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The map label for this gene is ubiE [H]

Identifier: 159900843

GI number: 159900843

Start: 5529230

End: 5529940

Strand: Reverse

Name: ubiE [H]

Synonym: Haur_4330

Alternate gene names: 159900843

Gene position: 5529940-5529230 (Counterclockwise)

Preceding gene: 159900844

Following gene: 159900840

Centisome position: 87.13

GC content: 52.04

Gene sequence:

>711_bases
ATGTCAGTTTTGCCACAATCCGATCAGAAGGCGGTCTATGTCAATGCCATGTTCACAGCAATTGCCCAACGCTATGATCT
GATGAATCGGCTGATGACGTTTGGGCTTGATCAAGGCTGGCGGCGTTGGGCAACCAAGCGGATCAAACAGCCGCAAGCGG
CGTGGGCTTTGGATGTTGGCTCGGGCACTGGCGATTTTCTGCCGATTTTGCAACAAGCCATGCCCCAGCTCAGCGTCGTT
GGGCTGGATTTTACCTTAGCGATGATGCAGGCTGGCCAAGCCAAACGCGAGCAAGATACGCTTGGCCATAGCTTTATCAA
CGGCGATGGTATGCACTTGCCCTTCGAGGATGAAGCATTCGATATTGTGACGACAGGCTTTGCCATGCGCAATATTGTGG
ATATTCGCCAAGCATTTAGCGAGATGGCACGGGTAACCAAGCCAGGTGGCAAATTGGCCTGCTTAGAAGTTGCGCGGCCT
AAAAATCCCTTGGTACGTTGGGGGCATCAGTTCTATTTCAACAATATTGTGCCGATTATTGGCAGCCTTGTTGGCGGCAA
CAATCGCGCCTATACCTACTTGCCCCAATCAGCTTCGATCTTTCCGCAACCACCTGAGCTAGCCCAGATTATCGCCGAAT
GTGGCTGGCGCGATGTGACTTGGAAGCAACTTGGCTTTGGTGCAGTTGCCGTGCATATCGCTACGAAATAA

Upstream 100 bases:

>100_bases
CCGAGGTGGTCGATTTTGTGGCGGCTCGCGCCTTAGTCGCCTTGGGGCTAAGCCCTGAGCTTGATAGTAACCAGCAATGG
GCTGGCTTGGAGCTTGAATA

Downstream 100 bases:

>100_bases
TGTTGTGGGCAGCGATGTTTAAGTTCTCAGCAGCTTGAATTAAACAAAAACGCTGGATTCTTAGCGAATTCAGCGTTCTT
GGTGTTGTCTGCAAGGATAT

Product: ubiquinone/menaquinone biosynthesis methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSVLPQSDQKAVYVNAMFTAIAQRYDLMNRLMTFGLDQGWRRWATKRIKQPQAAWALDVGSGTGDFLPILQQAMPQLSVV
GLDFTLAMMQAGQAKREQDTLGHSFINGDGMHLPFEDEAFDIVTTGFAMRNIVDIRQAFSEMARVTKPGGKLACLEVARP
KNPLVRWGHQFYFNNIVPIIGSLVGGNNRAYTYLPQSASIFPQPPELAQIIAECGWRDVTWKQLGFGAVAVHIATK

Sequences:

>Translated_236_residues
MSVLPQSDQKAVYVNAMFTAIAQRYDLMNRLMTFGLDQGWRRWATKRIKQPQAAWALDVGSGTGDFLPILQQAMPQLSVV
GLDFTLAMMQAGQAKREQDTLGHSFINGDGMHLPFEDEAFDIVTTGFAMRNIVDIRQAFSEMARVTKPGGKLACLEVARP
KNPLVRWGHQFYFNNIVPIIGSLVGGNNRAYTYLPQSASIFPQPPELAQIIAECGWRDVTWKQLGFGAVAVHIATK
>Mature_235_residues
SVLPQSDQKAVYVNAMFTAIAQRYDLMNRLMTFGLDQGWRRWATKRIKQPQAAWALDVGSGTGDFLPILQQAMPQLSVVG
LDFTLAMMQAGQAKREQDTLGHSFINGDGMHLPFEDEAFDIVTTGFAMRNIVDIRQAFSEMARVTKPGGKLACLEVARPK
NPLVRWGHQFYFNNIVPIIGSLVGGNNRAYTYLPQSASIFPQPPELAQIIAECGWRDVTWKQLGFGAVAVHIATK

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) [H]

COG id: COG2226

COG function: function code H; Methylase involved in ubiquinone/menaquinone biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Homo sapiens, GI116063536, Length=266, Percent_Identity=30.4511278195489, Blast_Score=135, Evalue=2e-32,
Organism=Escherichia coli, GI48994983, Length=232, Percent_Identity=31.8965517241379, Blast_Score=132, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17557039, Length=232, Percent_Identity=30.1724137931034, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6323526, Length=249, Percent_Identity=28.5140562248996, Blast_Score=112, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24641702, Length=247, Percent_Identity=30.7692307692308, Blast_Score=122, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.-

Molecular weight: Translated: 26232; Mature: 26100

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLPQSDQKAVYVNAMFTAIAQRYDLMNRLMTFGLDQGWRRWATKRIKQPQAAWALDVG
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHEEEECC
SGTGDFLPILQQAMPQLSVVGLDFTLAMMQAGQAKREQDTLGHSFINGDGMHLPFEDEAF
CCCCHHHHHHHHHCCHHEEECHHHHHHHHHHCCHHHHHHHHCCHHCCCCCCCCCCCCCCH
DIVTTGFAMRNIVDIRQAFSEMARVTKPGGKLACLEVARPKNPLVRWGHQFYFNNIVPII
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
GSLVGGNNRAYTYLPQSASIFPQPPELAQIIAECGWRDVTWKQLGFGAVAVHIATK
HHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHCCCEEEEEEECC
>Mature Secondary Structure 
SVLPQSDQKAVYVNAMFTAIAQRYDLMNRLMTFGLDQGWRRWATKRIKQPQAAWALDVG
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHEEEECC
SGTGDFLPILQQAMPQLSVVGLDFTLAMMQAGQAKREQDTLGHSFINGDGMHLPFEDEAF
CCCCHHHHHHHHHCCHHEEECHHHHHHHHHHCCHHHHHHHHCCHHCCCCCCCCCCCCCCH
DIVTTGFAMRNIVDIRQAFSEMARVTKPGGKLACLEVARPKNPLVRWGHQFYFNNIVPII
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
GSLVGGNNRAYTYLPQSASIFPQPPELAQIIAECGWRDVTWKQLGFGAVAVHIATK
HHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA