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The map label for this gene is 159900535

Identifier: 159900535

GI number: 159900535

Start: 5133032

End: 5134918

Strand: Direct

Name: 159900535

Synonym: Haur_4022

Alternate gene names: NA

Gene position: 5133032-5134918 (Clockwise)

Preceding gene: 159900534

Following gene: 159900536

Centisome position: 80.88

GC content: 47.69

Gene sequence:

>1887_bases
ATGACATCTAATACCAAGCAATTAATCATTTGGGTTGGCAATGCTGGCGAGCAACGAACTCAGGCTGCTCAAGCATGGTT
AGCTGACCAAACTGCGGCACGAACTTGGTTGCTCAGCATGAATCGAGCCAATTTGGGCCATTGGGCCGGCTTGAATAGCT
TTGTTAGCTCGCTATTACCAGCGATTAAGGCCCAAGCCCCCGAATTATTAGTCAAATATGATTATGAGTTGGCCTTGGTT
TTGCCGCAATTGCAACGTGAATTGGCTGTGCGCAACCCAAGCCTCACCGATATTAGCAATCCCCAAGAGCGCACCCGCAA
TTATGCTGCTGATCGCGCCTTTCGGATTGTCCAAGGGCTGATTGATTTGGTCCATGAATTCCGCCAAACTGCGCCAGATC
AGCCATGGGTCATTGTTTGTGATCAGTTTGATCAGGCTGGCTCGTTGGTAACCATGTTTTTCAAAGAACTCTTGCGGCGT
GCCGACCCACGCATGAGCTTAACCATTGGCTTTTTAGTTGAACCCAACCAGCCAGAATTGCTGAACGAGTATCACAGCTG
GCATGCGCATGTTGAGGTCGTGCAAGGCGCTTGGCAAGCTGATCCGCCGATTGTTATCGATCCGGCTGAGGCCAAACGCC
AGCTCGAAGTGCTGGAACGTGAGCATACGTTTGATCCAATTGAGATTGAATTGCATCTGCCTCAATTGATTCAGCTGGCA
ACTGCCGCCAACGAGCCACGCAAACGCTTGGGTTTTATGCACGAAGGCTTGTCGATCTGTTCAACTCGTGGTTTATACGC
CGATGCCTTGTATTATGGCGAGCCACTGCGAGTCGCCATGGAACACGAGTTTCCCAAGAGCGTCGATTTTCGCTTGAGTG
CCTACTTAAAGCTCTACAATTGTTATATTGGGCTAAAACAAGCTGAACCAGCCTTGGATATTGCCGAAACTGCGGTGAGC
ATTACTGATAATCCTGCCCGTTTATATAGCTGGTATTATCTGATTGCAATGATTCATGCACGATTTGCCGAGCCACGCGA
TTTTGATAAAGCCGAGTATTACCTCGATTTAGGCATTGAAGCGATAAATAAAGCCGATATTCCAGCGCATGAAAAACTAT
TTCAATCGTCATTCAATCGCAATGGTTTAGCATTAATTCGTCACTTCCAAAAACGCCCCTTGGAAGCGATTGAAATTTGC
CAAGAATGTTACAAAAATCTTGAAACTGGCTTAGATACCGAAGATCATAAGCTGCATCGCTCGGTATTGCTCTACAATAT
TGCTCAGGTTTACGATTCGCTCAAAGATTATCCAAAAGCAATCGAATATTATAGCTTGACGATTGAAATGGACCCCAACT
ACGCTGAATATTATAATGAGCGAGCCAATATTTATCTGCATATCGGCGATTATGCTGCTGCCGAACGCGATTACCAACGC
TCAATCGAGCTTAGCCCACCCTACACCGAAGTTTGGACAAACCTTGGCCAGTGCTACCAAGTTCAAGAACATTTTGAAAA
AGCCATTGGCGCATTCAGCCGAGCGCTCGATATTGACCCCAAAAATGTGGTTGCGCTCAATCATCGAGCTGAATGCTACG
AGGGTTTGGGCCAAACTCAGGCGGCAATTGCCGACTACAGTGCCAGCCTAAAGCTGAAAACCAGCGAAGCCTCAACCTTT
GCCAACCGCGCGATTCTCTACTACGAGTTGGGCGAAATTGAAGCTTCATTGGCCGATTTGAATACCGCCATCAGCCTCCA
ACCCGATCTCGCTGAGCTGTATGAAAATCGTGCGGTCGCTTTGGAAGCGCTCGAACGCCATGCTGAAGCTGAACACGATC
GTCAACAAGCGATTTTGTTGGCCAAAGCCCACGAGGTTAATGGCTAA

Upstream 100 bases:

>100_bases
GTGCTCGATTCAATTTTGGCAGCCATTTTGATCTTTATTAGCCAAGCTGTTGGAATTTTCCTCTGGCTTTGGAGCTTGAT
CCGCAGAAAGGTTAGCGTCG

Downstream 100 bases:

>100_bases
ACTCTAATTTGTTGGCGAAATCATTGCTATACTGAGCCTCAAGGTGTTGCTGCCTTGAGGCTGCTTGTATTTGGGGGTGT
CGATGCCAACCATATTTAGT

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 628; Mature: 627

Protein sequence:

>628_residues
MTSNTKQLIIWVGNAGEQRTQAAQAWLADQTAARTWLLSMNRANLGHWAGLNSFVSSLLPAIKAQAPELLVKYDYELALV
LPQLQRELAVRNPSLTDISNPQERTRNYAADRAFRIVQGLIDLVHEFRQTAPDQPWVIVCDQFDQAGSLVTMFFKELLRR
ADPRMSLTIGFLVEPNQPELLNEYHSWHAHVEVVQGAWQADPPIVIDPAEAKRQLEVLEREHTFDPIEIELHLPQLIQLA
TAANEPRKRLGFMHEGLSICSTRGLYADALYYGEPLRVAMEHEFPKSVDFRLSAYLKLYNCYIGLKQAEPALDIAETAVS
ITDNPARLYSWYYLIAMIHARFAEPRDFDKAEYYLDLGIEAINKADIPAHEKLFQSSFNRNGLALIRHFQKRPLEAIEIC
QECYKNLETGLDTEDHKLHRSVLLYNIAQVYDSLKDYPKAIEYYSLTIEMDPNYAEYYNERANIYLHIGDYAAAERDYQR
SIELSPPYTEVWTNLGQCYQVQEHFEKAIGAFSRALDIDPKNVVALNHRAECYEGLGQTQAAIADYSASLKLKTSEASTF
ANRAILYYELGEIEASLADLNTAISLQPDLAELYENRAVALEALERHAEAEHDRQQAILLAKAHEVNG

Sequences:

>Translated_628_residues
MTSNTKQLIIWVGNAGEQRTQAAQAWLADQTAARTWLLSMNRANLGHWAGLNSFVSSLLPAIKAQAPELLVKYDYELALV
LPQLQRELAVRNPSLTDISNPQERTRNYAADRAFRIVQGLIDLVHEFRQTAPDQPWVIVCDQFDQAGSLVTMFFKELLRR
ADPRMSLTIGFLVEPNQPELLNEYHSWHAHVEVVQGAWQADPPIVIDPAEAKRQLEVLEREHTFDPIEIELHLPQLIQLA
TAANEPRKRLGFMHEGLSICSTRGLYADALYYGEPLRVAMEHEFPKSVDFRLSAYLKLYNCYIGLKQAEPALDIAETAVS
ITDNPARLYSWYYLIAMIHARFAEPRDFDKAEYYLDLGIEAINKADIPAHEKLFQSSFNRNGLALIRHFQKRPLEAIEIC
QECYKNLETGLDTEDHKLHRSVLLYNIAQVYDSLKDYPKAIEYYSLTIEMDPNYAEYYNERANIYLHIGDYAAAERDYQR
SIELSPPYTEVWTNLGQCYQVQEHFEKAIGAFSRALDIDPKNVVALNHRAECYEGLGQTQAAIADYSASLKLKTSEASTF
ANRAILYYELGEIEASLADLNTAISLQPDLAELYENRAVALEALERHAEAEHDRQQAILLAKAHEVNG
>Mature_627_residues
TSNTKQLIIWVGNAGEQRTQAAQAWLADQTAARTWLLSMNRANLGHWAGLNSFVSSLLPAIKAQAPELLVKYDYELALVL
PQLQRELAVRNPSLTDISNPQERTRNYAADRAFRIVQGLIDLVHEFRQTAPDQPWVIVCDQFDQAGSLVTMFFKELLRRA
DPRMSLTIGFLVEPNQPELLNEYHSWHAHVEVVQGAWQADPPIVIDPAEAKRQLEVLEREHTFDPIEIELHLPQLIQLAT
AANEPRKRLGFMHEGLSICSTRGLYADALYYGEPLRVAMEHEFPKSVDFRLSAYLKLYNCYIGLKQAEPALDIAETAVSI
TDNPARLYSWYYLIAMIHARFAEPRDFDKAEYYLDLGIEAINKADIPAHEKLFQSSFNRNGLALIRHFQKRPLEAIEICQ
ECYKNLETGLDTEDHKLHRSVLLYNIAQVYDSLKDYPKAIEYYSLTIEMDPNYAEYYNERANIYLHIGDYAAAERDYQRS
IELSPPYTEVWTNLGQCYQVQEHFEKAIGAFSRALDIDPKNVVALNHRAECYEGLGQTQAAIADYSASLKLKTSEASTFA
NRAILYYELGEIEASLADLNTAISLQPDLAELYENRAVALEALERHAEAEHDRQQAILLAKAHEVNG

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI310131789, Length=177, Percent_Identity=27.1186440677966, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI310123097, Length=177, Percent_Identity=27.1186440677966, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI310110582, Length=177, Percent_Identity=27.1186440677966, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI32307150, Length=199, Percent_Identity=27.6381909547739, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI32307148, Length=199, Percent_Identity=27.6381909547739, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115532692, Length=199, Percent_Identity=27.1356783919598, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115532690, Length=199, Percent_Identity=27.1356783919598, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17647755, Length=199, Percent_Identity=27.1356783919598, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24585827, Length=199, Percent_Identity=27.1356783919598, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24585829, Length=199, Percent_Identity=27.1356783919598, Blast_Score=76, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 71551; Mature: 71419

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSNTKQLIIWVGNAGEQRTQAAQAWLADQTAARTWLLSMNRANLGHWAGLNSFVSSLLP
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHCCHHHHHHHHHH
AIKAQAPELLVKYDYELALVLPQLQRELAVRNPSLTDISNPQERTRNYAADRAFRIVQGL
HHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
IDLVHEFRQTAPDQPWVIVCDQFDQAGSLVTMFFKELLRRADPRMSLTIGFLVEPNQPEL
HHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCHH
LNEYHSWHAHVEVVQGAWQADPPIVIDPAEAKRQLEVLEREHTFDPIEIELHLPQLIQLA
HHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHH
TAANEPRKRLGFMHEGLSICSTRGLYADALYYGEPLRVAMEHEFPKSVDFRLSAYLKLYN
HHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHH
CYIGLKQAEPALDIAETAVSITDNPARLYSWYYLIAMIHARFAEPRDFDKAEYYLDLGIE
HHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEEECCHH
AINKADIPAHEKLFQSSFNRNGLALIRHFQKRPLEAIEICQECYKNLETGLDTEDHKLHR
HHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHH
SVLLYNIAQVYDSLKDYPKAIEYYSLTIEMDPNYAEYYNERANIYLHIGDYAAAERDYQR
HHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCHHHHHCCCCEEEEEECCHHHHHHHHHC
SIELSPPYTEVWTNLGQCYQVQEHFEKAIGAFSRALDIDPKNVVALNHRAECYEGLGQTQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHCCCCHH
AAIADYSASLKLKTSEASTFANRAILYYELGEIEASLADLNTAISLQPDLAELYENRAVA
HHHHCCCCEEEEECCHHHHHHCCEEEEEECCHHHHHHHHCCCEEECCCCHHHHHCCHHHH
LEALERHAEAEHDRQQAILLAKAHEVNG
HHHHHHHHHHHHHHHHEEEEEECCCCCC
>Mature Secondary Structure 
TSNTKQLIIWVGNAGEQRTQAAQAWLADQTAARTWLLSMNRANLGHWAGLNSFVSSLLP
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHCCHHHHHHHHHH
AIKAQAPELLVKYDYELALVLPQLQRELAVRNPSLTDISNPQERTRNYAADRAFRIVQGL
HHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
IDLVHEFRQTAPDQPWVIVCDQFDQAGSLVTMFFKELLRRADPRMSLTIGFLVEPNQPEL
HHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCHH
LNEYHSWHAHVEVVQGAWQADPPIVIDPAEAKRQLEVLEREHTFDPIEIELHLPQLIQLA
HHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHH
TAANEPRKRLGFMHEGLSICSTRGLYADALYYGEPLRVAMEHEFPKSVDFRLSAYLKLYN
HHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHH
CYIGLKQAEPALDIAETAVSITDNPARLYSWYYLIAMIHARFAEPRDFDKAEYYLDLGIE
HHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEEECCHH
AINKADIPAHEKLFQSSFNRNGLALIRHFQKRPLEAIEICQECYKNLETGLDTEDHKLHR
HHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHH
SVLLYNIAQVYDSLKDYPKAIEYYSLTIEMDPNYAEYYNERANIYLHIGDYAAAERDYQR
HHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCHHHHHCCCCEEEEEECCHHHHHHHHHC
SIELSPPYTEVWTNLGQCYQVQEHFEKAIGAFSRALDIDPKNVVALNHRAECYEGLGQTQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHCCCCHH
AAIADYSASLKLKTSEASTFANRAILYYELGEIEASLADLNTAISLQPDLAELYENRAVA
HHHHCCCCEEEEECCHHHHHHCCEEEEEECCHHHHHHHHCCCEEECCCCHHHHHCCHHHH
LEALERHAEAEHDRQQAILLAKAHEVNG
HHHHHHHHHHHHHHHHEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1368342; 8905231 [H]