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The map label for this gene is yfhQ [H]

Identifier: 159900913

GI number: 159900913

Start: 5624162

End: 5625133

Strand: Reverse

Name: yfhQ [H]

Synonym: Haur_4400

Alternate gene names: 159900913

Gene position: 5625133-5624162 (Counterclockwise)

Preceding gene: 159900915

Following gene: 159900908

Centisome position: 88.63

GC content: 52.26

Gene sequence:

>972_bases
ATGAGCGAATTAAGTACCTTACAAATCGATCTGCTAGCGTGGTTTCAAGCCAATGGCCGCGATTTACCATGGCGACGCAC
CCGTAATCCTTACTATATTTTGGTGTCGGAAACCATGCTGCAACAAACCCAAGTTGATCGGGTGATTCCCAAATATGAGG
CATTTTTGGCCCTATTTCCGACGGTCGAGGCCTTGGCTAGTGCTTCAACCGCCGATGTCATTCGTTCGTGGCAAGGCTTG
GGCTACAATCGTCGCGCGGTCAATCTGCAACGGGCGGCCCAAGCAATTGTCGCAGCAGGCTATCCCGCCGATCCTGCTGG
TTTCCCCGCTACACCCGAGGGTTTGCGCAATTTGCCAGGGATTGGAGCTTACACCTCGGGGGCGGTCGCATGTTTTGCCT
TCGAGCGTGATGTGGCCTTTCTTGATACTAATATTCGGCGTGTGGTACGACGTTTGTTGGTCGGCCCCGAAGATGCTCCG
CCTGAAACCAATGAACAAACGTTGATCGATTATGCCCAACAATTAATTCCCCAAGGCCAAGGCTGGGCATGGAACCAAGC
AATTATGGAATTGGGAGCGTTAATTTGTAGTGCCGCCAAACCTCAATGCTGGCGTTGCCCAGTCAATCAACATTGCCGAG
CCTACGCGATTTGGCGCGAAGCCAACACGCAGCTTGATATGTGGCAACCACCAGTGATCAAACCACGCAAAAAGGCTGCC
GAACAACCATTTCATACATCAAACCGCTATTTTCGTGGGCGCATTATCGATGCCCTGCGAGCACTCGAAACCCAGCAAAG
CCTTGATCTGGCTAGTTTGGGGCCACAAGTCAAGCCAGATTGGGTCGGCAATGAGCATGATCTCACATGGCTAGCCAAGT
TGGTCAATGGTTTGGCCCAAGATGGCTTGCTGATTTGGCAGCAGCAACCAGAGCAGCAATTAGCCGAGTGGAGTGTGCGA
CTACCAGCTTAA

Upstream 100 bases:

>100_bases
GCACAGTTGTGCGTGATCGAGCGACTAAAGACCGAGATTTGAGCCATGCCCGTTAGTTTATGGTACGATCAAGCTAGAAC
GTTTTAGAACAGAAAGCATT

Downstream 100 bases:

>100_bases
CCAAGGTGAAGGACTCGCTACGAGACGTTGCGAAACTATTTCGTTGCTGCTGGGTAAATACCTGTATTCTAAACCCATAA
ACAAACGAGGCCAAGTGAAC

Product: HhH-GPD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MSELSTLQIDLLAWFQANGRDLPWRRTRNPYYILVSETMLQQTQVDRVIPKYEAFLALFPTVEALASASTADVIRSWQGL
GYNRRAVNLQRAAQAIVAAGYPADPAGFPATPEGLRNLPGIGAYTSGAVACFAFERDVAFLDTNIRRVVRRLLVGPEDAP
PETNEQTLIDYAQQLIPQGQGWAWNQAIMELGALICSAAKPQCWRCPVNQHCRAYAIWREANTQLDMWQPPVIKPRKKAA
EQPFHTSNRYFRGRIIDALRALETQQSLDLASLGPQVKPDWVGNEHDLTWLAKLVNGLAQDGLLIWQQQPEQQLAEWSVR
LPA

Sequences:

>Translated_323_residues
MSELSTLQIDLLAWFQANGRDLPWRRTRNPYYILVSETMLQQTQVDRVIPKYEAFLALFPTVEALASASTADVIRSWQGL
GYNRRAVNLQRAAQAIVAAGYPADPAGFPATPEGLRNLPGIGAYTSGAVACFAFERDVAFLDTNIRRVVRRLLVGPEDAP
PETNEQTLIDYAQQLIPQGQGWAWNQAIMELGALICSAAKPQCWRCPVNQHCRAYAIWREANTQLDMWQPPVIKPRKKAA
EQPFHTSNRYFRGRIIDALRALETQQSLDLASLGPQVKPDWVGNEHDLTWLAKLVNGLAQDGLLIWQQQPEQQLAEWSVR
LPA
>Mature_322_residues
SELSTLQIDLLAWFQANGRDLPWRRTRNPYYILVSETMLQQTQVDRVIPKYEAFLALFPTVEALASASTADVIRSWQGLG
YNRRAVNLQRAAQAIVAAGYPADPAGFPATPEGLRNLPGIGAYTSGAVACFAFERDVAFLDTNIRRVVRRLLVGPEDAPP
ETNEQTLIDYAQQLIPQGQGWAWNQAIMELGALICSAAKPQCWRCPVNQHCRAYAIWREANTQLDMWQPPVIKPRKKAAE
QPFHTSNRYFRGRIIDALRALETQQSLDLASLGPQVKPDWVGNEHDLTWLAKLVNGLAQDGLLIWQQQPEQQLAEWSVRL
PA

Specific function: Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine, 8- oxo-dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal effici

COG id: COG1194

COG function: function code L; A/G-specific DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HhH domain [H]

Homologues:

Organism=Homo sapiens, GI115298654, Length=225, Percent_Identity=39.5555555555556, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI115298652, Length=225, Percent_Identity=39.5555555555556, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI115298648, Length=225, Percent_Identity=39.5555555555556, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI115298650, Length=225, Percent_Identity=39.5555555555556, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI6912520, Length=225, Percent_Identity=39.5555555555556, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI190358497, Length=225, Percent_Identity=39.5555555555556, Blast_Score=146, Evalue=3e-35,
Organism=Escherichia coli, GI1789331, Length=213, Percent_Identity=38.9671361502347, Blast_Score=147, Evalue=8e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003651
- InterPro:   IPR003265
- InterPro:   IPR023170
- InterPro:   IPR005760
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: 3.2.2.-

Molecular weight: Translated: 36299; Mature: 36168

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELSTLQIDLLAWFQANGRDLPWRRTRNPYYILVSETMLQQTQVDRVIPKYEAFLALFP
CCCCHHEEEHHHEEECCCCCCCCCEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
TVEALASASTADVIRSWQGLGYNRRAVNLQRAAQAIVAAGYPADPAGFPATPEGLRNLPG
HHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCC
IGAYTSGAVACFAFERDVAFLDTNIRRVVRRLLVGPEDAPPETNEQTLIDYAQQLIPQGQ
CCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCC
GWAWNQAIMELGALICSAAKPQCWRCPVNQHCRAYAIWREANTQLDMWQPPVIKPRKKAA
CCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHH
EQPFHTSNRYFRGRIIDALRALETQQSLDLASLGPQVKPDWVGNEHDLTWLAKLVNGLAQ
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
DGLLIWQQQPEQQLAEWSVRLPA
CCEEEECCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
SELSTLQIDLLAWFQANGRDLPWRRTRNPYYILVSETMLQQTQVDRVIPKYEAFLALFP
CCCHHEEEHHHEEECCCCCCCCCEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
TVEALASASTADVIRSWQGLGYNRRAVNLQRAAQAIVAAGYPADPAGFPATPEGLRNLPG
HHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCC
IGAYTSGAVACFAFERDVAFLDTNIRRVVRRLLVGPEDAPPETNEQTLIDYAQQLIPQGQ
CCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCC
GWAWNQAIMELGALICSAAKPQCWRCPVNQHCRAYAIWREANTQLDMWQPPVIKPRKKAA
CCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHH
EQPFHTSNRYFRGRIIDALRALETQQSLDLASLGPQVKPDWVGNEHDLTWLAKLVNGLAQ
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
DGLLIWQQQPEQQLAEWSVRLPA
CCEEEECCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: 4Fe-4S Cluster [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Glycosylases; Hydrolysing N-glycosyl compounds [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]