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The map label for this gene is rsbU [H]

Identifier: 159900888

GI number: 159900888

Start: 5589214

End: 5590764

Strand: Direct

Name: rsbU [H]

Synonym: Haur_4375

Alternate gene names: 159900888

Gene position: 5589214-5590764 (Clockwise)

Preceding gene: 159900887

Following gene: 159900902

Centisome position: 88.07

GC content: 53.13

Gene sequence:

>1551_bases
ATGAATCGTGCTCGCCGCCATCGCGATGTGATTAGCATCAGCCTGTTGCTCTCGGTCATTACGATTGTGATGTACCTTGG
TGAGGGGCGTTGGGCGGCTGCGCCTGCGTTACGCTACCTCTATTTGATTCCAATCGCCCAAGCTGCGATGGGCTTTGGCT
TGATGGGCAGCATGGCCGTGGCGATTTTGGCTGATCTGCTGTTTGCGCCCTTGGTTGCCACGGCCTTGGCCAAATATGGG
ATGTTTGGTGCTCCTACAGTTGAAATTATTGTGACCCTCGTTTTGATGCCGGTCTTGGCCTATTTTGCGGGCAGCGGTTG
GGGTCGGCTTAGTCGCCAGCGCGAGCTTTATCAATTTTTGAGCCGCATGGGCGATTTATTTGGCCGTTCGCTACCCCGCG
ATCAACTGCTCGCCGAGATTTTGCAAGAGGGTGGCCTGCTGATCGATGCTCAGGGCGGCGAAATTATTTTGCTTGAGCAA
GGCCAAGCGCGAATTGCCGCTAGCTGGGGAATTGAAGCCCAAGCTACTGCCGCCTACCAAACCAGCCTCGCCGCCTATAT
TTTAAAACGCAATGAGCCATGGTCAGCCACCAGCCTCGAAAATAACAGCGATTTTCAGCGTGTCGGTTTTGGTCAACGGA
TTGACGCTGCCCTAGCTGTGCCATTACGCTTAGAAGGTAAGCCGATTGGCCTGTTGGCGTTTTATAATCGGCCTGGCGGG
TTTAGCAAACAAGAGCAAGCCACAGTCGAGGCTATGGGCAGCAAAGTCGAAGTTGTGCTAGAGAATTTTCGCCAAGTCGA
GGAGCGCTCTGAACGCGCCCGCTTGCAGCGCGAGTTTGATTTGGCGGCTGAGGTGCAGCAACGCTTTTTGCCCCAGCAAT
TACCAGCGATCAGCGGCTATGAAATTGCTGGTTTTACTCAGCCCGCCCGTGAGGTTGGCGGCGATTTTTTCAATGTGCTG
AGTTTGCCCGATGGCCGTTGGTATATCGCGGTTGGCGATGTGTCGGGCAAGGGCGTGGTTGGCGCATTTTTCATGGCCAT
CGCCATGAGCGTCATCGATTTACATTTGCAAGAGGGCCAATCAACCACCCAACTAAGCCTGGCCAATCGGCTTAATCCGT
TGTTTTATCGGCGGATGGCCCAGCAAAAAATCAATACAGGTTTGGCCTATGCCTTGCTTGATGCTAAAACTGGCCATATG
CAGTTAGGCAACGCTGGCTTGATTGCGCCGTTGCATGTGCGCAAAAATGGCGAATGCGATTATCTCGATTTGACCGGCTT
TCCCTTAGGTGCGGTTGCTCAGGCTGAATATAGCGAATCGGTGCTAGAGCTTCAGGCTGGTGAAAGTTTGATTTTTATCA
GCGATGGTGTGGTTGAAGCCGCCAACCATGATCGCGAATTATTTGGCTTGAATCGACTGCGCAACTTGATTAGTATGCTG
AGCCAGCGTCCGGCCTCGCAGTTGGTGAGCGAAATTATGAACGCCGCCAATCGCTGGAGCGACGGCCAATACCAAGATGA
TATGACCGTCGTGGTACTCCGTCGGATCTAA

Upstream 100 bases:

>100_bases
TGATTTCGATTGCAGCTTCGCTGCTGTTTCGGCGTTATCAAAGCGTCGTGCCAGGTTACCTTTGCAATATTGTGTTTAGT
TTTAGTGCAATTTTACGCGC

Downstream 100 bases:

>100_bases
TGTCCGCGATCTTCTTCTAAAGCTCGTTGTAATTCCTCAATCAAGCCCAAAGGTGCTAAACGAACTCCCAGCAAATTGCT
GACCTCAGCTGGATCGGCAC

Product: GAF sensor-containing protein serine phosphatase

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MNRARRHRDVISISLLLSVITIVMYLGEGRWAAAPALRYLYLIPIAQAAMGFGLMGSMAVAILADLLFAPLVATALAKYG
MFGAPTVEIIVTLVLMPVLAYFAGSGWGRLSRQRELYQFLSRMGDLFGRSLPRDQLLAEILQEGGLLIDAQGGEIILLEQ
GQARIAASWGIEAQATAAYQTSLAAYILKRNEPWSATSLENNSDFQRVGFGQRIDAALAVPLRLEGKPIGLLAFYNRPGG
FSKQEQATVEAMGSKVEVVLENFRQVEERSERARLQREFDLAAEVQQRFLPQQLPAISGYEIAGFTQPAREVGGDFFNVL
SLPDGRWYIAVGDVSGKGVVGAFFMAIAMSVIDLHLQEGQSTTQLSLANRLNPLFYRRMAQQKINTGLAYALLDAKTGHM
QLGNAGLIAPLHVRKNGECDYLDLTGFPLGAVAQAEYSESVLELQAGESLIFISDGVVEAANHDRELFGLNRLRNLISML
SQRPASQLVSEIMNAANRWSDGQYQDDMTVVVLRRI

Sequences:

>Translated_516_residues
MNRARRHRDVISISLLLSVITIVMYLGEGRWAAAPALRYLYLIPIAQAAMGFGLMGSMAVAILADLLFAPLVATALAKYG
MFGAPTVEIIVTLVLMPVLAYFAGSGWGRLSRQRELYQFLSRMGDLFGRSLPRDQLLAEILQEGGLLIDAQGGEIILLEQ
GQARIAASWGIEAQATAAYQTSLAAYILKRNEPWSATSLENNSDFQRVGFGQRIDAALAVPLRLEGKPIGLLAFYNRPGG
FSKQEQATVEAMGSKVEVVLENFRQVEERSERARLQREFDLAAEVQQRFLPQQLPAISGYEIAGFTQPAREVGGDFFNVL
SLPDGRWYIAVGDVSGKGVVGAFFMAIAMSVIDLHLQEGQSTTQLSLANRLNPLFYRRMAQQKINTGLAYALLDAKTGHM
QLGNAGLIAPLHVRKNGECDYLDLTGFPLGAVAQAEYSESVLELQAGESLIFISDGVVEAANHDRELFGLNRLRNLISML
SQRPASQLVSEIMNAANRWSDGQYQDDMTVVVLRRI
>Mature_516_residues
MNRARRHRDVISISLLLSVITIVMYLGEGRWAAAPALRYLYLIPIAQAAMGFGLMGSMAVAILADLLFAPLVATALAKYG
MFGAPTVEIIVTLVLMPVLAYFAGSGWGRLSRQRELYQFLSRMGDLFGRSLPRDQLLAEILQEGGLLIDAQGGEIILLEQ
GQARIAASWGIEAQATAAYQTSLAAYILKRNEPWSATSLENNSDFQRVGFGQRIDAALAVPLRLEGKPIGLLAFYNRPGG
FSKQEQATVEAMGSKVEVVLENFRQVEERSERARLQREFDLAAEVQQRFLPQQLPAISGYEIAGFTQPAREVGGDFFNVL
SLPDGRWYIAVGDVSGKGVVGAFFMAIAMSVIDLHLQEGQSTTQLSLANRLNPLFYRRMAQQKINTGLAYALLDAKTGHM
QLGNAGLIAPLHVRKNGECDYLDLTGFPLGAVAQAEYSESVLELQAGESLIFISDGVVEAANHDRELFGLNRLRNLISML
SQRPASQLVSEIMNAANRWSDGQYQDDMTVVVLRRI

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 56634; Mature: 56634

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRARRHRDVISISLLLSVITIVMYLGEGRWAAAPALRYLYLIPIAQAAMGFGLMGSMAV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AILADLLFAPLVATALAKYGMFGAPTVEIIVTLVLMPVLAYFAGSGWGRLSRQRELYQFL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
SRMGDLFGRSLPRDQLLAEILQEGGLLIDAQGGEIILLEQGQARIAASWGIEAQATAAYQ
HHHHHHHCCCCCHHHHHHHHHHHCCEEEECCCCEEEEECCCCCEEEEECCCCCHHHHHHH
TSLAAYILKRNEPWSATSLENNSDFQRVGFGQRIDAALAVPLRLEGKPIGLLAFYNRPGG
HHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCHHEEEEEEECCCCEEEEEEECCCCC
FSKQEQATVEAMGSKVEVVLENFRQVEERSERARLQREFDLAAEVQQRFLPQQLPAISGY
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCC
EIAGFTQPAREVGGDFFNVLSLPDGRWYIAVGDVSGKGVVGAFFMAIAMSVIDLHLQEGQ
EECCCCCHHHHHCCHHEEHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCC
STTQLSLANRLNPLFYRRMAQQKINTGLAYALLDAKTGHMQLGNAGLIAPLHVRKNGECD
CHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCEEEEEECCCCCCC
YLDLTGFPLGAVAQAEYSESVLELQAGESLIFISDGVVEAANHDRELFGLNRLRNLISML
EEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHCCCCHHHHHHHHHHHHHHHH
SQRPASQLVSEIMNAANRWSDGQYQDDMTVVVLRRI
HCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MNRARRHRDVISISLLLSVITIVMYLGEGRWAAAPALRYLYLIPIAQAAMGFGLMGSMAV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AILADLLFAPLVATALAKYGMFGAPTVEIIVTLVLMPVLAYFAGSGWGRLSRQRELYQFL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
SRMGDLFGRSLPRDQLLAEILQEGGLLIDAQGGEIILLEQGQARIAASWGIEAQATAAYQ
HHHHHHHCCCCCHHHHHHHHHHHCCEEEECCCCEEEEECCCCCEEEEECCCCCHHHHHHH
TSLAAYILKRNEPWSATSLENNSDFQRVGFGQRIDAALAVPLRLEGKPIGLLAFYNRPGG
HHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCHHEEEEEEECCCCEEEEEEECCCCC
FSKQEQATVEAMGSKVEVVLENFRQVEERSERARLQREFDLAAEVQQRFLPQQLPAISGY
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCC
EIAGFTQPAREVGGDFFNVLSLPDGRWYIAVGDVSGKGVVGAFFMAIAMSVIDLHLQEGQ
EECCCCCHHHHHCCHHEEHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCC
STTQLSLANRLNPLFYRRMAQQKINTGLAYALLDAKTGHMQLGNAGLIAPLHVRKNGECD
CHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCEEEEEECCCCCCC
YLDLTGFPLGAVAQAEYSESVLELQAGESLIFISDGVVEAANHDRELFGLNRLRNLISML
EEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHCCCCHHHHHHHHHHHHHHHH
SQRPASQLVSEIMNAANRWSDGQYQDDMTVVVLRRI
HCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]