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The map label for this gene is efp

Identifier: 159901238

GI number: 159901238

Start: 6037190

End: 6037747

Strand: Direct

Name: efp

Synonym: Haur_4726

Alternate gene names: 159901238

Gene position: 6037190-6037747 (Clockwise)

Preceding gene: 159901237

Following gene: 159901239

Centisome position: 95.12

GC content: 49.64

Gene sequence:

>558_bases
ATGGTCTCAACAGGTGAAGTACGCAAAGGTCTAACCCTCATTATTGATGGTGAATTGTTCCGCGTGATGGAAGCCAACCA
CGTCAAGCAAGGTCGTGGCACGGCATTCTTGCGCCTGACCTTACGCAATGTCCGCACCAGTGCTACAACGGTTAAAACGT
TTATGGCTGGCGAACGCTTCGAAGTTGCCCGCTTGTCAACCCGTAACGTTCAATACCTCTATCGCGAAGATAACTATATC
TATGTGATGAACACTGAAACCTACGATCAATTCCCCGTCAGTGTGGATTTGCTCGAAGATGCGTTGTTGTATATTCGCGA
AAACGAAACGTTCGACGTTTTGACCTACGAAGATGAAGTGCTGGATATTTCGTTGCCACCTTCAGTTGAGATGGTTGTGG
TTGAAACCGAGCCAAACTACAAGGGCGATACCGCTTCAGGTGGTGGCAAGCCTGCAACCACCGACACTGGCTTAGTGGTG
CAAGTGCCTTCATTCGTCGCGGTTGGCGAACGGATTCGGGTTGATACCACCAACGGCAAGTACATTACGCGGATCTAG

Upstream 100 bases:

>100_bases
TGCCAATGGTGTTGAAACGCTTACACAATCGCCACTTGACCCGATCATTGTGATCGAGCAAGCCTAAAATTTATTACAAC
CCAAAGGGAGTTCTTGTATC

Downstream 100 bases:

>100_bases
GTGGGGTTTGACCCATTATTTTAAAGCTGATCATCACGGCGCTGGGCACGAATCCCTGCGCCGTCGCCATTTCTCCTTGT
GTAGTTGAGGATGCTAGCCC

Product: translation elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MVSTGEVRKGLTLIIDGELFRVMEANHVKQGRGTAFLRLTLRNVRTSATTVKTFMAGERFEVARLSTRNVQYLYREDNYI
YVMNTETYDQFPVSVDLLEDALLYIRENETFDVLTYEDEVLDISLPPSVEMVVVETEPNYKGDTASGGGKPATTDTGLVV
QVPSFVAVGERIRVDTTNGKYITRI

Sequences:

>Translated_185_residues
MVSTGEVRKGLTLIIDGELFRVMEANHVKQGRGTAFLRLTLRNVRTSATTVKTFMAGERFEVARLSTRNVQYLYREDNYI
YVMNTETYDQFPVSVDLLEDALLYIRENETFDVLTYEDEVLDISLPPSVEMVVVETEPNYKGDTASGGGKPATTDTGLVV
QVPSFVAVGERIRVDTTNGKYITRI
>Mature_185_residues
MVSTGEVRKGLTLIIDGELFRVMEANHVKQGRGTAFLRLTLRNVRTSATTVKTFMAGERFEVARLSTRNVQYLYREDNYI
YVMNTETYDQFPVSVDLLEDALLYIRENETFDVLTYEDEVLDISLPPSVEMVVVETEPNYKGDTASGGGKPATTDTGLVV
QVPSFVAVGERIRVDTTNGKYITRI

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=182, Percent_Identity=36.8131868131868, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI87082061, Length=188, Percent_Identity=32.9787234042553, Blast_Score=102, Evalue=1e-23,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_HERA2 (A9B1H0)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001547485.1
- ProteinModelPortal:   A9B1H0
- SMR:   A9B1H0
- GeneID:   5736570
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_4726
- HOGENOM:   HBG303311
- OMA:   YIRENET
- BioCyc:   HAUR316274:HAUR_4726-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20803; Mature: 20803

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSTGEVRKGLTLIIDGELFRVMEANHVKQGRGTAFLRLTLRNVRTSATTVKTFMAGERF
CCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCEEEEEEEEECCCCCHHEEEEHHCCCCE
EVARLSTRNVQYLYREDNYIYVMNTETYDQFPVSVDLLEDALLYIRENETFDVLTYEDEV
EEEEECCCCEEEEEECCCEEEEEECCCCCCCCCCHHHHHCEEEEEECCCEEEEEEECCCE
LDISLPPSVEMVVVETEPNYKGDTASGGGKPATTDTGLVVQVPSFVAVGERIRVDTTNGK
EEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCEECCCEEEEECCCCE
YITRI
EEEEC
>Mature Secondary Structure
MVSTGEVRKGLTLIIDGELFRVMEANHVKQGRGTAFLRLTLRNVRTSATTVKTFMAGERF
CCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCEEEEEEEEECCCCCHHEEEEHHCCCCE
EVARLSTRNVQYLYREDNYIYVMNTETYDQFPVSVDLLEDALLYIRENETFDVLTYEDEV
EEEEECCCCEEEEEECCCEEEEEECCCCCCCCCCHHHHHCEEEEEECCCEEEEEEECCCE
LDISLPPSVEMVVVETEPNYKGDTASGGGKPATTDTGLVVQVPSFVAVGERIRVDTTNGK
EEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCEECCCEEEEECCCCE
YITRI
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA