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The map label for this gene is rsbRA [H]

Identifier: 159900571

GI number: 159900571

Start: 5181528

End: 5182640

Strand: Direct

Name: rsbRA [H]

Synonym: Haur_4058

Alternate gene names: 159900571

Gene position: 5181528-5182640 (Clockwise)

Preceding gene: 159900569

Following gene: 159900572

Centisome position: 81.64

GC content: 48.34

Gene sequence:

>1113_bases
ATGGCAGAAACCATCGCACCGCCCCGTCAGATTGAAGATATGCTGCAAACCTCGAATGAGCAACGGATTAAGTTGTTTAG
TTTGGTTGAAGGTTTAGCATTGTTGGCCGTTATGCTGATTTTGCTGGTTGCTGGCAACGGCCAACAAGTGCAAATTGGCT
TGAGCATTTGTGCGATTGTGGGCACGATGTTGGCCGTTACCTTTGCCTTGCGGCGTTCGCGCTATGTCGAATGGCTGATT
TACGTTAATCTAGCCTCGATTACCTTGATGCTTTCGTTAACTGGGCCAATTATTGGCGAAGTTGATGGCTCGGTCTGGGT
TTTGTTTCAAGTTCCACCATTAATTGCCACAATTGTGTTAAACACTTCGCGGGCAACCACTGTTATTTGCGTTGCATCAT
CAATTATTCTTTCGATTATTATTGGTGGAGAGTTAGCTGGTTTTATTCCAATTAAATTTTTGGTGCCTAAATCGGCCTTA
TTGATCAACTTCTTTTGCCAATTGCTTGTACTGGGAATTATTGCCACGACCGTGCATTTATTGGTTGGGCGGGCCAAACG
TGCGTTTGCCGTGGTGGCCAAAACTGAGGCCAAGTTGGCCCAGCAATTAGCCAACGAGCGTGAATTGGCGCTGCAACGTG
AGCAACTGAATGCCCAATTAAGCCAAAGCCTGGCTGAAATTAGCCAGCGCGATAGCCAAATTCAAGCCGAACAAGCGGCT
CAGGCGGCTTTGCGCGACCAATTGCGTCAACTGAGTTTGCCTGTGATTCCAGTACTCAAACAAACTGTGGTGATGCCATT
AATCGGTGAGCAATTAGCCAACTCCAGCGAGGGGATTGAAGAAACCTTGCTGAATGGGATTAGCCAGCATCGCGCCAAAA
TTGCCATTTTAGATGTAACCGGGGTTCCTACGATTGATACCGAGCTTGGGCGGCGCTTAATTCAAGCCACGGCGGCGGCG
CGTTTGCTTGGAGTTCAGACGATTATCGCCGGAATTCGGCCTGAGGTTGCCCAAACCTTGGTGAGTTTGGGGATTGATTT
TAGCAGCGTGACCACTGTTGCCAGCTTGCAAGATGGCGTTGCAATGGCGATTAAACGTTTAGGCCTTGGCTAA

Upstream 100 bases:

>100_bases
ATAGTGGAAAAATCCCCCCTAGTCTAGCGGCGTTGTCAATCCACAAATTGATTAAATAATGGTAGGATGCAGCAACAACA
TCTTGCACCCGAGGCAATTT

Downstream 100 bases:

>100_bases
TTCATGCTACAATTTGGCAATTCCCCAACCCAACGACAGGATTTAGGCTGAATAGTACCTTTGGTGGCTGCATGGGCTGG
AACATGCCATATCAGCGATT

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MAETIAPPRQIEDMLQTSNEQRIKLFSLVEGLALLAVMLILLVAGNGQQVQIGLSICAIVGTMLAVTFALRRSRYVEWLI
YVNLASITLMLSLTGPIIGEVDGSVWVLFQVPPLIATIVLNTSRATTVICVASSIILSIIIGGELAGFIPIKFLVPKSAL
LINFFCQLLVLGIIATTVHLLVGRAKRAFAVVAKTEAKLAQQLANERELALQREQLNAQLSQSLAEISQRDSQIQAEQAA
QAALRDQLRQLSLPVIPVLKQTVVMPLIGEQLANSSEGIEETLLNGISQHRAKIAILDVTGVPTIDTELGRRLIQATAAA
RLLGVQTIIAGIRPEVAQTLVSLGIDFSSVTTVASLQDGVAMAIKRLGLG

Sequences:

>Translated_370_residues
MAETIAPPRQIEDMLQTSNEQRIKLFSLVEGLALLAVMLILLVAGNGQQVQIGLSICAIVGTMLAVTFALRRSRYVEWLI
YVNLASITLMLSLTGPIIGEVDGSVWVLFQVPPLIATIVLNTSRATTVICVASSIILSIIIGGELAGFIPIKFLVPKSAL
LINFFCQLLVLGIIATTVHLLVGRAKRAFAVVAKTEAKLAQQLANERELALQREQLNAQLSQSLAEISQRDSQIQAEQAA
QAALRDQLRQLSLPVIPVLKQTVVMPLIGEQLANSSEGIEETLLNGISQHRAKIAILDVTGVPTIDTELGRRLIQATAAA
RLLGVQTIIAGIRPEVAQTLVSLGIDFSSVTTVASLQDGVAMAIKRLGLG
>Mature_369_residues
AETIAPPRQIEDMLQTSNEQRIKLFSLVEGLALLAVMLILLVAGNGQQVQIGLSICAIVGTMLAVTFALRRSRYVEWLIY
VNLASITLMLSLTGPIIGEVDGSVWVLFQVPPLIATIVLNTSRATTVICVASSIILSIIIGGELAGFIPIKFLVPKSALL
INFFCQLLVLGIIATTVHLLVGRAKRAFAVVAKTEAKLAQQLANERELALQREQLNAQLSQSLAEISQRDSQIQAEQAAQ
AALRDQLRQLSLPVIPVLKQTVVMPLIGEQLANSSEGIEETLLNGISQHRAKIAILDVTGVPTIDTELGRRLIQATAAAR
LLGVQTIIAGIRPEVAQTLVSLGIDFSSVTTVASLQDGVAMAIKRLGLG

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 39611; Mature: 39479

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETIAPPRQIEDMLQTSNEQRIKLFSLVEGLALLAVMLILLVAGNGQQVQIGLSICAIV
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHH
GTMLAVTFALRRSRYVEWLIYVNLASITLMLSLTGPIIGEVDGSVWVLFQVPPLIATIVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEECHHHHHHHHC
NTSRATTVICVASSIILSIIIGGELAGFIPIKFLVPKSALLINFFCQLLVLGIIATTVHL
CCCCHHHHHHHHHHHHHHHHHCCCHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
LVGRAKRAFAVVAKTEAKLAQQLANERELALQREQLNAQLSQSLAEISQRDSQIQAEQAA
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAALRDQLRQLSLPVIPVLKQTVVMPLIGEQLANSSEGIEETLLNGISQHRAKIAILDVT
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEEEEEC
GVPTIDTELGRRLIQATAAARLLGVQTIIAGIRPEVAQTLVSLGIDFSSVTTVASLQDGV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
AMAIKRLGLG
HHHHHHHCCC
>Mature Secondary Structure 
AETIAPPRQIEDMLQTSNEQRIKLFSLVEGLALLAVMLILLVAGNGQQVQIGLSICAIV
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHH
GTMLAVTFALRRSRYVEWLIYVNLASITLMLSLTGPIIGEVDGSVWVLFQVPPLIATIVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEECHHHHHHHHC
NTSRATTVICVASSIILSIIIGGELAGFIPIKFLVPKSALLINFFCQLLVLGIIATTVHL
CCCCHHHHHHHHHHHHHHHHHCCCHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
LVGRAKRAFAVVAKTEAKLAQQLANERELALQREQLNAQLSQSLAEISQRDSQIQAEQAA
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAALRDQLRQLSLPVIPVLKQTVVMPLIGEQLANSSEGIEETLLNGISQHRAKIAILDVT
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEEEEEC
GVPTIDTELGRRLIQATAAARLLGVQTIIAGIRPEVAQTLVSLGIDFSSVTTVASLQDGV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
AMAIKRLGLG
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]