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The map label for this gene is sucC

Identifier: 159901081

GI number: 159901081

Start: 5846600

End: 5847736

Strand: Reverse

Name: sucC

Synonym: Haur_4569

Alternate gene names: 159901081

Gene position: 5847736-5846600 (Counterclockwise)

Preceding gene: 159901082

Following gene: 159901079

Centisome position: 92.14

GC content: 50.92

Gene sequence:

>1137_bases
ATGAAGCTCCACGAATACCAAGCCCGTGATATCGTGGCTCGTTATGGCATTCCAGTAACAGGCGGCGGTGTTGCTGCGAC
GGCGGAAGAAGTTCAAAAAGTTGCCGAGCAAATTGGCGGCCCAGTGGCAGTCAAGGCGCAAGTGCATGTTGGCGGTCGGG
GCAAAGCTGGCGGGATCAAGTTGGCCAACACGCCAGCCGAAGCCTTCGATGCTGGCAAAGCCATTTTAGGCATGGATATC
AAAGGCCTGACGGTTGAAAAAGTGCTGGTAGCCGAAGCGATCACCTTTGAAAAAGAAATTTACCTTGGGGTGATTTTGGA
TCGTGCGACCAAGCGAGTTGTGCTGATTGCTTCATCAGAGGGTGGCGTTGAAATCGAAGAAGTCGCCAAAATCAATCCTG
ATGCAATCATCAAATTGGCAGCTGACCCCTTACTTGGCTTGCAACCCTACCAAGCTCAAGAATTGGCCTATAGCATTGGC
ATAACCGATGCTAAGCAAGCTCGCCAATTTTCAAGCATCGCAACCGGTTTGTATCGGGCATTTGTCGAAAACGATGCTGA
ATTAGCCGAAATCAACCCCTTGGTGGTGTTGCCAAACGGCCAATTGCAAGCCCTCGACTCGAAAATTGTGCTTGATGATA
GCGGTTTGTTCCGCCACAGCGAAGTTGCGGGCATGCGCGATATCGCAGGCGAGCCAGAATCAGAAATCAAAGCTCGCGAA
AATGGTCTGACCTTTATCAAGCTCGATGGCAATATTGGCTGTATGGTCAATGGCGCAGGCTTGGCAATGGCCACCATGGA
CGTGGTAAATCTGTTCGGCGGCGAACCAGCCAACTTCCTTGACATCGGTGGTGGGGCTAACGCCCAAAAAGTCGCCGCAG
CCCTTGATATTATTCTTGATGATCCCAATGTTAAAGTTGTCATGGTCAATATCTTTGGTGGCATCACCCGCTGCGATGAA
GTTGCCAAGGGGATTGTCGAAGCCCAAAAAATCATCAAGCGTCAAGTGCCAATGGTCGTGCGCTTGGTTGGCACCAACGA
AGCCGAAGGCCAACGCATTTTGGCTGATGCCAGCTTAACTCCAGCTTCAACCTTGGCCGACGCAGCCCAAAAAGCTGTTG
ATATTGCCAAACAATAA

Upstream 100 bases:

>100_bases
ATTTACTTTGACTTCTCTAGATGAGCCTGATACCATGCCCAAGGGCTAAACACCTCTGTTTAGCCATCTTGATTGATGCA
TTTACTCGTGCGGAGGTGCA

Downstream 100 bases:

>100_bases
TTTAGCTAAGTTGGGCTAACATCGCCTGAATCAATTGGCGTTCATGCAGATCAACACAATTGCGGTGGAGTTGTTCTAAG
TTGGTTTGCCAATGCAGTAG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MKLHEYQARDIVARYGIPVTGGGVAATAEEVQKVAEQIGGPVAVKAQVHVGGRGKAGGIKLANTPAEAFDAGKAILGMDI
KGLTVEKVLVAEAITFEKEIYLGVILDRATKRVVLIASSEGGVEIEEVAKINPDAIIKLAADPLLGLQPYQAQELAYSIG
ITDAKQARQFSSIATGLYRAFVENDAELAEINPLVVLPNGQLQALDSKIVLDDSGLFRHSEVAGMRDIAGEPESEIKARE
NGLTFIKLDGNIGCMVNGAGLAMATMDVVNLFGGEPANFLDIGGGANAQKVAAALDIILDDPNVKVVMVNIFGGITRCDE
VAKGIVEAQKIIKRQVPMVVRLVGTNEAEGQRILADASLTPASTLADAAQKAVDIAKQ

Sequences:

>Translated_378_residues
MKLHEYQARDIVARYGIPVTGGGVAATAEEVQKVAEQIGGPVAVKAQVHVGGRGKAGGIKLANTPAEAFDAGKAILGMDI
KGLTVEKVLVAEAITFEKEIYLGVILDRATKRVVLIASSEGGVEIEEVAKINPDAIIKLAADPLLGLQPYQAQELAYSIG
ITDAKQARQFSSIATGLYRAFVENDAELAEINPLVVLPNGQLQALDSKIVLDDSGLFRHSEVAGMRDIAGEPESEIKARE
NGLTFIKLDGNIGCMVNGAGLAMATMDVVNLFGGEPANFLDIGGGANAQKVAAALDIILDDPNVKVVMVNIFGGITRCDE
VAKGIVEAQKIIKRQVPMVVRLVGTNEAEGQRILADASLTPASTLADAAQKAVDIAKQ
>Mature_378_residues
MKLHEYQARDIVARYGIPVTGGGVAATAEEVQKVAEQIGGPVAVKAQVHVGGRGKAGGIKLANTPAEAFDAGKAILGMDI
KGLTVEKVLVAEAITFEKEIYLGVILDRATKRVVLIASSEGGVEIEEVAKINPDAIIKLAADPLLGLQPYQAQELAYSIG
ITDAKQARQFSSIATGLYRAFVENDAELAEINPLVVLPNGQLQALDSKIVLDDSGLFRHSEVAGMRDIAGEPESEIKARE
NGLTFIKLDGNIGCMVNGAGLAMATMDVVNLFGGEPANFLDIGGGANAQKVAAALDIILDDPNVKVVMVNIFGGITRCDE
VAKGIVEAQKIIKRQVPMVVRLVGTNEAEGQRILADASLTPASTLADAAQKAVDIAKQ

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI157779135, Length=380, Percent_Identity=38.9473684210526, Blast_Score=258, Evalue=7e-69,
Organism=Homo sapiens, GI11321583, Length=394, Percent_Identity=38.3248730964467, Blast_Score=253, Evalue=1e-67,
Organism=Homo sapiens, GI294862256, Length=360, Percent_Identity=39.1666666666667, Blast_Score=247, Evalue=2e-65,
Organism=Escherichia coli, GI1786948, Length=383, Percent_Identity=49.0861618798956, Blast_Score=332, Evalue=3e-92,
Organism=Caenorhabditis elegans, GI17567829, Length=395, Percent_Identity=41.7721518987342, Blast_Score=280, Evalue=6e-76,
Organism=Caenorhabditis elegans, GI17539378, Length=400, Percent_Identity=36.75, Blast_Score=239, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6321683, Length=397, Percent_Identity=39.2947103274559, Blast_Score=278, Evalue=1e-75,
Organism=Drosophila melanogaster, GI161078106, Length=401, Percent_Identity=39.1521197007481, Blast_Score=250, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24645208, Length=401, Percent_Identity=39.1521197007481, Blast_Score=250, Evalue=1e-66,
Organism=Drosophila melanogaster, GI281361397, Length=402, Percent_Identity=39.3034825870647, Blast_Score=249, Evalue=2e-66,
Organism=Drosophila melanogaster, GI281361395, Length=402, Percent_Identity=39.3034825870647, Blast_Score=249, Evalue=2e-66,
Organism=Drosophila melanogaster, GI21356231, Length=394, Percent_Identity=37.8172588832487, Blast_Score=237, Evalue=8e-63,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_HERA2 (A9B0I2)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001547328.1
- ProteinModelPortal:   A9B0I2
- SMR:   A9B0I2
- GeneID:   5736414
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_4569
- HOGENOM:   HBG315432
- OMA:   NPLIVMK
- ProtClustDB:   PRK00696
- BioCyc:   HAUR316274:HAUR_4569-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 39640; Mature: 39640

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLHEYQARDIVARYGIPVTGGGVAATAEEVQKVAEQIGGPVAVKAQVHVGGRGKAGGIK
CCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCEE
LANTPAEAFDAGKAILGMDIKGLTVEKVLVAEAITFEKEIYLGVILDRATKRVVLIASSE
EECCCHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHEEEEEEEECCCCEEEEEECCC
GGVEIEEVAKINPDAIIKLAADPLLGLQPYQAQELAYSIGITDAKQARQFSSIATGLYRA
CCEEHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHEEEECCCCHHHHHHHHHHHHHHHHH
FVENDAELAEINPLVVLPNGQLQALDSKIVLDDSGLFRHSEVAGMRDIAGEPESEIKARE
HHCCCCCEECCCCEEEECCCCEEECCCEEEEECCCCEEHHHHCCHHHHCCCCHHHHHHHH
NGLTFIKLDGNIGCMVNGAGLAMATMDVVNLFGGEPANFLDIGGGANAQKVAAALDIILD
CCEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHEEEEEEC
DPNVKVVMVNIFGGITRCDEVAKGIVEAQKIIKRQVPMVVRLVGTNEAEGQRILADASLT
CCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEECCCCC
PASTLADAAQKAVDIAKQ
CHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLHEYQARDIVARYGIPVTGGGVAATAEEVQKVAEQIGGPVAVKAQVHVGGRGKAGGIK
CCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCEE
LANTPAEAFDAGKAILGMDIKGLTVEKVLVAEAITFEKEIYLGVILDRATKRVVLIASSE
EECCCHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHEEEEEEEECCCCEEEEEECCC
GGVEIEEVAKINPDAIIKLAADPLLGLQPYQAQELAYSIGITDAKQARQFSSIATGLYRA
CCEEHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHEEEECCCCHHHHHHHHHHHHHHHHH
FVENDAELAEINPLVVLPNGQLQALDSKIVLDDSGLFRHSEVAGMRDIAGEPESEIKARE
HHCCCCCEECCCCEEEECCCCEEECCCEEEEECCCCEEHHHHCCHHHHCCCCHHHHHHHH
NGLTFIKLDGNIGCMVNGAGLAMATMDVVNLFGGEPANFLDIGGGANAQKVAAALDIILD
CCEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHEEEEEEC
DPNVKVVMVNIFGGITRCDEVAKGIVEAQKIIKRQVPMVVRLVGTNEAEGQRILADASLT
CCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEECCCCC
PASTLADAAQKAVDIAKQ
CHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA