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The map label for this gene is obg

Identifier: 159900740

GI number: 159900740

Start: 5387834

End: 5389147

Strand: Direct

Name: obg

Synonym: Haur_4227

Alternate gene names: 159900740

Gene position: 5387834-5389147 (Clockwise)

Preceding gene: 159900739

Following gene: 159900741

Centisome position: 84.89

GC content: 51.6

Gene sequence:

>1314_bases
ATGTCTGATTTTATAGATCGTGCGCTGATTACAGTCAAAGCTGGTGATGGTGGCGATGGTATGGCCACCTTCCGCCGAGA
AAAATATGTTCCGCGTGGCGGCCCCGATGGTGGCGATGGTGGCCGTGGCGGGAGTGTCTATCTTGAGGTAAGCCCCCATT
TAAATACGCTATTGCCTTTTCGTTTTGAAACTCATTTTGAAGCCGATAAGGGCTTGAACGCTGGTCGGCAGCGCAAACGT
GGCCGTACAGGCGAAGATACGTTTATTCGTGTGCCACCTGGTACGATTGTGAGTGCCGAAATCGAAGGCGAAGTTCAAAC
TGTCGATTTGCTGTTTCCTGGCCAAAAATTGTTGGTAGCGCGGGGCGGCAAGGGCGGCTTGGGCAATACCCACTTTGCCA
CTGCCTCGAATCAAGTGCCACGGATTGCCGAGCTTGGCCAGCCTGGCGAAGAGCGTGAACTACAACTTGAATTAAAAGTC
ATTGCTGATGTTGGCTTGGTCGGCTTCCCCAACGCAGGCAAATCGACCTTGCTCTCGATGGTCAGCGCTGCGCGTCCGAA
AATTGCTAATTATCCATTTACCACACTTTCGCCCAATTTAGGCGTAGCCGAATTCAACGATTTTACCTTTGTGGTAGCCG
ATATTCCAGGTTTGATCGAAGGAGCCAGCCGTGGGGTTGGGCTAGGTCACGATTTCTTGCGCCATATCGAGCGCACTCGC
ATTTTGGTGCATGTGCTCGATGCTGCTGGCACTGAAGGCCGCGATCCCTTTGAAGATTTCTTGACGATCAACGCTGAACT
CAAGGCTTACTCCAGCGAATTGGCGCAACGCCCGCAACTGGTCGCCTTGAACAAAACCGATATTCCCGATGCCGAGGCTT
TTGACGAATTGATGCGTCCGCAAATTATCGCTTGGGGCATTGATCCGGAAAATATCTTTCCAATTTCGGCAGCAACCAAC
CAAGGCCTGCAACCGTTGCAACGCCGGATTGTTGATATTCTACGTGAAATGCCCGAACGGATTACCCGCCTGCCGTACAG
TGAGGAAATTCTGACCTTCCGCTTCAGCAATATCGACCCGAATGATTTCTGGCTCGAAACTGAGGAAGATGGTGTGTTAC
GTGTCCATGGCGAGAAAATTGAACGGCTTGTTTCAATGACGAACTTTGCCCAAAGCGAATCGCTCGAACGACTCCAACGA
GTGTTGGAAGCGATGGGCGTTTCAGCAGCGTTGTTTGCTGCTGGTGTGCGCCATGGCGATCCTGTGCGGATTGAAAAAGC
TGAGTTGTTATGGCAAGACGAGTCGATTGGATGA

Upstream 100 bases:

>100_bases
CGTTTTTGTGTCTAAACGCATTGGACAGCATGCGATTCTTCATGTATCCTGCGTTACAATCACAATTGAATAATTAACCA
CACGAAGCGGGTGACTTTTT

Downstream 100 bases:

>100_bases
TGAGCGATTGGTCTACCAGCCAACCGATTTTTTCGCAGCGCGATGTGCGTCAAACCACATCGCGGCTGGCTCTGACCTTG
CTCGATGGATGTTTGATTTT

Product: GTP-binding protein Obg/CgtA

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MSDFIDRALITVKAGDGGDGMATFRREKYVPRGGPDGGDGGRGGSVYLEVSPHLNTLLPFRFETHFEADKGLNAGRQRKR
GRTGEDTFIRVPPGTIVSAEIEGEVQTVDLLFPGQKLLVARGGKGGLGNTHFATASNQVPRIAELGQPGEERELQLELKV
IADVGLVGFPNAGKSTLLSMVSAARPKIANYPFTTLSPNLGVAEFNDFTFVVADIPGLIEGASRGVGLGHDFLRHIERTR
ILVHVLDAAGTEGRDPFEDFLTINAELKAYSSELAQRPQLVALNKTDIPDAEAFDELMRPQIIAWGIDPENIFPISAATN
QGLQPLQRRIVDILREMPERITRLPYSEEILTFRFSNIDPNDFWLETEEDGVLRVHGEKIERLVSMTNFAQSESLERLQR
VLEAMGVSAALFAAGVRHGDPVRIEKAELLWQDESIG

Sequences:

>Translated_437_residues
MSDFIDRALITVKAGDGGDGMATFRREKYVPRGGPDGGDGGRGGSVYLEVSPHLNTLLPFRFETHFEADKGLNAGRQRKR
GRTGEDTFIRVPPGTIVSAEIEGEVQTVDLLFPGQKLLVARGGKGGLGNTHFATASNQVPRIAELGQPGEERELQLELKV
IADVGLVGFPNAGKSTLLSMVSAARPKIANYPFTTLSPNLGVAEFNDFTFVVADIPGLIEGASRGVGLGHDFLRHIERTR
ILVHVLDAAGTEGRDPFEDFLTINAELKAYSSELAQRPQLVALNKTDIPDAEAFDELMRPQIIAWGIDPENIFPISAATN
QGLQPLQRRIVDILREMPERITRLPYSEEILTFRFSNIDPNDFWLETEEDGVLRVHGEKIERLVSMTNFAQSESLERLQR
VLEAMGVSAALFAAGVRHGDPVRIEKAELLWQDESIG
>Mature_436_residues
SDFIDRALITVKAGDGGDGMATFRREKYVPRGGPDGGDGGRGGSVYLEVSPHLNTLLPFRFETHFEADKGLNAGRQRKRG
RTGEDTFIRVPPGTIVSAEIEGEVQTVDLLFPGQKLLVARGGKGGLGNTHFATASNQVPRIAELGQPGEERELQLELKVI
ADVGLVGFPNAGKSTLLSMVSAARPKIANYPFTTLSPNLGVAEFNDFTFVVADIPGLIEGASRGVGLGHDFLRHIERTRI
LVHVLDAAGTEGRDPFEDFLTINAELKAYSSELAQRPQLVALNKTDIPDAEAFDELMRPQIIAWGIDPENIFPISAATNQ
GLQPLQRRIVDILREMPERITRLPYSEEILTFRFSNIDPNDFWLETEEDGVLRVHGEKIERLVSMTNFAQSESLERLQRV
LEAMGVSAALFAAGVRHGDPVRIEKAELLWQDESIG

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI111955139, Length=317, Percent_Identity=39.7476340694006, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI24308117, Length=324, Percent_Identity=40.1234567901235, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI111955063, Length=273, Percent_Identity=36.996336996337, Blast_Score=152, Evalue=8e-37,
Organism=Homo sapiens, GI4557537, Length=91, Percent_Identity=38.4615384615385, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4758796, Length=126, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI58761500, Length=135, Percent_Identity=32.5925925925926, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1789574, Length=336, Percent_Identity=48.5119047619048, Blast_Score=271, Evalue=4e-74,
Organism=Escherichia coli, GI1787454, Length=138, Percent_Identity=34.0579710144928, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790615, Length=271, Percent_Identity=30.2583025830258, Blast_Score=69, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=347, Percent_Identity=36.8876080691643, Blast_Score=148, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI17552324, Length=306, Percent_Identity=33.0065359477124, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71981008, Length=117, Percent_Identity=35.042735042735, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=32.3741007194245, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17555344, Length=117, Percent_Identity=32.4786324786325, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=194, Percent_Identity=41.7525773195876, Blast_Score=129, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6321612, Length=91, Percent_Identity=37.3626373626374, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319281, Length=127, Percent_Identity=32.2834645669291, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24585318, Length=218, Percent_Identity=42.6605504587156, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI20129375, Length=302, Percent_Identity=40.0662251655629, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24640873, Length=134, Percent_Identity=32.8358208955224, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640877, Length=134, Percent_Identity=32.8358208955224, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640875, Length=134, Percent_Identity=32.8358208955224, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356473, Length=87, Percent_Identity=40.2298850574713, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17981711, Length=171, Percent_Identity=28.0701754385965, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_HERA2 (A9AXD9)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001546987.1
- ProteinModelPortal:   A9AXD9
- SMR:   A9AXD9
- GeneID:   5736081
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_4227
- HOGENOM:   HBG716038
- OMA:   HFTTLVP
- ProtClustDB:   PRK12297
- BioCyc:   HAUR316274:HAUR_4227-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR03595
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF102741 GTP-bd_prot_GTP1/OBG_C; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 47946; Mature: 47815

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFIDRALITVKAGDGGDGMATFRREKYVPRGGPDGGDGGRGGSVYLEVSPHLNTLLPF
CCCHHCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCE
RFETHFEADKGLNAGRQRKRGRTGEDTFIRVPPGTIVSAEIEGEVQTVDLLFPGQKLLVA
EEECCCCCCCCCCCCHHHHCCCCCCCCEEECCCCCEEEEEECCCEEEEEEEECCCEEEEE
RGGKGGLGNTHFATASNQVPRIAELGQPGEERELQLELKVIADVGLVGFPNAGKSTLLSM
ECCCCCCCCCEEECCCCCCCCHHHCCCCCCCCEEEEEEEEEECCCEEECCCCCHHHHHHH
VSAARPKIANYPFTTLSPNLGVAEFNDFTFVVADIPGLIEGASRGVGLGHDFLRHIERTR
HHHCCCCCCCCCCCCCCCCCCCEECCCEEEEEECCCHHHHHCCCCCCCCHHHHHHHHHHH
ILVHVLDAAGTEGRDPFEDFLTINAELKAYSSELAQRPQLVALNKTDIPDAEAFDELMRP
HHHHEEHHCCCCCCCCHHHHEEECHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHCCC
QIIAWGIDPENIFPISAATNQGLQPLQRRIVDILREMPERITRLPYSEEILTFRFSNIDP
EEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
NDFWLETEEDGVLRVHGEKIERLVSMTNFAQSESLERLQRVLEAMGVSAALFAAGVRHGD
CCCEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
PVRIEKAELLWQDESIG
CCEEEHHHHEECCCCCC
>Mature Secondary Structure 
SDFIDRALITVKAGDGGDGMATFRREKYVPRGGPDGGDGGRGGSVYLEVSPHLNTLLPF
CCHHCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCE
RFETHFEADKGLNAGRQRKRGRTGEDTFIRVPPGTIVSAEIEGEVQTVDLLFPGQKLLVA
EEECCCCCCCCCCCCHHHHCCCCCCCCEEECCCCCEEEEEECCCEEEEEEEECCCEEEEE
RGGKGGLGNTHFATASNQVPRIAELGQPGEERELQLELKVIADVGLVGFPNAGKSTLLSM
ECCCCCCCCCEEECCCCCCCCHHHCCCCCCCCEEEEEEEEEECCCEEECCCCCHHHHHHH
VSAARPKIANYPFTTLSPNLGVAEFNDFTFVVADIPGLIEGASRGVGLGHDFLRHIERTR
HHHCCCCCCCCCCCCCCCCCCCEECCCEEEEEECCCHHHHHCCCCCCCCHHHHHHHHHHH
ILVHVLDAAGTEGRDPFEDFLTINAELKAYSSELAQRPQLVALNKTDIPDAEAFDELMRP
HHHHEEHHCCCCCCCCHHHHEEECHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHCCC
QIIAWGIDPENIFPISAATNQGLQPLQRRIVDILREMPERITRLPYSEEILTFRFSNIDP
EEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
NDFWLETEEDGVLRVHGEKIERLVSMTNFAQSESLERLQRVLEAMGVSAALFAAGVRHGD
CCCEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
PVRIEKAELLWQDESIG
CCEEEHHHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA