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The map label for this gene is yycF [H]

Identifier: 159900549

GI number: 159900549

Start: 5152144

End: 5152890

Strand: Direct

Name: yycF [H]

Synonym: Haur_4036

Alternate gene names: 159900549

Gene position: 5152144-5152890 (Clockwise)

Preceding gene: 159900548

Following gene: 159900553

Centisome position: 81.18

GC content: 50.07

Gene sequence:

>747_bases
ATGCGGCTGCTTAACCGAACCAACGAACGCCATGAAGATAACAATCCCCATCAACGTAAAATTCTGGTTGCCGATGATGA
TCCAGCGATTTTGCGCTTGGTTGAGGTGGCGTTAAGCGGCCAGCGTTATCAACTTGTGACGGTTTCCAATGGCCTCGAAG
CGCTCAAAATGTATCGCGATGGTGAATACCAACTCTTGCTGATTGACGTGATGATGCCGTATATTGATGGCTTTACGGTG
ACTGAGCGGATTCGTGCACGCTCCGATGTGCCAATTATCATTATCACTGCGCGTGATGGCACCGATGATGTGGTACATGG
ATTTGAACTCGGCGCTGACGATTATATTACCAAGCCATTTCGTACTGCCGAGTTGCAAGCGCGGGTTGAAGCAATTATTC
GGCGGGTCGAGGGCTATCAACATCGTAAGGCCTCGCCAATTGTGCGCATCGGCGATTTAGAAATTGACGAGCCACGGCAT
AAAGTGCTGCTTGCGGGCGAGGACGTTAATCTTACGCCGATGGAATTCGAGTTGCTCTATTTCCTAGCAGCCAACTCTGG
CCAAGTTTTTGATCGTGAAGTATTGTTTCGTGAAGTTTGGGGCTACGAATATGTTGGCCAAACCAATTTGGTCGATGTGT
GTGTGCGCCGTTTGCGCGAAAAAATCGAAGAGCAACCATCCAAGCCGCGCCGCATCCTGACTGTGCGTGGGGTTGGCTAT
AAACTGGCCGATGGTGGCTCATTGTAA

Upstream 100 bases:

>100_bases
AGAGAGCTAGCAGAGTGGCTAAGCATAAATAGCCCTAGCCGAAAGCACACTTTCTTGGTAGCATACACAGAGATTGGTTA
ATTGTGCAAGGAGTGCTCGT

Downstream 100 bases:

>100_bases
GCATTGAAAATTGATTGTTAGGGATGGTTTTGCTCTATGAAGGACGCAAAGTTACGAAGGGCTATTGGCTTTGGGCTATC
GGAGATTGATTGGCACCTGC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MRLLNRTNERHEDNNPHQRKILVADDDPAILRLVEVALSGQRYQLVTVSNGLEALKMYRDGEYQLLLIDVMMPYIDGFTV
TERIRARSDVPIIIITARDGTDDVVHGFELGADDYITKPFRTAELQARVEAIIRRVEGYQHRKASPIVRIGDLEIDEPRH
KVLLAGEDVNLTPMEFELLYFLAANSGQVFDREVLFREVWGYEYVGQTNLVDVCVRRLREKIEEQPSKPRRILTVRGVGY
KLADGGSL

Sequences:

>Translated_248_residues
MRLLNRTNERHEDNNPHQRKILVADDDPAILRLVEVALSGQRYQLVTVSNGLEALKMYRDGEYQLLLIDVMMPYIDGFTV
TERIRARSDVPIIIITARDGTDDVVHGFELGADDYITKPFRTAELQARVEAIIRRVEGYQHRKASPIVRIGDLEIDEPRH
KVLLAGEDVNLTPMEFELLYFLAANSGQVFDREVLFREVWGYEYVGQTNLVDVCVRRLREKIEEQPSKPRRILTVRGVGY
KLADGGSL
>Mature_248_residues
MRLLNRTNERHEDNNPHQRKILVADDDPAILRLVEVALSGQRYQLVTVSNGLEALKMYRDGEYQLLLIDVMMPYIDGFTV
TERIRARSDVPIIIITARDGTDDVVHGFELGADDYITKPFRTAELQARVEAIIRRVEGYQHRKASPIVRIGDLEIDEPRH
KVLLAGEDVNLTPMEFELLYFLAANSGQVFDREVLFREVWGYEYVGQTNLVDVCVRRLREKIEEQPSKPRRILTVRGVGY
KLADGGSL

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=36.7713004484305, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=35.0877192982456, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=33.7719298245614, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=33.9055793991416, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=33.9285714285714, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=33.0396475770925, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788394, Length=234, Percent_Identity=35.042735042735, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=32.3008849557522, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=35.5555555555556, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=32.9004329004329, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=30.3964757709251, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=27.0386266094421, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=28.6995515695067, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1787229, Length=235, Percent_Identity=30.6382978723404, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790299, Length=124, Percent_Identity=35.4838709677419, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790437, Length=111, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788550, Length=112, Percent_Identity=30.3571428571429, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28449; Mature: 28449

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLNRTNERHEDNNPHQRKILVADDDPAILRLVEVALSGQRYQLVTVSNGLEALKMYRD
CCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHCC
GEYQLLLIDVMMPYIDGFTVTERIRARSDVPIIIITARDGTDDVVHGFELGADDYITKPF
CCEEEEEHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHEECCCCCHHCCCC
RTAELQARVEAIIRRVEGYQHRKASPIVRIGDLEIDEPRHKVLLAGEDVNLTPMEFELLY
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCEECCCCCEEEEECCCCCCCCHHEEEEE
FLAANSGQVFDREVLFREVWGYEYVGQTNLVDVCVRRLREKIEEQPSKPRRILTVRGVGY
EEECCCCCCHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCE
KLADGGSL
EECCCCCC
>Mature Secondary Structure
MRLLNRTNERHEDNNPHQRKILVADDDPAILRLVEVALSGQRYQLVTVSNGLEALKMYRD
CCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHCC
GEYQLLLIDVMMPYIDGFTVTERIRARSDVPIIIITARDGTDDVVHGFELGADDYITKPF
CCEEEEEHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHEECCCCCHHCCCC
RTAELQARVEAIIRRVEGYQHRKASPIVRIGDLEIDEPRHKVLLAGEDVNLTPMEFELLY
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCEECCCCCEEEEECCCCCCCCHHEEEEE
FLAANSGQVFDREVLFREVWGYEYVGQTNLVDVCVRRLREKIEEQPSKPRRILTVRGVGY
EEECCCCCCHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCE
KLADGGSL
EECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]