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The map label for this gene is yhdY

Identifier: 16078029

GI number: 16078029

Start: 1038909

End: 1040024

Strand: Direct

Name: yhdY

Synonym: BSU09640

Alternate gene names: 16078029

Gene position: 1038909-1040024 (Clockwise)

Preceding gene: 16078028

Following gene: 16078030

Centisome position: 24.64

GC content: 43.37

Gene sequence:

>1116_bases
ATGCCGGATTATCTGCAGCAGTATTTTACGCTTGATAACATCATACAAATCGGCATCAGCTTGGCGATTTTGCTGGTGTT
TCTTATACTTAGAAAATTATTCACAAGATATTTTTTTAACCTGCTTTTTAATTTGACAAACCGGCCGAAAACAGAAATTT
TTAAACAGGTGGTTCTGGCGTTTGATAAGCCGGCCAGATGGTTTTTTGTTGCCCTTGGGCTGTTTTTAGCGATCCGGTAT
TCACCGTTTTTAGATGAGCAAATGCCGGTCATCAGCAAAATATACCGCTCACTGATTGTGGCGCTCTTGTGTTGGGGTCT
TTGTAATTTGACCGCAACATCGTCGTTTATCTTCCATAAGGTGAACCAGCGCTTCGAGCTTGACATGGATGACATTCTGG
CCCCGTTTTTATCCAAATTGCTCCGTTTTGTGATCATTGCGCTCAGTGTCAGTGTGATCGCTCAGGAATTCAATTATGAT
GTCAACGGATTTGTAGCGGGCCTTGGTCTTGGCGGACTGGCTTTTGCGCTTGCCGCGAAGGATACCATCAGCAACTTCTT
CGGCGGTATTATCATTATTACTGAAAAGCCGTTTACAATTGGTGACTGGGTGGAGACGTCGACAGTAACAGGATCAGTCG
AGGATATTACCTTTAGGAGCACGAGATTCAGAACAGCACAGGGGGCGCTTGTAACGGTGCCGAACTCTACGCTGTCGATG
GAAGCGATCACGAACTGGACAAGAATGACCAAACGCCAGATTACGTTTTCCATCCATGTGTCCTACGCTACGCCGATTGA
GAACCTTGAACGCTCCATTCATTCTCTCAGAACAATGCTCTTAGAGCATGAGGGCGTTGATAATGAAATAATCATGGTCA
ACTTTGATACGTTTGCCGACAGCTACTACAATTTATTTTTTAACTTCTATACAAAAACGACGGTTTGGGCTGAAAACCTT
AATATTAGAGAGGATATCAACTATAAAATTATTGAGATTTTAGGTGCAGAAGGCGTTCAGTTTGCATATCCCGGCCAAAT
GGTTGTTGTCAAGCAAAAGCACGAAAGCGACCAATTCCAGGTGAATCTAAATAAAGAGGAAAAGGAACGGGCTTAA

Upstream 100 bases:

>100_bases
CGTTTCGCCGGGGTTTTGTGCTGCATAAGACATTTAAATGAACATCCTTACGAATATTTTAGTATAATAAACAATTGATT
GGGATAGAGGGGAGACAGTC

Downstream 100 bases:

>100_bases
AAGAGAGACTTCGTCTGACAGAGGCGGAGTCTTTTTCATGGTAAAATAAGAGAAAAAGGCGGTGTTGAGTTGGAAACATT
CAAAAGTATTCTACATGAAG

Product: integral inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MPDYLQQYFTLDNIIQIGISLAILLVFLILRKLFTRYFFNLLFNLTNRPKTEIFKQVVLAFDKPARWFFVALGLFLAIRY
SPFLDEQMPVISKIYRSLIVALLCWGLCNLTATSSFIFHKVNQRFELDMDDILAPFLSKLLRFVIIALSVSVIAQEFNYD
VNGFVAGLGLGGLAFALAAKDTISNFFGGIIIITEKPFTIGDWVETSTVTGSVEDITFRSTRFRTAQGALVTVPNSTLSM
EAITNWTRMTKRQITFSIHVSYATPIENLERSIHSLRTMLLEHEGVDNEIIMVNFDTFADSYYNLFFNFYTKTTVWAENL
NIREDINYKIIEILGAEGVQFAYPGQMVVVKQKHESDQFQVNLNKEEKERA

Sequences:

>Translated_371_residues
MPDYLQQYFTLDNIIQIGISLAILLVFLILRKLFTRYFFNLLFNLTNRPKTEIFKQVVLAFDKPARWFFVALGLFLAIRY
SPFLDEQMPVISKIYRSLIVALLCWGLCNLTATSSFIFHKVNQRFELDMDDILAPFLSKLLRFVIIALSVSVIAQEFNYD
VNGFVAGLGLGGLAFALAAKDTISNFFGGIIIITEKPFTIGDWVETSTVTGSVEDITFRSTRFRTAQGALVTVPNSTLSM
EAITNWTRMTKRQITFSIHVSYATPIENLERSIHSLRTMLLEHEGVDNEIIMVNFDTFADSYYNLFFNFYTKTTVWAENL
NIREDINYKIIEILGAEGVQFAYPGQMVVVKQKHESDQFQVNLNKEEKERA
>Mature_370_residues
PDYLQQYFTLDNIIQIGISLAILLVFLILRKLFTRYFFNLLFNLTNRPKTEIFKQVVLAFDKPARWFFVALGLFLAIRYS
PFLDEQMPVISKIYRSLIVALLCWGLCNLTATSSFIFHKVNQRFELDMDDILAPFLSKLLRFVIIALSVSVIAQEFNYDV
NGFVAGLGLGGLAFALAAKDTISNFFGGIIIITEKPFTIGDWVETSTVTGSVEDITFRSTRFRTAQGALVTVPNSTLSME
AITNWTRMTKRQITFSIHVSYATPIENLERSIHSLRTMLLEHEGVDNEIIMVNFDTFADSYYNLFFNFYTKTTVWAENLN
IREDINYKIIEILGAEGVQFAYPGQMVVVKQKHESDQFQVNLNKEEKERA

Specific function: May play a role in resistance to osmotic downshock

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family

Homologues:

Organism=Escherichia coli, GI1787591, Length=240, Percent_Identity=33.75, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789291, Length=234, Percent_Identity=27.3504273504274, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHDY_BACSU (O07594)

Other databases:

- EMBL:   Y14082
- EMBL:   AL009126
- PIR:   G69827
- RefSeq:   NP_388845.1
- ProteinModelPortal:   O07594
- SMR:   O07594
- EnsemblBacteria:   EBBACT00000003767
- GeneID:   939285
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU09640
- NMPDR:   fig|224308.1.peg.964
- GenoList:   BSU09640
- GeneTree:   EBGT00050000001807
- HOGENOM:   HBG710405
- OMA:   FRSTKIR
- PhylomeDB:   O07594
- ProtClustDB:   CLSK886972
- BioCyc:   BSUB:BSU09640-MONOMER
- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014

Pfam domain/function: PF00924 MS_channel; SSF82689 MscC_channel_C; SSF82861 MscS_transmembr; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 42538; Mature: 42407

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS01246 UPF0003

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd77343c)-; HASH(0xdee7d34)-; HASH(0xd4b0334)-; HASH(0xd9bc78c)-; HASH(0xe039ba8)-; HASH(0xd826688)-; HASH(0xe0dbae4)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDYLQQYFTLDNIIQIGISLAILLVFLILRKLFTRYFFNLLFNLTNRPKTEIFKQVVLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
FDKPARWFFVALGLFLAIRYSPFLDEQMPVISKIYRSLIVALLCWGLCNLTATSSFIFHK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNQRFELDMDDILAPFLSKLLRFVIIALSVSVIAQEFNYDVNGFVAGLGLGGLAFALAAK
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEECCCHHHHHHHHHHH
DTISNFFGGIIIITEKPFTIGDWVETSTVTGSVEDITFRSTRFRTAQGALVTVPNSTLSM
HHHHHHCCCEEEEECCCCCCCCCCCCCEECCCHHHEEEECCEEEECCCCEEEECCCCEEH
EAITNWTRMTKRQITFSIHVSYATPIENLERSIHSLRTMLLEHEGVDNEIIMVNFDTFAD
HHHHHHHHHHHHEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHH
SYYNLFFNFYTKTTVWAENLNIREDINYKIIEILGAEGVQFAYPGQMVVVKQKHESDQFQ
HHHHHHHHHHHHHEEEECCCCCCCCCCEEEEEEECCCCCEEECCCCEEEEEECCCCCCEE
VNLNKEEKERA
EECCHHHCCCH
>Mature Secondary Structure 
PDYLQQYFTLDNIIQIGISLAILLVFLILRKLFTRYFFNLLFNLTNRPKTEIFKQVVLA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
FDKPARWFFVALGLFLAIRYSPFLDEQMPVISKIYRSLIVALLCWGLCNLTATSSFIFHK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNQRFELDMDDILAPFLSKLLRFVIIALSVSVIAQEFNYDVNGFVAGLGLGGLAFALAAK
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEECCCHHHHHHHHHHH
DTISNFFGGIIIITEKPFTIGDWVETSTVTGSVEDITFRSTRFRTAQGALVTVPNSTLSM
HHHHHHCCCEEEEECCCCCCCCCCCCCEECCCHHHEEEECCEEEECCCCEEEECCCCEEH
EAITNWTRMTKRQITFSIHVSYATPIENLERSIHSLRTMLLEHEGVDNEIIMVNFDTFAD
HHHHHHHHHHHHEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHH
SYYNLFFNFYTKTTVWAENLNIREDINYKIIEILGAEGVQFAYPGQMVVVKQKHESDQFQ
HHHHHHHHHHHHHEEEECCCCCCCCCCEEEEEEECCCCCEEECCCCEEEEEECCCCCCEE
VNLNKEEKERA
EECCHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377