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The map label for this gene is 159900394

Identifier: 159900394

GI number: 159900394

Start: 4870578

End: 4871753

Strand: Direct

Name: 159900394

Synonym: Haur_3879

Alternate gene names: NA

Gene position: 4870578-4871753 (Clockwise)

Preceding gene: 159900393

Following gene: 159900399

Centisome position: 76.74

GC content: 52.13

Gene sequence:

>1176_bases
ATGCGTTTGATTTTATATCTTGGCAAGGGTGGCGTTGGCAAAACCACAACCGCTGCGGCAACCGCCGTGCGAGCATCGCG
CATGGGCTATCGAACCTTGGTGGTCAGCACCGATGTGGCTCACTCCTTGGCCGATGCGCTCGATTGCCAAGTTGGCCCTA
GCCCCACCAAGCTGAGCGACAACCTTTGGGCCCAAGAAATCAATGTGTTGGAGGAAGTACGCCAACACTGGGGCGAGTTG
CAAGGCTTTGTCTCCAATTTGCTCAAGCGCAAGGGCGTAAACGAAGTTGCCGCCGAAGAACTAGCAGTAATTCCAGGCAT
GGAAGAAGTTGTCAGTTTGTTACATATTCGCAAACAAGCGAAAGAAGGCAACTACGATGCAGTCATTGTTGATGCAGCGC
CAACTGGCGAAACCGTGCGCTTGCTGACCATGCCCGAAACCTTTACTTGGTATGCTTCGCGGGTGATGCAATGGGAAACC
AGCACCATGAAAGTGGCCAAGCCCTTGATTCGGGCATTGGTGCCAGCCTCGGATATGTTCGATACCTTGCCACGCTTTGT
TGAGCAGGTTGAAGCGCTGCGGGCAACCTTAGCCGACCCCAAAATCAGTTCCTATCGTTTGGTGGTCAACCCCGAGCGCA
TGGTAATCAAAGAGGCTCAACGCGCCGCAACCTACTTGGCCTTGTATGGCTATCCGGTCGATGGCGTGGTGCTTAATCGG
GTGATGCCTAGCGATGTGCGTGGCCATAGTTTTATCGAACAAATGCAAGAAATTCAGGCTAGCTATCGCGCTCAAGTTCA
TGATATTTTCACGCCACTGCCAATTTGGGAAGCCCCAATGTATGCCCGTGAGATCAAAGGGCTTGATGATTTGGCCGATG
TGGGGGCAGCCTTATTTGGCGAGCGCAATCCACTTGATGTCTTTTATGTGGGTAAAACCATGGACATCACCAAGCAAGGC
GATCAGTATGAGCTACGTTTGCCTTTACCACATGTCGAAGTTAATAAAGTCAATATGACCAAACGCGGCGATCAGCTGTT
TATTGAAATTGGCAACTTCCGCCGCGAGATGATTTTACCGACGATGTTGGCTGATCGGCCAGCGCTACGCGCGGTGTTTC
GCAATGGCGAGTTGGTCGTACAATTTGGTGCTCCCGCCCCACTCGAAGCTGTGTAA

Upstream 100 bases:

>100_bases
AATACAGCTAGGCTGCAACTACCCAGTTGACCATAACGTCCAAAGCAGCAGTGCAGCGAGTGATTCATGTGTTCTCGCAA
TGCAGCGAAAGGAAAATACA

Downstream 100 bases:

>100_bases
TCGCGGAGTAGGCTATTGGCTAAAGGCGCTGGGCTATCGAAGATTGGCTGGAAATACCAACGATCGTCCCGATAGCCTAG
ATCCGCAAGCTTCGTGGATC

Product: arsenite-activated ATPase ArsA

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MRLILYLGKGGVGKTTTAAATAVRASRMGYRTLVVSTDVAHSLADALDCQVGPSPTKLSDNLWAQEINVLEEVRQHWGEL
QGFVSNLLKRKGVNEVAAEELAVIPGMEEVVSLLHIRKQAKEGNYDAVIVDAAPTGETVRLLTMPETFTWYASRVMQWET
STMKVAKPLIRALVPASDMFDTLPRFVEQVEALRATLADPKISSYRLVVNPERMVIKEAQRAATYLALYGYPVDGVVLNR
VMPSDVRGHSFIEQMQEIQASYRAQVHDIFTPLPIWEAPMYAREIKGLDDLADVGAALFGERNPLDVFYVGKTMDITKQG
DQYELRLPLPHVEVNKVNMTKRGDQLFIEIGNFRREMILPTMLADRPALRAVFRNGELVVQFGAPAPLEAV

Sequences:

>Translated_391_residues
MRLILYLGKGGVGKTTTAAATAVRASRMGYRTLVVSTDVAHSLADALDCQVGPSPTKLSDNLWAQEINVLEEVRQHWGEL
QGFVSNLLKRKGVNEVAAEELAVIPGMEEVVSLLHIRKQAKEGNYDAVIVDAAPTGETVRLLTMPETFTWYASRVMQWET
STMKVAKPLIRALVPASDMFDTLPRFVEQVEALRATLADPKISSYRLVVNPERMVIKEAQRAATYLALYGYPVDGVVLNR
VMPSDVRGHSFIEQMQEIQASYRAQVHDIFTPLPIWEAPMYAREIKGLDDLADVGAALFGERNPLDVFYVGKTMDITKQG
DQYELRLPLPHVEVNKVNMTKRGDQLFIEIGNFRREMILPTMLADRPALRAVFRNGELVVQFGAPAPLEAV
>Mature_391_residues
MRLILYLGKGGVGKTTTAAATAVRASRMGYRTLVVSTDVAHSLADALDCQVGPSPTKLSDNLWAQEINVLEEVRQHWGEL
QGFVSNLLKRKGVNEVAAEELAVIPGMEEVVSLLHIRKQAKEGNYDAVIVDAAPTGETVRLLTMPETFTWYASRVMQWET
STMKVAKPLIRALVPASDMFDTLPRFVEQVEALRATLADPKISSYRLVVNPERMVIKEAQRAATYLALYGYPVDGVVLNR
VMPSDVRGHSFIEQMQEIQASYRAQVHDIFTPLPIWEAPMYAREIKGLDDLADVGAALFGERNPLDVFYVGKTMDITKQG
DQYELRLPLPHVEVNKVNMTKRGDQLFIEIGNFRREMILPTMLADRPALRAVFRNGELVVQFGAPAPLEAV

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=306, Percent_Identity=25.8169934640523, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17557003, Length=293, Percent_Identity=22.1843003412969, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320103, Length=315, Percent_Identity=24.7619047619048, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24586297, Length=306, Percent_Identity=25.8169934640523, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348
- InterPro:   IPR008978 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 43566; Mature: 43566

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLILYLGKGGVGKTTTAAATAVRASRMGYRTLVVSTDVAHSLADALDCQVGPSPTKLSD
CEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHCCCCCCCCCCCCC
NLWAQEINVLEEVRQHWGELQGFVSNLLKRKGVNEVAAEELAVIPGMEEVVSLLHIRKQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
KEGNYDAVIVDAAPTGETVRLLTMPETFTWYASRVMQWETSTMKVAKPLIRALVPASDMF
CCCCCCEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHH
DTLPRFVEQVEALRATLADPKISSYRLVVNPERMVIKEAQRAATYLALYGYPVDGVVLNR
HHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHEEEEECCCCCHHHHHC
VMPSDVRGHSFIEQMQEIQASYRAQVHDIFTPLPIWEAPMYAREIKGLDDLADVGAALFG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHC
ERNPLDVFYVGKTMDITKQGDQYELRLPLPHVEVNKVNMTKRGDQLFIEIGNFRREMILP
CCCCCEEEEECCEEEECCCCCCEEEEECCCCCEEEEEECCCCCCEEEEEECCHHHHHHHH
TMLADRPALRAVFRNGELVVQFGAPAPLEAV
HHHHCCHHHHHHHCCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MRLILYLGKGGVGKTTTAAATAVRASRMGYRTLVVSTDVAHSLADALDCQVGPSPTKLSD
CEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHCCCCCCCCCCCCC
NLWAQEINVLEEVRQHWGELQGFVSNLLKRKGVNEVAAEELAVIPGMEEVVSLLHIRKQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
KEGNYDAVIVDAAPTGETVRLLTMPETFTWYASRVMQWETSTMKVAKPLIRALVPASDMF
CCCCCCEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHH
DTLPRFVEQVEALRATLADPKISSYRLVVNPERMVIKEAQRAATYLALYGYPVDGVVLNR
HHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHEEEEECCCCCHHHHHC
VMPSDVRGHSFIEQMQEIQASYRAQVHDIFTPLPIWEAPMYAREIKGLDDLADVGAALFG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHC
ERNPLDVFYVGKTMDITKQGDQYELRLPLPHVEVNKVNMTKRGDQLFIEIGNFRREMILP
CCCCCEEEEECCEEEECCCCCCEEEEECCCCCEEEEEECCCCCCEEEEEECCHHHHHHHH
TMLADRPALRAVFRNGELVVQFGAPAPLEAV
HHHHCCHHHHHHHCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]