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The map label for this gene is nuoH [H]

Identifier: 159901496

GI number: 159901496

Start: 6320666

End: 6321907

Strand: Direct

Name: nuoH [H]

Synonym: Haur_4985

Alternate gene names: 159901496

Gene position: 6320666-6321907 (Clockwise)

Preceding gene: 159901495

Following gene: 159901497

Centisome position: 99.59

GC content: 52.33

Gene sequence:

>1242_bases
ATGGCTGATGCACTAACACAACTAGGCTTTGCATCATGGCTGAGTGTTCTGATTGCCAGCATCATTAAAGTAACCCTCAT
TCTCGTGGGCGGTTCGGTTGGCATGATGTTCCTGACGTGGTATGAACGCCGCGCTATTTCGTATATGCAAGACCGCCGCG
GCCCCAACCGCGTTGGTCCTCAAGGGTTGTTGCAACCAATTTCCGAAGCGATCAAAACGATGACCAAGGAAGATGCAACG
CCCCGTGAAGCAGATAGAATTGTGCACTTTTTGGCTCCAGTGGTGATGCTGGGGGCAACCGTGCTTTCGTTTGCGGTCAT
TCCGTGGGGGCGCATGTTCCCCGTCGATTTGAACGCCGCCGTGTTGTTTGTGATCGCGACTGGCGGTTTGCACAGCATTG
GCATGATGATGGCTGGTTGGGGTTCCAACAATAAATTTGCCTTGCTGGGGGGGATGCGCGGGGTTGCGCAATTGATCAGC
TATGAAATTCCCCAAGTTATGGCGATTATTCCCGTGGTGTTGATGACAGGCTCGATGTCGCTGCAAAAGATTGTCGAAGC
ACAAAATGACTTTGGCGGCTTGGGCTGGTTTGTCTTCTCACCAGTGGGCTTGTTGGGCTTTGCCTTGTTCTTCACAGCCA
GTTTGGCCGAAGGCGAGCGCACACCCTTTGATATTCCCGAAGCCGACTCAGAAATTATCGCAGGCTATATGACCGAATAT
AGCGGCATGAAGTTTGCGGTTTTCTATCTCTCAAACTACATGAGCAACCTAGCCGTCTGTTTTATCACCGCGACCCTCTA
CCTTGGTGGTGGCAACGGGCCTGGGGTTGATGCGCTGGGTGGCTTTGCTGGTGGTTTGCTTTCACTGATTTACTTCCTGC
TCAAGTCCTTCGCGCTGTTCTTTATCATGGTCTTGATCCGTGCAACAGTACCACGTTTGCGGGTTGACCAACTGATGGGC
TTTGCTTGGAAGTTCTTGCTGCCCTTGGTATTGGTCAACATTCTCAGCGCCTCGTTCTGGGTAGCGCTGCTGCGCTGGGA
TCAACAATGGCCGCAATTGACCGAGTGGTTTGGTGCACCAAGCACTGCTGATGCCACCAATTGGGGGCGTTTGGCAATTG
CCGTAGTGCTGACCCTCTTGATCAATGCAGGGGCTGTCGCGCTGATTATGCGCCTGACCAACCGCAACGTCCAGAAACAC
TTATACACAACCGACGAAGAACTTGCTCTTGGATTATCGTAA

Upstream 100 bases:

>100_bases
TGGCCCAGTTGCGGCAATTGGTCAGAACATGTCGGAAGACAAACGTGCCAAGCTTGAGGCAATTCGCGCTGCGAAACGTG
CCCAACGAGGAGAATAATCG

Downstream 100 bases:

>100_bases
AAGCGCAAGCGTGAAGGATGGGGCGATTGCTCCATCCTTCATACGGAAGGACTAGCTTGATGAACCCGATTGCGATAGGT
GTTTTTATTGTCATCGCGCT

Product: NADH dehydrogenase (quinone)

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MADALTQLGFASWLSVLIASIIKVTLILVGGSVGMMFLTWYERRAISYMQDRRGPNRVGPQGLLQPISEAIKTMTKEDAT
PREADRIVHFLAPVVMLGATVLSFAVIPWGRMFPVDLNAAVLFVIATGGLHSIGMMMAGWGSNNKFALLGGMRGVAQLIS
YEIPQVMAIIPVVLMTGSMSLQKIVEAQNDFGGLGWFVFSPVGLLGFALFFTASLAEGERTPFDIPEADSEIIAGYMTEY
SGMKFAVFYLSNYMSNLAVCFITATLYLGGGNGPGVDALGGFAGGLLSLIYFLLKSFALFFIMVLIRATVPRLRVDQLMG
FAWKFLLPLVLVNILSASFWVALLRWDQQWPQLTEWFGAPSTADATNWGRLAIAVVLTLLINAGAVALIMRLTNRNVQKH
LYTTDEELALGLS

Sequences:

>Translated_413_residues
MADALTQLGFASWLSVLIASIIKVTLILVGGSVGMMFLTWYERRAISYMQDRRGPNRVGPQGLLQPISEAIKTMTKEDAT
PREADRIVHFLAPVVMLGATVLSFAVIPWGRMFPVDLNAAVLFVIATGGLHSIGMMMAGWGSNNKFALLGGMRGVAQLIS
YEIPQVMAIIPVVLMTGSMSLQKIVEAQNDFGGLGWFVFSPVGLLGFALFFTASLAEGERTPFDIPEADSEIIAGYMTEY
SGMKFAVFYLSNYMSNLAVCFITATLYLGGGNGPGVDALGGFAGGLLSLIYFLLKSFALFFIMVLIRATVPRLRVDQLMG
FAWKFLLPLVLVNILSASFWVALLRWDQQWPQLTEWFGAPSTADATNWGRLAIAVVLTLLINAGAVALIMRLTNRNVQKH
LYTTDEELALGLS
>Mature_412_residues
ADALTQLGFASWLSVLIASIIKVTLILVGGSVGMMFLTWYERRAISYMQDRRGPNRVGPQGLLQPISEAIKTMTKEDATP
READRIVHFLAPVVMLGATVLSFAVIPWGRMFPVDLNAAVLFVIATGGLHSIGMMMAGWGSNNKFALLGGMRGVAQLISY
EIPQVMAIIPVVLMTGSMSLQKIVEAQNDFGGLGWFVFSPVGLLGFALFFTASLAEGERTPFDIPEADSEIIAGYMTEYS
GMKFAVFYLSNYMSNLAVCFITATLYLGGGNGPGVDALGGFAGGLLSLIYFLLKSFALFFIMVLIRATVPRLRVDQLMGF
AWKFLLPLVLVNILSASFWVALLRWDQQWPQLTEWFGAPSTADATNWGRLAIAVVLTLLINAGAVALIMRLTNRNVQKHL
YTTDEELALGLS

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=298, Percent_Identity=35.9060402684564, Blast_Score=182, Evalue=5e-46,
Organism=Escherichia coli, GI1788618, Length=343, Percent_Identity=37.3177842565598, Blast_Score=213, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 45006; Mature: 44875

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00626 RCC1_2 ; PS00962 RIBOSOMAL_S2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADALTQLGFASWLSVLIASIIKVTLILVGGSVGMMFLTWYERRAISYMQDRRGPNRVGP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCH
QGLLQPISEAIKTMTKEDATPREADRIVHFLAPVVMLGATVLSFAVIPWGRMFPVDLNAA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
VLFVIATGGLHSIGMMMAGWGSNNKFALLGGMRGVAQLISYEIPQVMAIIPVVLMTGSMS
EEEEEECCCHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LQKIVEAQNDFGGLGWFVFSPVGLLGFALFFTASLAEGERTPFDIPEADSEIIAGYMTEY
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
SGMKFAVFYLSNYMSNLAVCFITATLYLGGGNGPGVDALGGFAGGLLSLIYFLLKSFALF
CCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FIMVLIRATVPRLRVDQLMGFAWKFLLPLVLVNILSASFWVALLRWDQQWPQLTEWFGAP
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
STADATNWGRLAIAVVLTLLINAGAVALIMRLTNRNVQKHLYTTDEELALGLS
CCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCCHHHHCCCC
>Mature Secondary Structure 
ADALTQLGFASWLSVLIASIIKVTLILVGGSVGMMFLTWYERRAISYMQDRRGPNRVGP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCH
QGLLQPISEAIKTMTKEDATPREADRIVHFLAPVVMLGATVLSFAVIPWGRMFPVDLNAA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
VLFVIATGGLHSIGMMMAGWGSNNKFALLGGMRGVAQLISYEIPQVMAIIPVVLMTGSMS
EEEEEECCCHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LQKIVEAQNDFGGLGWFVFSPVGLLGFALFFTASLAEGERTPFDIPEADSEIIAGYMTEY
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
SGMKFAVFYLSNYMSNLAVCFITATLYLGGGNGPGVDALGGFAGGLLSLIYFLLKSFALF
CCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FIMVLIRATVPRLRVDQLMGFAWKFLLPLVLVNILSASFWVALLRWDQQWPQLTEWFGAP
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
STADATNWGRLAIAVVLTLLINAGAVALIMRLTNRNVQKHLYTTDEELALGLS
CCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA