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The map label for this gene is 159900385

Identifier: 159900385

GI number: 159900385

Start: 4864201

End: 4865355

Strand: Direct

Name: 159900385

Synonym: Haur_3870

Alternate gene names: NA

Gene position: 4864201-4865355 (Clockwise)

Preceding gene: 159900384

Following gene: 159900386

Centisome position: 76.64

GC content: 55.84

Gene sequence:

>1155_bases
ATGAACCAGGTTTTTATTGCAGGCACAGCTTGCACCGCCGTTCGCGAACATTATGATCGTTCGTTGCTCGATTTGGCCTT
AGAGGCGCTGCATGGCGCGGTTGGTTCACTCGATCCAAGCTTAATTCAAGCGTTGTATGTTGGCAATGCGCTAGGCGATA
CGCTGAGTGAGCAAAGCCAATTGGGCGCGTATATCGCTGGCGCGGCTGGCTTGAACTGCGAAGCGGTACGGGTTGAAGCG
GCTGGTGCTAGCGGCGCATTGGCTTTGCGTCAAGGCTATTTGGCAATTGCCAGCGGCCAGGCTGATGTGGTGGTCGTGCT
AGGCGTTGAAAAGGCCACTGACAAACTCGATGCTGCTTTGCAGGCTGCCTTGGCCTTGGGCTTGGATGGCGAACTTGAAC
GGGCACTTGGGCTGACATTAACTGGGGCTTGGGCACTGTTGATGCAACGTTATTTGCATGAATATCAATTGCCAGCCACC
GCCTTCGCGCCATTTGCGGTTAATGCACATGCCAATGGGGCTGGCAATCGCCATGCGCTGTATCGCTTTGCAATCAACGC
TCAAAAATGGGCCAATGCCGGCCAAATTGCCGAGCCATTGAATATGCTCGATTGCTCGACGGTGGCCGATGGTGCAGCAG
CAGTGGTGTTGGTCAGCCAACGCTATGCCCGCGAAATAGCGCAGCCAATCGCAATTGTGGGCAGCGCAACCAGCAGCACC
AATGTTGCCTTGGCGCAACGCCCCGATCTGTTGTGGCTTGAAGCGGCAGCAGCTAGCGGTAACAACGCGTTGCAACAAGC
TAAACTCAAGCGCGATGCAATTAACATCATCGAATTAAGCGACCCGCACGGGATTGCCGCAGCCTTGAGTTTAGAGGCAC
TTGGGTATGCCGAACGTGGTCATGCCACACAACTGGCCGCCGAAGGTGTGATTGCCAAGGATGGCGCGTTGCCTTTGGCG
ACTGCTGGGGGCTACAAAGCTCGTGGCGATGTTGGCGGCGCAACCGGAGTCTATCAAGTGGTTGAGTTAGTGGCTCAACT
GCGCGGCCAAGCCGGAGCCAACCAAATTGCCAATGCCAAAACAGCCCTAGCCCAGTGCTTGGGTGGCGTTGGCGCAACTG
CCGTGACTCATATTTTGCAAGTAGCGGAGGTCTAG

Upstream 100 bases:

>100_bases
AGCGCCACGCACCAGCGCCTATCTCAAACGTCGGCAATTAATCGATTATGCCACCTATGCCAAGTGGCGCGGCAAAATTG
TTGAGTAAAGGGGTAGGAGC

Downstream 100 bases:

>100_bases
ATGAATTTACCAAAACAATGGCGACTCAAAGGCCAACGCTACCGCCTCGAAGGCCAGCGCCACAGCGATGGTCGGGTACG
TTTTCCGGCTCAGCCAGCCA

Product: acetyl-CoA acetyltransferase-like protein

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MNQVFIAGTACTAVREHYDRSLLDLALEALHGAVGSLDPSLIQALYVGNALGDTLSEQSQLGAYIAGAAGLNCEAVRVEA
AGASGALALRQGYLAIASGQADVVVVLGVEKATDKLDAALQAALALGLDGELERALGLTLTGAWALLMQRYLHEYQLPAT
AFAPFAVNAHANGAGNRHALYRFAINAQKWANAGQIAEPLNMLDCSTVADGAAAVVLVSQRYAREIAQPIAIVGSATSST
NVALAQRPDLLWLEAAAASGNNALQQAKLKRDAINIIELSDPHGIAAALSLEALGYAERGHATQLAAEGVIAKDGALPLA
TAGGYKARGDVGGATGVYQVVELVAQLRGQAGANQIANAKTALAQCLGGVGATAVTHILQVAEV

Sequences:

>Translated_384_residues
MNQVFIAGTACTAVREHYDRSLLDLALEALHGAVGSLDPSLIQALYVGNALGDTLSEQSQLGAYIAGAAGLNCEAVRVEA
AGASGALALRQGYLAIASGQADVVVVLGVEKATDKLDAALQAALALGLDGELERALGLTLTGAWALLMQRYLHEYQLPAT
AFAPFAVNAHANGAGNRHALYRFAINAQKWANAGQIAEPLNMLDCSTVADGAAAVVLVSQRYAREIAQPIAIVGSATSST
NVALAQRPDLLWLEAAAASGNNALQQAKLKRDAINIIELSDPHGIAAALSLEALGYAERGHATQLAAEGVIAKDGALPLA
TAGGYKARGDVGGATGVYQVVELVAQLRGQAGANQIANAKTALAQCLGGVGATAVTHILQVAEV
>Mature_384_residues
MNQVFIAGTACTAVREHYDRSLLDLALEALHGAVGSLDPSLIQALYVGNALGDTLSEQSQLGAYIAGAAGLNCEAVRVEA
AGASGALALRQGYLAIASGQADVVVVLGVEKATDKLDAALQAALALGLDGELERALGLTLTGAWALLMQRYLHEYQLPAT
AFAPFAVNAHANGAGNRHALYRFAINAQKWANAGQIAEPLNMLDCSTVADGAAAVVLVSQRYAREIAQPIAIVGSATSST
NVALAQRPDLLWLEAAAASGNNALQQAKLKRDAINIIELSDPHGIAAALSLEALGYAERGHATQLAAEGVIAKDGALPLA
TAGGYKARGDVGGATGVYQVVELVAQLRGQAGANQIANAKTALAQCLGGVGATAVTHILQVAEV

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=397, Percent_Identity=24.6851385390428, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI302344767, Length=317, Percent_Identity=24.9211356466877, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI302344760, Length=317, Percent_Identity=24.9211356466877, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI302344762, Length=237, Percent_Identity=26.5822784810127, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17537653, Length=359, Percent_Identity=27.2980501392758, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24585051, Length=395, Percent_Identity=25.3164556962025, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI19921506, Length=395, Percent_Identity=24.8101265822785, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 39195; Mature: 39195

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQVFIAGTACTAVREHYDRSLLDLALEALHGAVGSLDPSLIQALYVGNALGDTLSEQSQ
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LGAYIAGAAGLNCEAVRVEAAGASGALALRQGYLAIASGQADVVVVLGVEKATDKLDAAL
CCEEEECCCCCCCEEEEEEECCCCCHHHHHCCEEEEECCCCCEEEEEECCHHHHHHHHHH
QAALALGLDGELERALGLTLTGAWALLMQRYLHEYQLPATAFAPFAVNAHANGAGNRHAL
HHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHCCCEEEECCCCCCCCCCEE
YRFAINAQKWANAGQIAEPLNMLDCSTVADGAAAVVLVSQRYAREIAQPIAIVGSATSST
EEEEECHHHHCCCCCHHCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHEEEECCCCCC
NVALAQRPDLLWLEAAAASGNNALQQAKLKRDAINIIELSDPHGIAAALSLEALGYAERG
CEEEECCCCEEEEEEECCCCCHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHCCCCCC
HATQLAAEGVIAKDGALPLATAGGYKARGDVGGATGVYQVVELVAQLRGQAGANQIANAK
CHHHHHHCCEEECCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHH
TALAQCLGGVGATAVTHILQVAEV
HHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNQVFIAGTACTAVREHYDRSLLDLALEALHGAVGSLDPSLIQALYVGNALGDTLSEQSQ
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LGAYIAGAAGLNCEAVRVEAAGASGALALRQGYLAIASGQADVVVVLGVEKATDKLDAAL
CCEEEECCCCCCCEEEEEEECCCCCHHHHHCCEEEEECCCCCEEEEEECCHHHHHHHHHH
QAALALGLDGELERALGLTLTGAWALLMQRYLHEYQLPATAFAPFAVNAHANGAGNRHAL
HHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHCCCEEEECCCCCCCCCCEE
YRFAINAQKWANAGQIAEPLNMLDCSTVADGAAAVVLVSQRYAREIAQPIAIVGSATSST
EEEEECHHHHCCCCCHHCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHEEEECCCCCC
NVALAQRPDLLWLEAAAASGNNALQQAKLKRDAINIIELSDPHGIAAALSLEALGYAERG
CEEEECCCCEEEEEEECCCCCHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHCCCCCC
HATQLAAEGVIAKDGALPLATAGGYKARGDVGGATGVYQVVELVAQLRGQAGANQIANAK
CHHHHHHCCEEECCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHH
TALAQCLGGVGATAVTHILQVAEV
HHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]