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The map label for this gene is atpB [H]

Identifier: 159900579

GI number: 159900579

Start: 5193253

End: 5194182

Strand: Direct

Name: atpB [H]

Synonym: Haur_4066

Alternate gene names: 159900579

Gene position: 5193253-5194182 (Clockwise)

Preceding gene: 159900577

Following gene: 159900580

Centisome position: 81.83

GC content: 50.75

Gene sequence:

>930_bases
ATGATTTTGCTTGTTGTGCTCTCGTTGGCAGCTACTGCAAAATTGCGCAGTGGCAACGACGAAGCCTTGAAGCACCCCAA
GGGCTTGCAAAATGCCTTGGAATATGGTGTTGAAGTTCTATACAACACCATGCAAGGGGTTAGCCCGAAATATGTAGCCC
GCTTCTTTGTCGTGGTTGCAACCATCTTCTTCTTGGTCTTGCCTTCAAACTGGTTCGGCTTGGTCCCCGGTGTTGGTTCA
CTTGGGGTTTGTTTTGCTGAATCAGAATTAGAAGTGATGCACGGCCATACTCCGGTAGCTGGTGCTGGCCCAAGCGAAAA
AGTCATCGGTGCTCAAAAAGTTTGGTCAGATTACACCAACAAGTGTGCTGGAACTGCTGATACCTTGGTGCGGGCTGAAG
CTTCAGCCCAAGGCATCGTCTTGCCAGCAACCTTGGAAACGCCTGAGCAAATTGCCCAATACAAGGCAGTCTCAGCCGAA
CTCGACCACGCTGGCAAAATCACGCCTTTGTTCCACCCCTTCTTGCGCCCAGGGAGCGCTGACTTGAATATGACCTTGGC
TTTGGCCTTGATCTCATTCGTCGTCACCGAATTCTGGGGCTTCCGCAAGCAAGGCTTTGGCTACTTGGGCAAGTTCTTTA
TCTTCAACCAAGGACCAATTCAGTTCTTCGTCGGGATTATCGAACTCGTTTCAGAATTCGCTCGCATCATCTCGTTTACC
TTCCGGCTTTTCGGCAACATCTTTGCCGGCGAAGTGGTGCTCTTGGTGATGGCGTTCCTGTTCCCAGCCTTGCTTTCATT
GCCATTCTATGGCTTGGAATTGTTCGTGGGCTTGGTTCAAGCCTTCGTGTTTGCAATGCTGACCATGGCGTTTATCGATA
TGGCTGCTGAATCGCACGGCGATCATGGCCACGAAGAACACGCCCACTAA

Upstream 100 bases:

>100_bases
CCTGCCTGTGGGGAAGCCACTGGTGTCGGTTCGCGCTGAGGAAGTTTTCCACATAGGATCATACAACGTCACAAACTCCT
TGTTGTTAACATGGGTTGTG

Downstream 100 bases:

>100_bases
TCGCTTGATCGCCATTTGATCGCATAAAAACGTTCTTTGATACAGATTAAGTTCTTTTGGAGGATAACGCTCATGACGGA
TACAGGTGCACGTTTGTTGG

Product: ATP synthase F0 subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MILLVVLSLAATAKLRSGNDEALKHPKGLQNALEYGVEVLYNTMQGVSPKYVARFFVVVATIFFLVLPSNWFGLVPGVGS
LGVCFAESELEVMHGHTPVAGAGPSEKVIGAQKVWSDYTNKCAGTADTLVRAEASAQGIVLPATLETPEQIAQYKAVSAE
LDHAGKITPLFHPFLRPGSADLNMTLALALISFVVTEFWGFRKQGFGYLGKFFIFNQGPIQFFVGIIELVSEFARIISFT
FRLFGNIFAGEVVLLVMAFLFPALLSLPFYGLELFVGLVQAFVFAMLTMAFIDMAAESHGDHGHEEHAH

Sequences:

>Translated_309_residues
MILLVVLSLAATAKLRSGNDEALKHPKGLQNALEYGVEVLYNTMQGVSPKYVARFFVVVATIFFLVLPSNWFGLVPGVGS
LGVCFAESELEVMHGHTPVAGAGPSEKVIGAQKVWSDYTNKCAGTADTLVRAEASAQGIVLPATLETPEQIAQYKAVSAE
LDHAGKITPLFHPFLRPGSADLNMTLALALISFVVTEFWGFRKQGFGYLGKFFIFNQGPIQFFVGIIELVSEFARIISFT
FRLFGNIFAGEVVLLVMAFLFPALLSLPFYGLELFVGLVQAFVFAMLTMAFIDMAAESHGDHGHEEHAH
>Mature_309_residues
MILLVVLSLAATAKLRSGNDEALKHPKGLQNALEYGVEVLYNTMQGVSPKYVARFFVVVATIFFLVLPSNWFGLVPGVGS
LGVCFAESELEVMHGHTPVAGAGPSEKVIGAQKVWSDYTNKCAGTADTLVRAEASAQGIVLPATLETPEQIAQYKAVSAE
LDHAGKITPLFHPFLRPGSADLNMTLALALISFVVTEFWGFRKQGFGYLGKFFIFNQGPIQFFVGIIELVSEFARIISFT
FRLFGNIFAGEVVLLVMAFLFPALLSLPFYGLELFVGLVQAFVFAMLTMAFIDMAAESHGDHGHEEHAH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=128, Percent_Identity=33.59375, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 33612; Mature: 33612

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLVVLSLAATAKLRSGNDEALKHPKGLQNALEYGVEVLYNTMQGVSPKYVARFFVVVA
CHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TIFFLVLPSNWFGLVPGVGSLGVCFAESELEVMHGHTPVAGAGPSEKVIGAQKVWSDYTN
HHHHHHHCCCCCCCCCCCCCCCEEEECCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
KCAGTADTLVRAEASAQGIVLPATLETPEQIAQYKAVSAELDHAGKITPLFHPFLRPGSA
HCCCCHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCC
DLNMTLALALISFVVTEFWGFRKQGFGYLGKFFIFNQGPIQFFVGIIELVSEFARIISFT
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHH
FRLFGNIFAGEVVLLVMAFLFPALLSLPFYGLELFVGLVQAFVFAMLTMAFIDMAAESHG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DHGHEEHAH
CCCCCCCCC
>Mature Secondary Structure
MILLVVLSLAATAKLRSGNDEALKHPKGLQNALEYGVEVLYNTMQGVSPKYVARFFVVVA
CHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TIFFLVLPSNWFGLVPGVGSLGVCFAESELEVMHGHTPVAGAGPSEKVIGAQKVWSDYTN
HHHHHHHCCCCCCCCCCCCCCCEEEECCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
KCAGTADTLVRAEASAQGIVLPATLETPEQIAQYKAVSAELDHAGKITPLFHPFLRPGSA
HCCCCHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCC
DLNMTLALALISFVVTEFWGFRKQGFGYLGKFFIFNQGPIQFFVGIIELVSEFARIISFT
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHH
FRLFGNIFAGEVVLLVMAFLFPALLSLPFYGLELFVGLVQAFVFAMLTMAFIDMAAESHG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DHGHEEHAH
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA