCTGACGGGTTAAA
AACACAAATGCAAGACATTATTGCGGGACGCAAGCCTAGACCTGAGCCGAAAACATCTGCTCAAGAGGAAGTAGGCCAGC
AGGTTGAGGAAGTGATTGCAGAACCGCTGCAAAATGAAATCGGCGAGGAAGTTTTCGTTTCTCCGATTACCGGGGAAATT
CACCCAATTACGGATGTTCCTGACCAAGTCTTCTCAGGGAAAATGATGGGTGACGGTTTTGCGATTCTCCCTTCTGAAGG
AATTGTCGTATCACCGGTTCGCGGAAAAATTCTCAATGTGTTCCCGACAAAACATGCGATCGGCCTGCAATCCGACGGCG
GAAGAGAAATTTTAATCCACTTTGGTATTGATACCGTCAGCCTGAAGGGCGAAGGATTTACGTCTTTCGTATCAGAAGGA
GACCGCGTTGAGCCTGGACAAAAACTTCTTGAAGTTGATCTGGATGCAGTCAAACCGAATGTACCATCTCTCATGACACC
GATTGTATTTACAAACCTTGCTGAAGGAGAAACAGTCAGCATTAAAGCAAGCGGTTCAGTCAACAGAGAACAAGAAGATA
TTGTGAAGATTGAAAAATAA

Upstream 100 bases:

>100_bases
GCAAATGTAAACGGTTAAACTGGAAGACTTACGCCTGTGAATTCGTTGTCATGATTTTTAGCTGTAAGGTCAGACTAGTA
AAAAGAGGAGGTCAATTCTT

Downstream 100 bases:

>100_bases
GGGTGTTAGTACGCCGTGCTTGTCAGATGACAAGTACGGTTGTATGATATAATATTGTGAAGTAATAAAGCTTTAAGTTA
AAAGGAGAATGATAAAAATG

Product: phosphotransferase system (PTS) glucose-specific enzyme IICBA component

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component

Number of amino acids: Translated: 699; Mature: 699

Protein sequence:

>699_residues
MFKALFGVLQKIGRALMLPVAILPAAGILLAIGNAMQNKDMIQVLHFLSNDNVQLVAGVMESAGQIVFDNLPLLFAVGVA
IGLANGDGVAGIAAIIGYLVMNVSMSAVLLANGTIPSDSVERAKFFTENHPAYVNMLGIPTLATGVFGGIIVGVLAALLF
NRFYTIELPQYLGFFAGKRFVPIVTSISALILGLIMLVIWPPIQHGLNAFSTGLVEANPTLAAFIFGVIERSLIPFGLHH
IFYSPFWYEFFSYKSAAGEIIRGDQRIFMAQIKDGVQLTAGTFMTGKYPFMMFGLPAAALAIYHEAKPQNKKLVAGIMGS
AALTSFLTGITEPLEFSFLFVAPVLFAIHCLFAGLSFMVMQLLNVKIGMTFSGGLIDYFLFGILPNRTAWWLVIPVGLGL
AVIYYFGFRFAIRKFNLKTPGREDAAEETAAPGKTGEAGDLPYEILQAMGDQENIKHLDACITRLRVTVNDQKKVDKDRL
KQLGASGVLEVGNNIQAIFGPRSDGLKTQMQDIIAGRKPRPEPKTSAQEEVGQQVEEVIAEPLQNEIGEEVFVSPITGEI
HPITDVPDQVFSGKMMGDGFAILPSEGIVVSPVRGKILNVFPTKHAIGLQSDGGREILIHFGIDTVSLKGEGFTSFVSEG
DRVEPGQKLLEVDLDAVKPNVPSLMTPIVFTNLAEGETVSIKASGSVNREQEDIVKIEK

Sequences:

>Translated_699_residues
MFKALFGVLQKIGRALMLPVAILPAAGILLAIGNAMQNKDMIQVLHFLSNDNVQLVAGVMESAGQIVFDNLPLLFAVGVA
IGLANGDGVAGIAAIIGYLVMNVSMSAVLLANGTIPSDSVERAKFFTENHPAYVNMLGIPTLATGVFGGIIVGVLAALLF
NRFYTIELPQYLGFFAGKRFVPIVTSISALILGLIMLVIWPPIQHGLNAFSTGLVEANPTLAAFIFGVIERSLIPFGLHH
IFYSPFWYEFFSYKSAAGEIIRGDQRIFMAQIKDGVQLTAGTFMTGKYPFMMFGLPAAALAIYHEAKPQNKKLVAGIMGS
AALTSFLTGITEPLEFSFLFVAPVLFAIHCLFAGLSFMVMQLLNVKIGMTFSGGLIDYFLFGILPNRTAWWLVIPVGLGL
AVIYYFGFRFAIRKFNLKTPGREDAAEETAAPGKTGEAGDLPYEILQAMGDQENIKHLDACITRLRVTVNDQKKVDKDRL
KQLGASGVLEVGNNIQAIFGPRSDGLKTQMQDIIAGRKPRPEPKTSAQEEVGQQVEEVIAEPLQNEIGEEVFVSPITGEI
HPITDVPDQVFSGKMMGDGFAILPSEGIVVSPVRGKILNVFPTKHAIGLQSDGGREILIHFGIDTVSLKGEGFTSFVSEG
DRVEPGQKLLEVDLDAVKPNVPSLMTPIVFTNLAEGETVSIKASGSVNREQEDIVKIEK
>Mature_699_residues
MFKALFGVLQKIGRALMLPVAILPAAGILLAIGNAMQNKDMIQVLHFLSNDNVQLVAGVMESAGQIVFDNLPLLFAVGVA
IGLANGDGVAGIAAIIGYLVMNVSMSAVLLANGTIPSDSVERAKFFTENHPAYVNMLGIPTLATGVFGGIIVGVLAALLF
NRFYTIELPQYLGFFAGKRFVPIVTSISALILGLIMLVIWPPIQHGLNAFSTGLVEANPTLAAFIFGVIERSLIPFGLHH
IFYSPFWYEFFSYKSAAGEIIRGDQRIFMAQIKDGVQLTAGTFMTGKYPFMMFGLPAAALAIYHEAKPQNKKLVAGIMGS
AALTSFLTGITEPLEFSFLFVAPVLFAIHCLFAGLSFMVMQLLNVKIGMTFSGGLIDYFLFGILPNRTAWWLVIPVGLGL
AVIYYFGFRFAIRKFNLKTPGREDAAEETAAPGKTGEAGDLPYEILQAMGDQENIKHLDACITRLRVTVNDQKKVDKDRL
KQLGASGVLEVGNNIQAIFGPRSDGLKTQMQDIIAGRKPRPEPKTSAQEEVGQQVEEVIAEPLQNEIGEEVFVSPITGEI
HPITDVPDQVFSGKMMGDGFAILPSEGIVVSPVRGKILNVFPTKHAIGLQSDGGREILIHFGIDTVSLKGEGFTSFVSEG
DRVEPGQKLLEVDLDAVKPNVPSLMTPIVFTNLAEGETVSIKASGSVNREQEDIVKIEK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain

Homologues:

Organism=Escherichia coli, GI1787343, Length=514, Percent_Identity=47.2762645914397, Blast_Score=441, Evalue=1e-125,
Organism=Escherichia coli, GI1786894, Length=702, Percent_Identity=38.8888888888889, Blast_Score=428, Evalue=1e-121,
Organism=Escherichia coli, GI1787908, Length=522, Percent_Identity=37.7394636015326, Blast_Score=334, Evalue=1e-92,
Organism=Escherichia coli, GI1788757, Length=148, Percent_Identity=44.5945945945946, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI1790159, Length=160, Percent_Identity=43.75, Blast_Score=122, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PTG3C_BACSU (P20166)

Other databases:

- EMBL:   Z11744
- EMBL:   AL009126
- EMBL:   X12832
- EMBL:   M60344
- PIR:   S25083
- RefSeq:   NP_389272.1
- PDB:   1AX3
- PDB:   1GPR
- PDBsum:   1AX3
- PDBsum:   1GPR
- ProteinModelPortal:   P20166
- EnsemblBacteria:   EBBACT00000000820
- GeneID:   939255
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU13890
- NMPDR:   fig|224308.1.peg.1391
- GenoList:   BSU13890
- GeneTree:   EBGT00050000000032
- HOGENOM:   HBG571563
- OMA:   CIPAIAL
- PhylomeDB:   P20166
- ProtClustDB:   CLSK872840
- BioCyc:   BSUB:BSU13890-MONOMER
- BRENDA:   2.7.1.69
- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299
- Gene3D:   G3DSA:3.30.1360.60
- TIGRFAMs:   TIGR00826
- TIGRFAMs:   TIGR00830
- TIGRFAMs:   TIGR00852
- TIGRFAMs:   TIGR02002

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC; SSF51261 Dup_hybrid_motif; SSF55604 PTS_EIIB

EC number: =2.7.1.69

Molecular weight: Translated: 75526; Mature: 75526

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS51093 PTS_EIIA_TYPE_1; PS00371 PTS_EIIA_TYPE_1_HIS; PS51098 PTS_EIIB_TYPE_1; PS01035 PTS_EIIB_TYPE_1_CYS; PS51103 PTS_EIIC_TYPE_1

Important sites: ACT_SITE 461-461 ACT_SITE 620-620

Signals:

None

Transmembrane regions:

HASH(0xe5d2220)-; HASH(0xec2e118)-; HASH(0xe62f124)-; HASH(0xec53ebc)-; HASH(0xed784f0)-; HASH(0xe226a98)-; HASH(0xe3bcf88)-; HASH(0xe19db2c)-; HASH(0xe615ae8)-; HASH(0xd67c418)-; HASH(0xe32ec48)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKALFGVLQKIGRALMLPVAILPAAGILLAIGNAMQNKDMIQVLHFLSNDNVQLVAGVM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEHHHHH
ESAGQIVFDNLPLLFAVGVAIGLANGDGVAGIAAIIGYLVMNVSMSAVLLANGTIPSDSV
HHCCCEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCHHEEEEECCCCCCCHH
ERAKFFTENHPAYVNMLGIPTLATGVFGGIIVGVLAALLFNRFYTIELPQYLGFFAGKRF
HHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHCCCH
VPIVTSISALILGLIMLVIWPPIQHGLNAFSTGLVEANPTLAAFIFGVIERSLIPFGLHH
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IFYSPFWYEFFSYKSAAGEIIRGDQRIFMAQIKDGVQLTAGTFMTGKYPFMMFGLPAAAL
HHHCHHHHHHHHHHHHHHHHHCCCHHEEHHHHCCCCEEEECEEECCCCCHHHHCHHHHHH
AIYHEAKPQNKKLVAGIMGSAALTSFLTGITEPLEFSFLFVAPVLFAIHCLFAGLSFMVM
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLLNVKIGMTFSGGLIDYFLFGILPNRTAWWLVIPVGLGLAVIYYFGFRFAIRKFNLKTP
HHHCCCCCEEECCHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCC
GREDAAEETAAPGKTGEAGDLPYEILQAMGDQENIKHLDACITRLRVTVNDQKKVDKDRL
CCCCHHHHHCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHEEEECCHHHCCHHHH
KQLGASGVLEVGNNIQAIFGPRSDGLKTQMQDIIAGRKPRPEPKTSAQEEVGQQVEEVIA
HHCCCCCHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
EPLQNEIGEEVFVSPITGEIHPITDVPDQVFSGKMMGDGFAILPSEGIVVSPVRGKILNV
HHHHHHCCCCEEEECCCCCCCCCCCCCHHHHCCCCCCCCEEEECCCCEEEECCCCCEEEE
FPTKHAIGLQSDGGREILIHFGIDTVSLKGEGFTSFVSEGDRVEPGQKLLEVDLDAVKPN
CCCCCEECCCCCCCCEEEEEECCEEEEECCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCC
VPSLMTPIVFTNLAEGETVSIKASGSVNREQEDIVKIEK
CCHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHCCCH
>Mature Secondary Structure
MFKALFGVLQKIGRALMLPVAILPAAGILLAIGNAMQNKDMIQVLHFLSNDNVQLVAGVM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEHHHHH
ESAGQIVFDNLPLLFAVGVAIGLANGDGVAGIAAIIGYLVMNVSMSAVLLANGTIPSDSV
HHCCCEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCHHEEEEECCCCCCCHH
ERAKFFTENHPAYVNMLGIPTLATGVFGGIIVGVLAALLFNRFYTIELPQYLGFFAGKRF
HHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHCCCH
VPIVTSISALILGLIMLVIWPPIQHGLNAFSTGLVEANPTLAAFIFGVIERSLIPFGLHH
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IFYSPFWYEFFSYKSAAGEIIRGDQRIFMAQIKDGVQLTAGTFMTGKYPFMMFGLPAAAL
HHHCHHHHHHHHHHHHHHHHHCCCHHEEHHHHCCCCEEEECEEECCCCCHHHHCHHHHHH
AIYHEAKPQNKKLVAGIMGSAALTSFLTGITEPLEFSFLFVAPVLFAIHCLFAGLSFMVM
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLLNVKIGMTFSGGLIDYFLFGILPNRTAWWLVIPVGLGLAVIYYFGFRFAIRKFNLKTP
HHHCCCCCEEECCHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCC
GREDAAEETAAPGKTGEAGDLPYEILQAMGDQENIKHLDACITRLRVTVNDQKKVDKDRL
CCCCHHHHHCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHEEEECCHHHCCHHHH
KQLGASGVLEVGNNIQAIFGPRSDGLKTQMQDIIAGRKPRPEPKTSAQEEVGQQVEEVIA
HHCCCCCHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
EPLQNEIGEEVFVSPITGEIHPITDVPDQVFSGKMMGDGFAILPSEGIVVSPVRGKILNV
HHHHHHCCCCEEEECCCCCCCCCCCCCHHHHCCCCCCCCEEEECCCCEEEECCCCCEEEE
FPTKHAIGLQSDGGREILIHFGIDTVSLKGEGFTSFVSEGDRVEPGQKLLEVDLDAVKPN
CCCCCEECCCCCCCCEEEEEECCEEEEECCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCC
VPSLMTPIVFTNLAEGETVSIKASGSVNREQEDIVKIEK
CCHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1508157; 9384377; 2497294; 2120236; 1911744; 1906345; 9593197