Click here to switch to the map view.

The map label for this gene is rsbRA [H]

Identifier: 159901369

GI number: 159901369

Start: 6193159

End: 6194046

Strand: Direct

Name: rsbRA [H]

Synonym: Haur_4858

Alternate gene names: 159901369

Gene position: 6193159-6194046 (Clockwise)

Preceding gene: 159901358

Following gene: 159901370

Centisome position: 97.58

GC content: 49.66

Gene sequence:

>888_bases
ATGAGCGTCGAACATGCATTAGCCGACTTTCTAGAAGCCAATCTTGGGCGCTTCGCCAAACATACTGGTGAGTTGCTGCG
CCAAATTCCCAATTCGCCCTATCCTAAGCTCTCGGACGCAGAGTTGATTCCCCGCATGCAAAAACCGTTTGTGGCGACAA
TTTCGGCTTTGCGCGGCGATTTACAAGCGTTAATCGATTTTTCACGTCAATCGATCAAGCCTGTCGTCGATAATCCCAAC
GCTAGCAGCGACATTGTGGCCCAAATTGGCGAGGCGATTTATAGCACGCTCAAAGTTGCTGCCCGCGAATGTTTCGCCGA
TGATGAATTGAATTATGCCTTGGCGTTGGCCGCCGCCGCTGAAGTGACCTTTATCTCAAATAAAAATAGCTATCAAGCCT
TTGTCGATATCCGCGAAGCCCGCATTCGCGAGCGCGAAGAAACCTTGCAGCAAATGACCAGTGAGCTGGATCAAGCCAAT
GCGGCCTTGCGCGAACTGGCAGCACCAATTGCGCCAATTCACGATAATATTTTGGTCTTGCCCTTGGTTGGCTCGATCGA
TACTAACCGCGCTCAAATGCTGACCGAAGATCTGCTTGAGCAAATTGTCGCACGCCAATCGGATATTGTGATTATGGATA
TCACAGGCGTGCCGATTGTTGATACCAATATCGCTAATTATTTGGTGCAAACCACCAAGGCCGTAAGTTTGTTGGGGGCA
CAAGTAATTCTGGTCGGCATTAGCGCCGAAGTTGCCCAAACAATTGTTGGCCTCGAAATCGATTTGCGCCAATTGTCGGT
TCGTGCCAACTTACAAGATGGCATCGAATATGCGCTCGAACAAGTTGGACTTGGCATTCGCCCATTACAAGAGCAACGGC
GTGGCTAA

Upstream 100 bases:

>100_bases
AGAGAACCATAGAAGCCAACCGCAGAAACGGGTATAATCACCATTGTACGAGACAAACGGGCGCTGACGATCAGCAATTT
AGTCAATAACGAGGATACCA

Downstream 100 bases:

>100_bases
ACTCAATTGGCACGATCAACGTCCGTTAATTTTGCTCGATATTGATGGTGTCATCAATATGTTTGGCCGTTTGGGGCGCG
AACAACAGCAAATCCCGCCG

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MSVEHALADFLEANLGRFAKHTGELLRQIPNSPYPKLSDAELIPRMQKPFVATISALRGDLQALIDFSRQSIKPVVDNPN
ASSDIVAQIGEAIYSTLKVAARECFADDELNYALALAAAAEVTFISNKNSYQAFVDIREARIREREETLQQMTSELDQAN
AALRELAAPIAPIHDNILVLPLVGSIDTNRAQMLTEDLLEQIVARQSDIVIMDITGVPIVDTNIANYLVQTTKAVSLLGA
QVILVGISAEVAQTIVGLEIDLRQLSVRANLQDGIEYALEQVGLGIRPLQEQRRG

Sequences:

>Translated_295_residues
MSVEHALADFLEANLGRFAKHTGELLRQIPNSPYPKLSDAELIPRMQKPFVATISALRGDLQALIDFSRQSIKPVVDNPN
ASSDIVAQIGEAIYSTLKVAARECFADDELNYALALAAAAEVTFISNKNSYQAFVDIREARIREREETLQQMTSELDQAN
AALRELAAPIAPIHDNILVLPLVGSIDTNRAQMLTEDLLEQIVARQSDIVIMDITGVPIVDTNIANYLVQTTKAVSLLGA
QVILVGISAEVAQTIVGLEIDLRQLSVRANLQDGIEYALEQVGLGIRPLQEQRRG
>Mature_294_residues
SVEHALADFLEANLGRFAKHTGELLRQIPNSPYPKLSDAELIPRMQKPFVATISALRGDLQALIDFSRQSIKPVVDNPNA
SSDIVAQIGEAIYSTLKVAARECFADDELNYALALAAAAEVTFISNKNSYQAFVDIREARIREREETLQQMTSELDQANA
ALRELAAPIAPIHDNILVLPLVGSIDTNRAQMLTEDLLEQIVARQSDIVIMDITGVPIVDTNIANYLVQTTKAVSLLGAQ
VILVGISAEVAQTIVGLEIDLRQLSVRANLQDGIEYALEQVGLGIRPLQEQRRG

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 32264; Mature: 32133

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVEHALADFLEANLGRFAKHTGELLRQIPNSPYPKLSDAELIPRMQKPFVATISALRGD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHH
LQALIDFSRQSIKPVVDNPNASSDIVAQIGEAIYSTLKVAARECFADDELNYALALAAAA
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
EVTFISNKNSYQAFVDIREARIREREETLQQMTSELDQANAALRELAAPIAPIHDNILVL
HEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
PLVGSIDTNRAQMLTEDLLEQIVARQSDIVIMDITGVPIVDTNIANYLVQTTKAVSLLGA
EEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEECCHHHHHHHHHHHHHHHHHH
QVILVGISAEVAQTIVGLEIDLRQLSVRANLQDGIEYALEQVGLGIRPLQEQRRG
HHHEEECCHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHCCC
>Mature Secondary Structure 
SVEHALADFLEANLGRFAKHTGELLRQIPNSPYPKLSDAELIPRMQKPFVATISALRGD
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHH
LQALIDFSRQSIKPVVDNPNASSDIVAQIGEAIYSTLKVAARECFADDELNYALALAAAA
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
EVTFISNKNSYQAFVDIREARIREREETLQQMTSELDQANAALRELAAPIAPIHDNILVL
HEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
PLVGSIDTNRAQMLTEDLLEQIVARQSDIVIMDITGVPIVDTNIANYLVQTTKAVSLLGA
EEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEECCHHHHHHHHHHHHHHHHHH
QVILVGISAEVAQTIVGLEIDLRQLSVRANLQDGIEYALEQVGLGIRPLQEQRRG
HHHEEECCHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]