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The map label for this gene is mtnU [H]

Identifier: 159901285

GI number: 159901285

Start: 6088945

End: 6089724

Strand: Reverse

Name: mtnU [H]

Synonym: Haur_4773

Alternate gene names: 159901285

Gene position: 6089724-6088945 (Counterclockwise)

Preceding gene: 159901286

Following gene: 159901281

Centisome position: 95.95

GC content: 53.33

Gene sequence:

>780_bases
ATGCAGTTAACCGTGGCACTTGCTCAAATCGATTTAGTGTTGGGCGATCGCGAAGCCAATTTAGCGACGGTGCGTCAACT
TGCTGCGCGTGCCGAGATGGCAGGCGCAGCGCTGTTGGTGTTGCCAGAGTTATGGGGCACTGGCTATCTGCTGGAACAAG
CCCACGAATTGAGCGATCCGCTCGGCAAGGGCTTGTTTGAAGAAGTCGCGGTTTTGGCGGCCCGCCATCATTTGGCGATT
GTTGGCTCATTGCTGGAACGTGATGGCGAGCAGGTTTATAACACGGCCACGCTATATGATGCACAGGGCAAACGTCTCCA
TAGTTATCGCAAAACCCACCTGATTGGCTTGATGCAAGAAGATCGCTATCTGGCTGCTGGTCAGCAAGCCGAAGTTTTTG
AAACTGCTTGGGGCACAAGTGCATGCGCCATTTGCTACGATTTACGCTTTCCTGAATTGTTTCGGCGTTACGCCTTGGCT
GGCGCAGGAGTGATAATTATTCCAGCTGAATGGCCAACAGCGCGAATTGAGCATTGGCGTACCTTGCTTCGCGCACGGGC
GATCGAAAACCAAGCTGTGGTCATCGCCTGTAATCGGGTTGGCAGCGACCGTGCTAATCAATTTGGTGGTCACTCCGTCG
TGATTGACCCTTGGGGCAAGGTTTTGGTTGAGGGCGATGATCAAGCTGGCCTATTGACTGCAACTGTTGATCTTGCCAGC
ATTGCCAAAGCCCGCGACTTCCTGCCAGTCTTTCGTGATCGACGGGTTGAGTTGTACTAG

Upstream 100 bases:

>100_bases
TGATGTGCTACGAGCCTATAATGGCGAGGCCTTCCCCGATATTAATGGTAATTTGCCTGCGCCTGCTGCTGGCAGCACTG
GCCAATAGAGGAAAAAACCA

Downstream 100 bases:

>100_bases
AACTAGATATCAGGATGCAGAGGCAAGGAATCAGATTTTTTTAATCACCAAGTAAGGCTACAGACTATCGGCTATCGGAG
ATTGGATTAAAATACCAAAA

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MQLTVALAQIDLVLGDREANLATVRQLAARAEMAGAALLVLPELWGTGYLLEQAHELSDPLGKGLFEEVAVLAARHHLAI
VGSLLERDGEQVYNTATLYDAQGKRLHSYRKTHLIGLMQEDRYLAAGQQAEVFETAWGTSACAICYDLRFPELFRRYALA
GAGVIIIPAEWPTARIEHWRTLLRARAIENQAVVIACNRVGSDRANQFGGHSVVIDPWGKVLVEGDDQAGLLTATVDLAS
IAKARDFLPVFRDRRVELY

Sequences:

>Translated_259_residues
MQLTVALAQIDLVLGDREANLATVRQLAARAEMAGAALLVLPELWGTGYLLEQAHELSDPLGKGLFEEVAVLAARHHLAI
VGSLLERDGEQVYNTATLYDAQGKRLHSYRKTHLIGLMQEDRYLAAGQQAEVFETAWGTSACAICYDLRFPELFRRYALA
GAGVIIIPAEWPTARIEHWRTLLRARAIENQAVVIACNRVGSDRANQFGGHSVVIDPWGKVLVEGDDQAGLLTATVDLAS
IAKARDFLPVFRDRRVELY
>Mature_259_residues
MQLTVALAQIDLVLGDREANLATVRQLAARAEMAGAALLVLPELWGTGYLLEQAHELSDPLGKGLFEEVAVLAARHHLAI
VGSLLERDGEQVYNTATLYDAQGKRLHSYRKTHLIGLMQEDRYLAAGQQAEVFETAWGTSACAICYDLRFPELFRRYALA
GAGVIIIPAEWPTARIEHWRTLLRARAIENQAVVIACNRVGSDRANQFGGHSVVIDPWGKVLVEGDDQAGLLTATVDLAS
IAKARDFLPVFRDRRVELY

Specific function: May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway [H]

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI297632350, Length=276, Percent_Identity=37.3188405797101, Blast_Score=138, Evalue=6e-33,
Organism=Homo sapiens, GI5031947, Length=276, Percent_Identity=37.3188405797101, Blast_Score=138, Evalue=6e-33,
Organism=Homo sapiens, GI297632348, Length=276, Percent_Identity=37.3188405797101, Blast_Score=137, Evalue=7e-33,
Organism=Homo sapiens, GI9910460, Length=264, Percent_Identity=29.5454545454545, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI297632346, Length=184, Percent_Identity=34.2391304347826, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI7706509, Length=212, Percent_Identity=29.7169811320755, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1786412, Length=254, Percent_Identity=33.0708661417323, Blast_Score=106, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17556280, Length=260, Percent_Identity=30.7692307692308, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17533173, Length=222, Percent_Identity=28.3783783783784, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323383, Length=276, Percent_Identity=28.9855072463768, Blast_Score=130, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6322335, Length=302, Percent_Identity=26.8211920529801, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21355835, Length=257, Percent_Identity=30.3501945525292, Blast_Score=121, Evalue=4e-28,
Organism=Drosophila melanogaster, GI17933642, Length=271, Percent_Identity=32.8413284132841, Blast_Score=117, Evalue=6e-27,
Organism=Drosophila melanogaster, GI21358471, Length=294, Percent_Identity=27.891156462585, Blast_Score=88, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 28558; Mature: 28558

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLTVALAQIDLVLGDREANLATVRQLAARAEMAGAALLVLPELWGTGYLLEQAHELSDP
CEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEEHHHCCCCHHHHHHHHHHCH
LGKGLFEEVAVLAARHHLAIVGSLLERDGEQVYNTATLYDAQGKRLHSYRKTHLIGLMQE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEHEEECCCCHHHHHHHHHHHEEECCC
DRYLAAGQQAEVFETAWGTSACAICYDLRFPELFRRYALAGAGVIIIPAEWPTARIEHWR
CCEECCCCCHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
TLLRARAIENQAVVIACNRVGSDRANQFGGHSVVIDPWGKVLVEGDDQAGLLTATVDLAS
HHHHHHHCCCCEEEEEECCCCCCHHHHCCCCEEEECCCCEEEEECCCCCCEEEEHHHHHH
IAKARDFLPVFRDRRVELY
HHHHHHHHHHHHCCCEECC
>Mature Secondary Structure
MQLTVALAQIDLVLGDREANLATVRQLAARAEMAGAALLVLPELWGTGYLLEQAHELSDP
CEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEEHHHCCCCHHHHHHHHHHCH
LGKGLFEEVAVLAARHHLAIVGSLLERDGEQVYNTATLYDAQGKRLHSYRKTHLIGLMQE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEHEEECCCCHHHHHHHHHHHEEECCC
DRYLAAGQQAEVFETAWGTSACAICYDLRFPELFRRYALAGAGVIIIPAEWPTARIEHWR
CCEECCCCCHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
TLLRARAIENQAVVIACNRVGSDRANQFGGHSVVIDPWGKVLVEGDDQAGLLTATVDLAS
HHHHHHHCCCCEEEEEECCCCCCHHHHCCCCEEEECCCCEEEEECCCCCCEEEEHHHHHH
IAKARDFLPVFRDRRVELY
HHHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]