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The map label for this gene is perR

Identifier: 16077938

GI number: 16077938

Start: 944487

End: 944924

Strand: Direct

Name: perR

Synonym: BSU08730

Alternate gene names: 16077938

Gene position: 944487-944924 (Clockwise)

Preceding gene: 50812202

Following gene: 16077940

Centisome position: 22.4

GC content: 45.66

Gene sequence:

>438_bases
ATGGCTGCACATGAACTAAAAGAAGCCTTAGAAACGTTGAAGGAAACCGGAGTTCGCATTACTCCTCAACGTCATGCGAT
TCTGGAATATCTCGTTAACTCTATGGCTCATCCAACAGCGGACGATATATATAAAGCTCTGGAAGGGAAATTTCCTAACA
TGAGCGTAGCGACGGTATATAACAATTTGCGTGTGTTCCGGGAATCAGGTTTGGTAAAAGAGCTCACATACGGTGATGCT
TCCAGCAGATTCGATTTTGTCACATCCGATCACTATCACGCGATTTGCGAAAACTGCGGTAAAATTGTGGACTTCCACTA
CCCGGGCCTTGATGAAGTGGAGCAGCTCGCTGCCCACGTCACGGGCTTCAAGGTAAGCCACCACCGTTTAGAAATTTACG
GCGTCTGCCAAGAGTGTTCGAAAAAAGAAAATCATTAA

Upstream 100 bases:

>100_bases
TTTTACCCTGATATCAATTGACAAATTATCGTAGAAAGAGTTACACTAATTATAAACATTACAATGTAAGAATTTTTTTT
AGAAGAGAGGTGCATGACGG

Downstream 100 bases:

>100_bases
AAATAAGCTGACCGCACGAAACGGTCAGCTTATTTTATTTCGACATTTTCTTTTTATTATAAGACTCATCAAATTCTTTT
CCTTCTAATCCCTTATCTAA

Product: Fur family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 144

Protein sequence:

>145_residues
MAAHELKEALETLKETGVRITPQRHAILEYLVNSMAHPTADDIYKALEGKFPNMSVATVYNNLRVFRESGLVKELTYGDA
SSRFDFVTSDHYHAICENCGKIVDFHYPGLDEVEQLAAHVTGFKVSHHRLEIYGVCQECSKKENH

Sequences:

>Translated_145_residues
MAAHELKEALETLKETGVRITPQRHAILEYLVNSMAHPTADDIYKALEGKFPNMSVATVYNNLRVFRESGLVKELTYGDA
SSRFDFVTSDHYHAICENCGKIVDFHYPGLDEVEQLAAHVTGFKVSHHRLEIYGVCQECSKKENH
>Mature_144_residues
AAHELKEALETLKETGVRITPQRHAILEYLVNSMAHPTADDIYKALEGKFPNMSVATVYNNLRVFRESGLVKELTYGDAS
SRFDFVTSDHYHAICENCGKIVDFHYPGLDEVEQLAAHVTGFKVSHHRLEIYGVCQECSKKENH

Specific function: Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA, ahpC, ahpF, the heme biosynthesis operon (hemAXCDBL), fur, perR, zosA and mrgA

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family

Homologues:

Organism=Escherichia coli, GI1786899, Length=134, Percent_Identity=31.3432835820896, Blast_Score=71, Evalue=4e-14,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): PERR_BACSU (P71086)

Other databases:

- EMBL:   Z82044
- EMBL:   AL009126
- PIR:   B69816
- RefSeq:   NP_388753.1
- PDB:   2FE3
- PDB:   2RGV
- PDB:   3F8N
- PDBsum:   2FE3
- PDBsum:   2RGV
- PDBsum:   3F8N
- ProteinModelPortal:   P71086
- SMR:   P71086
- EnsemblBacteria:   EBBACT00000000843
- GeneID:   939227
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU08730
- NMPDR:   fig|224308.1.peg.872
- GenoList:   BSU08730
- GeneTree:   EBGT00050000001212
- HOGENOM:   HBG731501
- OMA:   NHYHVIC
- PhylomeDB:   P71086
- ProtClustDB:   CLSK2460900
- BioCyc:   BSUB:BSU08730-MONOMER
- GO:   GO:0005737
- InterPro:   IPR002481
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10

Pfam domain/function: PF01475 FUR

EC number: NA

Molecular weight: Translated: 16424; Mature: 16293

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAHELKEALETLKETGVRITPQRHAILEYLVNSMAHPTADDIYKALEGKFPNMSVATVY
CCHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHH
NNLRVFRESGLVKELTYGDASSRFDFVTSDHYHAICENCGKIVDFHYPGLDEVEQLAAHV
HHHHHHHHCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHCCEEECCCCCHHHHHHHHHHH
TGFKVSHHRLEIYGVCQECSKKENH
HCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AAHELKEALETLKETGVRITPQRHAILEYLVNSMAHPTADDIYKALEGKFPNMSVATVY
CHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHH
NNLRVFRESGLVKELTYGDASSRFDFVTSDHYHAICENCGKIVDFHYPGLDEVEQLAAHV
HHHHHHHHCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHCCEEECCCCCHHHHHHHHHHH
TGFKVSHHRLEIYGVCQECSKKENH
HCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202460; 9384377; 9701813; 12100544