Click here to switch to the map view.

The map label for this gene is hemAT

Identifier: 16078102

GI number: 16078102

Start: 1112620

End: 1113918

Strand: Reverse

Name: hemAT

Synonym: BSU10380

Alternate gene names: 16078102

Gene position: 1113918-1112620 (Counterclockwise)

Preceding gene: 16078103

Following gene: 16078101

Centisome position: 26.42

GC content: 41.19

Gene sequence:

>1299_bases
TTGTTATTTAAAAAAGACAGAAAACAAGAAACAGCTTACTTTTCAGATTCAAACGGACAACAAAAAAACCGCATTCAGCT
CACAAACAAACATGCAGATGTCAAAAAACAGCTCAAAATGGTCAGGTTGGGAGATGCTGAGCTTTATGTGTTAGAGCAGC
TTCAGCCACTCATTCAAGAAAATATCGTAAATATCGTCGATGCGTTTTATAAAAACCTTGACCATGAAAGCTCATTGATG
GATATCATTAATGATCACAGCTCAGTTGACCGCTTAAAACAAACGTTAAAACGGCATATTCAGGAAATGTTTGCAGGCGT
TATCGATGATGAATTTATTGAAAAGCGTAACCGAATCGCCTCCATCCATTTAAGAATCGGCCTTTTGCCAAAATGGTATA
TGGGTGCGTTTCAAGAGCTCCTTTTGTCAATGATTGACATTTATGAAGCGTCCATTACAAATCAGCAAGAACTGCTAAAA
GCCATTAAAGCAACAACAAAAATCTTGAACTTAGAACAGCAGCTTGTCCTTGAAGCGTTTCAAAGCGAGTACAACCAGAC
CCGTGATGAACAAGAAGAAAAGAAAAACCTTCTTCATCAGAAAATTCAAGAAACCTCTGGATCGATTGCCAATCTGTTTT
CAGAAACAAGCAGATCAGTTCAAGAGCTTGTGGACAAATCTGAAGGCATTTCTCAAGCATCCAAAGCCGGCACTGTAACA
TCCAGCACTGTTGAAGAAAAGTCGATCGGCGGAAAAAAAGAGCTAGAAGTCCAGCAAAAACAGATGAACAAAATTGACAC
AAGCCTTGTCCAAATCGAAAAAGAAATGGTCAAGCTGGATGAAATCGCGCAGCAAATTGAAAAAATCTTCGGCATCGTCA
CAGGCATAGCTGAACAAACAAACCTTCTCTCGCTCAATGCATCTATTGAATCCGCCCGCGCCGGAGAACACGGCAAAGGC
TTTGCTGTCGTGGCAAATGAAGTGCGGAAGCTTTCTGAGGATACGAAAAAAACCGTCTCTACTGTTTCTGAGCTTGTGAA
CAATACGAATACACAAATCAACATTGTATCCAAGCATATCAAAGACGTGAATGAGCTAGTCAGCGAAAGTAAAGAAAAAA
TGACGCAAATTAACCGCTTATTCGATGAAATCGTCCACAGCATGAAAATCAGCAAAGAGCAATCAGGCAAAATCGACGTC
GATCTGCAAGCCTTTCTTGGAGGGCTTCAGGAAGTCAGCCGCGCCGTTTCCCATGTGGCCGCTTCCGTTGATTCGCTTGT
CATCCTGACAGAAGAATAA

Upstream 100 bases:

>100_bases
ATCTGCAGCTTCATTCATGTTTCCCTTGGCCGATAAAAAAGAAAAAGGCTTAAAAAGCCAAAAAGTAAAAATTATATTTT
TCCCAAGGGGGATCATTGTA

Downstream 100 bases:

>100_bases
CCATCAAAAACCGGTCTGCCATACGGCCGGTTTTTTTGCGTTCATTATGTAAACTTAAATTAAAAATCAGTTGACATAAT
AATTACCTGCATTTATTGTA

Product: haem-based dioxygen sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MLFKKDRKQETAYFSDSNGQQKNRIQLTNKHADVKKQLKMVRLGDAELYVLEQLQPLIQENIVNIVDAFYKNLDHESSLM
DIINDHSSVDRLKQTLKRHIQEMFAGVIDDEFIEKRNRIASIHLRIGLLPKWYMGAFQELLLSMIDIYEASITNQQELLK
AIKATTKILNLEQQLVLEAFQSEYNQTRDEQEEKKNLLHQKIQETSGSIANLFSETSRSVQELVDKSEGISQASKAGTVT
SSTVEEKSIGGKKELEVQQKQMNKIDTSLVQIEKEMVKLDEIAQQIEKIFGIVTGIAEQTNLLSLNASIESARAGEHGKG
FAVVANEVRKLSEDTKKTVSTVSELVNNTNTQINIVSKHIKDVNELVSESKEKMTQINRLFDEIVHSMKISKEQSGKIDV
DLQAFLGGLQEVSRAVSHVAASVDSLVILTEE

Sequences:

>Translated_432_residues
MLFKKDRKQETAYFSDSNGQQKNRIQLTNKHADVKKQLKMVRLGDAELYVLEQLQPLIQENIVNIVDAFYKNLDHESSLM
DIINDHSSVDRLKQTLKRHIQEMFAGVIDDEFIEKRNRIASIHLRIGLLPKWYMGAFQELLLSMIDIYEASITNQQELLK
AIKATTKILNLEQQLVLEAFQSEYNQTRDEQEEKKNLLHQKIQETSGSIANLFSETSRSVQELVDKSEGISQASKAGTVT
SSTVEEKSIGGKKELEVQQKQMNKIDTSLVQIEKEMVKLDEIAQQIEKIFGIVTGIAEQTNLLSLNASIESARAGEHGKG
FAVVANEVRKLSEDTKKTVSTVSELVNNTNTQINIVSKHIKDVNELVSESKEKMTQINRLFDEIVHSMKISKEQSGKIDV
DLQAFLGGLQEVSRAVSHVAASVDSLVILTEE
>Mature_432_residues
MLFKKDRKQETAYFSDSNGQQKNRIQLTNKHADVKKQLKMVRLGDAELYVLEQLQPLIQENIVNIVDAFYKNLDHESSLM
DIINDHSSVDRLKQTLKRHIQEMFAGVIDDEFIEKRNRIASIHLRIGLLPKWYMGAFQELLLSMIDIYEASITNQQELLK
AIKATTKILNLEQQLVLEAFQSEYNQTRDEQEEKKNLLHQKIQETSGSIANLFSETSRSVQELVDKSEGISQASKAGTVT
SSTVEEKSIGGKKELEVQQKQMNKIDTSLVQIEKEMVKLDEIAQQIEKIFGIVTGIAEQTNLLSLNASIESARAGEHGKG
FAVVANEVRKLSEDTKKTVSTVSELVNNTNTQINIVSKHIKDVNELVSESKEKMTQINRLFDEIVHSMKISKEQSGKIDV
DLQAFLGGLQEVSRAVSHVAASVDSLVILTEE

Specific function: Heme-containing signal transducer responsible for aerotaxis, the migratory response toward or away from oxygen

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain

Homologues:

Organism=Escherichia coli, GI2367378, Length=117, Percent_Identity=36.7521367521368, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788195, Length=126, Percent_Identity=34.1269841269841, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788194, Length=147, Percent_Identity=36.0544217687075, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789453, Length=112, Percent_Identity=34.8214285714286, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787690, Length=144, Percent_Identity=31.25, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HEMAT_BACSU (O07621)

Other databases:

- EMBL:   Y14084
- EMBL:   AL009126
- PIR:   C69832
- RefSeq:   NP_388919.1
- PDB:   1OR4
- PDB:   1OR6
- PDBsum:   1OR4
- PDBsum:   1OR6
- ProteinModelPortal:   O07621
- EnsemblBacteria:   EBBACT00000000625
- GeneID:   936320
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU10380
- NMPDR:   fig|224308.1.peg.1038
- GenoList:   BSU10380
- GeneTree:   EBGT00050000000145
- HOGENOM:   HBG535222
- OMA:   ITEKFYT
- ProtClustDB:   CLSK2393374
- BioCyc:   BSUB:BSU10380-MONOMER
- GO:   GO:0016020
- GO:   GO:0009454
- InterPro:   IPR004089
- InterPro:   IPR012292
- InterPro:   IPR009050
- Gene3D:   G3DSA:1.10.490.10
- SMART:   SM00283

Pfam domain/function: PF00015 MCPsignal; SSF46458 Globin_like

EC number: NA

Molecular weight: Translated: 48768; Mature: 48768

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFKKDRKQETAYFSDSNGQQKNRIQLTNKHADVKKQLKMVRLGDAELYVLEQLQPLIQE
CCCCCCCCHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
NIVNIVDAFYKNLDHESSLMDIINDHSSVDRLKQTLKRHIQEMFAGVIDDEFIEKRNRIA
HHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
SIHLRIGLLPKWYMGAFQELLLSMIDIYEASITNQQELLKAIKATTKILNLEQQLVLEAF
EHHHEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QSEYNQTRDEQEEKKNLLHQKIQETSGSIANLFSETSRSVQELVDKSEGISQASKAGTVT
HHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
SSTVEEKSIGGKKELEVQQKQMNKIDTSLVQIEKEMVKLDEIAQQIEKIFGIVTGIAEQT
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NLLSLNASIESARAGEHGKGFAVVANEVRKLSEDTKKTVSTVSELVNNTNTQINIVSKHI
CEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHH
KDVNELVSESKEKMTQINRLFDEIVHSMKISKEQSGKIDVDLQAFLGGLQEVSRAVSHVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHH
ASVDSLVILTEE
HHHCCEEEEECC
>Mature Secondary Structure
MLFKKDRKQETAYFSDSNGQQKNRIQLTNKHADVKKQLKMVRLGDAELYVLEQLQPLIQE
CCCCCCCCHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
NIVNIVDAFYKNLDHESSLMDIINDHSSVDRLKQTLKRHIQEMFAGVIDDEFIEKRNRIA
HHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
SIHLRIGLLPKWYMGAFQELLLSMIDIYEASITNQQELLKAIKATTKILNLEQQLVLEAF
EHHHEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QSEYNQTRDEQEEKKNLLHQKIQETSGSIANLFSETSRSVQELVDKSEGISQASKAGTVT
HHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
SSTVEEKSIGGKKELEVQQKQMNKIDTSLVQIEKEMVKLDEIAQQIEKIFGIVTGIAEQT
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NLLSLNASIESARAGEHGKGFAVVANEVRKLSEDTKKTVSTVSELVNNTNTQINIVSKHI
CEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHH
KDVNELVSESKEKMTQINRLFDEIVHSMKISKEQSGKIDVDLQAFLGGLQEVSRAVSHVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHH
ASVDSLVILTEE
HHHCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 10676961; 11821422