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The map label for this gene is sdhB [H]

Identifier: 159900303

GI number: 159900303

Start: 4754919

End: 4755671

Strand: Direct

Name: sdhB [H]

Synonym: Haur_3786

Alternate gene names: 159900303

Gene position: 4754919-4755671 (Clockwise)

Preceding gene: 159900302

Following gene: 159900304

Centisome position: 74.92

GC content: 49.27

Gene sequence:

>753_bases
ATGAAAGTAACATTTCGTGTGCCACGCTTCGATGCTGCCACCGATTTTACCGCCAAATATCAGGTCTATCATGTTGAGGT
AAATCAATTTACCACGATTCTTGATGCCTTGAATATCATCAAAGACGAGCAAGATAGCAGCTTGACCTTTCGGCGTGGCT
CGCAATCGGGCATCGATGGCTCGTGTGGCATGATGATTAATGGCCGCAATCGCTTGGCCTCGACCACCCGTGTGCTGTCC
TTAAATAGCACTGAAATTGCCGTGGGACCATTACCAGGTTTCCCAGTCATTCGCGATTTAGTGGTTGATTTCGATTCGTT
CTTTGCCAAAGATGCAGTGATGTTGCCCTATTTGGTCACCGACATCGCCAAGCCTGCTGATGGCAAGGAGCGCTTGCAAA
GCCCCAAAGATGCTAACCGCATCGCCTTGGCTGCTAGCTGTAATCAATGTGGTTGCTGTACCTCGGCCTGCCCAGTTCAC
TGGAGCAACGGCGAATATTATGGCCCATCAGCATTAACTCGCGCCTATCGCTTTGTCGAAGATTCACGCGATACCGCGAT
TAAGGCTCGCTTGGATATTGTTGGCTCAGAAACCGGCGTTTGGCGCTGCCATACCGTGTTCAACTGCTCAGAATGCCCTA
AGTCGATTCCCAATGGCGAAAATATTCAAGCCCTCAAGCGCAAAATTATGCTCAACAAAATTGGCCTTGGGCGGATTGAA
GTTAAAGTTGCTCGAACCGAAGCAACTGTCTAA

Upstream 100 bases:

>100_bases
AGGCTTGAAAAAAGGAAGAATCAGGGATGCGAGCACATCGGCAATTCTGAATGGCGTGAACCAATTCATTTAAGCGCTAG
AACCTAGTGGAGTAGTTTCA

Downstream 100 bases:

>100_bases
ATTCCATGACTGGGCAATCATCAATTCAAACATTGCTGCGCCATTGGCTCAAGCTGTTTGCCTTGGCGATTGCCCAGTTG
GTTCAATATTTCGTCAAGCC

Product: succinate dehydrogenase and fumarate reductase iron-sulfur protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MKVTFRVPRFDAATDFTAKYQVYHVEVNQFTTILDALNIIKDEQDSSLTFRRGSQSGIDGSCGMMINGRNRLASTTRVLS
LNSTEIAVGPLPGFPVIRDLVVDFDSFFAKDAVMLPYLVTDIAKPADGKERLQSPKDANRIALAASCNQCGCCTSACPVH
WSNGEYYGPSALTRAYRFVEDSRDTAIKARLDIVGSETGVWRCHTVFNCSECPKSIPNGENIQALKRKIMLNKIGLGRIE
VKVARTEATV

Sequences:

>Translated_250_residues
MKVTFRVPRFDAATDFTAKYQVYHVEVNQFTTILDALNIIKDEQDSSLTFRRGSQSGIDGSCGMMINGRNRLASTTRVLS
LNSTEIAVGPLPGFPVIRDLVVDFDSFFAKDAVMLPYLVTDIAKPADGKERLQSPKDANRIALAASCNQCGCCTSACPVH
WSNGEYYGPSALTRAYRFVEDSRDTAIKARLDIVGSETGVWRCHTVFNCSECPKSIPNGENIQALKRKIMLNKIGLGRIE
VKVARTEATV
>Mature_250_residues
MKVTFRVPRFDAATDFTAKYQVYHVEVNQFTTILDALNIIKDEQDSSLTFRRGSQSGIDGSCGMMINGRNRLASTTRVLS
LNSTEIAVGPLPGFPVIRDLVVDFDSFFAKDAVMLPYLVTDIAKPADGKERLQSPKDANRIALAASCNQCGCCTSACPVH
WSNGEYYGPSALTRAYRFVEDSRDTAIKARLDIVGSETGVWRCHTVFNCSECPKSIPNGENIQALKRKIMLNKIGLGRIE
VKVARTEATV

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=216, Percent_Identity=38.8888888888889, Blast_Score=155, Evalue=4e-38,
Organism=Escherichia coli, GI1786943, Length=236, Percent_Identity=38.135593220339, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1790596, Length=225, Percent_Identity=36, Blast_Score=138, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17533915, Length=227, Percent_Identity=37.0044052863436, Blast_Score=147, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6322987, Length=230, Percent_Identity=39.5652173913043, Blast_Score=170, Evalue=2e-43,
Organism=Drosophila melanogaster, GI17137106, Length=229, Percent_Identity=37.5545851528384, Blast_Score=149, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24643156, Length=243, Percent_Identity=36.6255144032922, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 27538; Mature: 27538

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTFRVPRFDAATDFTAKYQVYHVEVNQFTTILDALNIIKDEQDSSLTFRRGSQSGIDG
CEEEEECCCCCCCCCCEEEEEEEEEEHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCC
SCGMMINGRNRLASTTRVLSLNSTEIAVGPLPGFPVIRDLVVDFDSFFAKDAVMLPYLVT
CCEEEECCCCHHCCEEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
DIAKPADGKERLQSPKDANRIALAASCNQCGCCTSACPVHWSNGEYYGPSALTRAYRFVE
HHCCCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEECCCCEECHHHHHHHHHHHH
DSRDTAIKARLDIVGSETGVWRCHTVFNCSECPKSIPNGENIQALKRKIMLNKIGLGRIE
CCCCCEEEEEEEEEECCCCEEEEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEE
VKVARTEATV
EEEECCCCCC
>Mature Secondary Structure
MKVTFRVPRFDAATDFTAKYQVYHVEVNQFTTILDALNIIKDEQDSSLTFRRGSQSGIDG
CEEEEECCCCCCCCCCEEEEEEEEEEHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCC
SCGMMINGRNRLASTTRVLSLNSTEIAVGPLPGFPVIRDLVVDFDSFFAKDAVMLPYLVT
CCEEEECCCCHHCCEEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
DIAKPADGKERLQSPKDANRIALAASCNQCGCCTSACPVHWSNGEYYGPSALTRAYRFVE
HHCCCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEECCCCEECHHHHHHHHHHHH
DSRDTAIKARLDIVGSETGVWRCHTVFNCSECPKSIPNGENIQALKRKIMLNKIGLGRIE
CCCCCEEEEEEEEEECCCCEEEEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEE
VKVARTEATV
EEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA