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The map label for this gene is atpA

Identifier: 159900583

GI number: 159900583

Start: 5195478

End: 5197031

Strand: Direct

Name: atpA

Synonym: Haur_4070

Alternate gene names: 159900583

Gene position: 5195478-5197031 (Clockwise)

Preceding gene: 159900582

Following gene: 159900584

Centisome position: 81.86

GC content: 53.02

Gene sequence:

>1554_bases
ATGGCTGTAACAGCAGAAGATATTCTTAGTCGTCTTAAAGCCAGCATCCAGCAACCTGTCGGCGGAGACCCAACTGCGGT
CAACGTCGGGACGGTTGCCAGTGTTGGCGACGGCGTGGCGCGGATCTCAGGTCTGCGCGATGTTATGGCTTCGGAGTTGC
TTGAATTCAAGCAAACGAAGTCAGGCGAAACCGTCATGGGCATCGCGCTGAACTTGGAAAAAGATAACGTCGCTGCCGTT
ATTTTGGGCGATTATCTCGAAATTGAAGAAGGCGACTTGGTACGCTCAACTGGCAAGATTATTTCAGTGCCAGTTGGTCA
AGAGTTGCTTGGCCGTGTCGTTGACCCACTGGGCCGCCCACTCGATGGCAAAGGCCCAATCAGCGCCAGCAAAACCCGCG
AAGTCGAACGGATCGCCCCGGGTGTGATCGAGCGTAAATCGGTGAGCCAACCAGTGCAAACTGGGATCTTGGCGATCGAC
GCACTGATTCCAATCGGGCGTGGTCAACGTGAGTTGATCATCGGCGACCGCCAAACTGGTAAGACCGCGATCGCGATCGA
TACGATCATCAACCAACGCGGTCAAGGTATGGTTTGTGTGTATGTCGCAATCGGCCAAAAGCGCTCGAAAGTGGCTCAAA
CCATCACTACGCTTGAGCAAAATGGCGCGATGGATTACACCATCGTGGTCAATGCTTCAGCTTCAGAATCAGCAGCATTG
CAATATATCGCACCGTACTCAGGCTGTGCCATCGCTGAAGAAGTGATGGAAGTCGGCGTAACGGTCGATGGCAACTTGGT
CAAAGATGCCTTGATCATCTATGACGATTTGTCGAAGCACGCTGTGGCTTATCGCCAAGTGTCGTTGTTGCTGCGCCGCC
CTCCAGGCCGCGAAGCCTACCCTGGCGACGTGTTCTACTTGCACTCACGCTTGTTGGAACGCGCTGCCCGTTTGAGCGAA
GTCAATGGCGGTGGTTCGATTACGGCCTTGCCAATCATCGAAACCCAAGCTAACGACGTTTCAGCCTACATTCCGACCAA
CGTGATTTCGATCACCGACGGTCAAATCTTCTTGGAATCGGACTTGTTCTATGCTGGCCAACGCCCAGCTTTGAACGTTG
GTATCTCGGTGAGCCGCGTAGGTTCATCGGCCCAAACCAAAGCCATGAAGACCGTTGCTGGTAAGATGAAGCTCGAATTG
GCGCAGTTCCGCGAATTGGCAGCCTTTGCGATGTTTGCTTCTGATTTGGATGCAGGCACCAAGGCCCAAATCGAACGCGG
TCAACGCCTTTCAGAATTGCTCAAGCAACCACAATACCAACCAATCGCTTTGGAAGACCAAGTGATTATTCTGTGGGTTG
CTGGCAACGGCTTCTTGGATGATGTTCCAGTTGCTCGGATCAACGACTTCAAGCGCGATTTCTGGCAGTTTATCCACAGC
AGCTATGCTGAGGTTGGCCGCGCGATCGCTAGCGAAAAAGTCTTGAGTGAAGCAACCATCGCCAGCTTGCGCAAGGCCGT
GACCGAATTCAAGCAAACGGCGAGTTATAAATAG

Upstream 100 bases:

>100_bases
AACGCCTCAACGCAGTCCAACGCAATATGATGGCCGGATAACTGTGAGGAGTGATGAGGCTGCCGCTTCATCCTTCATAC
TTCGATCATAGAGGCAAACA

Downstream 100 bases:

>100_bases
ATAGAGGTTGGGGGCTGGGGGTCAGGGGTCAGTTACCTTGATCCCACCCTCGCCTCAATCTCTTTCTTTACGAGGATTTT
ATGGCTTCAGCACGAGAAAT

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MAVTAEDILSRLKASIQQPVGGDPTAVNVGTVASVGDGVARISGLRDVMASELLEFKQTKSGETVMGIALNLEKDNVAAV
ILGDYLEIEEGDLVRSTGKIISVPVGQELLGRVVDPLGRPLDGKGPISASKTREVERIAPGVIERKSVSQPVQTGILAID
ALIPIGRGQRELIIGDRQTGKTAIAIDTIINQRGQGMVCVYVAIGQKRSKVAQTITTLEQNGAMDYTIVVNASASESAAL
QYIAPYSGCAIAEEVMEVGVTVDGNLVKDALIIYDDLSKHAVAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARLSE
VNGGGSITALPIIETQANDVSAYIPTNVISITDGQIFLESDLFYAGQRPALNVGISVSRVGSSAQTKAMKTVAGKMKLEL
AQFRELAAFAMFASDLDAGTKAQIERGQRLSELLKQPQYQPIALEDQVIILWVAGNGFLDDVPVARINDFKRDFWQFIHS
SYAEVGRAIASEKVLSEATIASLRKAVTEFKQTASYK

Sequences:

>Translated_517_residues
MAVTAEDILSRLKASIQQPVGGDPTAVNVGTVASVGDGVARISGLRDVMASELLEFKQTKSGETVMGIALNLEKDNVAAV
ILGDYLEIEEGDLVRSTGKIISVPVGQELLGRVVDPLGRPLDGKGPISASKTREVERIAPGVIERKSVSQPVQTGILAID
ALIPIGRGQRELIIGDRQTGKTAIAIDTIINQRGQGMVCVYVAIGQKRSKVAQTITTLEQNGAMDYTIVVNASASESAAL
QYIAPYSGCAIAEEVMEVGVTVDGNLVKDALIIYDDLSKHAVAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARLSE
VNGGGSITALPIIETQANDVSAYIPTNVISITDGQIFLESDLFYAGQRPALNVGISVSRVGSSAQTKAMKTVAGKMKLEL
AQFRELAAFAMFASDLDAGTKAQIERGQRLSELLKQPQYQPIALEDQVIILWVAGNGFLDDVPVARINDFKRDFWQFIHS
SYAEVGRAIASEKVLSEATIASLRKAVTEFKQTASYK
>Mature_516_residues
AVTAEDILSRLKASIQQPVGGDPTAVNVGTVASVGDGVARISGLRDVMASELLEFKQTKSGETVMGIALNLEKDNVAAVI
LGDYLEIEEGDLVRSTGKIISVPVGQELLGRVVDPLGRPLDGKGPISASKTREVERIAPGVIERKSVSQPVQTGILAIDA
LIPIGRGQRELIIGDRQTGKTAIAIDTIINQRGQGMVCVYVAIGQKRSKVAQTITTLEQNGAMDYTIVVNASASESAALQ
YIAPYSGCAIAEEVMEVGVTVDGNLVKDALIIYDDLSKHAVAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARLSEV
NGGGSITALPIIETQANDVSAYIPTNVISITDGQIFLESDLFYAGQRPALNVGISVSRVGSSAQTKAMKTVAGKMKLELA
QFRELAAFAMFASDLDAGTKAQIERGQRLSELLKQPQYQPIALEDQVIILWVAGNGFLDDVPVARINDFKRDFWQFIHSS
YAEVGRAIASEKVLSEATIASLRKAVTEFKQTASYK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=506, Percent_Identity=58.695652173913, Blast_Score=579, Evalue=1e-165,
Organism=Homo sapiens, GI4757810, Length=506, Percent_Identity=58.695652173913, Blast_Score=579, Evalue=1e-165,
Organism=Homo sapiens, GI19913428, Length=309, Percent_Identity=29.4498381877023, Blast_Score=106, Evalue=7e-23,
Organism=Homo sapiens, GI19913426, Length=314, Percent_Identity=28.343949044586, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI32189394, Length=359, Percent_Identity=24.7910863509749, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI1790172, Length=502, Percent_Identity=56.3745019920319, Blast_Score=548, Evalue=1e-157,
Organism=Escherichia coli, GI1788251, Length=337, Percent_Identity=27.5964391691395, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1790170, Length=348, Percent_Identity=24.4252873563218, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71988063, Length=515, Percent_Identity=57.6699029126214, Blast_Score=578, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI71988080, Length=515, Percent_Identity=57.6699029126214, Blast_Score=578, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI71988074, Length=515, Percent_Identity=53.7864077669903, Blast_Score=525, Evalue=1e-149,
Organism=Caenorhabditis elegans, GI17570191, Length=304, Percent_Identity=27.9605263157895, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17510931, Length=303, Percent_Identity=26.7326732673267, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI25144756, Length=410, Percent_Identity=23.6585365853659, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6319370, Length=492, Percent_Identity=58.5365853658537, Blast_Score=566, Evalue=1e-162,
Organism=Saccharomyces cerevisiae, GI6319603, Length=318, Percent_Identity=29.559748427673, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6322581, Length=440, Percent_Identity=25.4545454545455, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24658560, Length=492, Percent_Identity=60.3658536585366, Blast_Score=581, Evalue=1e-166,
Organism=Drosophila melanogaster, GI281361666, Length=310, Percent_Identity=28.3870967741935, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24646341, Length=310, Percent_Identity=28.3870967741935, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI17136796, Length=310, Percent_Identity=28.3870967741935, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24638766, Length=389, Percent_Identity=23.9074550128535, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28574560, Length=443, Percent_Identity=24.6049661399549, Blast_Score=76, Evalue=6e-14,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_HERA2 (A9AVV2)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001546830.1
- ProteinModelPortal:   A9AVV2
- SMR:   A9AVV2
- GeneID:   5735928
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_4070
- HOGENOM:   HBG565875
- OMA:   LLEFPNK
- ProtClustDB:   PRK09281
- BioCyc:   HAUR316274:HAUR_4070-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 55514; Mature: 55383

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTAEDILSRLKASIQQPVGGDPTAVNVGTVASVGDGVARISGLRDVMASELLEFKQTK
CCCCHHHHHHHHHHHHHCCCCCCCCEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
SGETVMGIALNLEKDNVAAVILGDYLEIEEGDLVRSTGKIISVPVGQELLGRVVDPLGRP
CCCEEEEEEEEECCCCEEEEEEECEEEECCCCEEECCCCEEEECCCHHHHHHHHHHHCCC
LDGKGPISASKTREVERIAPGVIERKSVSQPVQTGILAIDALIPIGRGQRELIIGDRQTG
CCCCCCCCCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCC
KTAIAIDTIINQRGQGMVCVYVAIGQKRSKVAQTITTLEQNGAMDYTIVVNASASESAAL
CEEEEEEHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCE
QYIAPYSGCAIAEEVMEVGVTVDGNLVKDALIIYDDLSKHAVAYRQVSLLLRRPPGREAY
EEECCCCCHHHHHHHHHCCCCCCCCHHHHHEEEEHHHHHHHHHHHHHHHHHCCCCCCCCC
PGDVFYLHSRLLERAARLSEVNGGGSITALPIIETQANDVSAYIPTNVISITDGQIFLES
CCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEC
DLFYAGQRPALNVGISVSRVGSSAQTKAMKTVAGKMKLELAQFRELAAFAMFASDLDAGT
CEEECCCCCCEEECEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KAQIERGQRLSELLKQPQYQPIALEDQVIILWVAGNGFLDDVPVARINDFKRDFWQFIHS
HHHHHHHHHHHHHHHCCCCCCEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
SYAEVGRAIASEKVLSEATIASLRKAVTEFKQTASYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AVTAEDILSRLKASIQQPVGGDPTAVNVGTVASVGDGVARISGLRDVMASELLEFKQTK
CCCHHHHHHHHHHHHHCCCCCCCCEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
SGETVMGIALNLEKDNVAAVILGDYLEIEEGDLVRSTGKIISVPVGQELLGRVVDPLGRP
CCCEEEEEEEEECCCCEEEEEEECEEEECCCCEEECCCCEEEECCCHHHHHHHHHHHCCC
LDGKGPISASKTREVERIAPGVIERKSVSQPVQTGILAIDALIPIGRGQRELIIGDRQTG
CCCCCCCCCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCC
KTAIAIDTIINQRGQGMVCVYVAIGQKRSKVAQTITTLEQNGAMDYTIVVNASASESAAL
CEEEEEEHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCE
QYIAPYSGCAIAEEVMEVGVTVDGNLVKDALIIYDDLSKHAVAYRQVSLLLRRPPGREAY
EEECCCCCHHHHHHHHHCCCCCCCCHHHHHEEEEHHHHHHHHHHHHHHHHHCCCCCCCCC
PGDVFYLHSRLLERAARLSEVNGGGSITALPIIETQANDVSAYIPTNVISITDGQIFLES
CCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEC
DLFYAGQRPALNVGISVSRVGSSAQTKAMKTVAGKMKLELAQFRELAAFAMFASDLDAGT
CEEECCCCCCEEECEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KAQIERGQRLSELLKQPQYQPIALEDQVIILWVAGNGFLDDVPVARINDFKRDFWQFIHS
HHHHHHHHHHHHHHHCCCCCCEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
SYAEVGRAIASEKVLSEATIASLRKAVTEFKQTASYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA