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The map label for this gene is rsbRA [H]

Identifier: 159900838

GI number: 159900838

Start: 5523242

End: 5524321

Strand: Reverse

Name: rsbRA [H]

Synonym: Haur_4325

Alternate gene names: 159900838

Gene position: 5524321-5523242 (Counterclockwise)

Preceding gene: 159900839

Following gene: 159900834

Centisome position: 87.04

GC content: 46.57

Gene sequence:

>1080_bases
ATGGCCGAGCTTGATAATGATCGTCTGCAACAACAACGCTTCGCTCGCATTGTTCGGGGTTCATTGATTTTCCTGTTGGC
ATTTATTTGCTATGACATTGGGTTACAGATCCTTGCGCCAAAGCCTGCGCGTTATTTACACTTGGTCAATTTAATTGGCT
TATTGGGATTTTTAACCGCGAGCTATCTGGTTAATCAACGTGGTCGCACCCCGCAAGCAATGCTGTTGGTTGCCACAGCC
ATGCTCGGCTCAAGCCTTATGATGGCACTTTCTAATCCATTTGCCTTGCCAGTTATTTTGATGATGCCGATTTTAGCCTT
GATTTTGGCGATGCTCTATCTTGAGCAAAAAATGGCACGAGTGCTCAGTGTCGTTGCTTGGCTGTGTATGTTGCTTGCAA
CAATCTTGGCCTACAACGTTAATCTGTTTAATCAAGCAGTCATGCCAAGCATGGAAATAAGCGATTTTGTCGGCTTGGCA
GTTTTAGCAGGCATTGCCTTTTTGGTATTAAATCTGTTTCAATCACGCCTACGCAACAATTTTCTCAAGGCAACCCAAGC
CCAAAAAGAGCTTTTGCAAGCGCAATCGGTGATGGAGCAACAAATTATTGAACGAACGTCAACGCTCTCGCAATTGCAAC
AAACCAACGCCGAACAAACTCGGTTATTAGCTGAGGTGGAACACCAACGGCTGATTATTCGCAATTTATCGGTGCCAATT
TTGCCAATCGATCAACGCACACTGGTGCTGCCTTTGGTCGGCTCGCTCGATCAGCAACGGCTTGATGATGTACGCAACCA
AGCCCTCCAAACAATTAGTCAATTCAAGGCGCGGTATTTGGTGCTTGATATTACGGGCGTGCCGCTGATCGACGATCAGA
TTGCGCTGAGCTTGGTTCGCATTATTGAGGCTTTGAAGTTGTTGGGGGCGAAAACAATTTTAGTGGGAGTCCGGCCTGAT
GTTGCTGCCAGTTTAGCCAGCGGCAACTTGCAATTAGGCAGTGTTACAAGTGCCGCGACCCTGCAAGAAGGCTTAGATTA
TGCTCGAACTCAATCCAAAGCGCTGGCTAAAATTGCATAA

Upstream 100 bases:

>100_bases
CGCCTCAGTACTAGTTCAAAATAGCCCTTTATGGATAGAATAATTGTGTTGATCTCGTTATAATGAGCCTATTCAGCTAG
CTAGCTATAGGAATATGCTC

Downstream 100 bases:

>100_bases
CGCCACCTACGCCGCAACCGTGGATCGGCCCCAAGCAAGAGTTTTTGGCTTGGCAAGCAGCGTTCGAGCAAGGCTCTGCG
CCAAGTACGTGGCTGCCAAT

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MAELDNDRLQQQRFARIVRGSLIFLLAFICYDIGLQILAPKPARYLHLVNLIGLLGFLTASYLVNQRGRTPQAMLLVATA
MLGSSLMMALSNPFALPVILMMPILALILAMLYLEQKMARVLSVVAWLCMLLATILAYNVNLFNQAVMPSMEISDFVGLA
VLAGIAFLVLNLFQSRLRNNFLKATQAQKELLQAQSVMEQQIIERTSTLSQLQQTNAEQTRLLAEVEHQRLIIRNLSVPI
LPIDQRTLVLPLVGSLDQQRLDDVRNQALQTISQFKARYLVLDITGVPLIDDQIALSLVRIIEALKLLGAKTILVGVRPD
VAASLASGNLQLGSVTSAATLQEGLDYARTQSKALAKIA

Sequences:

>Translated_359_residues
MAELDNDRLQQQRFARIVRGSLIFLLAFICYDIGLQILAPKPARYLHLVNLIGLLGFLTASYLVNQRGRTPQAMLLVATA
MLGSSLMMALSNPFALPVILMMPILALILAMLYLEQKMARVLSVVAWLCMLLATILAYNVNLFNQAVMPSMEISDFVGLA
VLAGIAFLVLNLFQSRLRNNFLKATQAQKELLQAQSVMEQQIIERTSTLSQLQQTNAEQTRLLAEVEHQRLIIRNLSVPI
LPIDQRTLVLPLVGSLDQQRLDDVRNQALQTISQFKARYLVLDITGVPLIDDQIALSLVRIIEALKLLGAKTILVGVRPD
VAASLASGNLQLGSVTSAATLQEGLDYARTQSKALAKIA
>Mature_358_residues
AELDNDRLQQQRFARIVRGSLIFLLAFICYDIGLQILAPKPARYLHLVNLIGLLGFLTASYLVNQRGRTPQAMLLVATAM
LGSSLMMALSNPFALPVILMMPILALILAMLYLEQKMARVLSVVAWLCMLLATILAYNVNLFNQAVMPSMEISDFVGLAV
LAGIAFLVLNLFQSRLRNNFLKATQAQKELLQAQSVMEQQIIERTSTLSQLQQTNAEQTRLLAEVEHQRLIIRNLSVPIL
PIDQRTLVLPLVGSLDQQRLDDVRNQALQTISQFKARYLVLDITGVPLIDDQIALSLVRIIEALKLLGAKTILVGVRPDV
AASLASGNLQLGSVTSAATLQEGLDYARTQSKALAKIA

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 39582; Mature: 39451

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELDNDRLQQQRFARIVRGSLIFLLAFICYDIGLQILAPKPARYLHLVNLIGLLGFLTA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHH
SYLVNQRGRTPQAMLLVATAMLGSSLMMALSNPFALPVILMMPILALILAMLYLEQKMAR
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLSVVAWLCMLLATILAYNVNLFNQAVMPSMEISDFVGLAVLAGIAFLVLNLFQSRLRNN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLKATQAQKELLQAQSVMEQQIIERTSTLSQLQQTNAEQTRLLAEVEHQRLIIRNLSVPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCE
LPIDQRTLVLPLVGSLDQQRLDDVRNQALQTISQFKARYLVLDITGVPLIDDQIALSLVR
EECCCCEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHH
IIEALKLLGAKTILVGVRPDVAASLASGNLQLGSVTSAATLQEGLDYARTQSKALAKIA
HHHHHHHHCCHHEEEECCCHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AELDNDRLQQQRFARIVRGSLIFLLAFICYDIGLQILAPKPARYLHLVNLIGLLGFLTA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHH
SYLVNQRGRTPQAMLLVATAMLGSSLMMALSNPFALPVILMMPILALILAMLYLEQKMAR
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLSVVAWLCMLLATILAYNVNLFNQAVMPSMEISDFVGLAVLAGIAFLVLNLFQSRLRNN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLKATQAQKELLQAQSVMEQQIIERTSTLSQLQQTNAEQTRLLAEVEHQRLIIRNLSVPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCE
LPIDQRTLVLPLVGSLDQQRLDDVRNQALQTISQFKARYLVLDITGVPLIDDQIALSLVR
EECCCCEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHH
IIEALKLLGAKTILVGVRPDVAASLASGNLQLGSVTSAATLQEGLDYARTQSKALAKIA
HHHHHHHHCCHHEEEECCCHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]