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The map label for this gene is moaB [H]

Identifier: 159901322

GI number: 159901322

Start: 6139332

End: 6139847

Strand: Reverse

Name: moaB [H]

Synonym: Haur_4811

Alternate gene names: 159901322

Gene position: 6139847-6139332 (Counterclockwise)

Preceding gene: 159901325

Following gene: 159901321

Centisome position: 96.74

GC content: 51.36

Gene sequence:

>516_bases
ATGGGCTACAATGATCATGCTGAGGCAGCGGCACAACATCAAGCACCAGTGCGCTGCGCAATTATTACCATTAGCGATAC
GCGAACCAGCGAAACCGATAAGAGTGGGGCGTTGACCCAGGAATTATTAACTGCCGCAGGTTTTCAAGTGGTCGAATATC
GAATTATTCCCGATGAACCAGATCAAGTTGCGGAGTTTGTGCAACAGTGCATTGCGCGGAGCGATTGCGACGCGGTTTTA
ACCAATGGTGGCACTGGGATTGCCCGCCGTGATGCCACAATTGAGGCGATTGCCCCGTTGCTTGATAAAAAATTGCCTGG
GTTTGGCGAAATTTTTCGCATGCTTTCCTACAACGAAATTGGCGCAGGAGCCATGCTTTCACGCGCGATCGCGGGCATCG
CTGGCCGAACCTTGGTTTTTTGTATGCCTGGCTCGTCGGGAGCGGTGCGTTTGGCCATGCAATCGTTGATTTTGCCTGAA
TTAAAACACCTCGTTTGGGAAATAGCCCGCCAGTAA

Upstream 100 bases:

>100_bases
ACGACTCCTTGGACATACTTGGCTTGATTATCACCCTATAGCCAGCTTTGAGCAAATGCGCTACGATAGGCAGAATGCCC
GATTTAATGAAGGAGGTCGT

Downstream 100 bases:

>100_bases
CGCCATAATACCGAATCAGCCAACCAAGCCCAAGCAAACCAAGCAGCCAAGGCCAGAACGTTGGCAAGTTTGGTTGGCTG
GTCGCTGGCAACCGTTGCGG

Product: molybdenum cofactor synthesis domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MGYNDHAEAAAQHQAPVRCAIITISDTRTSETDKSGALTQELLTAAGFQVVEYRIIPDEPDQVAEFVQQCIARSDCDAVL
TNGGTGIARRDATIEAIAPLLDKKLPGFGEIFRMLSYNEIGAGAMLSRAIAGIAGRTLVFCMPGSSGAVRLAMQSLILPE
LKHLVWEIARQ

Sequences:

>Translated_171_residues
MGYNDHAEAAAQHQAPVRCAIITISDTRTSETDKSGALTQELLTAAGFQVVEYRIIPDEPDQVAEFVQQCIARSDCDAVL
TNGGTGIARRDATIEAIAPLLDKKLPGFGEIFRMLSYNEIGAGAMLSRAIAGIAGRTLVFCMPGSSGAVRLAMQSLILPE
LKHLVWEIARQ
>Mature_170_residues
GYNDHAEAAAQHQAPVRCAIITISDTRTSETDKSGALTQELLTAAGFQVVEYRIIPDEPDQVAEFVQQCIARSDCDAVLT
NGGTGIARRDATIEAIAPLLDKKLPGFGEIFRMLSYNEIGAGAMLSRAIAGIAGRTLVFCMPGSSGAVRLAMQSLILPEL
KHLVWEIARQ

Specific function: Maybe involved in the biosynthesis of molybdopterin [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=160, Percent_Identity=33.125, Blast_Score=87, Evalue=9e-18,
Organism=Homo sapiens, GI10880983, Length=160, Percent_Identity=33.125, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1787000, Length=146, Percent_Identity=43.1506849315069, Blast_Score=127, Evalue=4e-31,
Organism=Escherichia coli, GI1786190, Length=145, Percent_Identity=33.1034482758621, Blast_Score=77, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17564954, Length=155, Percent_Identity=35.4838709677419, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17136978, Length=151, Percent_Identity=38.4105960264901, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24638841, Length=151, Percent_Identity=38.4105960264901, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18358; Mature: 18227

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYNDHAEAAAQHQAPVRCAIITISDTRTSETDKSGALTQELLTAAGFQVVEYRIIPDEP
CCCCCHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCH
DQVAEFVQQCIARSDCDAVLTNGGTGIARRDATIEAIAPLLDKKLPGFGEIFRMLSYNEI
HHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCC
GAGAMLSRAIAGIAGRTLVFCMPGSSGAVRLAMQSLILPELKHLVWEIARQ
CHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GYNDHAEAAAQHQAPVRCAIITISDTRTSETDKSGALTQELLTAAGFQVVEYRIIPDEP
CCCCHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCH
DQVAEFVQQCIARSDCDAVLTNGGTGIARRDATIEAIAPLLDKKLPGFGEIFRMLSYNEI
HHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCC
GAGAMLSRAIAGIAGRTLVFCMPGSSGAVRLAMQSLILPELKHLVWEIARQ
CHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]