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The map label for this gene is rsbRD [H]

Identifier: 159900704

GI number: 159900704

Start: 5347173

End: 5348291

Strand: Direct

Name: rsbRD [H]

Synonym: Haur_4191

Alternate gene names: 159900704

Gene position: 5347173-5348291 (Clockwise)

Preceding gene: 159900703

Following gene: 159900705

Centisome position: 84.25

GC content: 44.77

Gene sequence:

>1119_bases
ATGGTTATGCGCTTGCAGGCTTGGCTCCAACGCTTGCCACAACAACATGGGGTTGAACGTCGCCAAGCTATGTTGCTCCA
ACATATAGTACTTATGCTCATCCTCATTTCAGTGATTGGCGTAATTACCGCACCGCTCACTAGTGGCTCTGCGAACCAAC
TACTTTTATCAATCGTGGGCTATAGTGTGCTAGGGTCGAGTTCATTGTTAGTATTATGGCGAATCCGCTTTAATGCCCTG
CAACAAGCAATTTTGATTTTACTTAGCAACTTTCTCATCCAATTATCGATTTCATTTTGGGCAATTGGGGTATATACTCA
AGCGATTGGCTTTATCTTAGTTTCATTCTCGATGCCCATTGTGTTGGCTGGGTTACTACGCAATCGACGAGTTGTGCTAA
CCATGACCAGCCTATCGCTAGCGATTTTTCTGTTGATTGGCTTAGCAGAATCGCGGGGCTTAGCTGGTAAATTATTACTG
CCGATTAATCTCCAATCAATCATTGGTACATTTAGCTTGCTCACAATTCTTCAGGCAGTGATTGTTGATCGCTTTGGCAG
TAATCTACGTCAGACCTTGCATGAAGCCTTAGATCGCGAAGTACGGCTGAATCAATTGCGTGATTCACTGGAAACCACGG
TCAACGAGCGAACAGCCAGTCTAAGCCAAACGCTGGCTGAGCTTGAACAACGCGAGCTTGATTTACAACATACTTTAGCC
ACATTACAACAGAGCAAACAGATTTTTACCCAACTAAGTGCGCCCGTCTTACCTATTTTGCCAAGGATTTTGGTTATTCC
TTTGGTTGGCGAGGTTTCAGGTGAACGGGCTGAGGCGTTTGCCGAGAATATTTTCAATGCGCTTGAAACCAACAAGGCCC
ATACAATTATTCTTGATGTCTCTGGCGTGACAACCATCGATACGTTTATTGGCAAGGCCTTGCTACATATTGCCGGAACT
GTGCGGTTTCTTGAAGTTCGCACTATTTTGGTTGGTTTACGGCCCGAAGTTGCCGAAACCCTGATCGCGCTCCACATTAA
TTTTCCAGCGATTGAAACCTTTGCCAATCTTGAACAAGCAGTTTTATCGCTGATCAATCAACGACGAGAATTGAACTAG

Upstream 100 bases:

>100_bases
ATCCCCTCTACGGGGTACTTAAAACAGGACAAACAACAAGGCAAATAATTGACAAAGGGGGGATAATAAAGCGAATCTAG
ATAGCTAAGGAATCCCCTCT

Downstream 100 bases:

>100_bases
CACCAAAGAGGAACAGGCTATGCTGAGCCGCTGGCGCGTATGGTTTGATCAATTACCACAGACAAGTCTGATTGAACGTC
GTCAAGCACGGGCATTTCAA

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRD [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MVMRLQAWLQRLPQQHGVERRQAMLLQHIVLMLILISVIGVITAPLTSGSANQLLLSIVGYSVLGSSSLLVLWRIRFNAL
QQAILILLSNFLIQLSISFWAIGVYTQAIGFILVSFSMPIVLAGLLRNRRVVLTMTSLSLAIFLLIGLAESRGLAGKLLL
PINLQSIIGTFSLLTILQAVIVDRFGSNLRQTLHEALDREVRLNQLRDSLETTVNERTASLSQTLAELEQRELDLQHTLA
TLQQSKQIFTQLSAPVLPILPRILVIPLVGEVSGERAEAFAENIFNALETNKAHTIILDVSGVTTIDTFIGKALLHIAGT
VRFLEVRTILVGLRPEVAETLIALHINFPAIETFANLEQAVLSLINQRRELN

Sequences:

>Translated_372_residues
MVMRLQAWLQRLPQQHGVERRQAMLLQHIVLMLILISVIGVITAPLTSGSANQLLLSIVGYSVLGSSSLLVLWRIRFNAL
QQAILILLSNFLIQLSISFWAIGVYTQAIGFILVSFSMPIVLAGLLRNRRVVLTMTSLSLAIFLLIGLAESRGLAGKLLL
PINLQSIIGTFSLLTILQAVIVDRFGSNLRQTLHEALDREVRLNQLRDSLETTVNERTASLSQTLAELEQRELDLQHTLA
TLQQSKQIFTQLSAPVLPILPRILVIPLVGEVSGERAEAFAENIFNALETNKAHTIILDVSGVTTIDTFIGKALLHIAGT
VRFLEVRTILVGLRPEVAETLIALHINFPAIETFANLEQAVLSLINQRRELN
>Mature_372_residues
MVMRLQAWLQRLPQQHGVERRQAMLLQHIVLMLILISVIGVITAPLTSGSANQLLLSIVGYSVLGSSSLLVLWRIRFNAL
QQAILILLSNFLIQLSISFWAIGVYTQAIGFILVSFSMPIVLAGLLRNRRVVLTMTSLSLAIFLLIGLAESRGLAGKLLL
PINLQSIIGTFSLLTILQAVIVDRFGSNLRQTLHEALDREVRLNQLRDSLETTVNERTASLSQTLAELEQRELDLQHTLA
TLQQSKQIFTQLSAPVLPILPRILVIPLVGEVSGERAEAFAENIFNALETNKAHTIILDVSGVTTIDTFIGKALLHIAGT
VRFLEVRTILVGLRPEVAETLIALHINFPAIETFANLEQAVLSLINQRRELN

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 41141; Mature: 41141

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMRLQAWLQRLPQQHGVERRQAMLLQHIVLMLILISVIGVITAPLTSGSANQLLLSIVG
CCCHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
YSVLGSSSLLVLWRIRFNALQQAILILLSNFLIQLSISFWAIGVYTQAIGFILVSFSMPI
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAGLLRNRRVVLTMTSLSLAIFLLIGLAESRGLAGKLLLPINLQSIIGTFSLLTILQAV
HHHHHHHCCEEEEEHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHH
IVDRFGSNLRQTLHEALDREVRLNQLRDSLETTVNERTASLSQTLAELEQRELDLQHTLA
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLQQSKQIFTQLSAPVLPILPRILVIPLVGEVSGERAEAFAENIFNALETNKAHTIILDV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEC
SGVTTIDTFIGKALLHIAGTVRFLEVRTILVGLRPEVAETLIALHINFPAIETFANLEQA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
VLSLINQRRELN
HHHHHHHHHCCC
>Mature Secondary Structure
MVMRLQAWLQRLPQQHGVERRQAMLLQHIVLMLILISVIGVITAPLTSGSANQLLLSIVG
CCCHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
YSVLGSSSLLVLWRIRFNALQQAILILLSNFLIQLSISFWAIGVYTQAIGFILVSFSMPI
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAGLLRNRRVVLTMTSLSLAIFLLIGLAESRGLAGKLLLPINLQSIIGTFSLLTILQAV
HHHHHHHCCEEEEEHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHH
IVDRFGSNLRQTLHEALDREVRLNQLRDSLETTVNERTASLSQTLAELEQRELDLQHTLA
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLQQSKQIFTQLSAPVLPILPRILVIPLVGEVSGERAEAFAENIFNALETNKAHTIILDV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEC
SGVTTIDTFIGKALLHIAGTVRFLEVRTILVGLRPEVAETLIALHINFPAIETFANLEQA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
VLSLINQRRELN
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 11157946 [H]