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The map label for this gene is yitG

Identifier: 16078162

GI number: 16078162

Start: 1175985

End: 1177253

Strand: Reverse

Name: yitG

Synonym: BSU10980

Alternate gene names: 16078162

Gene position: 1177253-1175985 (Counterclockwise)

Preceding gene: 16078163

Following gene: 16078161

Centisome position: 27.93

GC content: 45.63

Gene sequence:

>1269_bases
ATGGAATCATCAAAACAAAATAACGGAATGACGATTGTGGCAATCGGTTCAATCCCTTTAATATTAACCCTAGGAAACTC
GATGCTTATTCCGATTTTGCCAAAAATGAAATCTGAACTTCATTTATCACAATTTCAAGTCAGTCTCGTGATCACAGTAT
TTTCCTTGATTGCAGCATTTGCGATTCCGATTGTCGGTTATCTCGCAGACCGATTCTCAAGGAAAGTCATCATTATTCCC
TGCTTAATTTTGTATGGTGCCGGCGGTTTGTTAGCCGGGTTTGCGGCAGGTTTTTTTGACAATGCCTATCCTTGGGTCAT
GGCAGGACGAGCGTTACAGGGAATCGGGGCAGCCGGAACCGGCCCAATTGCCATGGCACTGACGGGAGATCTGTTTAAAG
GCGCCCAGGAGAGCAAGGTGCTCGGCCTTGTTGAAGCTTCAAACGGCATGGGGAAAGTGCTATCGCCGATCATTGGCTCG
CTGATCGCCCTGCTTGTCTGGTATGGCGCGTTTTTTGCCTTTCCTGTGTTTTGTATCATTTCGATCGTACTGACTTGGAT
TTTTATTAAAGAAAAGAAAAAGGAAAAAGAACCGCCACCAATCGGACAATATGCAAAAGGGCTGTTAAGTGTCTTTAAAC
ATGAAGGCAGATGGCTGTTTACCGCTTATTTAGCCGGTGCGACCTGTTTGTTTACTTTATTCGGCATCCTGTTTTATCTC
TCAGATGTTCTTGAAAAAACATACGACACCGACGGCGTGAAAAAAGGCTTAATTTTAGCGATCCCGCTTTTGGTTATGTG
TGTGACGTCCTATACAACAGGAAGCAAAATCGGGCAAAAGCAATCGTTAATGAAAAAGCTGATCGTACTTGGATTGGCGT
TCATGACCGTATCCTACGCGGCACTGTCATTCATTGAAAATCTTGTCCTTTTTATCAGTGTTCTTGTACTGAGCAGTATA
GGCTCAGGTCTTGTCCTTCCTTGTGTGAACAGTTTCATTACCGGGGCTGTCGGCAAAGAAAGACGGGGATTTGTCACCTC
GCTGTACGGCTCTGTACGTTTCTTAGGGGTAGCGATCGGTCCTCCGATTTTCGGCCGCCTGATGCAATGGTCCAGACCCG
GCATGTTTTTAAGCATCGCGGGATTGACTCTCGTTGTCGGGATTCTTGTGATGATGCTCATCCATGTGAAGCAAAACAAT
GAAGAAACAAAAGAAAAAGAAGACCCTAAAATGGCTGGCAATCGGCTCCAGCCCGCTGAGGAAAGGTAG

Upstream 100 bases:

>100_bases
CCCGAACAGGTATCTTCTGTTCGGTTTTTTGCTGTCTGATCGCTGAATAAACGAAGCCATCAGGGACATTCTAAGCAGAA
GAAAAGGAGTGTGCTCTGAG

Downstream 100 bases:

>100_bases
CACCCAGTGTGAAAATTGTACGGATTGAAACCTTTCCGCTATTTCATCGATTAGAAAAGCCATACGGAGATGCCAATGGG
TTTAAACGATATCGGACTTG

Product: efflux transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MESSKQNNGMTIVAIGSIPLILTLGNSMLIPILPKMKSELHLSQFQVSLVITVFSLIAAFAIPIVGYLADRFSRKVIIIP
CLILYGAGGLLAGFAAGFFDNAYPWVMAGRALQGIGAAGTGPIAMALTGDLFKGAQESKVLGLVEASNGMGKVLSPIIGS
LIALLVWYGAFFAFPVFCIISIVLTWIFIKEKKKEKEPPPIGQYAKGLLSVFKHEGRWLFTAYLAGATCLFTLFGILFYL
SDVLEKTYDTDGVKKGLILAIPLLVMCVTSYTTGSKIGQKQSLMKKLIVLGLAFMTVSYAALSFIENLVLFISVLVLSSI
GSGLVLPCVNSFITGAVGKERRGFVTSLYGSVRFLGVAIGPPIFGRLMQWSRPGMFLSIAGLTLVVGILVMMLIHVKQNN
EETKEKEDPKMAGNRLQPAEER

Sequences:

>Translated_422_residues
MESSKQNNGMTIVAIGSIPLILTLGNSMLIPILPKMKSELHLSQFQVSLVITVFSLIAAFAIPIVGYLADRFSRKVIIIP
CLILYGAGGLLAGFAAGFFDNAYPWVMAGRALQGIGAAGTGPIAMALTGDLFKGAQESKVLGLVEASNGMGKVLSPIIGS
LIALLVWYGAFFAFPVFCIISIVLTWIFIKEKKKEKEPPPIGQYAKGLLSVFKHEGRWLFTAYLAGATCLFTLFGILFYL
SDVLEKTYDTDGVKKGLILAIPLLVMCVTSYTTGSKIGQKQSLMKKLIVLGLAFMTVSYAALSFIENLVLFISVLVLSSI
GSGLVLPCVNSFITGAVGKERRGFVTSLYGSVRFLGVAIGPPIFGRLMQWSRPGMFLSIAGLTLVVGILVMMLIHVKQNN
EETKEKEDPKMAGNRLQPAEER
>Mature_422_residues
MESSKQNNGMTIVAIGSIPLILTLGNSMLIPILPKMKSELHLSQFQVSLVITVFSLIAAFAIPIVGYLADRFSRKVIIIP
CLILYGAGGLLAGFAAGFFDNAYPWVMAGRALQGIGAAGTGPIAMALTGDLFKGAQESKVLGLVEASNGMGKVLSPIIGS
LIALLVWYGAFFAFPVFCIISIVLTWIFIKEKKKEKEPPPIGQYAKGLLSVFKHEGRWLFTAYLAGATCLFTLFGILFYL
SDVLEKTYDTDGVKKGLILAIPLLVMCVTSYTTGSKIGQKQSLMKKLIVLGLAFMTVSYAALSFIENLVLFISVLVLSSI
GSGLVLPCVNSFITGAVGKERRGFVTSLYGSVRFLGVAIGPPIFGRLMQWSRPGMFLSIAGLTLVVGILVMMLIHVKQNN
EETKEKEDPKMAGNRLQPAEER

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily

Homologues:

Organism=Escherichia coli, GI1790146, Length=170, Percent_Identity=28.8235294117647, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YITG_BACSU (Q796Q1)

Other databases:

- EMBL:   AL009126
- RefSeq:   NP_388979.1
- ProteinModelPortal:   Q796Q1
- EnsemblBacteria:   EBBACT00000000295
- GeneID:   939791
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU10980
- NMPDR:   fig|224308.1.peg.1098
- GenoList:   BSU10980
- GeneTree:   EBGT00070000031854
- HOGENOM:   HBG337996
- OMA:   TGDLFKG
- ProtClustDB:   CLSK2518218
- BioCyc:   BSUB:BSU10980-MONOMER
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001958
- PRINTS:   PR01035

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 45508; Mature: 45508

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe193da0)-; HASH(0xdb139cc)-; HASH(0xc8496fc)-; HASH(0xcbac730)-; HASH(0xe34e560)-; HASH(0xbd0f37c)-; HASH(0xb8c6bc0)-; HASH(0xe08e778)-; HASH(0xdd5f85c)-; HASH(0xe07a5ec)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESSKQNNGMTIVAIGSIPLILTLGNSMLIPILPKMKSELHLSQFQVSLVITVFSLIAAF
CCCCCCCCCEEEEEECCCCEEEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIPIVGYLADRFSRKVIIIPCLILYGAGGLLAGFAAGFFDNAYPWVMAGRALQGIGAAGT
HHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
GPIAMALTGDLFKGAQESKVLGLVEASNGMGKVLSPIIGSLIALLVWYGAFFAFPVFCII
CCCCCCEECHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIVLTWIFIKEKKKEKEPPPIGQYAKGLLSVFKHEGRWLFTAYLAGATCLFTLFGILFYL
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHH
SDVLEKTYDTDGVKKGLILAIPLLVMCVTSYTTGSKIGQKQSLMKKLIVLGLAFMTVSYA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHH
ALSFIENLVLFISVLVLSSIGSGLVLPCVNSFITGAVGKERRGFVTSLYGSVRFLGVAIG
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHC
PPIFGRLMQWSRPGMFLSIAGLTLVVGILVMMLIHVKQNNEETKEKEDPKMAGNRLQPAE
CHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHCCCCCCCCC
ER
CH
>Mature Secondary Structure
MESSKQNNGMTIVAIGSIPLILTLGNSMLIPILPKMKSELHLSQFQVSLVITVFSLIAAF
CCCCCCCCCEEEEEECCCCEEEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIPIVGYLADRFSRKVIIIPCLILYGAGGLLAGFAAGFFDNAYPWVMAGRALQGIGAAGT
HHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
GPIAMALTGDLFKGAQESKVLGLVEASNGMGKVLSPIIGSLIALLVWYGAFFAFPVFCII
CCCCCCEECHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIVLTWIFIKEKKKEKEPPPIGQYAKGLLSVFKHEGRWLFTAYLAGATCLFTLFGILFYL
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHH
SDVLEKTYDTDGVKKGLILAIPLLVMCVTSYTTGSKIGQKQSLMKKLIVLGLAFMTVSYA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHH
ALSFIENLVLFISVLVLSSIGSGLVLPCVNSFITGAVGKERRGFVTSLYGSVRFLGVAIG
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHC
PPIFGRLMQWSRPGMFLSIAGLTLVVGILVMMLIHVKQNNEETKEKEDPKMAGNRLQPAE
CHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHCCCCCCCCC
ER
CH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377