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The map label for this gene is citM

Identifier: 16077828

GI number: 16077828

Start: 834383

End: 835684

Strand: Direct

Name: citM

Synonym: BSU07610

Alternate gene names: 16077828

Gene position: 834383-835684 (Clockwise)

Preceding gene: 255767186

Following gene: 16077829

Centisome position: 19.79

GC content: 48.16

Gene sequence:

>1302_bases
GTGTTAGCAATCTTAGGCTTTCTCATGATGCTTGTGTTTATGGCATTGATCATGACAAAACGGCTTTCTGTTTTAACAGC
ATTAGTTTTGACGCCGATTGTGTTTGCGCTTATCGCCGGATTTGGATTTACTGAAGTTGGGGACATGATGATTTCGGGGA
TTCAGCAAGTCGCGCCGACTGCGGTCATGATTATGTTTGCGATCTTATATTTTGGAATTATGATTGATACAGGCCTGTTT
GATCCAATGGTTGGCAAAATTTTAAGCATGGTCAAAGGAGACCCTTTAAAAATTGTTGTCGGGACAGCGGTTCTTACAAT
GCTCGTCGCCTTGGACGGAGATGGCTCGACAACGTACATGATTACGACAAGCGCCATGCTTCCGCTCTATTTGCTGCTAG
GCATCCGGCCAATTATCTTGGCAGGAATCGCGGGAGTCGGCATGGGAATCATGAACACGATTCCATGGGGAGGTGCGACG
CCGAGGGCGGCGAGTGCGCTGGGGGTTGATCCAGCTGAGCTTACAGGGCCGATGATTCCTGTCATTGCAAGCGGGATGCT
TTGTATGGTGGCAGTTGCGTATGTGCTTGGAAAAGCGGAACGAAAGCGCCTTGGTGTGATTGAACTGAAACAGCCAGCCA
ATGCCAATGAACCGGCTGCTGCGGTTGAAGATGAGTGGAAGCGGCCGAAGCTTTGGTGGTTCAATTTATTGTTAACGCTT
TCTTTAATAGGATGTTTAGTATCGGGTAAAGTCAGTTTAACCGTACTGTTTGTCATTGCGTTTTGTATTGCGCTGATTGT
GAATTATCCCAATCTCGAGCATCAGAGACAGCGCATCGCGGCGCATTCCAGCAACGTGCTGGCTATCGGTTCAATGATTT
TTGCTGCGGGGGTGTTCACGGGGATTTTGACAGGCACGAAAATGGTTGATGAAATGGCGATCTCGCTCGTGTCCATGATA
CCGGAACAAATGGGCGGATTGATCCCGGCGATTGTTGCCTTAACAAGCGGCATTTTCACATTTTTGATGCCGAATGACGC
GTATTTCTACGGGGTGCTGCCGATTTTATCAGAAACAGCTGTCGCATACGGTGTGGATAAAGTGGAAATTGCCAGAGCCT
CTATTATCGGCCAGCCGATTCATATGCTGAGTCCGCTTGTGCCATCCACTCATTTGCTTGTCGGACTCGTCGGAGTTTCT
ATTGATGACCATCAAAAATTCGCATTGAAATGGGCGGTTCTCGCAGTGATCGTCATGACGGCTATCGCTCTATTGATCGG
TGCGATCTCTATTTCCGTATGA

Upstream 100 bases:

>100_bases
TACTTGCGGTTGGTTTTCCCATACGATGGCAAAAAGGCAAGACAAAAAGGGGAGTAAGGGAGAAAAAAATGTAAGCGGAT
TCATTTAAGGGGGAATGGAT

Downstream 100 bases:

>100_bases
TAATTCAGGCGTAATGACACACACTAACGGCATACAACATTCCGGAGGTGTCATTATGAGTGATCCTTATATGCCGCTGA
CTTCAGTCAGAAGCGGAGCG

Product: transporter of divalent metal ions/citrate complexes

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MLAILGFLMMLVFMALIMTKRLSVLTALVLTPIVFALIAGFGFTEVGDMMISGIQQVAPTAVMIMFAILYFGIMIDTGLF
DPMVGKILSMVKGDPLKIVVGTAVLTMLVALDGDGSTTYMITTSAMLPLYLLLGIRPIILAGIAGVGMGIMNTIPWGGAT
PRAASALGVDPAELTGPMIPVIASGMLCMVAVAYVLGKAERKRLGVIELKQPANANEPAAAVEDEWKRPKLWWFNLLLTL
SLIGCLVSGKVSLTVLFVIAFCIALIVNYPNLEHQRQRIAAHSSNVLAIGSMIFAAGVFTGILTGTKMVDEMAISLVSMI
PEQMGGLIPAIVALTSGIFTFLMPNDAYFYGVLPILSETAVAYGVDKVEIARASIIGQPIHMLSPLVPSTHLLVGLVGVS
IDDHQKFALKWAVLAVIVMTAIALLIGAISISV

Sequences:

>Translated_433_residues
MLAILGFLMMLVFMALIMTKRLSVLTALVLTPIVFALIAGFGFTEVGDMMISGIQQVAPTAVMIMFAILYFGIMIDTGLF
DPMVGKILSMVKGDPLKIVVGTAVLTMLVALDGDGSTTYMITTSAMLPLYLLLGIRPIILAGIAGVGMGIMNTIPWGGAT
PRAASALGVDPAELTGPMIPVIASGMLCMVAVAYVLGKAERKRLGVIELKQPANANEPAAAVEDEWKRPKLWWFNLLLTL
SLIGCLVSGKVSLTVLFVIAFCIALIVNYPNLEHQRQRIAAHSSNVLAIGSMIFAAGVFTGILTGTKMVDEMAISLVSMI
PEQMGGLIPAIVALTSGIFTFLMPNDAYFYGVLPILSETAVAYGVDKVEIARASIIGQPIHMLSPLVPSTHLLVGLVGVS
IDDHQKFALKWAVLAVIVMTAIALLIGAISISV
>Mature_433_residues
MLAILGFLMMLVFMALIMTKRLSVLTALVLTPIVFALIAGFGFTEVGDMMISGIQQVAPTAVMIMFAILYFGIMIDTGLF
DPMVGKILSMVKGDPLKIVVGTAVLTMLVALDGDGSTTYMITTSAMLPLYLLLGIRPIILAGIAGVGMGIMNTIPWGGAT
PRAASALGVDPAELTGPMIPVIASGMLCMVAVAYVLGKAERKRLGVIELKQPANANEPAAAVEDEWKRPKLWWFNLLLTL
SLIGCLVSGKVSLTVLFVIAFCIALIVNYPNLEHQRQRIAAHSSNVLAIGSMIFAAGVFTGILTGTKMVDEMAISLVSMI
PEQMGGLIPAIVALTSGIFTFLMPNDAYFYGVLPILSETAVAYGVDKVEIARASIIGQPIHMLSPLVPSTHLLVGLVGVS
IDDHQKFALKWAVLAVIVMTAIALLIGAISISV

Specific function: Proton motive force-driven secondary transporter that mediates the transport of citrate complexed to Mg(2+). Cotransports at least two protons per Mg(2+)-citrate complex. Can also transport citrate in complex with Ni(2+), Mn(2+), Co(2+), and Zn(2+)

COG id: COG2851

COG function: function code C; H+/citrate symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CITM_BACSU (P55069)

Other databases:

- EMBL:   U62003
- EMBL:   D86417
- EMBL:   AL009126
- PIR:   C69600
- RefSeq:   NP_388642.1
- ProteinModelPortal:   P55069
- EnsemblBacteria:   EBBACT00000001458
- GeneID:   938801
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU07610
- NMPDR:   fig|224308.1.peg.761
- GenoList:   BSU07610
- GeneTree:   EBGT00050000001369
- HOGENOM:   HBG297065
- OMA:   DEMAISL
- ProtClustDB:   CLSK886858
- BioCyc:   BSUB:BSU07610-MONOMER
- InterPro:   IPR014738
- InterPro:   IPR004680
- PANTHER:   PTHR10283:SF44
- TIGRFAMs:   TIGR00784

Pfam domain/function: PF03600 CitMHS

EC number: NA

Molecular weight: Translated: 45831; Mature: 45831

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd6a15b8)-; HASH(0xdaa6d50)-; HASH(0xd0644c4)-; HASH(0xb661d64)-; HASH(0xd7f0304)-; HASH(0xd88790c)-; HASH(0xd4f3b94)-; HASH(0xb571930)-; HASH(0xc435c7c)-; HASH(0xcdfb098)-; HASH(0xbfe38ac)-; HASH(0xdda2798)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAILGFLMMLVFMALIMTKRLSVLTALVLTPIVFALIAGFGFTEVGDMMISGIQQVAPT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AVMIMFAILYFGIMIDTGLFDPMVGKILSMVKGDPLKIVVGTAVLTMLVALDGDGSTTYM
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCCEEEE
ITTSAMLPLYLLLGIRPIILAGIAGVGMGIMNTIPWGGATPRAASALGVDPAELTGPMIP
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHCCCHHH
VIASGMLCMVAVAYVLGKAERKRLGVIELKQPANANEPAAAVEDEWKRPKLWWFNLLLTL
HHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHCCCCHHHHHHHHHHH
SLIGCLVSGKVSLTVLFVIAFCIALIVNYPNLEHQRQRIAAHSSNVLAIGSMIFAAGVFT
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
GILTGTKMVDEMAISLVSMIPEQMGGLIPAIVALTSGIFTFLMPNDAYFYGVLPILSETA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHH
VAYGVDKVEIARASIIGQPIHMLSPLVPSTHLLVGLVGVSIDDHQKFALKWAVLAVIVMT
HHHCCCHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AIALLIGAISISV
HHHHHHHHHHHCH
>Mature Secondary Structure
MLAILGFLMMLVFMALIMTKRLSVLTALVLTPIVFALIAGFGFTEVGDMMISGIQQVAPT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AVMIMFAILYFGIMIDTGLFDPMVGKILSMVKGDPLKIVVGTAVLTMLVALDGDGSTTYM
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCCEEEE
ITTSAMLPLYLLLGIRPIILAGIAGVGMGIMNTIPWGGATPRAASALGVDPAELTGPMIP
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHCCCHHH
VIASGMLCMVAVAYVLGKAERKRLGVIELKQPANANEPAAAVEDEWKRPKLWWFNLLLTL
HHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHCCCCHHHHHHHHHHH
SLIGCLVSGKVSLTVLFVIAFCIALIVNYPNLEHQRQRIAAHSSNVLAIGSMIFAAGVFT
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
GILTGTKMVDEMAISLVSMIPEQMGGLIPAIVALTSGIFTFLMPNDAYFYGVLPILSETA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHH
VAYGVDKVEIARASIIGQPIHMLSPLVPSTHLLVGLVGVSIDDHQKFALKWAVLAVIVMT
HHHCCCHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AIALLIGAISISV
HHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8892821; 9272861; 9384377; 11029430; 10972810; 11053381; 11891560