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The map label for this gene is 159900762

Identifier: 159900762

GI number: 159900762

Start: 5421810

End: 5423483

Strand: Reverse

Name: 159900762

Synonym: Haur_4249

Alternate gene names: NA

Gene position: 5423483-5421810 (Counterclockwise)

Preceding gene: 159900763

Following gene: 159900761

Centisome position: 85.46

GC content: 50.78

Gene sequence:

>1674_bases
ATGCCAGAGATTGATTACACACGCTATTATCGTTTCGCTGAGTTGGTGGAAGCGCTAGAAGGCTTTGCCGCCGAATATCC
CGATTTGATTAGTTTGCAATCGATCGGTAAAAGTTATGAAGGCCGTGATTTGTGGTTAGCGACCGTTACTAATGTTGCAA
CTGGTGGGCCACGCGAAAAGCCAGCCTTTTGGGTTGATGCCAATATCCATGCGAGCGAAGTAACTGGCGCAATGGCTGGC
TTACACTTGATCGATACGCTGCTCAAAGGCTATGGCAACGATGCTGAATGCACGCGGTTGCTTGATCGCACGACCTTCTA
CATTTTGCCACGCTTCAATCCTGATGGAGCTGAACGGGCCTTGACCACGCCCTATGTAGTGCGGTCGAGCGTGCGACCTT
ATCCCTATGCTGAACGCATCGATGGCTTGTATCAAGAAGATATCAACGGCGATGGGATTATTTTGCAGATGCGCTTGGTT
GATCCCAACGGCGATTGGCGGGTCTCCGAGCATGATCCACGGGTGATGGTCAAGCGCAAGCCCTATGAAATTGGCGGCAC
CTACTATCGAATTTTGCCCGAAGGCTTGATTCAAAATTACGATGGGGTCAATATCAAACTGAGCCGCGCAGTCGAAGGCT
TGGATATCAACCGCAACTTTCCAGTTGATTGGCGACCTGAAGCCGAGCAATATGGTGCTGGCCCCTACCCAACCTCTGAG
CCAGAAATCCGCGCTGTGGTGCAATTTATCGTCGATCACCCCGAAATTCATAGTGGCCTGACCTACCACACTTATTCGGG
CGTGCTGCTGCGACCATATGGCGACCGCGCCGATGATCAGATGAATTTGCATGATCTCGATGTGTTTAAGGCGTTGGGTA
AACATGGAACCGAGTTAACCGGTTGGCCCAGTGTTTCGGTTTACCACGATTTTCGTTACCACCCCAAAGATGTGATTACC
GGGGTGTTTGATGATTGGGTCTACGATCACTTGGGTATGTTTGCCTGGACAGTCGAATTTTGGGATTTAGTTGGTTCGGC
AGGGATCAAAGATCGCAAATTTATCGAGTGGTTCAAAGAGCACCCCGAAGAAGATGATCTTAAAATTATGCAATGGGTGG
ATGAGCATGGCGAGGGCTTGTGCTTCTACGATTGGACAGCCTTCGAACATCCCCAGCTTGGCCCAGTTGAAATTGGTGGC
TGGCATCCGATGTATGCCTTCCGTAACCCACCGCCAGCCAAATTGCTTGAAACGATTGCGCCTGTGACCCAATTTGCCTT
AGCTCATGCCGCGATTGCCCCATTCACCACAATTAGCAGCTTTGAGCTTGAGGCGTTGGGCGATAACGTTTATCGGCTGC
AAGCAGTGGTGCAAAATGAAGGTTATTTACCAAGTTATGGCTCGCAAAAAGGCCGCGAACGCAAGGCGACCTTGCCACTT
GAAGCCTTGCTCAATCTACCCGAAGGTTCAAGCCTCAAGCTTGGCCAAGCCAAAACCACGATTGGCGATTTGGAAGGGCG
TTCAGGCCGAGTTTCATTCTTTGGCTTTAGCAATGGTTCGACCACTGATCGCACCAAAGTCGAGTGGGTGGTGCATGTGC
CAAATCCTGGGGTGATTGAATTGACGATCCAAGGTGGACGCGGTGGCATTGCCCGCGCTAAGCTCGAAATCTAA

Upstream 100 bases:

>100_bases
ACTCATCCGAGGGTTTTTTGGTTTAATTTGGGCTTGCATCTTGGTAGAACAATAATGCATAATATGCAATATCATGCATA
GAGTTAGCAATGGAGTGGCT

Downstream 100 bases:

>100_bases
ACTAAAAATCAAGTGATTTCCTTGAACCGCTAGCAGCGATAGCTGTTAGCGGTTTTTGTGTGGCTAGATAAAGCTCCAAC
ATTTAAGCCGAAATTTTTGG

Product: peptidase M14 carboxypeptidase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 556

Protein sequence:

>557_residues
MPEIDYTRYYRFAELVEALEGFAAEYPDLISLQSIGKSYEGRDLWLATVTNVATGGPREKPAFWVDANIHASEVTGAMAG
LHLIDTLLKGYGNDAECTRLLDRTTFYILPRFNPDGAERALTTPYVVRSSVRPYPYAERIDGLYQEDINGDGIILQMRLV
DPNGDWRVSEHDPRVMVKRKPYEIGGTYYRILPEGLIQNYDGVNIKLSRAVEGLDINRNFPVDWRPEAEQYGAGPYPTSE
PEIRAVVQFIVDHPEIHSGLTYHTYSGVLLRPYGDRADDQMNLHDLDVFKALGKHGTELTGWPSVSVYHDFRYHPKDVIT
GVFDDWVYDHLGMFAWTVEFWDLVGSAGIKDRKFIEWFKEHPEEDDLKIMQWVDEHGEGLCFYDWTAFEHPQLGPVEIGG
WHPMYAFRNPPPAKLLETIAPVTQFALAHAAIAPFTTISSFELEALGDNVYRLQAVVQNEGYLPSYGSQKGRERKATLPL
EALLNLPEGSSLKLGQAKTTIGDLEGRSGRVSFFGFSNGSTTDRTKVEWVVHVPNPGVIELTIQGGRGGIARAKLEI

Sequences:

>Translated_557_residues
MPEIDYTRYYRFAELVEALEGFAAEYPDLISLQSIGKSYEGRDLWLATVTNVATGGPREKPAFWVDANIHASEVTGAMAG
LHLIDTLLKGYGNDAECTRLLDRTTFYILPRFNPDGAERALTTPYVVRSSVRPYPYAERIDGLYQEDINGDGIILQMRLV
DPNGDWRVSEHDPRVMVKRKPYEIGGTYYRILPEGLIQNYDGVNIKLSRAVEGLDINRNFPVDWRPEAEQYGAGPYPTSE
PEIRAVVQFIVDHPEIHSGLTYHTYSGVLLRPYGDRADDQMNLHDLDVFKALGKHGTELTGWPSVSVYHDFRYHPKDVIT
GVFDDWVYDHLGMFAWTVEFWDLVGSAGIKDRKFIEWFKEHPEEDDLKIMQWVDEHGEGLCFYDWTAFEHPQLGPVEIGG
WHPMYAFRNPPPAKLLETIAPVTQFALAHAAIAPFTTISSFELEALGDNVYRLQAVVQNEGYLPSYGSQKGRERKATLPL
EALLNLPEGSSLKLGQAKTTIGDLEGRSGRVSFFGFSNGSTTDRTKVEWVVHVPNPGVIELTIQGGRGGIARAKLEI
>Mature_556_residues
PEIDYTRYYRFAELVEALEGFAAEYPDLISLQSIGKSYEGRDLWLATVTNVATGGPREKPAFWVDANIHASEVTGAMAGL
HLIDTLLKGYGNDAECTRLLDRTTFYILPRFNPDGAERALTTPYVVRSSVRPYPYAERIDGLYQEDINGDGIILQMRLVD
PNGDWRVSEHDPRVMVKRKPYEIGGTYYRILPEGLIQNYDGVNIKLSRAVEGLDINRNFPVDWRPEAEQYGAGPYPTSEP
EIRAVVQFIVDHPEIHSGLTYHTYSGVLLRPYGDRADDQMNLHDLDVFKALGKHGTELTGWPSVSVYHDFRYHPKDVITG
VFDDWVYDHLGMFAWTVEFWDLVGSAGIKDRKFIEWFKEHPEEDDLKIMQWVDEHGEGLCFYDWTAFEHPQLGPVEIGGW
HPMYAFRNPPPAKLLETIAPVTQFALAHAAIAPFTTISSFELEALGDNVYRLQAVVQNEGYLPSYGSQKGRERKATLPLE
ALLNLPEGSSLKLGQAKTTIGDLEGRSGRVSFFGFSNGSTTDRTKVEWVVHVPNPGVIELTIQGGRGGIARAKLEI

Specific function: Combines the specificities of mammalian Cpase A and B [H]

COG id: COG2866

COG function: function code E; Predicted carboxypeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M14 family [H]

Homologues:

Organism=Homo sapiens, GI22202611, Length=112, Percent_Identity=34.8214285714286, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI217416390, Length=113, Percent_Identity=34.5132743362832, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI53832021, Length=111, Percent_Identity=37.8378378378378, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI38327526, Length=111, Percent_Identity=37.8378378378378, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI6631081, Length=111, Percent_Identity=37.8378378378378, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI4502997, Length=113, Percent_Identity=33.6283185840708, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI188536053, Length=144, Percent_Identity=34.7222222222222, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI188536051, Length=144, Percent_Identity=34.7222222222222, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25143424, Length=294, Percent_Identity=29.9319727891156, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71990283, Length=117, Percent_Identity=37.6068376068376, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32563699, Length=117, Percent_Identity=37.6068376068376, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193203290, Length=294, Percent_Identity=23.469387755102, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32563693, Length=116, Percent_Identity=33.6206896551724, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193207630, Length=126, Percent_Identity=36.5079365079365, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71997496, Length=112, Percent_Identity=31.25, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25141274, Length=114, Percent_Identity=29.8245614035088, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71990310, Length=125, Percent_Identity=32.8, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71990304, Length=125, Percent_Identity=32.8, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25146607, Length=128, Percent_Identity=30.46875, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI221372165, Length=108, Percent_Identity=40.7407407407407, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI221372158, Length=108, Percent_Identity=40.7407407407407, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI221372169, Length=108, Percent_Identity=40.7407407407407, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221372162, Length=108, Percent_Identity=40.7407407407407, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28574958, Length=134, Percent_Identity=34.3283582089552, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI45553831, Length=113, Percent_Identity=35.3982300884956, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI221329604, Length=113, Percent_Identity=35.3982300884956, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28571082, Length=113, Percent_Identity=35.3982300884956, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24638882, Length=113, Percent_Identity=35.3982300884956, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI221329602, Length=113, Percent_Identity=35.3982300884956, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI45553864, Length=113, Percent_Identity=35.3982300884956, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI221330951, Length=140, Percent_Identity=32.8571428571429, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356641, Length=111, Percent_Identity=36.9369369369369, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000834 [H]

Pfam domain/function: PF00246 Peptidase_M14 [H]

EC number: NA

Molecular weight: Translated: 62732; Mature: 62601

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEIDYTRYYRFAELVEALEGFAAEYPDLISLQSIGKSYEGRDLWLATVTNVATGGPREK
CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEEEEHHHCCCCCCCC
PAFWVDANIHASEVTGAMAGLHLIDTLLKGYGNDAECTRLLDRTTFYILPRFNPDGAERA
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEEEEECCCCHHHC
LTTPYVVRSSVRPYPYAERIDGLYQEDINGDGIILQMRLVDPNGDWRVSEHDPRVMVKRK
CCCCHHHHCCCCCCCCHHHHCCHHHHCCCCCEEEEEEEEECCCCCEEECCCCCEEEEEEC
PYEIGGTYYRILPEGLIQNYDGVNIKLSRAVEGLDINRNFPVDWRPEAEQYGAGPYPTSE
CEECCCEEEEECCHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCC
PEIRAVVQFIVDHPEIHSGLTYHTYSGVLLRPYGDRADDQMNLHDLDVFKALGKHGTELT
HHHHHHHHHHHCCCHHHCCCEEEEECCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCC
GWPSVSVYHDFRYHPKDVITGVFDDWVYDHLGMFAWTVEFWDLVGSAGIKDRKFIEWFKE
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
HPEEDDLKIMQWVDEHGEGLCFYDWTAFEHPQLGPVEIGGWHPMYAFRNPPPAKLLETIA
CCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCCCEEEECCCCHHHHHHHHH
PVTQFALAHAAIAPFTTISSFELEALGDNVYRLQAVVQNEGYLPSYGSQKGRERKATLPL
HHHHHHHHHHHHCCCCCCCCEEEEHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCH
EALLNLPEGSSLKLGQAKTTIGDLEGRSGRVSFFGFSNGSTTDRTKVEWVVHVPNPGVIE
HHHHCCCCCCCEECCCCCCCHHCCCCCCCEEEEEECCCCCCCCCEEEEEEEECCCCCEEE
LTIQGGRGGIARAKLEI
EEEECCCCCEEEEEECC
>Mature Secondary Structure 
PEIDYTRYYRFAELVEALEGFAAEYPDLISLQSIGKSYEGRDLWLATVTNVATGGPREK
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEEEEHHHCCCCCCCC
PAFWVDANIHASEVTGAMAGLHLIDTLLKGYGNDAECTRLLDRTTFYILPRFNPDGAERA
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEEEEECCCCHHHC
LTTPYVVRSSVRPYPYAERIDGLYQEDINGDGIILQMRLVDPNGDWRVSEHDPRVMVKRK
CCCCHHHHCCCCCCCCHHHHCCHHHHCCCCCEEEEEEEEECCCCCEEECCCCCEEEEEEC
PYEIGGTYYRILPEGLIQNYDGVNIKLSRAVEGLDINRNFPVDWRPEAEQYGAGPYPTSE
CEECCCEEEEECCHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCC
PEIRAVVQFIVDHPEIHSGLTYHTYSGVLLRPYGDRADDQMNLHDLDVFKALGKHGTELT
HHHHHHHHHHHCCCHHHCCCEEEEECCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCC
GWPSVSVYHDFRYHPKDVITGVFDDWVYDHLGMFAWTVEFWDLVGSAGIKDRKFIEWFKE
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
HPEEDDLKIMQWVDEHGEGLCFYDWTAFEHPQLGPVEIGGWHPMYAFRNPPPAKLLETIA
CCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCCCEEEECCCCHHHHHHHHH
PVTQFALAHAAIAPFTTISSFELEALGDNVYRLQAVVQNEGYLPSYGSQKGRERKATLPL
HHHHHHHHHHHHCCCCCCCCEEEEHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCH
EALLNLPEGSSLKLGQAKTTIGDLEGRSGRVSFFGFSNGSTTDRTKVEWVVHVPNPGVIE
HHHHCCCCCCCEECCCCCCCHHCCCCCCCEEEEEECCCCCCCCCEEEEEEEECCCCCEEE
LTIQGGRGGIARAKLEI
EEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA