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The map label for this gene is yisP

Identifier: 16078144

GI number: 16078144

Start: 1159922

End: 1160746

Strand: Direct

Name: yisP

Synonym: BSU10810

Alternate gene names: 16078144

Gene position: 1159922-1160746 (Clockwise)

Preceding gene: 50812210

Following gene: 16078146

Centisome position: 27.51

GC content: 46.79

Gene sequence:

>825_bases
GTGATACATAGGAGTGAGAAAATGAAAGAGATAAAAGAAGCTTACCAGCAATGCGGACAGATTGTTGGCGAATACGCGCC
AGCCTGTTTCAAAGCATTATCATATCTCCCGCTAAAGCAAAGACAAGCCTCTTGGGCAGTATTGTCGTTTTGCCACACGG
CGGCCAGTGCAGACGAAAAGGTATTGCCCGCATTTGAAGCTAAAGCTGATCATGTTTACCAAAGGACAAATAACGGTAAA
CAACATCTATGGAAGGCTTTTGATCATGCGTATCGGACCTTTACATTGGAAAGCGAACCTTTTCGGGAGTTTATTGCCGC
ACAAAAAGAAGACGCCAAGCCGTATGATGACCTTGATGAACTGCTCATGTACGCATATCGGACGGGCGGTGCTGCCGGAT
TGATGCTGCTGCCGATACTGACACGCCGAAAACAAGATCAGCTCAAACAAGCAGCCGTCTCTCTCGGCTTGGCCATACAG
CTGGTTCGCTTCTTAAGTGATCTTGGCACAGATCAGCAAAAAAACCGCATTCCCCGTCAGGTAATGCAGCAATTCGGCTA
TACAGAGGCTGATCTCCAAAAAGGCACCGTAAATAAAGCGTTCACAATGACGTGGGAGTATATCGCTTTTGAAGCAGAAG
CCTACCTTGAAGAGTGTCAGGATGCCTTGCCGCTATTTCCGCAGTATTCTCAAAAAACGGTGAAAGCCGCTCTTCATTTG
CACCGGGCTGTTTTAGAAAAAATCCGGGCGAAGCAGCACGATGTATTTCAATATCACTTCGCTCTCACAGAGACCGAAGT
GAAGCAGATTCTGTCTGATATCTAA

Upstream 100 bases:

>100_bases
TCTCGTCGATGATGCTGTGCGTCTTGTTACTTTTACAAAGTAAGAATCGGCATTTTCTTCATATACAATTAGGAAAAAAC
ATACTAGACTTGAAGAAGCA

Downstream 100 bases:

>100_bases
AAAACACCCGGCCTTGATTGAGCCGGGTGTTACGCCATACCTTTTTGAATCCAGATACGTGAGCGCCATCTTCTGTACAT
TAAGATTCCCCGGACCCATT

Product: squalene/phytoene synthase

Products: diphosphate; prephytoene diphosphate

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MIHRSEKMKEIKEAYQQCGQIVGEYAPACFKALSYLPLKQRQASWAVLSFCHTAASADEKVLPAFEAKADHVYQRTNNGK
QHLWKAFDHAYRTFTLESEPFREFIAAQKEDAKPYDDLDELLMYAYRTGGAAGLMLLPILTRRKQDQLKQAAVSLGLAIQ
LVRFLSDLGTDQQKNRIPRQVMQQFGYTEADLQKGTVNKAFTMTWEYIAFEAEAYLEECQDALPLFPQYSQKTVKAALHL
HRAVLEKIRAKQHDVFQYHFALTETEVKQILSDI

Sequences:

>Translated_274_residues
MIHRSEKMKEIKEAYQQCGQIVGEYAPACFKALSYLPLKQRQASWAVLSFCHTAASADEKVLPAFEAKADHVYQRTNNGK
QHLWKAFDHAYRTFTLESEPFREFIAAQKEDAKPYDDLDELLMYAYRTGGAAGLMLLPILTRRKQDQLKQAAVSLGLAIQ
LVRFLSDLGTDQQKNRIPRQVMQQFGYTEADLQKGTVNKAFTMTWEYIAFEAEAYLEECQDALPLFPQYSQKTVKAALHL
HRAVLEKIRAKQHDVFQYHFALTETEVKQILSDI
>Mature_274_residues
MIHRSEKMKEIKEAYQQCGQIVGEYAPACFKALSYLPLKQRQASWAVLSFCHTAASADEKVLPAFEAKADHVYQRTNNGK
QHLWKAFDHAYRTFTLESEPFREFIAAQKEDAKPYDDLDELLMYAYRTGGAAGLMLLPILTRRKQDQLKQAAVSLGLAIQ
LVRFLSDLGTDQQKNRIPRQVMQQFGYTEADLQKGTVNKAFTMTWEYIAFEAEAYLEECQDALPLFPQYSQKTVKAALHL
HRAVLEKIRAKQHDVFQYHFALTETEVKQILSDI

Specific function: Unknown

COG id: COG1562

COG function: function code I; Phytoene/squalene synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phytoene/squalene synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002060
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00494 SQS_PSY [H]

EC number: 2.5.1.32

Molecular weight: Translated: 31503; Mature: 31503

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHRSEKMKEIKEAYQQCGQIVGEYAPACFKALSYLPLKQRQASWAVLSFCHTAASADEK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCH
VLPAFEAKADHVYQRTNNGKQHLWKAFDHAYRTFTLESEPFREFIAAQKEDAKPYDDLDE
HCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHH
LLMYAYRTGGAAGLMLLPILTRRKQDQLKQAAVSLGLAIQLVRFLSDLGTDQQKNRIPRQ
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VMQQFGYTEADLQKGTVNKAFTMTWEYIAFEAEAYLEECQDALPLFPQYSQKTVKAALHL
HHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
HRAVLEKIRAKQHDVFQYHFALTETEVKQILSDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: geranylgeranyl diphosphate

Specific reaction: 2 geranylgeranyl diphosphate = diphosphate + prephytoene diphosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]