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The map label for this gene is moaC

Identifier: 159901371

GI number: 159901371

Start: 6194553

End: 6195047

Strand: Direct

Name: moaC

Synonym: Haur_4860

Alternate gene names: 159901371

Gene position: 6194553-6195047 (Clockwise)

Preceding gene: 159901370

Following gene: 159901372

Centisome position: 97.6

GC content: 53.74

Gene sequence:

>495_bases
ATGTTGACCCATCTTGATGATCAAGGGCGAGCGCATATGGTTGATGTTGGTGACAAGGCAGTTACCCAACGCCAAGCCCA
AGCCCAAGCCGATGTGCGCATGCAACCAGCAACCTTAGATCTTTTGGTGGCCGGAGAATTGCCCAAAGGCGATGTTTTGG
CAACCGCCCGCATCGCTGGAATTATGGCAGCCAAACGTACTGCCGACTTAATTCCCTTGTGTCATCCACTCCCGCTAAGT
TCCGTAGCGATTGAAATCGAGGCGCATCCTGCGCAATCGCTGCTTCGTATCATCAGCACGGTGCGTTGCACAGGCCGCAC
TGGCGTAGAAATGGAGGCGCTGATGGCAGCATCAGTCGCAGCCTTGACCATTTACGATATGGCCAAAGCTGTTGATCGTG
CTATGGTGATCGAGCAGGTTTTTGTTCGGAATAAAACGGGCGGCGCACGGGGCGATTTCCAGCATCCCCTAACTCCGCTT
GATACCTCAGAGTAA

Upstream 100 bases:

>100_bases
CAATTAATCGATGTGCGCGAAACTGGCTTAGTGCCCCAAGTTGTTGATCAACTCGAACGGACGCTGGCTCATTTCGCGGT
TTGAGGAAACCAAACGATTC

Downstream 100 bases:

>100_bases
GCTTTGATTATCGAGCGTGTAGAGCCTCGCCTGAGACCTACGTTTGTCCCAACGATGTGGCAGAATGGTCATGAAAGGTT
GTCTCTATGCGTGCAATTGT

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MLTHLDDQGRAHMVDVGDKAVTQRQAQAQADVRMQPATLDLLVAGELPKGDVLATARIAGIMAAKRTADLIPLCHPLPLS
SVAIEIEAHPAQSLLRIISTVRCTGRTGVEMEALMAASVAALTIYDMAKAVDRAMVIEQVFVRNKTGGARGDFQHPLTPL
DTSE

Sequences:

>Translated_164_residues
MLTHLDDQGRAHMVDVGDKAVTQRQAQAQADVRMQPATLDLLVAGELPKGDVLATARIAGIMAAKRTADLIPLCHPLPLS
SVAIEIEAHPAQSLLRIISTVRCTGRTGVEMEALMAASVAALTIYDMAKAVDRAMVIEQVFVRNKTGGARGDFQHPLTPL
DTSE
>Mature_164_residues
MLTHLDDQGRAHMVDVGDKAVTQRQAQAQADVRMQPATLDLLVAGELPKGDVLATARIAGIMAAKRTADLIPLCHPLPLS
SVAIEIEAHPAQSLLRIISTVRCTGRTGVEMEALMAASVAALTIYDMAKAVDRAMVIEQVFVRNKTGGARGDFQHPLTPL
DTSE

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=153, Percent_Identity=59.4771241830065, Blast_Score=172, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI32566331, Length=148, Percent_Identity=42.5675675675676, Blast_Score=127, Evalue=4e-30,
Organism=Drosophila melanogaster, GI28574490, Length=153, Percent_Identity=53.5947712418301, Blast_Score=153, Evalue=5e-38,
Organism=Drosophila melanogaster, GI28574492, Length=143, Percent_Identity=52.4475524475524, Blast_Score=140, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_HERA2 (A9B327)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001547618.1
- ProteinModelPortal:   A9B327
- SMR:   A9B327
- GeneID:   5736706
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_4860
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- BioCyc:   HAUR316274:HAUR_4860-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17519; Mature: 17519

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: ACT_SITE 126-126

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTHLDDQGRAHMVDVGDKAVTQRQAQAQADVRMQPATLDLLVAGELPKGDVLATARIAG
CCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCEECCCEEEEEEECCCCCCCCHHHHHHHH
IMAAKRTADLIPLCHPLPLSSVAIEIEAHPAQSLLRIISTVRCTGRTGVEMEALMAASVA
HHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ALTIYDMAKAVDRAMVIEQVFVRNKTGGARGDFQHPLTPLDTSE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLTHLDDQGRAHMVDVGDKAVTQRQAQAQADVRMQPATLDLLVAGELPKGDVLATARIAG
CCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCEECCCEEEEEEECCCCCCCCHHHHHHHH
IMAAKRTADLIPLCHPLPLSSVAIEIEAHPAQSLLRIISTVRCTGRTGVEMEALMAASVA
HHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ALTIYDMAKAVDRAMVIEQVFVRNKTGGARGDFQHPLTPLDTSE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA