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The map label for this gene is iap [H]

Identifier: 159900897

GI number: 159900897

Start: 5599779

End: 5601449

Strand: Reverse

Name: iap [H]

Synonym: Haur_4384

Alternate gene names: 159900897

Gene position: 5601449-5599779 (Counterclockwise)

Preceding gene: 159900898

Following gene: 159900896

Centisome position: 88.26

GC content: 52.48

Gene sequence:

>1671_bases
ATGCAAGATGCTAAGTCCTCGAATGATCTGATCCAAGAAGATCATGATCTGCAAGACTTCCAGCAGCGGGCTGTGAACAA
CGAAAATTCGCTTTTACGAACGACCAGTTTACGCCAGCGCGTTAACGCCCGTTCGGTTTCTGCACTTCGTGCGGTTCCAT
CGTACCTGCGCAAAGCTCCACGGCGCTACCTACTTCATCTTATGGTGCTTTCGCTCTTACCAGTTGGTTTAGTTGTCAAC
AAAGATGCCACTAAGCCTCAGGTAGATACTGCACTCTTGGTCAGCGCATCGCCAACTGCTGAACGCCAAGTTCGGCCAGC
ACTCGGCTTGATGACCATGACCCACCGCAACGAACCAGCTCCGTTGACTGCTCTCAATGATTCAGAAGCTACGCCTGACC
CAGGTGTTGGCGATGGGCCAATTAGCAGCCCCGATTTTGATGATTCGTTGGTGATTCCAGTAGGCCGCCCAGTTAATAAC
AACCCGACCTATCCCGAATCAGTAGTGAGCGCCGATATTGCCAACTTGCGCAATGGCCCAAGCACTGAATTCGATCGTCT
CGATAAATTAGAACCAGGCACCAAGGTAACCGTTGTGGCTCGCCACGCCGATTGGGTGCAAGTGCGCACCGAAGGCGGCC
AAGAAGGTTGGCTCGCCGCTGATTTGCTTGATTTAGAGCAATCGGTGATCGATGCTTTGCCTGATGCCCAAAATATTCCA
ACCCCACCACCAGCCAAAGTGGGCAAGATCACCCAAGATAATTTGAACTTGCGTGATGGCCCTGGTACTGACTACATCAG
CATGAAAAAGCTGGGAATTGATAGCCAAGTTTCATTGTTGGCCCGCTATCAAGGCTGGTATCAAATTGAAACTGGTGAAG
GTAATGTGGGTTGGGTTTCAGCCGAATTCTTGAATCTTGAAGCTGGCGTTGCCGAACGGATCGCCGAAGCTGAATCGATT
CCATCAGCTAACCCCGATTTGGTCGGTTGGGCAACTGATGAAGGCATCAACTTGCGCTCTGGCCCAAGCACCAAATTCGA
TTCATTGGGCAAACTGAGCAAAGGCGCTGAATTAACCTTATTAGCTCGTTACAAAGAATGGGTCAAGGTTCAAACCGCCA
AAGGTACCAAAGGCTGGATCTCACAAGATTTAGTTGATGTCAGCAACTTTGTGTTCCGCCGTGTACCATTCACAACCAAT
GTGCCCTCATTACCAGTTGCTCCAGCTGCCCCCAAAAAGAGCACTCCTAGCCAACCTGCTGGTGGCGGTGGCGGCGGTGG
TGGTACTGCTAGCGGCGACGTTGCTTCGATGGCTTGGGCCTATGTTGGCTACAACTATCGCTGGGGCGGCGAAAGCCCAA
GCAGCGGCTTCGATTGCAGCGGCTTGACCAAGTATTTGTATCGCCAAGTTGGGGTCAGCTTGCCCCACAGTGCCGCTGGC
CAATATAGCAGCGCTTATGGCACCTTCATCGGAAGCATGAGCAACTTGCAACCAGGCGATTTGCTGTTCTATGCTGGCAC
TGCTGGCCCGGGCATCACCCACGTAGGCATCTACGTTGGCGGTGGTGTGATGGTCAATGCGATGACTCCCGCTTCGGGGG
TTGGTGCAGTCAGCATCTATAGCAGCTACTGGCTCAATCACTATTACGGCGCGTTGCGGCCTTATCGCTAG

Upstream 100 bases:

>100_bases
TAACTTCGCTCTCGGCATTGCACGATGCATAAACGTTAATTATTTAATTGTCGGTGCGATATCATTAAGCCGCATTCGAT
AATAGGGAGGTTACAGCTGC

Downstream 100 bases:

>100_bases
TTGCTGTTTCATACACCTGTTCAATGCAAGAAGCGTTCCACAAATTGTGGGACGCTTCTTTTGTTTTTTGGCTTAATCTC
GGCTACTATAATCGCGCGTA

Product: NLP/P60 protein

Products: NA

Alternate protein names: Invasion-associated protein [H]

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MQDAKSSNDLIQEDHDLQDFQQRAVNNENSLLRTTSLRQRVNARSVSALRAVPSYLRKAPRRYLLHLMVLSLLPVGLVVN
KDATKPQVDTALLVSASPTAERQVRPALGLMTMTHRNEPAPLTALNDSEATPDPGVGDGPISSPDFDDSLVIPVGRPVNN
NPTYPESVVSADIANLRNGPSTEFDRLDKLEPGTKVTVVARHADWVQVRTEGGQEGWLAADLLDLEQSVIDALPDAQNIP
TPPPAKVGKITQDNLNLRDGPGTDYISMKKLGIDSQVSLLARYQGWYQIETGEGNVGWVSAEFLNLEAGVAERIAEAESI
PSANPDLVGWATDEGINLRSGPSTKFDSLGKLSKGAELTLLARYKEWVKVQTAKGTKGWISQDLVDVSNFVFRRVPFTTN
VPSLPVAPAAPKKSTPSQPAGGGGGGGGTASGDVASMAWAYVGYNYRWGGESPSSGFDCSGLTKYLYRQVGVSLPHSAAG
QYSSAYGTFIGSMSNLQPGDLLFYAGTAGPGITHVGIYVGGGVMVNAMTPASGVGAVSIYSSYWLNHYYGALRPYR

Sequences:

>Translated_556_residues
MQDAKSSNDLIQEDHDLQDFQQRAVNNENSLLRTTSLRQRVNARSVSALRAVPSYLRKAPRRYLLHLMVLSLLPVGLVVN
KDATKPQVDTALLVSASPTAERQVRPALGLMTMTHRNEPAPLTALNDSEATPDPGVGDGPISSPDFDDSLVIPVGRPVNN
NPTYPESVVSADIANLRNGPSTEFDRLDKLEPGTKVTVVARHADWVQVRTEGGQEGWLAADLLDLEQSVIDALPDAQNIP
TPPPAKVGKITQDNLNLRDGPGTDYISMKKLGIDSQVSLLARYQGWYQIETGEGNVGWVSAEFLNLEAGVAERIAEAESI
PSANPDLVGWATDEGINLRSGPSTKFDSLGKLSKGAELTLLARYKEWVKVQTAKGTKGWISQDLVDVSNFVFRRVPFTTN
VPSLPVAPAAPKKSTPSQPAGGGGGGGGTASGDVASMAWAYVGYNYRWGGESPSSGFDCSGLTKYLYRQVGVSLPHSAAG
QYSSAYGTFIGSMSNLQPGDLLFYAGTAGPGITHVGIYVGGGVMVNAMTPASGVGAVSIYSSYWLNHYYGALRPYR
>Mature_556_residues
MQDAKSSNDLIQEDHDLQDFQQRAVNNENSLLRTTSLRQRVNARSVSALRAVPSYLRKAPRRYLLHLMVLSLLPVGLVVN
KDATKPQVDTALLVSASPTAERQVRPALGLMTMTHRNEPAPLTALNDSEATPDPGVGDGPISSPDFDDSLVIPVGRPVNN
NPTYPESVVSADIANLRNGPSTEFDRLDKLEPGTKVTVVARHADWVQVRTEGGQEGWLAADLLDLEQSVIDALPDAQNIP
TPPPAKVGKITQDNLNLRDGPGTDYISMKKLGIDSQVSLLARYQGWYQIETGEGNVGWVSAEFLNLEAGVAERIAEAESI
PSANPDLVGWATDEGINLRSGPSTKFDSLGKLSKGAELTLLARYKEWVKVQTAKGTKGWISQDLVDVSNFVFRRVPFTTN
VPSLPVAPAAPKKSTPSQPAGGGGGGGGTASGDVASMAWAYVGYNYRWGGESPSSGFDCSGLTKYLYRQVGVSLPHSAAG
QYSSAYGTFIGSMSNLQPGDLLFYAGTAGPGITHVGIYVGGGVMVNAMTPASGVGAVSIYSSYWLNHYYGALRPYR

Specific function: This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1787944, Length=114, Percent_Identity=40.3508771929825, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1786421, Length=113, Percent_Identity=31.858407079646, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788501, Length=113, Percent_Identity=42.4778761061947, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR003646
- InterPro:   IPR013247 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60; PF08239 SH3_3 [H]

EC number: NA

Molecular weight: Translated: 59431; Mature: 59431

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDAKSSNDLIQEDHDLQDFQQRAVNNENSLLRTTSLRQRVNARSVSALRAVPSYLRKAP
CCCCCCCCCHHHCCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRYLLHLMVLSLLPVGLVVNKDATKPQVDTALLVSASPTAERQVRPALGLMTMTHRNEPA
HHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHEEEECCCCCC
PLTALNDSEATPDPGVGDGPISSPDFDDSLVIPVGRPVNNNPTYPESVVSADIANLRNGP
CEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCC
STEFDRLDKLEPGTKVTVVARHADWVQVRTEGGQEGWLAADLLDLEQSVIDALPDAQNIP
CCHHHHHHCCCCCCEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
TPPPAKVGKITQDNLNLRDGPGTDYISMKKLGIDSQVSLLARYQGWYQIETGEGNVGWVS
CCCCHHCCCEECCCCCCCCCCCCCEEEHHHCCCCHHHHHHHHCCCCEEEECCCCCEEEEE
AEFLNLEAGVAERIAEAESIPSANPDLVGWATDEGINLRSGPSTKFDSLGKLSKGAELTL
EEEHCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCEEE
LARYKEWVKVQTAKGTKGWISQDLVDVSNFVFRRVPFTTNVPSLPVAPAAPKKSTPSQPA
EEHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
GGGGGGGGTASGDVASMAWAYVGYNYRWGGESPSSGFDCSGLTKYLYRQVGVSLPHSAAG
CCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCHHCC
QYSSAYGTFIGSMSNLQPGDLLFYAGTAGPGITHVGIYVGGGVMVNAMTPASGVGAVSIY
CCHHHHHHHHHCCCCCCCCCEEEECCCCCCCCEEEEEEECCCEEEEEECCCCCCCHHHHH
SSYWLNHYYGALRPYR
HHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQDAKSSNDLIQEDHDLQDFQQRAVNNENSLLRTTSLRQRVNARSVSALRAVPSYLRKAP
CCCCCCCCCHHHCCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRYLLHLMVLSLLPVGLVVNKDATKPQVDTALLVSASPTAERQVRPALGLMTMTHRNEPA
HHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHEEEECCCCCC
PLTALNDSEATPDPGVGDGPISSPDFDDSLVIPVGRPVNNNPTYPESVVSADIANLRNGP
CEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCC
STEFDRLDKLEPGTKVTVVARHADWVQVRTEGGQEGWLAADLLDLEQSVIDALPDAQNIP
CCHHHHHHCCCCCCEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
TPPPAKVGKITQDNLNLRDGPGTDYISMKKLGIDSQVSLLARYQGWYQIETGEGNVGWVS
CCCCHHCCCEECCCCCCCCCCCCCEEEHHHCCCCHHHHHHHHCCCCEEEECCCCCEEEEE
AEFLNLEAGVAERIAEAESIPSANPDLVGWATDEGINLRSGPSTKFDSLGKLSKGAELTL
EEEHCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCEEE
LARYKEWVKVQTAKGTKGWISQDLVDVSNFVFRRVPFTTNVPSLPVAPAAPKKSTPSQPA
EEHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
GGGGGGGGTASGDVASMAWAYVGYNYRWGGESPSSGFDCSGLTKYLYRQVGVSLPHSAAG
CCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCHHCC
QYSSAYGTFIGSMSNLQPGDLLFYAGTAGPGITHVGIYVGGGVMVNAMTPASGVGAVSIY
CCHHHHHHHHHCCCCCCCCCEEEECCCCCCCCEEEEEEECCCEEEEEECCCCCCCHHHHH
SSYWLNHYYGALRPYR
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2111287; 1459966; 11679669 [H]