BacMap

Definition	Bacillus subtilis subsp. subtilis str. 168 chromosome, complete genome.
Accession	NC_000964
Length	4,215,606

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The map label for this gene is yclH

Identifier: 16077441

GI number: 16077441

Start: 424208

End: 424888

Strand: Reverse

Name: yclH

Synonym: BSU03730

Alternate gene names: 16077441

Gene position: 424888-424208 (Counterclockwise)

Preceding gene: 255767117

Following gene: 16077437

Centisome position: 10.08

GC content: 44.05

Gene sequence:

>681_bases
ATGAGCTTATTACAATTTCAACAAGTCGGCTACTGGTATAAAAACAAAAGCCAGCCATTGTTTCAGGATATTAACATCAG
CTTTCAAAAAGGAAAATTCTACACAATCGTCGGAACATCAGGGACGGGGAAAACCACTTTCCTGTCTCTGGCAGGCGGAC
TTGACGCACCAAAAGAAGGAAACATCCTTTACGACGGAAAAGCGGTTTCTAAAATCGGCTTAACCAATTTCAGAAATCAA
TATGTATCAATCGTCTTTCAGGCGTACAACCTGCTCCCGTATATGACGGCTTTGCAGAACGTCACAACCGCTATGGAAAT
CACAGGTTCTAAAGAAAAGAACAAAGAATCATATGCGCTTGACATGCTGCAGAAGGTTGGCATCAACGAAAAACAAGCCC
GGCAAAAAGTGCTCACACTGAGCGGCGGACAGCAGCAGCGGGTATCAATTACAAGGGCTTTCTGCTGTGACACGGATCTT
ATCGTAGCCGATGAACCGACCGGAAACCTTGATGAGGACACATCAAAAGAGATCGTACGGCTCTTTCAGGATCTGGCGCA
CAAGGAAGATAAATGCGTCATTATGGTGACGCACGATGAACAAATTGCAAAAGTGTCAGACATCAATATCAGACTTTCAA
GAGGAAGTTTTACTGTGAAGGAAAACGTCGCAGTCGTATAA

Upstream 100 bases:

>100_bases
CCTAATCGCAATCATTGCAACATTGCTGCCGTCAATTTCAGTACTGCGGCTTCATCCGAAAACGATATTGACAAAACAGG
AATAGAAAGAGGCGGAACCT

Downstream 100 bases:

>100_bases
CAAAACGCGCCTCTGCCAGTGCAGACAGGGGCGCACCCTATATCCCCCTTTTATATAGAAGTGAACATAAAAAGAGCGGC
GGCCGCATCCCCCCGCTCTT

Product: ABC transporter ATPase component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MSLLQFQQVGYWYKNKSQPLFQDINISFQKGKFYTIVGTSGTGKTTFLSLAGGLDAPKEGNILYDGKAVSKIGLTNFRNQ
YVSIVFQAYNLLPYMTALQNVTTAMEITGSKEKNKESYALDMLQKVGINEKQARQKVLTLSGGQQQRVSITRAFCCDTDL
IVADEPTGNLDEDTSKEIVRLFQDLAHKEDKCVIMVTHDEQIAKVSDINIRLSRGSFTVKENVAVV

Sequences:

>Translated_226_residues
MSLLQFQQVGYWYKNKSQPLFQDINISFQKGKFYTIVGTSGTGKTTFLSLAGGLDAPKEGNILYDGKAVSKIGLTNFRNQ
YVSIVFQAYNLLPYMTALQNVTTAMEITGSKEKNKESYALDMLQKVGINEKQARQKVLTLSGGQQQRVSITRAFCCDTDL
IVADEPTGNLDEDTSKEIVRLFQDLAHKEDKCVIMVTHDEQIAKVSDINIRLSRGSFTVKENVAVV
>Mature_225_residues
SLLQFQQVGYWYKNKSQPLFQDINISFQKGKFYTIVGTSGTGKTTFLSLAGGLDAPKEGNILYDGKAVSKIGLTNFRNQY
VSIVFQAYNLLPYMTALQNVTTAMEITGSKEKNKESYALDMLQKVGINEKQARQKVLTLSGGQQQRVSITRAFCCDTDLI
VADEPTGNLDEDTSKEIVRLFQDLAHKEDKCVIMVTHDEQIAKVSDINIRLSRGSFTVKENVAVV

Specific function: Part Of The Abc Transporter Complex Lolcde Involved In The Translocation Of Mature Outer Membrane-Directed Lipoproteins, From The Inner Membrane To The Periplasmic Chaperone, Lola. Responsible For The Formation Of The Lola-Lipoprotein Complex In An ATP-De

COG id: COG1136

COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain

Homologues:

Organism=Homo sapiens, GI105990541, Length=186, Percent_Identity=26.8817204301075, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI148612844, Length=227, Percent_Identity=28.6343612334802, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI255708477, Length=227, Percent_Identity=28.6343612334802, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI171184400, Length=226, Percent_Identity=28.7610619469027, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI21536376, Length=193, Percent_Identity=25.3886010362694, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI42741659, Length=214, Percent_Identity=27.5700934579439, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI9961252, Length=214, Percent_Identity=28.0373831775701, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI9961250, Length=214, Percent_Identity=28.0373831775701, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI4505771, Length=214, Percent_Identity=28.0373831775701, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI31657092, Length=210, Percent_Identity=26.1904761904762, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI215820660, Length=177, Percent_Identity=29.3785310734463, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI20143975, Length=177, Percent_Identity=29.3785310734463, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI116734710, Length=186, Percent_Identity=27.4193548387097, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI150417984, Length=186, Percent_Identity=27.4193548387097, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI9665248, Length=226, Percent_Identity=24.7787610619469, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI42490749, Length=197, Percent_Identity=27.9187817258883, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87081834, Length=223, Percent_Identity=35.8744394618834, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI1786703, Length=197, Percent_Identity=34.010152284264, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1787105, Length=199, Percent_Identity=34.1708542713568, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1787029, Length=199, Percent_Identity=32.1608040201005, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786563, Length=220, Percent_Identity=31.8181818181818, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789032, Length=181, Percent_Identity=32.5966850828729, Blast_Score=113, Evalue=8e-27,
Organism=Escherichia coli, GI1789873, Length=201, Percent_Identity=34.3283582089552, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789672, Length=224, Percent_Identity=32.1428571428571, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788761, Length=206, Percent_Identity=32.5242718446602, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI87081709, Length=203, Percent_Identity=32.512315270936, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1786398, Length=210, Percent_Identity=28.5714285714286, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1788225, Length=211, Percent_Identity=32.7014218009479, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788644, Length=186, Percent_Identity=35.4838709677419, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1787370, Length=180, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87081791, Length=197, Percent_Identity=30.9644670050761, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1786872, Length=205, Percent_Identity=31.7073170731707, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1787712, Length=177, Percent_Identity=33.8983050847458, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1787089, Length=208, Percent_Identity=31.7307692307692, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1788450, Length=201, Percent_Identity=27.363184079602, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082267, Length=205, Percent_Identity=30.2439024390244, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789963, Length=215, Percent_Identity=30.6976744186047, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1787143, Length=197, Percent_Identity=32.48730964467, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790467, Length=186, Percent_Identity=30.1075268817204, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1789891, Length=219, Percent_Identity=27.3972602739726, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1789962, Length=182, Percent_Identity=31.3186813186813, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786698, Length=199, Percent_Identity=29.1457286432161, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1787164, Length=180, Percent_Identity=31.1111111111111, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI48994883, Length=189, Percent_Identity=31.7460317460317, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1788506, Length=190, Percent_Identity=28.9473684210526, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789890, Length=204, Percent_Identity=32.3529411764706, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1786253, Length=214, Percent_Identity=25.7009345794392, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790544, Length=203, Percent_Identity=29.5566502463054, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790534, Length=191, Percent_Identity=27.2251308900524, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1789586, Length=211, Percent_Identity=31.2796208530806, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI48994997, Length=192, Percent_Identity=28.125, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787758, Length=184, Percent_Identity=27.1739130434783, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1787500, Length=204, Percent_Identity=26.9607843137255, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1787547, Length=219, Percent_Identity=22.8310502283105, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787112, Length=208, Percent_Identity=29.3269230769231, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI48995001, Length=203, Percent_Identity=28.0788177339901, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788210, Length=209, Percent_Identity=26.7942583732057, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788897, Length=211, Percent_Identity=21.8009478672986, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786345, Length=204, Percent_Identity=25.9803921568627, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790162, Length=221, Percent_Identity=28.0542986425339, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786319, Length=199, Percent_Identity=28.643216080402, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787759, Length=198, Percent_Identity=29.2929292929293, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789864, Length=201, Percent_Identity=23.3830845771144, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788540, Length=195, Percent_Identity=25.6410256410256, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI145693107, Length=208, Percent_Identity=27.4038461538462, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788165, Length=202, Percent_Identity=28.2178217821782, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1790525, Length=199, Percent_Identity=25.1256281407035, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1790190, Length=199, Percent_Identity=25.6281407035176, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788472, Length=222, Percent_Identity=27.027027027027, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786653, Length=195, Percent_Identity=24.1025641025641, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786803, Length=195, Percent_Identity=27.6923076923077, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789991, Length=226, Percent_Identity=22.5663716814159, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI87082268, Length=222, Percent_Identity=24.7747747747748, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1790739, Length=185, Percent_Identity=23.7837837837838, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=223, Percent_Identity=27.8026905829596, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71992290, Length=224, Percent_Identity=25.4464285714286, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17533971, Length=202, Percent_Identity=27.2277227722772, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17565938, Length=218, Percent_Identity=25.6880733944954, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17543740, Length=202, Percent_Identity=26.2376237623762, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115533608, Length=195, Percent_Identity=28.2051282051282, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71996550, Length=211, Percent_Identity=27.0142180094787, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17558664, Length=209, Percent_Identity=25.8373205741627, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71992285, Length=211, Percent_Identity=25.5924170616114, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17559834, Length=191, Percent_Identity=28.2722513089005, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193202349, Length=213, Percent_Identity=27.6995305164319, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71984940, Length=201, Percent_Identity=26.865671641791, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6324985, Length=202, Percent_Identity=26.7326732673267, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324498, Length=202, Percent_Identity=22.7722772277228, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24582014, Length=219, Percent_Identity=29.2237442922374, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24582012, Length=219, Percent_Identity=29.2237442922374, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24666092, Length=184, Percent_Identity=27.1739130434783, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI85726357, Length=216, Percent_Identity=28.2407407407407, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI28574150, Length=183, Percent_Identity=24.5901639344262, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI116007328, Length=183, Percent_Identity=24.5901639344262, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641565, Length=217, Percent_Identity=23.5023041474654, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24581387, Length=204, Percent_Identity=29.9019607843137, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581383, Length=204, Percent_Identity=29.9019607843137, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24581385, Length=204, Percent_Identity=29.9019607843137, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YCLH_BACSU (P94411)

Other databases:

- EMBL:   D50453
- EMBL:   AL009126
- PIR:   E69762
- RefSeq:   NP_388255.1
- ProteinModelPortal:   P94411
- SMR:   P94411
- EnsemblBacteria:   EBBACT00000002395
- GeneID:   938289
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU03730
- NMPDR:   fig|224308.1.peg.374
- GenoList:   BSU03730
- GeneTree:   EBGT00070000032192
- HOGENOM:   HBG758042
- OMA:   VSDINIR
- ProtClustDB:   CLSK886693
- BioCyc:   BSUB:BSU03730-MONOMER
- GO:   GO:0006810
- InterPro:   IPR003439
- InterPro:   IPR003593
- SMART:   SM00382

Pfam domain/function: PF00005 ABC_tran

EC number: NA

Molecular weight: Translated: 25209; Mature: 25078

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLQFQQVGYWYKNKSQPLFQDINISFQKGKFYTIVGTSGTGKTTFLSLAGGLDAPKEG
CCCHHHHHHCCEECCCCCCCEEECCEEEECCEEEEEEECCCCCCEEEEEEECCCCCCCCC
NILYDGKAVSKIGLTNFRNQYVSIVFQAYNLLPYMTALQNVTTAMEITGSKEKNKESYAL
CEEECCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHH
DMLQKVGINEKQARQKVLTLSGGQQQRVSITRAFCCDTDLIVADEPTGNLDEDTSKEIVR
HHHHHCCCCHHHHHHEEEEECCCCCHHHEEEEHEECCCCEEEECCCCCCCCCCHHHHHHH
LFQDLAHKEDKCVIMVTHDEQIAKVSDINIRLSRGSFTVKENVAVV
HHHHHHCCCCCEEEEEECCCHHEEEECEEEEEECCCEEEECCEEEC
>Mature Secondary Structure 
SLLQFQQVGYWYKNKSQPLFQDINISFQKGKFYTIVGTSGTGKTTFLSLAGGLDAPKEG
CCHHHHHHCCEECCCCCCCEEECCEEEECCEEEEEEECCCCCCEEEEEEECCCCCCCCC
NILYDGKAVSKIGLTNFRNQYVSIVFQAYNLLPYMTALQNVTTAMEITGSKEKNKESYAL
CEEECCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHH
DMLQKVGINEKQARQKVLTLSGGQQQRVSITRAFCCDTDLIVADEPTGNLDEDTSKEIVR
HHHHHCCCCHHHHHHEEEEECCCCCHHHEEEEHEECCCCEEEECCCCCCCCCCHHHHHHH
LFQDLAHKEDKCVIMVTHDEQIAKVSDINIRLSRGSFTVKENVAVV
HHHHHHCCCCCEEEEEECCCHHEEEECEEEEEECCCEEEECCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377