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The map label for this gene is yycG [H]

Identifier: 159901161

GI number: 159901161

Start: 5939300

End: 5940901

Strand: Reverse

Name: yycG [H]

Synonym: Haur_4649

Alternate gene names: 159901161

Gene position: 5940901-5939300 (Counterclockwise)

Preceding gene: 159901172

Following gene: 159901160

Centisome position: 93.61

GC content: 50.19

Gene sequence:

>1602_bases
ATGGCCGCGAATGAACCTGGTCAGGTGACAAGCCCCGAAGATTCATATCAGCGTTTGCGAACCGAGTATGAACGGTTGCA
GTTGCTCTATAGCCTCGCTCAACAGTTTGCGACGATGTTAAGTTTACCCAATGTTTTGCAGCATGTGCTCTCAGCCACAA
CCCGCTTTACCAATGCTGTGCGTGGTAGCATTTTCCTCTATGGCGAGTACGATGAAGTTCAAATGCATTTGCTTTCTGAG
CGTTTTCAACAAGCTCGCTTGACTCCTTTTACTAATCGTATTTTACGCGAAGGCTTGGCAAGTTGGGTGCTCAAGCATCG
CCAAAGTGCCTTAATCGCCGATACCAATCTCGATGAACGTTGGATCGATTATCCCAGTGATACGTTGGATGTACGCTCAG
TGCTGTGTGTGCCGCTTTTGCGTGGGCGACGAGTGCGCGGCGTGCTGACCTTGGTGCATCCTGAAATTGGTTTTTTTACC
ATGGATGATGAGGCGCTGCTGAATGTGATTGCCCAGCATGCAGCCATGGCGATTGAAAATGCCCAGCTGATCGCTGATAT
TAATGATGAGCGGCGCAAGTTCGAGGGAGCTTTCACCGCTATGGAAGAAGGCTTGATTTTGGTTGATGGCGATGGTCGGA
TTCACTTTGTTAATCCCCAAGCCTTAGCCTTTTTTGCGGTCACTCCACCCGTGCCCGAACACCTGAACGAGCTTTCGCAG
CAAGTTTTGGGCTTATTCAAAGAGGCCCAACAAACTGGTGATAGTGTGCGTGCCGAGATTGTGCTTGAGCAGAATCCCAC
CACCGATCTGGCCATCCACATTGCCTACATCCCCATTTTCAGTGAACAAGAAGATTGGTGGACGATCGTGCTCCACGATA
TTACGCGGCTGAAGGAGTATGATCGGCTCAAAACTCAGTTTGTCGCCAATGCTTCGCATGAATTGCGCACGCCTTTGGCC
AATATTAAGTTGTATGCCCGGTTGGCCCAGCAAGTCAAAGCTAAAACCAAGTTACCTCAATATCTCGAAACTATTGCGAG
CGAAGCAGGCCGCTTGGAAGCAATCGTTGAAGATTTGTTGACCCTGACCCGCTTGGATAGCGGCTTGATGCATAGTAGTC
CTGAATGGGTTGATATTATTGAATTGTTGCGCAACTTAGCCCAAACCTATCGCCCGCTGGCCGAAGCGCGGGAACAACGC
TTGATTTTTCAAGAATGTACCAGCAATTTGCCCAAGCTTTGGTTAGCCCCCGATCAATTTATGCGGGTGGTCGTGAACTT
GCTAAGCAATGCCCTAAAATTCACACCAACTGGCGGCACAGTCACGCTATCGGTTGATCGCCAAACCCAAGCGGGGCAGG
CTGGCACGCTTATCACCGTAGCCGACACTGGGCCAGGCATCGCACCTGAACATCAGCAACGCTTATTTGAACGTTTTTAT
CGCGGTAGTAACCCAACCGAGAGTGGTAGCGGTTTAGGTTTAGCCATTGTGCGTGAGTTGTTGGCCTTGATGGGAGGCAC
AATTTCGGTAGCCAGCACCGTTGGTCAAGGTTCGCAATTCACCTGTTGGTTGCCCTTAGAACAACACACTCACACCGCAT
GA

Upstream 100 bases:

>100_bases
TACAGATTAAGCATTGCATGGGGCGATTGTACCGCTCCCCTTGTGGCTTGAAACTCGGTGTTATAATTCCCAAACAATAC
GCATATCTGTGGAGTATCCA

Downstream 100 bases:

>100_bases
TTACTCAATTAATCGTAATTTTGTTCGTAAACTCTCACCCCTAGAGTGGATATGCATTGTCCATTTTTTGACCGTTTTCG
CATCTGTTCTGAAGAAGGAG

Product: GAF sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 532

Protein sequence:

>533_residues
MAANEPGQVTSPEDSYQRLRTEYERLQLLYSLAQQFATMLSLPNVLQHVLSATTRFTNAVRGSIFLYGEYDEVQMHLLSE
RFQQARLTPFTNRILREGLASWVLKHRQSALIADTNLDERWIDYPSDTLDVRSVLCVPLLRGRRVRGVLTLVHPEIGFFT
MDDEALLNVIAQHAAMAIENAQLIADINDERRKFEGAFTAMEEGLILVDGDGRIHFVNPQALAFFAVTPPVPEHLNELSQ
QVLGLFKEAQQTGDSVRAEIVLEQNPTTDLAIHIAYIPIFSEQEDWWTIVLHDITRLKEYDRLKTQFVANASHELRTPLA
NIKLYARLAQQVKAKTKLPQYLETIASEAGRLEAIVEDLLTLTRLDSGLMHSSPEWVDIIELLRNLAQTYRPLAEAREQR
LIFQECTSNLPKLWLAPDQFMRVVVNLLSNALKFTPTGGTVTLSVDRQTQAGQAGTLITVADTGPGIAPEHQQRLFERFY
RGSNPTESGSGLGLAIVRELLALMGGTISVASTVGQGSQFTCWLPLEQHTHTA

Sequences:

>Translated_533_residues
MAANEPGQVTSPEDSYQRLRTEYERLQLLYSLAQQFATMLSLPNVLQHVLSATTRFTNAVRGSIFLYGEYDEVQMHLLSE
RFQQARLTPFTNRILREGLASWVLKHRQSALIADTNLDERWIDYPSDTLDVRSVLCVPLLRGRRVRGVLTLVHPEIGFFT
MDDEALLNVIAQHAAMAIENAQLIADINDERRKFEGAFTAMEEGLILVDGDGRIHFVNPQALAFFAVTPPVPEHLNELSQ
QVLGLFKEAQQTGDSVRAEIVLEQNPTTDLAIHIAYIPIFSEQEDWWTIVLHDITRLKEYDRLKTQFVANASHELRTPLA
NIKLYARLAQQVKAKTKLPQYLETIASEAGRLEAIVEDLLTLTRLDSGLMHSSPEWVDIIELLRNLAQTYRPLAEAREQR
LIFQECTSNLPKLWLAPDQFMRVVVNLLSNALKFTPTGGTVTLSVDRQTQAGQAGTLITVADTGPGIAPEHQQRLFERFY
RGSNPTESGSGLGLAIVRELLALMGGTISVASTVGQGSQFTCWLPLEQHTHTA
>Mature_532_residues
AANEPGQVTSPEDSYQRLRTEYERLQLLYSLAQQFATMLSLPNVLQHVLSATTRFTNAVRGSIFLYGEYDEVQMHLLSER
FQQARLTPFTNRILREGLASWVLKHRQSALIADTNLDERWIDYPSDTLDVRSVLCVPLLRGRRVRGVLTLVHPEIGFFTM
DDEALLNVIAQHAAMAIENAQLIADINDERRKFEGAFTAMEEGLILVDGDGRIHFVNPQALAFFAVTPPVPEHLNELSQQ
VLGLFKEAQQTGDSVRAEIVLEQNPTTDLAIHIAYIPIFSEQEDWWTIVLHDITRLKEYDRLKTQFVANASHELRTPLAN
IKLYARLAQQVKAKTKLPQYLETIASEAGRLEAIVEDLLTLTRLDSGLMHSSPEWVDIIELLRNLAQTYRPLAEAREQRL
IFQECTSNLPKLWLAPDQFMRVVVNLLSNALKFTPTGGTVTLSVDRQTQAGQAGTLITVADTGPGIAPEHQQRLFERFYR
GSNPTESGSGLGLAIVRELLALMGGTISVASTVGQGSQFTCWLPLEQHTHTA

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=355, Percent_Identity=28.4507042253521, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788713, Length=269, Percent_Identity=30.8550185873606, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI1786783, Length=246, Percent_Identity=32.1138211382114, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=32.7731092436975, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1788393, Length=238, Percent_Identity=33.1932773109244, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI145693157, Length=227, Percent_Identity=33.920704845815, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1789149, Length=233, Percent_Identity=31.3304721030043, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1790346, Length=250, Percent_Identity=28, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI48994928, Length=246, Percent_Identity=32.1138211382114, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787894, Length=234, Percent_Identity=31.1965811965812, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790300, Length=360, Percent_Identity=24.4444444444444, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1790861, Length=212, Percent_Identity=30.6603773584906, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=27.8260869565217, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081816, Length=226, Percent_Identity=32.7433628318584, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1789808, Length=237, Percent_Identity=28.6919831223629, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788549, Length=236, Percent_Identity=26.6949152542373, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789403, Length=213, Percent_Identity=31.4553990610329, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI87082128, Length=243, Percent_Identity=27.9835390946502, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788279, Length=219, Percent_Identity=26.9406392694064, Blast_Score=72, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6322044, Length=74, Percent_Identity=47.2972972972973, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59817; Mature: 59686

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAANEPGQVTSPEDSYQRLRTEYERLQLLYSLAQQFATMLSLPNVLQHVLSATTRFTNAV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGSIFLYGEYDEVQMHLLSERFQQARLTPFTNRILREGLASWVLKHRQSALIADTNLDER
CCCEEEEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHH
WIDYPSDTLDVRSVLCVPLLRGRRVRGVLTLVHPEIGFFTMDDEALLNVIAQHAAMAIEN
HCCCCCCHHHHHHHHHHHHHCCCCHHEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHCC
AQLIADINDERRKFEGAFTAMEEGLILVDGDGRIHFVNPQALAFFAVTPPVPEHLNELSQ
CHHEECCCHHHHHHHHHHHHHHCCEEEEECCCEEEEECCCEEEEEEECCCCHHHHHHHHH
QVLGLFKEAQQTGDSVRAEIVLEQNPTTDLAIHIAYIPIFSEQEDWWTIVLHDITRLKEY
HHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEEEEEEECCCCCCEEHHHHHHHHHHHH
DRLKTQFVANASHELRTPLANIKLYARLAQQVKAKTKLPQYLETIASEAGRLEAIVEDLL
HHHHHHHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHH
TLTRLDSGLMHSSPEWVDIIELLRNLAQTYRPLAEAREQRLIFQECTSNLPKLWLAPDQF
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHH
MRVVVNLLSNALKFTPTGGTVTLSVDRQTQAGQAGTLITVADTGPGIAPEHQQRLFERFY
HHHHHHHHHHHHEECCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHH
RGSNPTESGSGLGLAIVRELLALMGGTISVASTVGQGSQFTCWLPLEQHTHTA
CCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCEEEEEEECHHCCCCC
>Mature Secondary Structure 
AANEPGQVTSPEDSYQRLRTEYERLQLLYSLAQQFATMLSLPNVLQHVLSATTRFTNAV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGSIFLYGEYDEVQMHLLSERFQQARLTPFTNRILREGLASWVLKHRQSALIADTNLDER
CCCEEEEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHH
WIDYPSDTLDVRSVLCVPLLRGRRVRGVLTLVHPEIGFFTMDDEALLNVIAQHAAMAIEN
HCCCCCCHHHHHHHHHHHHHCCCCHHEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHCC
AQLIADINDERRKFEGAFTAMEEGLILVDGDGRIHFVNPQALAFFAVTPPVPEHLNELSQ
CHHEECCCHHHHHHHHHHHHHHCCEEEEECCCEEEEECCCEEEEEEECCCCHHHHHHHHH
QVLGLFKEAQQTGDSVRAEIVLEQNPTTDLAIHIAYIPIFSEQEDWWTIVLHDITRLKEY
HHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEEEEEEECCCCCCEEHHHHHHHHHHHH
DRLKTQFVANASHELRTPLANIKLYARLAQQVKAKTKLPQYLETIASEAGRLEAIVEDLL
HHHHHHHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHH
TLTRLDSGLMHSSPEWVDIIELLRNLAQTYRPLAEAREQRLIFQECTSNLPKLWLAPDQF
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHH
MRVVVNLLSNALKFTPTGGTVTLSVDRQTQAGQAGTLITVADTGPGIAPEHQQRLFERFY
HHHHHHHHHHHHEECCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHH
RGSNPTESGSGLGLAIVRELLALMGGTISVASTVGQGSQFTCWLPLEQHTHTA
CCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCEEEEEEECHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]