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The map label for this gene is thiX

Identifier: 16078386

GI number: 16078386

Start: 1388070

End: 1388834

Strand: Reverse

Name: thiX

Synonym: BSU13210

Alternate gene names: 16078386

Gene position: 1388834-1388070 (Counterclockwise)

Preceding gene: 255767312

Following gene: 16078384

Centisome position: 32.95

GC content: 46.27

Gene sequence:

>765_bases
ATGAAGCAACCGTTACATCTCATTAATCCGACTGTGAAAGCGGCGGCGGTTTTTTGTTGTGTCGTCATGCTGTCGTTTAT
TTACAACCCTTACACTCCGGCATGTTTTTATATCATCATCGTTGCGGGCGTTTTACTGGCGGCCGGAATCCCATTGAAAA
AATGGTTGTTGTTTACGATTCCGTTTTTGATTTTAGCATTCGGATGCGTGTGGACAGCCGCAGTTTTTGGAAAAGTGCCG
ACAACACCGGATAATTTTTTGTTTCAAGCAGGCCCTATCTCCATTAACAGCGATAATGTGTCTGTCGGCATCTCTCTCGG
GTTTCGTATTTTATGCTTTTCCGCCTTATCGATGATGTTTGTTTTTACAACCGATCCGATTCTATTTATGCTGAGCCTTG
TCCAGCAGTGCAGGCTCTCACCAAAGCTCGCGTACGGTGTCATTGCAGGCTTTCGCTTTCTTCCGCTGTTAAAGGATGAG
GTCCAGCTGATTCAGCAGGCTCATAAAATCAGAGGAGGAGCGGCGGAGAGCGGCATCATTAATAAAATCAGTGCGTTAAA
ACGATATACCATACCGCTATTGGCAAGCGCCATCAGAAAAGCGGAACGGACAGCGCTTGCGATGGAATCGAAAGGATTTA
CAGGAAGCAGAAACCGGACATACTACAGGACATTGAGCGTGAACCGGCGCGACTGGGTGTTCTTTTGCCTCGTCCTCTTA
TTATTCGCGGGATCCTTTCTCGTATCTTTATGTTTCGCATCATAA

Upstream 100 bases:

>100_bases
CCAGCGCAGTTGTTTTCTCAAGAAACAGGGCTTGTTCAAAAAGCAAAGCTCACCCTTCCCCTTCTATATGAATGGATGGC
ATTTCAAGAGGAGGTGCGTG

Downstream 100 bases:

>100_bases
AAAATCCGCTATCACAGATAGCGGATTTTTTTATTGATGATAGTTTAATGCTTGGGCAAGGTTGGTTTTAATAGTAATAT
TCGAAAAGTCAATCCCCAGC

Product: thiamine transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKQPLHLINPTVKAAAVFCCVVMLSFIYNPYTPACFYIIIVAGVLLAAGIPLKKWLLFTIPFLILAFGCVWTAAVFGKVP
TTPDNFLFQAGPISINSDNVSVGISLGFRILCFSALSMMFVFTTDPILFMLSLVQQCRLSPKLAYGVIAGFRFLPLLKDE
VQLIQQAHKIRGGAAESGIINKISALKRYTIPLLASAIRKAERTALAMESKGFTGSRNRTYYRTLSVNRRDWVFFCLVLL
LFAGSFLVSLCFAS

Sequences:

>Translated_254_residues
MKQPLHLINPTVKAAAVFCCVVMLSFIYNPYTPACFYIIIVAGVLLAAGIPLKKWLLFTIPFLILAFGCVWTAAVFGKVP
TTPDNFLFQAGPISINSDNVSVGISLGFRILCFSALSMMFVFTTDPILFMLSLVQQCRLSPKLAYGVIAGFRFLPLLKDE
VQLIQQAHKIRGGAAESGIINKISALKRYTIPLLASAIRKAERTALAMESKGFTGSRNRTYYRTLSVNRRDWVFFCLVLL
LFAGSFLVSLCFAS
>Mature_254_residues
MKQPLHLINPTVKAAAVFCCVVMLSFIYNPYTPACFYIIIVAGVLLAAGIPLKKWLLFTIPFLILAFGCVWTAAVFGKVP
TTPDNFLFQAGPISINSDNVSVGISLGFRILCFSALSMMFVFTTDPILFMLSLVQQCRLSPKLAYGVIAGFRFLPLLKDE
VQLIQQAHKIRGGAAESGIINKISALKRYTIPLLASAIRKAERTALAMESKGFTGSRNRTYYRTLSVNRRDWVFFCLVLL
LFAGSFLVSLCFAS

Specific function: Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Probably responsible for the translocation of the substrate across the membrane (Probable)

COG id: COG0619

COG function: function code P; ABC-type cobalt transport system, permease component CbiQ and related transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiQ family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YKOC_BACSU (O34572)

Other databases:

- EMBL:   AJ002571
- EMBL:   AL009126
- PIR:   G69858
- RefSeq:   NP_389204.1
- EnsemblBacteria:   EBBACT00000000272
- GeneID:   939836
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU13210
- NMPDR:   fig|224308.1.peg.1323
- GenoList:   BSU13210
- GeneTree:   EBGT00050000002663
- HOGENOM:   HBG337947
- OMA:   QAGPISI
- ProtClustDB:   CLSK887170
- BioCyc:   BSUB:BSU13210-MONOMER
- InterPro:   IPR003339

Pfam domain/function: PF02361 CbiQ

EC number: NA

Molecular weight: Translated: 28042; Mature: 28042

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe9bb734)-; HASH(0xe9d69fc)-; HASH(0xe993fdc)-; HASH(0xe1d81b0)-; HASH(0xe92bc74)-;

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCH
>Mature Secondary Structure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HHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377