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The map label for this gene is pleC [H]

Identifier: 159900917

GI number: 159900917

Start: 5627289

End: 5628782

Strand: Reverse

Name: pleC [H]

Synonym: Haur_4404

Alternate gene names: 159900917

Gene position: 5628782-5627289 (Counterclockwise)

Preceding gene: 159900918

Following gene: 159900916

Centisome position: 88.69

GC content: 50.33

Gene sequence:

>1494_bases
ATGGAAGAACACGATCAAATCGATGCCAGCCTTCAGGAAAATCTCTTATCGTTTCGGATCGACACCCTCACGATTTTAGT
GTATTTGTGCTTGGGGTTTGGCGTGCTTTGGTTCGCTATGCTGCTAACCCAAGTTACCAGCAATGCAGGCGATTATACCC
GTAGCGGCCCGCCGTGGGTGCTCTTTGCTGTTGGCACAGGCATGGCTTTTATGGGCCTGCGCTACAACAAAATTCGCTTG
GCACGAAGTGCTTTCTTCTTTTCAATTGTCGGCACACCAACGATTAGCCTCTTTTTGCTGCCTGGCACAACTCAATTTAT
GAGCTACTCGCTAGTGTTGGCGGTGATTATCGCGGGGATTTTGTATTCGCCTCGCGCCCCATTCACCGTTGTTGCACTTG
TAGTGGTTATCTTCTTAATGGTTGGAATGGCCTCGGCAACCAATTTTACCAATCACTATGGCTCAATTACTCAATTTATC
ACTACCTTTACGCCGCCTTCAGTCACGTTGCTGTTGGCAGCGCTTACCAGTTGGCTAGCAACCCGCGACTTGGTAGCAAC
CGTCGAATGGGCCATGGAAAGCCATCGTTTAGCCGAACGCCGCGCCGAACGCCTGCGGGTCAGTGAAGCACGGGTTGCCC
GTACCTTGCTTGAGCTTGAGGGCGCTTATGAAATGCAATCGCGCTTGAATAGCCAGTTACAAGTTCTTAACAAAGAGCTA
GAGGTAGCACGGACTGCCGCCGATGAGGCTAATACATTAAAAACTCGCTTCTTAGCCAATATGTCGCACGAGCTGCGCAC
GCCACTCAATGCGATCATCAACTTTACCCAGTTTTTGGGCAAACCCCGCTATGGCGATTTGACTGCCCGCCAAATTGAGC
TGCAAGAACGGGTCTTAGTCAATAGCGAGCATCTGCTTGGCCTAATCAACGATATCTTAGATCTCTCGAAGATCGAAGCC
GGACGCATGGAATTGCACCTTGAGCTGCTTGATTTGCAGCCAATTTTCAATGGGGTTATGGCAACAGCGGTTGGCTTGAC
CAAGAGCAAAGGCTTAAACCTCGAATCAGATGTTGAGGAAGAAATTCCGCCTGTACGTGGCGATAAAGTGCGGGTACGCC
AGATTTTGCTCAATTTGCTTTCCAACGCTGCCAAATTTACCGACAGCGGCGGCATTACGCTCCGCGCCTTCGAGAGCGAT
GGGATGGTACAAATTTCAGTCATCGATACTGGCGCAGGTATTCCGGCTCACGAATTGCCCTTGGTTTTTGAAGAATTTCA
CCAAGTTGAGCAAGCCGCCTCAGCCCAACGCCAACAAGGCACCGGCTTGGGCTTGCCAATTAGCCGCCACTTGGTAGAAT
TACAGGGCGGCACCATGTGGGCCGAAAGTCAATTTGGCAGTGGCTCAAGTTTTAGTTTCACCCTGCCAATTGCTGAAAAT
CTTACGCCCGAAGTCGTTATTTTCGACCCACAAACGAAACAGACAGCGCTATGA

Upstream 100 bases:

>100_bases
AATCTGATGCACAATAATTGCAAAAACATGGTATGATTTTGAGCCATAATCAATCAATTGTTCAGCAAGCATATTAATTC
AACTGAATGGTGGCCCCACC

Downstream 100 bases:

>100_bases
TTGACCCAAACTTTGCCCATGTGCTGGTTGTTGAAGACCGTGATGATACCTTTTTCGTGGTGCAAGATCTGCTGATCACT
GAAATTGGGGTTCGCTCGTG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MEEHDQIDASLQENLLSFRIDTLTILVYLCLGFGVLWFAMLLTQVTSNAGDYTRSGPPWVLFAVGTGMAFMGLRYNKIRL
ARSAFFFSIVGTPTISLFLLPGTTQFMSYSLVLAVIIAGILYSPRAPFTVVALVVVIFLMVGMASATNFTNHYGSITQFI
TTFTPPSVTLLLAALTSWLATRDLVATVEWAMESHRLAERRAERLRVSEARVARTLLELEGAYEMQSRLNSQLQVLNKEL
EVARTAADEANTLKTRFLANMSHELRTPLNAIINFTQFLGKPRYGDLTARQIELQERVLVNSEHLLGLINDILDLSKIEA
GRMELHLELLDLQPIFNGVMATAVGLTKSKGLNLESDVEEEIPPVRGDKVRVRQILLNLLSNAAKFTDSGGITLRAFESD
GMVQISVIDTGAGIPAHELPLVFEEFHQVEQAASAQRQQGTGLGLPISRHLVELQGGTMWAESQFGSGSSFSFTLPIAEN
LTPEVVIFDPQTKQTAL

Sequences:

>Translated_497_residues
MEEHDQIDASLQENLLSFRIDTLTILVYLCLGFGVLWFAMLLTQVTSNAGDYTRSGPPWVLFAVGTGMAFMGLRYNKIRL
ARSAFFFSIVGTPTISLFLLPGTTQFMSYSLVLAVIIAGILYSPRAPFTVVALVVVIFLMVGMASATNFTNHYGSITQFI
TTFTPPSVTLLLAALTSWLATRDLVATVEWAMESHRLAERRAERLRVSEARVARTLLELEGAYEMQSRLNSQLQVLNKEL
EVARTAADEANTLKTRFLANMSHELRTPLNAIINFTQFLGKPRYGDLTARQIELQERVLVNSEHLLGLINDILDLSKIEA
GRMELHLELLDLQPIFNGVMATAVGLTKSKGLNLESDVEEEIPPVRGDKVRVRQILLNLLSNAAKFTDSGGITLRAFESD
GMVQISVIDTGAGIPAHELPLVFEEFHQVEQAASAQRQQGTGLGLPISRHLVELQGGTMWAESQFGSGSSFSFTLPIAEN
LTPEVVIFDPQTKQTAL
>Mature_497_residues
MEEHDQIDASLQENLLSFRIDTLTILVYLCLGFGVLWFAMLLTQVTSNAGDYTRSGPPWVLFAVGTGMAFMGLRYNKIRL
ARSAFFFSIVGTPTISLFLLPGTTQFMSYSLVLAVIIAGILYSPRAPFTVVALVVVIFLMVGMASATNFTNHYGSITQFI
TTFTPPSVTLLLAALTSWLATRDLVATVEWAMESHRLAERRAERLRVSEARVARTLLELEGAYEMQSRLNSQLQVLNKEL
EVARTAADEANTLKTRFLANMSHELRTPLNAIINFTQFLGKPRYGDLTARQIELQERVLVNSEHLLGLINDILDLSKIEA
GRMELHLELLDLQPIFNGVMATAVGLTKSKGLNLESDVEEEIPPVRGDKVRVRQILLNLLSNAAKFTDSGGITLRAFESD
GMVQISVIDTGAGIPAHELPLVFEEFHQVEQAASAQRQQGTGLGLPISRHLVELQGGTMWAESQFGSGSSFSFTLPIAEN
LTPEVVIFDPQTKQTAL

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=271, Percent_Identity=37.2693726937269, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI145693157, Length=244, Percent_Identity=36.4754098360656, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI87081816, Length=260, Percent_Identity=36.5384615384615, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI48994928, Length=241, Percent_Identity=35.6846473029046, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI1788713, Length=246, Percent_Identity=32.9268292682927, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI87082128, Length=231, Percent_Identity=30.7359307359307, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=30.3418803418803, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786600, Length=248, Percent_Identity=31.4516129032258, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786912, Length=253, Percent_Identity=29.6442687747036, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788393, Length=259, Percent_Identity=27.7992277992278, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786783, Length=231, Percent_Identity=30.7359307359307, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788549, Length=301, Percent_Identity=25.2491694352159, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790861, Length=229, Percent_Identity=28.82096069869, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=233, Percent_Identity=26.1802575107296, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787894, Length=240, Percent_Identity=25.8333333333333, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54821; Mature: 54821

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEHDQIDASLQENLLSFRIDTLTILVYLCLGFGVLWFAMLLTQVTSNAGDYTRSGPPWV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
LFAVGTGMAFMGLRYNKIRLARSAFFFSIVGTPTISLFLLPGTTQFMSYSLVLAVIIAGI
EEEECCCHHHHCCCHHHHHHHHHHHHEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHH
LYSPRAPFTVVALVVVIFLMVGMASATNFTNHYGSITQFITTFTPPSVTLLLAALTSWLA
HCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TRDLVATVEWAMESHRLAERRAERLRVSEARVARTLLELEGAYEMQSRLNSQLQVLNKEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
EVARTAADEANTLKTRFLANMSHELRTPLNAIINFTQFLGKPRYGDLTARQIELQERVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
NSEHLLGLINDILDLSKIEAGRMELHLELLDLQPIFNGVMATAVGLTKSKGLNLESDVEE
CCHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
EIPPVRGDKVRVRQILLNLLSNAAKFTDSGGITLRAFESDGMVQISVIDTGAGIPAHELP
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEECCCCCCHHHHH
LVFEEFHQVEQAASAQRQQGTGLGLPISRHLVELQGGTMWAESQFGSGSSFSFTLPIAEN
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEECCCEEEECCCCCCCCCEEEEECHHCC
LTPEVVIFDPQTKQTAL
CCCCEEEECCCCCCCCC
>Mature Secondary Structure
MEEHDQIDASLQENLLSFRIDTLTILVYLCLGFGVLWFAMLLTQVTSNAGDYTRSGPPWV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
LFAVGTGMAFMGLRYNKIRLARSAFFFSIVGTPTISLFLLPGTTQFMSYSLVLAVIIAGI
EEEECCCHHHHCCCHHHHHHHHHHHHEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHH
LYSPRAPFTVVALVVVIFLMVGMASATNFTNHYGSITQFITTFTPPSVTLLLAALTSWLA
HCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TRDLVATVEWAMESHRLAERRAERLRVSEARVARTLLELEGAYEMQSRLNSQLQVLNKEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
EVARTAADEANTLKTRFLANMSHELRTPLNAIINFTQFLGKPRYGDLTARQIELQERVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
NSEHLLGLINDILDLSKIEAGRMELHLELLDLQPIFNGVMATAVGLTKSKGLNLESDVEE
CCHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
EIPPVRGDKVRVRQILLNLLSNAAKFTDSGGITLRAFESDGMVQISVIDTGAGIPAHELP
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEECCCCCCHHHHH
LVFEEFHQVEQAASAQRQQGTGLGLPISRHLVELQGGTMWAESQFGSGSSFSFTLPIAEN
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEECCCEEEECCCCCCCCCEEEEECHHCC
LTPEVVIFDPQTKQTAL
CCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]