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The map label for this gene is yfhP

Identifier: 16077928

GI number: 16077928

Start: 934457

End: 935440

Strand: Reverse

Name: yfhP

Synonym: BSU08620

Alternate gene names: 16077928

Gene position: 935440-934457 (Counterclockwise)

Preceding gene: 16077930

Following gene: 50812199

Centisome position: 22.19

GC content: 45.33

Gene sequence:

>984_bases
ATGGATACGGGCACACATGTCGTTATGGGCATCGCACTGGGCGGTATTGCGACGCTTGATCCTGTTGTCGGATCAGATCC
GGCAATGGCTCACGCTGTTATGATCGCAACGCTTGCGGGCTCTCAGGCTCCGGATATTGATACTGTGTTAAAGCTTAAAA
ACAATGCTGTTTATATAAGGAATCACAGAGGATTTACCCATTCAATTCCCGCCGTTTTGTTTTGGTCTGTCATCATCCCG
GCGATTCTGTATTTATTTTATCCTCAGGCCGATTTTCTGCACCTGTGGCTGTGGACACTGCTGGCAGTCGTTCTGCATGT
CTTTGTTGATATATTCAACGCCTATGGAACACAAGCCATTCGTCCGTTTTCGAAAAAATGGGTTGCGCTCGGGCTGATTA
ATACGTTTGATCCGTTTATTTTTATCAGCCATCTGGCAGCTATCGCGATTTGGTATGCAGGCGGGAGTCCCGGCATCACG
TTTCTCAGCTTATATATCATATTGGTAGGCTACTACTTGGTGCGCCTGATCATGCAGCTGAGAATTAAACGGAAGCTTCA
TGAGATGATTCATGATGAGATCGAAAGCATTATTATTTCTCCAACGATGAAATTCAGGCAATGGCGAATCGCAGTGACGA
CAGCACATGCTTTCTATGTAGGAAGAAGCATGGAAGGACATGTCGTGATTCTGGATACATTTAATCGGGTGCCTGTTCCT
GAAACCGATGTAATGCATGCGGCAAAGCAGGATGATAACATCGCGGCGTTTCTGTCCTTTTCTCCGGTATACCGGTGGGA
AGTGGATACGTTTAAAGATCATTATGAGGTGAGATTTATCGACCTGCGTTATCGGAGCAAAGGCCATTATCCGTTTGTCG
CAATTGTTCATATCGGCCATGATCTCACGATTCGTTCATCCTATACGGGATGGATATTCAGCGAAGAAAAACTTCAGAAA
AAATTAAAGCTCGGCTCTATATAG

Upstream 100 bases:

>100_bases
ACATATGAGAACGATTGAATCAGTTTAAAAATTGGGTATATGAAAATGGGGAATTTCTTACAAAGTGAATGTGCAGGATC
ACCCTGCAAGGAGGTCACCT

Downstream 100 bases:

>100_bases
AGCCGGGCTTTTTACGTCTTATATAAAAAACAGCAAGCAGCAGACTGACGAGAGATATGATCGCCGATATTTTGAAGTAT
GGCGGATAGTAAGTCAGCTC

Product: membrane hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MDTGTHVVMGIALGGIATLDPVVGSDPAMAHAVMIATLAGSQAPDIDTVLKLKNNAVYIRNHRGFTHSIPAVLFWSVIIP
AILYLFYPQADFLHLWLWTLLAVVLHVFVDIFNAYGTQAIRPFSKKWVALGLINTFDPFIFISHLAAIAIWYAGGSPGIT
FLSLYIILVGYYLVRLIMQLRIKRKLHEMIHDEIESIIISPTMKFRQWRIAVTTAHAFYVGRSMEGHVVILDTFNRVPVP
ETDVMHAAKQDDNIAAFLSFSPVYRWEVDTFKDHYEVRFIDLRYRSKGHYPFVAIVHIGHDLTIRSSYTGWIFSEEKLQK
KLKLGSI

Sequences:

>Translated_327_residues
MDTGTHVVMGIALGGIATLDPVVGSDPAMAHAVMIATLAGSQAPDIDTVLKLKNNAVYIRNHRGFTHSIPAVLFWSVIIP
AILYLFYPQADFLHLWLWTLLAVVLHVFVDIFNAYGTQAIRPFSKKWVALGLINTFDPFIFISHLAAIAIWYAGGSPGIT
FLSLYIILVGYYLVRLIMQLRIKRKLHEMIHDEIESIIISPTMKFRQWRIAVTTAHAFYVGRSMEGHVVILDTFNRVPVP
ETDVMHAAKQDDNIAAFLSFSPVYRWEVDTFKDHYEVRFIDLRYRSKGHYPFVAIVHIGHDLTIRSSYTGWIFSEEKLQK
KLKLGSI
>Mature_327_residues
MDTGTHVVMGIALGGIATLDPVVGSDPAMAHAVMIATLAGSQAPDIDTVLKLKNNAVYIRNHRGFTHSIPAVLFWSVIIP
AILYLFYPQADFLHLWLWTLLAVVLHVFVDIFNAYGTQAIRPFSKKWVALGLINTFDPFIFISHLAAIAIWYAGGSPGIT
FLSLYIILVGYYLVRLIMQLRIKRKLHEMIHDEIESIIISPTMKFRQWRIAVTTAHAFYVGRSMEGHVVILDTFNRVPVP
ETDVMHAAKQDDNIAAFLSFSPVYRWEVDTFKDHYEVRFIDLRYRSKGHYPFVAIVHIGHDLTIRSSYTGWIFSEEKLQK
KLKLGSI

Specific function: May act as a negative regulator for the transcription of yfhQ, fabL, sspE and yfhP

COG id: COG1988

COG function: function code R; Predicted membrane-bound metal-dependent hydrolases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YFHP_BACSU (O31583)

Other databases:

- EMBL:   D85082
- EMBL:   AL009126
- PIR:   H69801
- RefSeq:   NP_388742.1
- EnsemblBacteria:   EBBACT00000002707
- GeneID:   936190
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU08620
- NMPDR:   fig|224308.1.peg.861
- GenoList:   BSU08620
- GeneTree:   EBGT00050000000836
- HOGENOM:   HBG313989
- OMA:   LRYRSKG
- ProtClustDB:   CLSK872872
- BioCyc:   BSUB:BSU08620-MONOMER
- InterPro:   IPR007404

Pfam domain/function: PF04307 DUF457

EC number: NA

Molecular weight: Translated: 37128; Mature: 37128

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xdae6944)-; HASH(0xb115154)-; HASH(0xdad8788)-; HASH(0xd7ad990)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTGTHVVMGIALGGIATLDPVVGSDPAMAHAVMIATLAGSQAPDIDTVLKLKNNAVYIR
CCCCCEEEEEEHHCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHEEECCCEEEEE
NHRGFTHSIPAVLFWSVIIPAILYLFYPQADFLHLWLWTLLAVVLHVFVDIFNAYGTQAI
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RPFSKKWVALGLINTFDPFIFISHLAAIAIWYAGGSPGITFLSLYIILVGYYLVRLIMQL
CHHHHHHEEEEHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
RIKRKLHEMIHDEIESIIISPTMKFRQWRIAVTTAHAFYVGRSMEGHVVILDTFNRVPVP
HHHHHHHHHHHHHHHHEEECCCHHHEEEEEEEEEEEEEEECCCCCCCEEEEECCCCCCCC
ETDVMHAAKQDDNIAAFLSFSPVYRWEVDTFKDHYEVRFIDLRYRSKGHYPFVAIVHIGH
CHHHHHHHCCCCCEEEEEEECCEEEEECCCCCCCEEEEEEEEEECCCCCCCEEEEEEECC
DLTIRSSYTGWIFSEEKLQKKLKLGSI
CEEEECCCCCEEECHHHHHHHHCCCCH
>Mature Secondary Structure
MDTGTHVVMGIALGGIATLDPVVGSDPAMAHAVMIATLAGSQAPDIDTVLKLKNNAVYIR
CCCCCEEEEEEHHCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHEEECCCEEEEE
NHRGFTHSIPAVLFWSVIIPAILYLFYPQADFLHLWLWTLLAVVLHVFVDIFNAYGTQAI
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RPFSKKWVALGLINTFDPFIFISHLAAIAIWYAGGSPGITFLSLYIILVGYYLVRLIMQL
CHHHHHHEEEEHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
RIKRKLHEMIHDEIESIIISPTMKFRQWRIAVTTAHAFYVGRSMEGHVVILDTFNRVPVP
HHHHHHHHHHHHHHHHEEECCCHHHEEEEEEEEEEEEEEECCCCCCCEEEEECCCCCCCC
ETDVMHAAKQDDNIAAFLSFSPVYRWEVDTFKDHYEVRFIDLRYRSKGHYPFVAIVHIGH
CHHHHHHHCCCCCEEEEEEECCEEEEECCCCCCCEEEEEEEEEECCCCCCCEEEEEEECC
DLTIRSSYTGWIFSEEKLQKKLKLGSI
CEEEECCCCCEEECHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377