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The map label for this gene is gap1 [H]

Identifier: 159901212

GI number: 159901212

Start: 6004945

End: 6005970

Strand: Direct

Name: gap1 [H]

Synonym: Haur_4700

Alternate gene names: 159901212

Gene position: 6004945-6005970 (Clockwise)

Preceding gene: 159901211

Following gene: 159901213

Centisome position: 94.62

GC content: 49.61

Gene sequence:

>1026_bases
GTGGCACGAGTAGCAATCAACGGCTTCGGTCGCATCGGTCGCCAAAGCTTCAAAACCATCTTGGATCACTATCGCGATGA
GTTGGAAATTGTTGCAATCAACGACCTGACCGATAACCAAACGTTGGCCCACCTGCTCAAGTACGATTCAACCTATGGTT
CATTCGATGGCGATGTTACCGCCACTGAAGATACAATCAGCGTTACCTTCGCCGATGAAGAAGAGCCAATGGTCATCAAG
GCCTTGGCCGAGCGCGATCCGTCAAAATTACCATGGGGTGAGCTCAACGTCGATATCGTAATCGAATCGACTGGGATTTT
TACTGATGCGACCAAAGCCAAAATGCACTTAGATGCAGGCGCGAAGAAAGTCATCATCAGTGCTCCCGCCAAGAACGAAG
ACATCACCGTGTGTATGGGCGTGAACGAAGAAAATTACGACGCTGAAAAACATACGATTGTCTCGAATGCATCATGTACC
ACCAACTGTTTGGCTCCAGTAGCTAAAGTGTTGAACGATAAGTTCGGCATTGTGCGTGGCTTGATGACCACCATTCACTC
ATACACGATGGACCAAAATTTGCAAGACGGCCCCCACAAAGATTTGCGCCGCGCTCGCGCTGCTGCTTTGAACATGGTTC
CAACCACCACGGGTGCTGCTAAAGCTGTAGCTTTGGTTATCCCTGAGTTGAAGGGCAAATTCGATGGTTTCGCCGTGCGC
GTCCCAACCCCAACCGTTTCGATGGTTGACTTTGTGGTTGAATTGGCCGAAGGCGCAACCGTTGAATCGATCAACAATGC
CTTTATTGAAGCCTCAGAAGGCGCAATGGAAGGCGTGTTGGGCGTAACCAATGAAGAACTGGTCTCATCAGACTTCATCG
GTACTTCATACTCAAGCGTGGTTGACTTAAGCTTGACCATGGCAATGGGCGACAAGATGGTCAAAGTTGTTGCTTGGTAC
GACAACGAATGGGGCTATGCTACCCGCATCGCTGACCTCACCGCCTATATCGCTGAAAAACTCTAA

Upstream 100 bases:

>100_bases
AGCAGAATGACAGTAAGCAGTGAATGTGCTATAGTGGTGCAGAACGGCCCAGAGCCGTGAAAGCATTCTTAATTTGGTGC
GAAATAATAAGGAGTCACTT

Downstream 100 bases:

>100_bases
GATCGATTGATCGCAATTGGCCTAAAACGCTGGTGGTTGCAAAAACCACCAGCGTTTGTTGTTTAACCTTGCGCCAACCA
CACTATGGCTAGTTCGCGAG

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH 1 [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MARVAINGFGRIGRQSFKTILDHYRDELEIVAINDLTDNQTLAHLLKYDSTYGSFDGDVTATEDTISVTFADEEEPMVIK
ALAERDPSKLPWGELNVDIVIESTGIFTDATKAKMHLDAGAKKVIISAPAKNEDITVCMGVNEENYDAEKHTIVSNASCT
TNCLAPVAKVLNDKFGIVRGLMTTIHSYTMDQNLQDGPHKDLRRARAAALNMVPTTTGAAKAVALVIPELKGKFDGFAVR
VPTPTVSMVDFVVELAEGATVESINNAFIEASEGAMEGVLGVTNEELVSSDFIGTSYSSVVDLSLTMAMGDKMVKVVAWY
DNEWGYATRIADLTAYIAEKL

Sequences:

>Translated_341_residues
MARVAINGFGRIGRQSFKTILDHYRDELEIVAINDLTDNQTLAHLLKYDSTYGSFDGDVTATEDTISVTFADEEEPMVIK
ALAERDPSKLPWGELNVDIVIESTGIFTDATKAKMHLDAGAKKVIISAPAKNEDITVCMGVNEENYDAEKHTIVSNASCT
TNCLAPVAKVLNDKFGIVRGLMTTIHSYTMDQNLQDGPHKDLRRARAAALNMVPTTTGAAKAVALVIPELKGKFDGFAVR
VPTPTVSMVDFVVELAEGATVESINNAFIEASEGAMEGVLGVTNEELVSSDFIGTSYSSVVDLSLTMAMGDKMVKVVAWY
DNEWGYATRIADLTAYIAEKL
>Mature_340_residues
ARVAINGFGRIGRQSFKTILDHYRDELEIVAINDLTDNQTLAHLLKYDSTYGSFDGDVTATEDTISVTFADEEEPMVIKA
LAERDPSKLPWGELNVDIVIESTGIFTDATKAKMHLDAGAKKVIISAPAKNEDITVCMGVNEENYDAEKHTIVSNASCTT
NCLAPVAKVLNDKFGIVRGLMTTIHSYTMDQNLQDGPHKDLRRARAAALNMVPTTTGAAKAVALVIPELKGKFDGFAVRV
PTPTVSMVDFVVELAEGATVESINNAFIEASEGAMEGVLGVTNEELVSSDFIGTSYSSVVDLSLTMAMGDKMVKVVAWYD
NEWGYATRIADLTAYIAEKL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=340, Percent_Identity=47.3529411764706, Blast_Score=304, Evalue=7e-83,
Organism=Homo sapiens, GI7657116, Length=339, Percent_Identity=45.1327433628319, Blast_Score=301, Evalue=6e-82,
Organism=Escherichia coli, GI1788079, Length=338, Percent_Identity=49.7041420118343, Blast_Score=326, Evalue=1e-90,
Organism=Escherichia coli, GI1789295, Length=338, Percent_Identity=42.3076923076923, Blast_Score=270, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI17534677, Length=341, Percent_Identity=47.5073313782991, Blast_Score=318, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI17534679, Length=341, Percent_Identity=47.2140762463343, Blast_Score=318, Evalue=3e-87,
Organism=Caenorhabditis elegans, GI17568413, Length=339, Percent_Identity=46.6076696165192, Blast_Score=307, Evalue=5e-84,
Organism=Caenorhabditis elegans, GI32566163, Length=339, Percent_Identity=46.6076696165192, Blast_Score=307, Evalue=5e-84,
Organism=Saccharomyces cerevisiae, GI6321631, Length=341, Percent_Identity=51.0263929618768, Blast_Score=331, Evalue=1e-91,
Organism=Saccharomyces cerevisiae, GI6322409, Length=341, Percent_Identity=48.9736070381232, Blast_Score=329, Evalue=4e-91,
Organism=Saccharomyces cerevisiae, GI6322468, Length=341, Percent_Identity=50.4398826979472, Blast_Score=328, Evalue=6e-91,
Organism=Drosophila melanogaster, GI85725000, Length=342, Percent_Identity=47.6608187134503, Blast_Score=308, Evalue=2e-84,
Organism=Drosophila melanogaster, GI22023983, Length=342, Percent_Identity=47.6608187134503, Blast_Score=308, Evalue=2e-84,
Organism=Drosophila melanogaster, GI17933600, Length=342, Percent_Identity=46.7836257309941, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI18110149, Length=342, Percent_Identity=46.7836257309941, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI19922412, Length=338, Percent_Identity=45.2662721893491, Blast_Score=288, Evalue=3e-78,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36958; Mature: 36827

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARVAINGFGRIGRQSFKTILDHYRDELEIVAINDLTDNQTLAHLLKYDSTYGSFDGDVT
CCEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCEE
ATEDTISVTFADEEEPMVIKALAERDPSKLPWGELNVDIVIESTGIFTDATKAKMHLDAG
ECCCEEEEEECCCCCCEEEEEHHHCCCCCCCCCCCEEEEEEECCCCEECCCHHEEEECCC
AKKVIISAPAKNEDITVCMGVNEENYDAEKHTIVSNASCTTNCLAPVAKVLNDKFGIVRG
CCEEEEECCCCCCCEEEEEECCCCCCCCCHHEEEECCCCCHHHHHHHHHHHCCHHHHHHH
LMTTIHSYTMDQNLQDGPHKDLRRARAAALNMVPTTTGAAKAVALVIPELKGKFDGFAVR
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHEEEEEEHHHCCCCCCEEEE
VPTPTVSMVDFVVELAEGATVESINNAFIEASEGAMEGVLGVTNEELVSSDFIGTSYSSV
ECCCCHHHHHHHHHHHCCCCHHHHCHHEEECCCCHHHHHHCCCCHHHHHHCCCCCCHHHH
VDLSLTMAMGDKMVKVVAWYDNEWGYATRIADLTAYIAEKL
EEEEEHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARVAINGFGRIGRQSFKTILDHYRDELEIVAINDLTDNQTLAHLLKYDSTYGSFDGDVT
CEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCEE
ATEDTISVTFADEEEPMVIKALAERDPSKLPWGELNVDIVIESTGIFTDATKAKMHLDAG
ECCCEEEEEECCCCCCEEEEEHHHCCCCCCCCCCCEEEEEEECCCCEECCCHHEEEECCC
AKKVIISAPAKNEDITVCMGVNEENYDAEKHTIVSNASCTTNCLAPVAKVLNDKFGIVRG
CCEEEEECCCCCCCEEEEEECCCCCCCCCHHEEEECCCCCHHHHHHHHHHHCCHHHHHHH
LMTTIHSYTMDQNLQDGPHKDLRRARAAALNMVPTTTGAAKAVALVIPELKGKFDGFAVR
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHEEEEEEHHHCCCCCCEEEE
VPTPTVSMVDFVVELAEGATVESINNAFIEASEGAMEGVLGVTNEELVSSDFIGTSYSSV
ECCCCHHHHHHHHHHHCCCCHHHHCHHEEECCCCHHHHHHCCCCHHHHHHCCCCCCHHHH
VDLSLTMAMGDKMVKVVAWYDNEWGYATRIADLTAYIAEKL
EEEEEHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA