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The map label for this gene is sucD [H]

Identifier: 159901078

GI number: 159901078

Start: 5843962

End: 5844843

Strand: Reverse

Name: sucD [H]

Synonym: Haur_4566

Alternate gene names: 159901078

Gene position: 5844843-5843962 (Counterclockwise)

Preceding gene: 159901079

Following gene: 159901073

Centisome position: 92.09

GC content: 53.97

Gene sequence:

>882_bases
TTGAGTATTTTGGCTGATAAAAATACCCGCCTGATTGTGCAGGGGATTACAGGCCGCGAAGGTGAGTTTCATTCGCGCCA
AATGCTGGAATATGGCACAAATTTGGTCGGTGGGGTTACACCTGGTCGCGGCGGCCAAAAAGCCGTTGATGGCCGTGTGC
CTGTGTTCAACACGGTCAAGCAAGCCGTCAAAGAAACTGGCGCAAACGCTACGGTAATTTATGTGCCCGCTGCGTTTGCT
CCTGATGCCGTCCGCGAGGCCGCTGATGCAGGCATTCCGTTGATCGTTTGTATTACTGAAGGCGTGCCAGCGCTGGATAT
GGTGGCAACCTATGAGTTTGTTAAGCTCAAAGGTTCACGCTTGATCGGGCCAAACTGCCCGGGCTTGCTGACCCCCGGCG
AAGCCAAATTGGGAATTATCCCCGGCTCAATCGCCAAACCAGGCCCAGTTGGCGTGGTCTCAAAATCAGGTACATTGACC
TATGAAGCGGTCGATGCCTTGACCCGCATTGGCCTTGGCCAAACCTCAATCGTCGGGATTGGTGGCGACCCAATTATCGG
CACCAACTTCATCGATGTTTTGGCGATGTTCCAAGCCGACCCAGCCACCGAAGCGATTGTGTTGATCGGTGAAATTGGCG
GTAACGCTGAACAAGATGCCGCCGCCTTTATCAAGGAAAATGTCACCAAGCCAGTGGTCTCGTTTATTGCTGGTCAATCG
GCCCCTCCAGGCAAGCGCATGGGCCATGCTGGCGCAATTATCGGCGCTGGTGGCGAAGGCACTGCCCAAGAAAAAATCGA
AGCCTTGGAAGCAGTTGGCGCGAAAGTTGCCAAATTGCCCACCGATATCGCGAAATTGGTCGCCGAAAGCCTTGGCAAAT
AA

Upstream 100 bases:

>100_bases
TCATAGCCATTTTGCCTTTTGACTTTTGCCCTTTGATTTTCAGTGTCATTTTGCCTTTTGACTTTTGCCTTTTGATTTTC
TGTCAAGGAGGACATTTCCA

Downstream 100 bases:

>100_bases
GCCAATTGATTGGCACGAAAAAACCACTCCAATTGCTGGAGTGGTTTTTTTGTTTGCGATACCAAAAGCCCGCTGAAGCT
GATTAACCTTTTACCCCGCC

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSILADKNTRLIVQGITGREGEFHSRQMLEYGTNLVGGVTPGRGGQKAVDGRVPVFNTVKQAVKETGANATVIYVPAAFA
PDAVREAADAGIPLIVCITEGVPALDMVATYEFVKLKGSRLIGPNCPGLLTPGEAKLGIIPGSIAKPGPVGVVSKSGTLT
YEAVDALTRIGLGQTSIVGIGGDPIIGTNFIDVLAMFQADPATEAIVLIGEIGGNAEQDAAAFIKENVTKPVVSFIAGQS
APPGKRMGHAGAIIGAGGEGTAQEKIEALEAVGAKVAKLPTDIAKLVAESLGK

Sequences:

>Translated_293_residues
MSILADKNTRLIVQGITGREGEFHSRQMLEYGTNLVGGVTPGRGGQKAVDGRVPVFNTVKQAVKETGANATVIYVPAAFA
PDAVREAADAGIPLIVCITEGVPALDMVATYEFVKLKGSRLIGPNCPGLLTPGEAKLGIIPGSIAKPGPVGVVSKSGTLT
YEAVDALTRIGLGQTSIVGIGGDPIIGTNFIDVLAMFQADPATEAIVLIGEIGGNAEQDAAAFIKENVTKPVVSFIAGQS
APPGKRMGHAGAIIGAGGEGTAQEKIEALEAVGAKVAKLPTDIAKLVAESLGK
>Mature_292_residues
SILADKNTRLIVQGITGREGEFHSRQMLEYGTNLVGGVTPGRGGQKAVDGRVPVFNTVKQAVKETGANATVIYVPAAFAP
DAVREAADAGIPLIVCITEGVPALDMVATYEFVKLKGSRLIGPNCPGLLTPGEAKLGIIPGSIAKPGPVGVVSKSGTLTY
EAVDALTRIGLGQTSIVGIGGDPIIGTNFIDVLAMFQADPATEAIVLIGEIGGNAEQDAAAFIKENVTKPVVSFIAGQSA
PPGKRMGHAGAIIGAGGEGTAQEKIEALEAVGAKVAKLPTDIAKLVAESLGK

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=297, Percent_Identity=56.5656565656566, Blast_Score=283, Evalue=1e-76,
Organism=Homo sapiens, GI38569421, Length=313, Percent_Identity=28.7539936102236, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI38569423, Length=313, Percent_Identity=28.7539936102236, Blast_Score=90, Evalue=2e-18,
Organism=Escherichia coli, GI1786949, Length=291, Percent_Identity=62.1993127147766, Blast_Score=354, Evalue=4e-99,
Organism=Caenorhabditis elegans, GI17553126, Length=295, Percent_Identity=56.271186440678, Blast_Score=294, Evalue=3e-80,
Organism=Caenorhabditis elegans, GI17550194, Length=294, Percent_Identity=54.7619047619048, Blast_Score=291, Evalue=3e-79,
Organism=Caenorhabditis elegans, GI17557344, Length=261, Percent_Identity=30.2681992337165, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17551266, Length=261, Percent_Identity=30.2681992337165, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324716, Length=301, Percent_Identity=45.514950166113, Blast_Score=248, Evalue=9e-67,
Organism=Drosophila melanogaster, GI21356559, Length=291, Percent_Identity=49.8281786941581, Blast_Score=280, Evalue=8e-76,
Organism=Drosophila melanogaster, GI28574296, Length=281, Percent_Identity=56.5836298932384, Blast_Score=266, Evalue=1e-71,
Organism=Drosophila melanogaster, GI281363477, Length=312, Percent_Identity=28.525641025641, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281363475, Length=312, Percent_Identity=28.525641025641, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI281363473, Length=312, Percent_Identity=28.525641025641, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 29787; Mature: 29656

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILADKNTRLIVQGITGREGEFHSRQMLEYGTNLVGGVTPGRGGQKAVDGRVPVFNTVK
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
QAVKETGANATVIYVPAAFAPDAVREAADAGIPLIVCITEGVPALDMVATYEFVKLKGSR
HHHHHCCCCEEEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHEEECCCE
LIGPNCPGLLTPGEAKLGIIPGSIAKPGPVGVVSKSGTLTYEAVDALTRIGLGQTSIVGI
EECCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCEEHHHHHHHHHHCCCCCEEEEC
GGDPIIGTNFIDVLAMFQADPATEAIVLIGEIGGNAEQDAAAFIKENVTKPVVSFIAGQS
CCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCC
APPGKRMGHAGAIIGAGGEGTAQEKIEALEAVGAKVAKLPTDIAKLVAESLGK
CCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SILADKNTRLIVQGITGREGEFHSRQMLEYGTNLVGGVTPGRGGQKAVDGRVPVFNTVK
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
QAVKETGANATVIYVPAAFAPDAVREAADAGIPLIVCITEGVPALDMVATYEFVKLKGSR
HHHHHCCCCEEEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHEEECCCE
LIGPNCPGLLTPGEAKLGIIPGSIAKPGPVGVVSKSGTLTYEAVDALTRIGLGQTSIVGI
EECCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCEEHHHHHHHHHHCCCCCEEEEC
GGDPIIGTNFIDVLAMFQADPATEAIVLIGEIGGNAEQDAAAFIKENVTKPVVSFIAGQS
CCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCC
APPGKRMGHAGAIIGAGGEGTAQEKIEALEAVGAKVAKLPTDIAKLVAESLGK
CCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]