Click here to switch to the map view.

The map label for this gene is malZ [H]

Identifier: 159900222

GI number: 159900222

Start: 4658032

End: 4659885

Strand: Reverse

Name: malZ [H]

Synonym: Haur_3705

Alternate gene names: 159900222

Gene position: 4659885-4658032 (Counterclockwise)

Preceding gene: 159900223

Following gene: 159900215

Centisome position: 73.42

GC content: 51.51

Gene sequence:

>1854_bases
ATGCACTACCCAACTTGGACAAGCGCTGTGCACCACGATGGTTCGGCGCTGTACCTTCAACCAAGCCAGCCCTATCACCT
TGGTCAACAAGTAACTGTTCGCTTGCGAACTCCATTAGCTGCGCCAATTACCCAAGCCTTTATTCGCATCTGCCCCGATG
GCGAGCAAACGTTTGTGGCGATGCAACCAGCCGAACGGACTGAAACGATTCAATGGTGGCAAGGCCAAATCACGCTCTCG
ATGCCGCGCACTGGCTATCGCTTTTGGCTGATGACCGAGCAAGGCGGCTGGTGGCTTTCGGCAGCAGGCATGCAACGTTC
AACCCCTACCGATGCGACCGATTTTAAGTTGTTGGCTGATTATCATGCCCCAACCTGGGTGCATTCAGCAGTGTTCTATC
AAATTTTTCCTGATCGGTTTTGTGATGGCGAGCCAAGCAATAATGTGGTTGATGGCGAATATACAGTTTATGGCAAGCCA
ACGATTGCCCGCCAATGGGGCGAGGCTCCTCAGAAAGCCACGGGTGGTATCGAGTTTTTCGGTGGCGATTTACAGGGTAT
TAGCCAAAAGCTTGATTATCTTGCGCAGCTAGGGATTAATGCGCTGTATCTCACGCCGATTTTTACTGCTCCCTCAAACC
ACAAATACGATACCGCCGATTATCTGCAAATCGATCAGCATTTTGGCGGTGAGGCGGCTTTGGCTGAATTGCGCCAAGCA
ACCCAACGCTACCAGATGAAATTGATGTTGGATATTGTGCTCAATCACTGTGGCTACACTCATCATTGGTTTACGGCGGC
TCAAGCCGATACCAACGCGCCTACCGCTGATTATTTTTCGTGGAAGCAACATCCCAACGAGTATGAATCATGGTTAGGTC
ATCGCTCATTGCCCAAACTCAATTACACCAGCCATGGCTTGCGCCAAGCAATTTATGGCAGCGAACAGGCGATTGTGCGC
CATTGGTTGCGTCAACCCTATGCGATCGATGGCTGGCGAATCGATGTAGCCAATATGTTGGCCCGCCAAGGTTCGAGCCA
GTTAGGGCATAAAATTGGCCGCGCACTGCGCCGCGCCGTAAAAGCCGAATCACCTGAAGCCTATTTACTTGGCGAACATT
TCTATGATGGCACGAATCACCTTCAAGGCGATGAACTTGATGCCAGCATGAACTATCGTGGCTTTACCTTCCCGACCTTG
CAATGGCTAGTTGGCTTCGATATGGCCTCGGTGTGGAACCTGGTTTGGGAAGATCGGGCCTTATTGCCGACTGAAGCCTT
GGGCGAGCAATGGCTGGCCTTTTTGGCCGTGATTCCATGGCAAGTCGCTTTGCAACAATTCAATTTGCTCGATTCGCACG
ATACGCCACGTTTGTTGACGATTGTTGGTGGTGATCTGTCATTACATCACGTCGCAGTTACCCTGCAAATGACCTTCCCG
GGCGTGCCCTGCATCTATTATGGCGATGAAGTCGGCATGCAAGGCGGCGGCGATCCCGAGTGTCGCGGCTGTATGCCATG
GGATGCACAAGTTTGGGATCACGATCTGCTAGCTTTTTATCGTTCGCTGATTGGATTACGCCGTAGTTCGAGCGCTTTGA
GTGTTGGCGGATTTCAATTATTGCTGGCCGAAGGCGATACGGTGGCCTTTATGCGGCGCAGCGCTGATGAATGTTTGTTG
ATCGTTGCCCAGCGGGCTGCTACCAGCATTCCCCCAATTCCAATGTTCGCAACCGGATTGACTGATGGTACAAGCTTTAT
CAAAGTCGCTGGCACAACGAAAATTACGATTCAGGCTGGGGTACTAGTTTTGCCACAAACTGGCATTAGCGCCAGCATCT
GGCAAATGCAGTAG

Upstream 100 bases:

>100_bases
GGTGAGGGAACTCAATCCAATGAACCATTATACCTAGAACTAAAAACCGACCCCCGGCCCCCAGCAACCAATCCCCATGT
ATTAATAATGAGAAAGACCA

Downstream 100 bases:

>100_bases
GATTCGGGGATCGGGGGTTGGGGGTTGGGGATCGACTGGATGTGGTATGCCCTCGCCCCTCGCCTGTACGCGAGGCGAGG
GGAACCGCTCAGGGAATACT

Product: alpha amylase catalytic subunit

Products: NA

Alternate protein names: Alpha-glucosidase [H]

Number of amino acids: Translated: 617; Mature: 617

Protein sequence:

>617_residues
MHYPTWTSAVHHDGSALYLQPSQPYHLGQQVTVRLRTPLAAPITQAFIRICPDGEQTFVAMQPAERTETIQWWQGQITLS
MPRTGYRFWLMTEQGGWWLSAAGMQRSTPTDATDFKLLADYHAPTWVHSAVFYQIFPDRFCDGEPSNNVVDGEYTVYGKP
TIARQWGEAPQKATGGIEFFGGDLQGISQKLDYLAQLGINALYLTPIFTAPSNHKYDTADYLQIDQHFGGEAALAELRQA
TQRYQMKLMLDIVLNHCGYTHHWFTAAQADTNAPTADYFSWKQHPNEYESWLGHRSLPKLNYTSHGLRQAIYGSEQAIVR
HWLRQPYAIDGWRIDVANMLARQGSSQLGHKIGRALRRAVKAESPEAYLLGEHFYDGTNHLQGDELDASMNYRGFTFPTL
QWLVGFDMASVWNLVWEDRALLPTEALGEQWLAFLAVIPWQVALQQFNLLDSHDTPRLLTIVGGDLSLHHVAVTLQMTFP
GVPCIYYGDEVGMQGGGDPECRGCMPWDAQVWDHDLLAFYRSLIGLRRSSSALSVGGFQLLLAEGDTVAFMRRSADECLL
IVAQRAATSIPPIPMFATGLTDGTSFIKVAGTTKITIQAGVLVLPQTGISASIWQMQ

Sequences:

>Translated_617_residues
MHYPTWTSAVHHDGSALYLQPSQPYHLGQQVTVRLRTPLAAPITQAFIRICPDGEQTFVAMQPAERTETIQWWQGQITLS
MPRTGYRFWLMTEQGGWWLSAAGMQRSTPTDATDFKLLADYHAPTWVHSAVFYQIFPDRFCDGEPSNNVVDGEYTVYGKP
TIARQWGEAPQKATGGIEFFGGDLQGISQKLDYLAQLGINALYLTPIFTAPSNHKYDTADYLQIDQHFGGEAALAELRQA
TQRYQMKLMLDIVLNHCGYTHHWFTAAQADTNAPTADYFSWKQHPNEYESWLGHRSLPKLNYTSHGLRQAIYGSEQAIVR
HWLRQPYAIDGWRIDVANMLARQGSSQLGHKIGRALRRAVKAESPEAYLLGEHFYDGTNHLQGDELDASMNYRGFTFPTL
QWLVGFDMASVWNLVWEDRALLPTEALGEQWLAFLAVIPWQVALQQFNLLDSHDTPRLLTIVGGDLSLHHVAVTLQMTFP
GVPCIYYGDEVGMQGGGDPECRGCMPWDAQVWDHDLLAFYRSLIGLRRSSSALSVGGFQLLLAEGDTVAFMRRSADECLL
IVAQRAATSIPPIPMFATGLTDGTSFIKVAGTTKITIQAGVLVLPQTGISASIWQMQ
>Mature_617_residues
MHYPTWTSAVHHDGSALYLQPSQPYHLGQQVTVRLRTPLAAPITQAFIRICPDGEQTFVAMQPAERTETIQWWQGQITLS
MPRTGYRFWLMTEQGGWWLSAAGMQRSTPTDATDFKLLADYHAPTWVHSAVFYQIFPDRFCDGEPSNNVVDGEYTVYGKP
TIARQWGEAPQKATGGIEFFGGDLQGISQKLDYLAQLGINALYLTPIFTAPSNHKYDTADYLQIDQHFGGEAALAELRQA
TQRYQMKLMLDIVLNHCGYTHHWFTAAQADTNAPTADYFSWKQHPNEYESWLGHRSLPKLNYTSHGLRQAIYGSEQAIVR
HWLRQPYAIDGWRIDVANMLARQGSSQLGHKIGRALRRAVKAESPEAYLLGEHFYDGTNHLQGDELDASMNYRGFTFPTL
QWLVGFDMASVWNLVWEDRALLPTEALGEQWLAFLAVIPWQVALQQFNLLDSHDTPRLLTIVGGDLSLHHVAVTLQMTFP
GVPCIYYGDEVGMQGGGDPECRGCMPWDAQVWDHDLLAFYRSLIGLRRSSSALSVGGFQLLLAEGDTVAFMRRSADECLL
IVAQRAATSIPPIPMFATGLTDGTSFIKVAGTTKITIQAGVLVLPQTGISASIWQMQ

Specific function: May play a role in regulating the intracellular level of maltotriose. Cleaves glucose from the reducing end of maltotriose and longer maltodextrins with a chain length of up to 7 glucose units [H]

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=376, Percent_Identity=23.6702127659574, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1786604, Length=586, Percent_Identity=38.5665529010239, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1790687, Length=416, Percent_Identity=24.2788461538462, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1789995, Length=155, Percent_Identity=32.258064516129, Blast_Score=79, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI32565753, Length=196, Percent_Identity=26.0204081632653, Blast_Score=69, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322245, Length=436, Percent_Identity=24.7706422018349, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6321726, Length=249, Percent_Identity=27.3092369477912, Blast_Score=101, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322241, Length=249, Percent_Identity=27.3092369477912, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6322021, Length=249, Percent_Identity=27.3092369477912, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6324416, Length=249, Percent_Identity=27.3092369477912, Blast_Score=100, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6321731, Length=250, Percent_Identity=26.8, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6319776, Length=250, Percent_Identity=26.8, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24586593, Length=260, Percent_Identity=27.6923076923077, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24583747, Length=454, Percent_Identity=24.6696035242291, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24583749, Length=454, Percent_Identity=24.6696035242291, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24586589, Length=278, Percent_Identity=26.6187050359712, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24586599, Length=174, Percent_Identity=29.8850574712644, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI45549022, Length=282, Percent_Identity=23.4042553191489, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221330053, Length=174, Percent_Identity=29.8850574712644, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24586591, Length=241, Percent_Identity=24.4813278008299, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24586597, Length=174, Percent_Identity=29.8850574712644, Blast_Score=73, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR004185
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR013783
- InterPro:   IPR014756
- InterPro:   IPR017069 [H]

Pfam domain/function: PF00128 Alpha-amylase; PF02903 Alpha-amylase_N [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 69109; Mature: 69109

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYPTWTSAVHHDGSALYLQPSQPYHLGQQVTVRLRTPLAAPITQAFIRICPDGEQTFVA
CCCCCCCHHHCCCCCEEEECCCCCCCCCCEEEEEEECCCCHHHHHHHHEECCCCCCEEEE
MQPAERTETIQWWQGQITLSMPRTGYRFWLMTEQGGWWLSAAGMQRSTPTDATDFKLLAD
ECCCCCCCCEEEEECEEEEECCCCCEEEEEEEECCCEEEEECCCCCCCCCCCCCEEEEEC
YHAPTWVHSAVFYQIFPDRFCDGEPSNNVVDGEYTVYGKPTIARQWGEAPQKATGGIEFF
CCCCHHHHHHHHHHHCCHHCCCCCCCCCEECCEEEEECCCHHHHHHCCCCCHHCCCEEEE
GGDLQGISQKLDYLAQLGINALYLTPIFTAPSNHKYDTADYLQIDQHFGGEAALAELRQA
CCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCHHHEEEHHHCCCHHHHHHHHHH
TQRYQMKLMLDIVLNHCGYTHHWFTAAQADTNAPTADYFSWKQHPNEYESWLGHRSLPKL
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHCCHHCCCCHHHHHCCCCCCCCC
NYTSHGLRQAIYGSEQAIVRHWLRQPYAIDGWRIDVANMLARQGSSQLGHKIGRALRRAV
CCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHCCCHHHHHHHHHHHHHHH
KAESPEAYLLGEHFYDGTNHLQGDELDASMNYRGFTFPTLQWLVGFDMASVWNLVWEDRA
HCCCCCEEEEECHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCC
LLPTEALGEQWLAFLAVIPWQVALQQFNLLDSHDTPRLLTIVGGDLSLHHVAVTLQMTFP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEEEEEEEECC
GVPCIYYGDEVGMQGGGDPECRGCMPWDAQVWDHDLLAFYRSLIGLRRSSSALSVGGFQL
CCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCEEE
LLAEGDTVAFMRRSADECLLIVAQRAATSIPPIPMFATGLTDGTSFIKVAGTTKITIQAG
EEECCCEEEEHHCCCCCEEEEEEHHHHCCCCCCCEEECCCCCCCCEEEEECCEEEEEEEC
VLVLPQTGISASIWQMQ
EEEEECCCCCCEEEECC
>Mature Secondary Structure
MHYPTWTSAVHHDGSALYLQPSQPYHLGQQVTVRLRTPLAAPITQAFIRICPDGEQTFVA
CCCCCCCHHHCCCCCEEEECCCCCCCCCCEEEEEEECCCCHHHHHHHHEECCCCCCEEEE
MQPAERTETIQWWQGQITLSMPRTGYRFWLMTEQGGWWLSAAGMQRSTPTDATDFKLLAD
ECCCCCCCCEEEEECEEEEECCCCCEEEEEEEECCCEEEEECCCCCCCCCCCCCEEEEEC
YHAPTWVHSAVFYQIFPDRFCDGEPSNNVVDGEYTVYGKPTIARQWGEAPQKATGGIEFF
CCCCHHHHHHHHHHHCCHHCCCCCCCCCEECCEEEEECCCHHHHHHCCCCCHHCCCEEEE
GGDLQGISQKLDYLAQLGINALYLTPIFTAPSNHKYDTADYLQIDQHFGGEAALAELRQA
CCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCHHHEEEHHHCCCHHHHHHHHHH
TQRYQMKLMLDIVLNHCGYTHHWFTAAQADTNAPTADYFSWKQHPNEYESWLGHRSLPKL
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHCCHHCCCCHHHHHCCCCCCCCC
NYTSHGLRQAIYGSEQAIVRHWLRQPYAIDGWRIDVANMLARQGSSQLGHKIGRALRRAV
CCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHCCCHHHHHHHHHHHHHHH
KAESPEAYLLGEHFYDGTNHLQGDELDASMNYRGFTFPTLQWLVGFDMASVWNLVWEDRA
HCCCCCEEEEECHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCC
LLPTEALGEQWLAFLAVIPWQVALQQFNLLDSHDTPRLLTIVGGDLSLHHVAVTLQMTFP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEEEEEEEECC
GVPCIYYGDEVGMQGGGDPECRGCMPWDAQVWDHDLLAFYRSLIGLRRSSSALSVGGFQL
CCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCEEE
LLAEGDTVAFMRRSADECLLIVAQRAATSIPPIPMFATGLTDGTSFIKVAGTTKITIQAG
EEECCCEEEEHHCCCCCEEEEEEHHHHCCCCCCCEEECCCCCCCCEEEEECCEEEEEEEC
VLVLPQTGISASIWQMQ
EEEEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1918057; 9278503; 1706703 [H]