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The map label for this gene is ruvC [H]

Identifier: 159901265

GI number: 159901265

Start: 6060750

End: 6061247

Strand: Reverse

Name: ruvC [H]

Synonym: Haur_4753

Alternate gene names: 159901265

Gene position: 6061247-6060750 (Counterclockwise)

Preceding gene: 159901266

Following gene: 159901264

Centisome position: 95.5

GC content: 52.01

Gene sequence:

>498_bases
ATGCGGATTATCGGGATCGATCCAGGCACGGCAATTATGGGTTGGGGCATTATTGATGCCGATGGCAGCGATTTGACCAT
GGTTGCCTATGGCGCGTTTACCACGCCCGCCAAACAGCCGCTGCCCGATCGCTTGGTGAGCATTTACAATGATTTAGCCC
ATGTGTTGGAGCACTATCGGCCTAGCGTTGCCGCAGTTGAAGAATTGTTTTTTGCCAAAAATGTAACAACTGCGATGGCC
GTGAGCCATGCGCGTGGGGTGGCCTTGTTGGCCTTGCGCCAAGCCAAATTGCCAATTTTTGAATATAAACCGTTGTCTGT
GAAACAGGCCGTGGTCGGATATGGCAACGCCGACAAACAGCAAATGCAACATCTGGTGCAAATGACCCTGAATTTGGATC
ATATTCCCAAGCCCGATGATGCCGCTGATGCCCTTGCCGTTGCCATGTGCCATGCCTACGCAGCACCGTATCTTAACCGC
ATTCAGGAGGATTCCTAG

Upstream 100 bases:

>100_bases
GGCTATGTTGAATTGACTGGCTACGGCGATAGCGACCGCGGGCGTGCCGAATAAGCGAAAGCCGTTATAATGCAATCAGC
ATAATCATTGAGGATCAGCA

Downstream 100 bases:

>100_bases
ATGGTTCGTCGGCCAGATCTTGAAGAAGTCAGAGTTAATACCTTTTTAATTGCAGATACCGCCATGATTCCGATTTTGCG
TGGTGAGGGCACGGTCAATG

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MRIIGIDPGTAIMGWGIIDADGSDLTMVAYGAFTTPAKQPLPDRLVSIYNDLAHVLEHYRPSVAAVEELFFAKNVTTAMA
VSHARGVALLALRQAKLPIFEYKPLSVKQAVVGYGNADKQQMQHLVQMTLNLDHIPKPDDAADALAVAMCHAYAAPYLNR
IQEDS

Sequences:

>Translated_165_residues
MRIIGIDPGTAIMGWGIIDADGSDLTMVAYGAFTTPAKQPLPDRLVSIYNDLAHVLEHYRPSVAAVEELFFAKNVTTAMA
VSHARGVALLALRQAKLPIFEYKPLSVKQAVVGYGNADKQQMQHLVQMTLNLDHIPKPDDAADALAVAMCHAYAAPYLNR
IQEDS
>Mature_165_residues
MRIIGIDPGTAIMGWGIIDADGSDLTMVAYGAFTTPAKQPLPDRLVSIYNDLAHVLEHYRPSVAAVEELFFAKNVTTAMA
VSHARGVALLALRQAKLPIFEYKPLSVKQAVVGYGNADKQQMQHLVQMTLNLDHIPKPDDAADALAVAMCHAYAAPYLNR
IQEDS

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=135, Percent_Identity=40, Blast_Score=111, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 17959; Mature: 17959

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00124 FBPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIIGIDPGTAIMGWGIIDADGSDLTMVAYGAFTTPAKQPLPDRLVSIYNDLAHVLEHYR
CEEEECCCCCEEEECEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
PSVAAVEELFFAKNVTTAMAVSHARGVALLALRQAKLPIFEYKPLSVKQAVVGYGNADKQ
CHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHCCCEECCCCCCHHHHHHCCCCCCHH
QMQHLVQMTLNLDHIPKPDDAADALAVAMCHAYAAPYLNRIQEDS
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRIIGIDPGTAIMGWGIIDADGSDLTMVAYGAFTTPAKQPLPDRLVSIYNDLAHVLEHYR
CEEEECCCCCEEEECEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
PSVAAVEELFFAKNVTTAMAVSHARGVALLALRQAKLPIFEYKPLSVKQAVVGYGNADKQ
CHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHCCCEECCCCCCHHHHHHCCCCCCHH
QMQHLVQMTLNLDHIPKPDDAADALAVAMCHAYAAPYLNRIQEDS
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA