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The map label for this gene is typA [H]

Identifier: 159901087

GI number: 159901087

Start: 5854575

End: 5856398

Strand: Reverse

Name: typA [H]

Synonym: Haur_4575

Alternate gene names: 159901087

Gene position: 5856398-5854575 (Counterclockwise)

Preceding gene: 159901088

Following gene: 159901085

Centisome position: 92.28

GC content: 52.14

Gene sequence:

>1824_bases
ATGCAACGAACTGATTTACGCAATATCGCAATTATTGCCCACGTTGACCACGGCAAGACGACCTTGGTTGATGCCATGTT
GAAGCAAAGTCGGATTTTCCGTGATAACCAACAAGTCGCTGAACGGGTGATGGACTCCAACGCCATCGAACGCGAACGTG
GGATCACGATTATGGCCAAAAATACCGCTGTTGAATATAACGGCGTGCGGATTAATATTGTCGATACGCCAGGCCACGCC
GATTTCGGTGGCGAGGTTGAGCGGGTTTTGAACATGGTCGATGGCGTGTTGCTGTTGGTCGATGCGGTTGAAGGCCCAAT
GCCCCAAACCAAGTTCGTGCTGCGCAAAGCTCTCGAACAAGGCCACCGCGCGATTGTCGTCGTCAACAAAGTCGATCGCC
CGAGCGCTCGCCCCAATTATGTGGTCAACGAAACCTTCGATTTATTCATCGACTTGGGCGCAACCGAAGAACAAGCTGAA
TTCCCAATTGTTTATGCCAGCGGGATTGCTGGCACAGCTGGCCACGACCCTCACGCGATGCAAGATTCGCTGACCCCACT
GTTTGAAACGATTTTGCAATATGTGCCCGCCCCCGATGTTGATGCCCATGGCCCGCCGCAATTGCTGGTCACTTCAACCA
TGTACGACGATTACAAAGGCAAAATCATCATTGGCCGTTTGAACAGCGGAACCATTCGTAAAGGTCAAGCGGTTGCTCAC
ATCGCCGCAGGCAAAGATCCCAAGCCTGCCAAAGTGGTGCAAGTGTTCACCCACTATGGCATGGAACGGGTCGAAGTCGA
TGAAATCACTGCTGGCGATATCGTCGCCATGACTGGGATCAACGACGCTGGGATTGGCGATACGATTGCCGATAAAGATA
ATCCAGTCGCCTTGCCACCAATCAAGGTCGAAGAACCAACCGTTCAGATGACCTTCGGCGTGAATACCAGCCCCTTCAGC
GGTCGCGAAGGCAAATTGGTAACCTCACGCAAAATTCGCGAACGCTTATATGGCGAAACCGAGCGCGACGTGGCCTTGAA
GGTCGAAGATACCGACAACGCCGATACCTTCCGCGTCAGCGGTCGCGGTGAGTTGCACTTGGCAATTTTGATCGAAAATA
TGCGGCGCGAAGGCTATGAGTTCCAAGTCTCTAAAGCCGAAGTGATTTATAAAGATATTGATGGCACACGCCACGAGCCA
TATGAATTGGTCGAAATCGAAGTTGATTCCGATTATCAAGGCTCGGTCGTCGAATTGATGGGCTTGCGCCGTGGCACCAT
GCGCGACATGAGTGTTAGCGATTCAGGTTCGGTGCAATTCGTCTATCACGTGCCAACCCGTGGTTTGTTGGGCTTCCGTC
AACAATTGCTCACCGCAACTCGGGGCACAGGCATTATGAACAGCTTGTTTGCTGGCTATCAACCTTACGCTGGCGATGTG
CAAACACGCCAATTTGGCTCGTTGATTGCTTGGGAACAAGGCGTAACCAGCAGCTATGGCTTGTCGAGCGCCCAAGAACG
CGGCCAATTATTTGTTGGCTCAGGCGTTGATGTGTACGAAGGCATGATCATTGGCCAACACATTCGTGACGAAGACCTTG
AAGTCAATGCCTGTAAGAAAAAGCAACTGACCAATATGCGTTCATCAGGTGCTGACGATGCCTTGCGCCTCGACGTACCA
CGCAACATGTCGCTCGACGATTGTATCGAATACCTTGCCGACGATGAATTGCTCGAAGTAACTCCGCTGCATTTCCGGCT
CCGCAAGCGTATCCTCAACACCGACGAACGCCGCCGCGATCGCAAATGGGCCAAAAATCGCTAA

Upstream 100 bases:

>100_bases
AACCTTGCGAACGAATTAACGAAACAACGTGTGGTACAATAGCCATGCTGACGTTTGAATGAGCTACCTCGGCCCCTGTG
GTCGAGGTTTTTGGTGTGTT

Downstream 100 bases:

>100_bases
ATTTGATTAGCAATCAACTCCCTTGCTCAGTTCTTTGGGCAAGGGAGTTATTTTTAATCGAGAATCGAAATTTAAGTATT
ACCCTCACTCCCTAACCTTT

Product: GTP-binding protein TypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MQRTDLRNIAIIAHVDHGKTTLVDAMLKQSRIFRDNQQVAERVMDSNAIERERGITIMAKNTAVEYNGVRINIVDTPGHA
DFGGEVERVLNMVDGVLLLVDAVEGPMPQTKFVLRKALEQGHRAIVVVNKVDRPSARPNYVVNETFDLFIDLGATEEQAE
FPIVYASGIAGTAGHDPHAMQDSLTPLFETILQYVPAPDVDAHGPPQLLVTSTMYDDYKGKIIIGRLNSGTIRKGQAVAH
IAAGKDPKPAKVVQVFTHYGMERVEVDEITAGDIVAMTGINDAGIGDTIADKDNPVALPPIKVEEPTVQMTFGVNTSPFS
GREGKLVTSRKIRERLYGETERDVALKVEDTDNADTFRVSGRGELHLAILIENMRREGYEFQVSKAEVIYKDIDGTRHEP
YELVEIEVDSDYQGSVVELMGLRRGTMRDMSVSDSGSVQFVYHVPTRGLLGFRQQLLTATRGTGIMNSLFAGYQPYAGDV
QTRQFGSLIAWEQGVTSSYGLSSAQERGQLFVGSGVDVYEGMIIGQHIRDEDLEVNACKKKQLTNMRSSGADDALRLDVP
RNMSLDDCIEYLADDELLEVTPLHFRLRKRILNTDERRRDRKWAKNR

Sequences:

>Translated_607_residues
MQRTDLRNIAIIAHVDHGKTTLVDAMLKQSRIFRDNQQVAERVMDSNAIERERGITIMAKNTAVEYNGVRINIVDTPGHA
DFGGEVERVLNMVDGVLLLVDAVEGPMPQTKFVLRKALEQGHRAIVVVNKVDRPSARPNYVVNETFDLFIDLGATEEQAE
FPIVYASGIAGTAGHDPHAMQDSLTPLFETILQYVPAPDVDAHGPPQLLVTSTMYDDYKGKIIIGRLNSGTIRKGQAVAH
IAAGKDPKPAKVVQVFTHYGMERVEVDEITAGDIVAMTGINDAGIGDTIADKDNPVALPPIKVEEPTVQMTFGVNTSPFS
GREGKLVTSRKIRERLYGETERDVALKVEDTDNADTFRVSGRGELHLAILIENMRREGYEFQVSKAEVIYKDIDGTRHEP
YELVEIEVDSDYQGSVVELMGLRRGTMRDMSVSDSGSVQFVYHVPTRGLLGFRQQLLTATRGTGIMNSLFAGYQPYAGDV
QTRQFGSLIAWEQGVTSSYGLSSAQERGQLFVGSGVDVYEGMIIGQHIRDEDLEVNACKKKQLTNMRSSGADDALRLDVP
RNMSLDDCIEYLADDELLEVTPLHFRLRKRILNTDERRRDRKWAKNR
>Mature_607_residues
MQRTDLRNIAIIAHVDHGKTTLVDAMLKQSRIFRDNQQVAERVMDSNAIERERGITIMAKNTAVEYNGVRINIVDTPGHA
DFGGEVERVLNMVDGVLLLVDAVEGPMPQTKFVLRKALEQGHRAIVVVNKVDRPSARPNYVVNETFDLFIDLGATEEQAE
FPIVYASGIAGTAGHDPHAMQDSLTPLFETILQYVPAPDVDAHGPPQLLVTSTMYDDYKGKIIIGRLNSGTIRKGQAVAH
IAAGKDPKPAKVVQVFTHYGMERVEVDEITAGDIVAMTGINDAGIGDTIADKDNPVALPPIKVEEPTVQMTFGVNTSPFS
GREGKLVTSRKIRERLYGETERDVALKVEDTDNADTFRVSGRGELHLAILIENMRREGYEFQVSKAEVIYKDIDGTRHEP
YELVEIEVDSDYQGSVVELMGLRRGTMRDMSVSDSGSVQFVYHVPTRGLLGFRQQLLTATRGTGIMNSLFAGYQPYAGDV
QTRQFGSLIAWEQGVTSSYGLSSAQERGQLFVGSGVDVYEGMIIGQHIRDEDLEVNACKKKQLTNMRSSGADDALRLDVP
RNMSLDDCIEYLADDELLEVTPLHFRLRKRILNTDERRRDRKWAKNR

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=512, Percent_Identity=27.9296875, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI94966754, Length=133, Percent_Identity=42.1052631578947, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI34147630, Length=272, Percent_Identity=30.8823529411765, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI4503483, Length=148, Percent_Identity=35.1351351351351, Blast_Score=101, Evalue=3e-21,
Organism=Homo sapiens, GI18390331, Length=138, Percent_Identity=41.304347826087, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI19923640, Length=139, Percent_Identity=40.2877697841727, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI25306283, Length=139, Percent_Identity=40.2877697841727, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI25306287, Length=139, Percent_Identity=40.2877697841727, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI310132016, Length=112, Percent_Identity=38.3928571428571, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI310110807, Length=112, Percent_Identity=38.3928571428571, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI310123363, Length=112, Percent_Identity=38.3928571428571, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI217272892, Length=136, Percent_Identity=33.8235294117647, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI217272894, Length=136, Percent_Identity=33.8235294117647, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI53729339, Length=277, Percent_Identity=28.8808664259928, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI53729337, Length=277, Percent_Identity=28.8808664259928, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI94966752, Length=129, Percent_Identity=32.5581395348837, Blast_Score=76, Evalue=1e-13,
Organism=Escherichia coli, GI48994988, Length=602, Percent_Identity=53.8205980066445, Blast_Score=654, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=503, Percent_Identity=30.6163021868787, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1789738, Length=150, Percent_Identity=40, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1790835, Length=144, Percent_Identity=29.8611111111111, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790412, Length=235, Percent_Identity=28.0851063829787, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789737, Length=235, Percent_Identity=28.0851063829787, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789559, Length=232, Percent_Identity=29.3103448275862, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17557151, Length=323, Percent_Identity=31.2693498452012, Blast_Score=136, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI71988811, Length=128, Percent_Identity=38.28125, Blast_Score=108, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI71988819, Length=128, Percent_Identity=38.28125, Blast_Score=108, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17506493, Length=178, Percent_Identity=33.1460674157303, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17556745, Length=135, Percent_Identity=40, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17533571, Length=138, Percent_Identity=41.304347826087, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17556456, Length=279, Percent_Identity=28.3154121863799, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17552882, Length=134, Percent_Identity=33.5820895522388, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25141371, Length=294, Percent_Identity=26.8707482993197, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71994658, Length=131, Percent_Identity=36.6412213740458, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323320, Length=512, Percent_Identity=27.34375, Blast_Score=141, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6324707, Length=148, Percent_Identity=40.5405405405405, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320593, Length=148, Percent_Identity=40.5405405405405, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6324761, Length=270, Percent_Identity=31.4814814814815, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6322359, Length=150, Percent_Identity=36.6666666666667, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323098, Length=175, Percent_Identity=34.8571428571429, Blast_Score=91, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6324166, Length=142, Percent_Identity=36.6197183098592, Blast_Score=84, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6324550, Length=235, Percent_Identity=24.6808510638298, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI78706572, Length=511, Percent_Identity=26.027397260274, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24585709, Length=154, Percent_Identity=36.3636363636364, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24585711, Length=154, Percent_Identity=36.3636363636364, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24585713, Length=154, Percent_Identity=36.3636363636364, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28574573, Length=141, Percent_Identity=38.2978723404255, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24582462, Length=144, Percent_Identity=38.8888888888889, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21357743, Length=134, Percent_Identity=36.5671641791045, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI281363316, Length=244, Percent_Identity=27.4590163934426, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI17864358, Length=244, Percent_Identity=27.4590163934426, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI19921738, Length=237, Percent_Identity=28.6919831223629, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221458488, Length=146, Percent_Identity=40.4109589041096, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28572034, Length=284, Percent_Identity=28.8732394366197, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 67477; Mature: 67477

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRTDLRNIAIIAHVDHGKTTLVDAMLKQSRIFRDNQQVAERVMDSNAIERERGITIMAK
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHCCEEEEEE
NTAVEYNGVRINIVDTPGHADFGGEVERVLNMVDGVLLLVDAVEGPMPQTKFVLRKALEQ
CCEEEECCEEEEEEECCCCCCCCHHHHHHHHHHHHHHEEEEHHCCCCCHHHHHHHHHHHC
GHRAIVVVNKVDRPSARPNYVVNETFDLFIDLGATEEQAEFPIVYASGIAGTAGHDPHAM
CCEEEEEEECCCCCCCCCCEEECCCEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCHH
QDSLTPLFETILQYVPAPDVDAHGPPQLLVTSTMYDDYKGKIIIGRLNSGTIRKGQAVAH
HHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCEEEE
IAAGKDPKPAKVVQVFTHYGMERVEVDEITAGDIVAMTGINDAGIGDTIADKDNPVALPP
EECCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCEECCC
IKVEEPTVQMTFGVNTSPFSGREGKLVTSRKIRERLYGETERDVALKVEDTDNADTFRVS
EECCCCEEEEEECCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEC
GRGELHLAILIENMRREGYEFQVSKAEVIYKDIDGTRHEPYELVEIEVDSDYQGSVVELM
CCCCEEEEEEEEHHHCCCCEEEEECCEEEEECCCCCCCCCEEEEEEEECCCCCCCHHHHH
GLRRGTMRDMSVSDSGSVQFVYHVPTRGLLGFRQQLLTATRGTGIMNSLFAGYQPYAGDV
HCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCC
QTRQFGSLIAWEQGVTSSYGLSSAQERGQLFVGSGVDVYEGMIIGQHIRDEDLEVNACKK
CHHHHCCCHHHHCCCCCCCCCCCHHHCCCEEEECCCHHHCCEEEECCCCCCCCCCCHHHH
KQLTNMRSSGADDALRLDVPRNMSLDDCIEYLADDELLEVTPLHFRLRKRILNTDERRRD
HHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHCCCCEEEECHHHHHHHHHHHCCHHHHHH
RKWAKNR
HHHCCCC
>Mature Secondary Structure
MQRTDLRNIAIIAHVDHGKTTLVDAMLKQSRIFRDNQQVAERVMDSNAIERERGITIMAK
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHCCEEEEEE
NTAVEYNGVRINIVDTPGHADFGGEVERVLNMVDGVLLLVDAVEGPMPQTKFVLRKALEQ
CCEEEECCEEEEEEECCCCCCCCHHHHHHHHHHHHHHEEEEHHCCCCCHHHHHHHHHHHC
GHRAIVVVNKVDRPSARPNYVVNETFDLFIDLGATEEQAEFPIVYASGIAGTAGHDPHAM
CCEEEEEEECCCCCCCCCCEEECCCEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCHH
QDSLTPLFETILQYVPAPDVDAHGPPQLLVTSTMYDDYKGKIIIGRLNSGTIRKGQAVAH
HHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCEEEE
IAAGKDPKPAKVVQVFTHYGMERVEVDEITAGDIVAMTGINDAGIGDTIADKDNPVALPP
EECCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCEECCC
IKVEEPTVQMTFGVNTSPFSGREGKLVTSRKIRERLYGETERDVALKVEDTDNADTFRVS
EECCCCEEEEEECCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEC
GRGELHLAILIENMRREGYEFQVSKAEVIYKDIDGTRHEPYELVEIEVDSDYQGSVVELM
CCCCEEEEEEEEHHHCCCCEEEEECCEEEEECCCCCCCCCEEEEEEEECCCCCCCHHHHH
GLRRGTMRDMSVSDSGSVQFVYHVPTRGLLGFRQQLLTATRGTGIMNSLFAGYQPYAGDV
HCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCC
QTRQFGSLIAWEQGVTSSYGLSSAQERGQLFVGSGVDVYEGMIIGQHIRDEDLEVNACKK
CHHHHCCCHHHHCCCCCCCCCCCHHHCCCEEEECCCHHHCCEEEECCCCCCCCCCCHHHH
KQLTNMRSSGADDALRLDVPRNMSLDDCIEYLADDELLEVTPLHFRLRKRILNTDERRRD
HHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHCCCCEEEECHHHHHHHHHHHCCHHHHHH
RKWAKNR
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]