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The map label for this gene is yjmD

Identifier: 16078298

GI number: 16078298

Start: 1304442

End: 1305461

Strand: Direct

Name: yjmD

Synonym: BSU12330

Alternate gene names: 16078298

Gene position: 1304442-1305461 (Clockwise)

Preceding gene: 16078297

Following gene: 16078299

Centisome position: 30.94

GC content: 50.69

Gene sequence:

>1020_bases
ATGAAAGCGGTTCAAGTGCGAAAAGCGTATGATCTGGTGACAGCGGAGGTGAAGAAGCCAGTTCTTTCAAAGGATGATGA
AGTGCTCGTGAAAGTCAAGCGAGTCGGCATTTGCGGTTCAGACATGCACATTTATCATGGAACGAATCCGCTCGCTACCC
TCCCGAGAGTCATCGGACACGAGGTAACGGGACAAGTGGAGGCAGTTGGTGCGAATGTACAGAGCCTAAAACCCGGTGAT
CATGTGGTGATTGAGCCGATTTCTTATTGCGGATCGTGCTATGCCTGCCGCAAAGGGCGGCCGAATGTTTGCGCCAAGCT
TTCTGTATTTGGCGTACATGAGGACGGAGGCATGCGGGAATATATTGTGCTTCCGGAAAGACAGCTTCACGCGGTCTCAA
AGGACTTGCCTTGGGAGGAAGCAGTCATGGCCGAGCCTTATACGATAGGCGCCCAGGCAGTGTGGAGAGGCCAGGTGGAA
AAAGGTGATACCGTCCTGATCCAGGGAGCGGGGCCCATCGGGATCTGTGTGTTAAAAATGGCAAAACTGGCGGGCGCTGC
TGTCATGATGACTGACTTGAACAACGAGCGGCTGGCATTTGCGAAAGAAAACGGCGCCGATGCTGTTGTAAATGTCCAAG
CAGAACATGTTGCCGAGCGGGTCCTTGAATGGACTGGGAATGAAGGAGCAAACGTGGTCATTGATGCTGTTTGCCTGCCG
GAGACTTTTGCACTTTCAATTGAGGCTGTGTCACCGGCGGGACATGTGGTTGTGCTTGGATTTGATGAAAGAGCGGCTCA
GATTTCTCAGCTGCCAATTACAAAAAAAGAAGTCACGATAACCGGATCCCGATTGCAGACCAATCAGTTTCCAAAAGTGG
TAGAGCTTTTGAATGGAGGCCGGTTAATGCATAACGGGCTGGTGACCCATACATTTTCAGTTGATGACGTTCATCATGCA
TTTCAGTTTATTAAGGAGCATCCAGATCAGGTGCGGAAAGCCGTCATCACGTTTGATTAA

Upstream 100 bases:

>100_bases
TGCCCGGCGAGATCGAGCAGCTGCATGAAGAAAGAAATAAGAAAAACGGAATTTCTATCGCCCGGAGCGTGTATGAATTC
TTAAAAAGCAGGTGAGTAAA

Downstream 100 bases:

>100_bases
ATGACTGAATCCGGAGGTGCGAGCATGAATATGACATTCCGATGGTATGGACGAGGCAACGATACAGTCACACTTGAATA
CGTGAAGCAAATTCCCGGTG

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MKAVQVRKAYDLVTAEVKKPVLSKDDEVLVKVKRVGICGSDMHIYHGTNPLATLPRVIGHEVTGQVEAVGANVQSLKPGD
HVVIEPISYCGSCYACRKGRPNVCAKLSVFGVHEDGGMREYIVLPERQLHAVSKDLPWEEAVMAEPYTIGAQAVWRGQVE
KGDTVLIQGAGPIGICVLKMAKLAGAAVMMTDLNNERLAFAKENGADAVVNVQAEHVAERVLEWTGNEGANVVIDAVCLP
ETFALSIEAVSPAGHVVVLGFDERAAQISQLPITKKEVTITGSRLQTNQFPKVVELLNGGRLMHNGLVTHTFSVDDVHHA
FQFIKEHPDQVRKAVITFD

Sequences:

>Translated_339_residues
MKAVQVRKAYDLVTAEVKKPVLSKDDEVLVKVKRVGICGSDMHIYHGTNPLATLPRVIGHEVTGQVEAVGANVQSLKPGD
HVVIEPISYCGSCYACRKGRPNVCAKLSVFGVHEDGGMREYIVLPERQLHAVSKDLPWEEAVMAEPYTIGAQAVWRGQVE
KGDTVLIQGAGPIGICVLKMAKLAGAAVMMTDLNNERLAFAKENGADAVVNVQAEHVAERVLEWTGNEGANVVIDAVCLP
ETFALSIEAVSPAGHVVVLGFDERAAQISQLPITKKEVTITGSRLQTNQFPKVVELLNGGRLMHNGLVTHTFSVDDVHHA
FQFIKEHPDQVRKAVITFD
>Mature_339_residues
MKAVQVRKAYDLVTAEVKKPVLSKDDEVLVKVKRVGICGSDMHIYHGTNPLATLPRVIGHEVTGQVEAVGANVQSLKPGD
HVVIEPISYCGSCYACRKGRPNVCAKLSVFGVHEDGGMREYIVLPERQLHAVSKDLPWEEAVMAEPYTIGAQAVWRGQVE
KGDTVLIQGAGPIGICVLKMAKLAGAAVMMTDLNNERLAFAKENGADAVVNVQAEHVAERVLEWTGNEGANVVIDAVCLP
ETFALSIEAVSPAGHVVVLGFDERAAQISQLPITKKEVTITGSRLQTNQFPKVVELLNGGRLMHNGLVTHTFSVDDVHHA
FQFIKEHPDQVRKAVITFD

Specific function: Not Known; Probable Catabolic Enzyme. [C]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family

Homologues:

Organism=Homo sapiens, GI156627571, Length=308, Percent_Identity=33.4415584415584, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI4501929, Length=366, Percent_Identity=26.775956284153, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI34577061, Length=365, Percent_Identity=26.3013698630137, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI4501933, Length=365, Percent_Identity=26.027397260274, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI262073058, Length=367, Percent_Identity=26.4305177111717, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI71743840, Length=367, Percent_Identity=26.4305177111717, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI4501939, Length=347, Percent_Identity=25.9365994236311, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI156523966, Length=347, Percent_Identity=25.9365994236311, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI71565154, Length=333, Percent_Identity=25.8258258258258, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI71565152, Length=347, Percent_Identity=23.0547550432277, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1787863, Length=341, Percent_Identity=39.5894428152493, Blast_Score=248, Evalue=6e-67,
Organism=Escherichia coli, GI226510992, Length=339, Percent_Identity=32.7433628318584, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1788073, Length=342, Percent_Identity=31.5789473684211, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1790045, Length=346, Percent_Identity=29.7687861271676, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1788407, Length=327, Percent_Identity=30.2752293577982, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI87082125, Length=342, Percent_Identity=29.8245614035088, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1790718, Length=312, Percent_Identity=29.1666666666667, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1786825, Length=265, Percent_Identity=28.3018867924528, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788075, Length=343, Percent_Identity=25.9475218658892, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786552, Length=350, Percent_Identity=28, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI87081918, Length=296, Percent_Identity=30.4054054054054, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17562876, Length=307, Percent_Identity=33.2247557003257, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17562878, Length=304, Percent_Identity=32.2368421052632, Blast_Score=154, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI25146526, Length=376, Percent_Identity=25.531914893617, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71997431, Length=378, Percent_Identity=25.3968253968254, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17565904, Length=329, Percent_Identity=25.8358662613982, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71988145, Length=248, Percent_Identity=29.4354838709677, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562582, Length=268, Percent_Identity=25.7462686567164, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562584, Length=269, Percent_Identity=25.6505576208178, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323099, Length=348, Percent_Identity=29.0229885057471, Blast_Score=136, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6319258, Length=381, Percent_Identity=27.2965879265092, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6322619, Length=346, Percent_Identity=27.1676300578035, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6319955, Length=346, Percent_Identity=26.878612716763, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319257, Length=327, Percent_Identity=29.0519877675841, Blast_Score=119, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6320033, Length=373, Percent_Identity=26.0053619302949, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323729, Length=267, Percent_Identity=28.4644194756554, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6319621, Length=266, Percent_Identity=28.1954887218045, Blast_Score=82, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6323961, Length=276, Percent_Identity=27.8985507246377, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324486, Length=276, Percent_Identity=27.8985507246377, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI17737897, Length=307, Percent_Identity=34.5276872964169, Blast_Score=141, Evalue=5e-34,
Organism=Drosophila melanogaster, GI17137530, Length=307, Percent_Identity=33.5504885993485, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI45551930, Length=329, Percent_Identity=26.4437689969605, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI221457811, Length=329, Percent_Identity=26.4437689969605, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI45550770, Length=329, Percent_Identity=26.4437689969605, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI17737895, Length=369, Percent_Identity=25.7452574525745, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YJMD_BACSU (O35045)

Other databases:

- EMBL:   AF015825
- EMBL:   AL009126
- PIR:   F69852
- RefSeq:   NP_389115.1
- HSSP:   Q00796
- ProteinModelPortal:   O35045
- SMR:   O35045
- EnsemblBacteria:   EBBACT00000003570
- GeneID:   936463
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU12330
- NMPDR:   fig|224308.1.peg.1234
- GenoList:   BSU12330
- GeneTree:   EBGT00050000000383
- HOGENOM:   HBG753318
- OMA:   KGRPNVC
- PhylomeDB:   O35045
- ProtClustDB:   CLSK887107
- BioCyc:   BSUB:BSU12330-MONOMER
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR11695

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N; SSF50129 GroES_like

EC number: 1.1.1.- [C]

Molecular weight: Translated: 36763; Mature: 36763

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVQVRKAYDLVTAEVKKPVLSKDDEVLVKVKRVGICGSDMHIYHGTNPLATLPRVIGH
CCCEEHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCEEEEECCCHHHHHHHHHCC
EVTGQVEAVGANVQSLKPGDHVVIEPISYCGSCYACRKGRPNVCAKLSVFGVHEDGGMRE
CCCCCEEEECCCHHCCCCCCEEEEEEHHHCCCEEEECCCCCCCEEEEEEEEEECCCCCEE
YIVLPERQLHAVSKDLPWEEAVMAEPYTIGAQAVWRGQVEKGDTVLIQGAGPIGICVLKM
EEECCHHHHHHHHCCCCHHHHHCCCCEEECCCEEEECCCCCCCEEEEECCCCHHHHHHHH
AKLAGAAVMMTDLNNERLAFAKENGADAVVNVQAEHVAERVLEWTGNEGANVVIDAVCLP
HHHCCCEEEEEECCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHCCCCCCCEEEEEEECC
ETFALSIEAVSPAGHVVVLGFDERAAQISQLPITKKEVTITGSRLQTNQFPKVVELLNGG
CEEEEEEEEECCCCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHCCC
RLMHNGLVTHTFSVDDVHHAFQFIKEHPDQVRKAVITFD
EEEECCEEEEEECHHHHHHHHHHHHHCHHHHHHEEEECC
>Mature Secondary Structure
MKAVQVRKAYDLVTAEVKKPVLSKDDEVLVKVKRVGICGSDMHIYHGTNPLATLPRVIGH
CCCEEHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCEEEEECCCHHHHHHHHHCC
EVTGQVEAVGANVQSLKPGDHVVIEPISYCGSCYACRKGRPNVCAKLSVFGVHEDGGMRE
CCCCCEEEECCCHHCCCCCCEEEEEEHHHCCCEEEECCCCCCCEEEEEEEEEECCCCCEE
YIVLPERQLHAVSKDLPWEEAVMAEPYTIGAQAVWRGQVEKGDTVLIQGAGPIGICVLKM
EEECCHHHHHHHHCCCCHHHHHCCCCEEECCCEEEECCCCCCCEEEEECCCCHHHHHHHH
AKLAGAAVMMTDLNNERLAFAKENGADAVVNVQAEHVAERVLEWTGNEGANVVIDAVCLP
HHHCCCEEEEEECCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHCCCCCCCEEEEEEECC
ETFALSIEAVSPAGHVVVLGFDERAAQISQLPITKKEVTITGSRLQTNQFPKVVELLNGG
CEEEEEEEEECCCCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHCCC
RLMHNGLVTHTFSVDDVHHAFQFIKEHPDQVRKAVITFD
EEEECCEEEEEECHHHHHHHHHHHHHCHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377