Click here to switch to the map view.

The map label for this gene is lon [H]

Identifier: 159900220

GI number: 159900220

Start: 4656932

End: 4657573

Strand: Direct

Name: lon [H]

Synonym: Haur_3703

Alternate gene names: 159900220

Gene position: 4656932-4657573 (Clockwise)

Preceding gene: 159900219

Following gene: 159900221

Centisome position: 73.38

GC content: 50.47

Gene sequence:

>642_bases
ATGCAACGATTACCTTTGTTTCCGTTAAACGTGGTGTTGTTTCCTGGAGCACAACTGCCGCTGCATATTTTCGAGCCGCG
CTATCGCACAATGATTAGTCGCTGTCTTGAGGAAAGCAAGCCGTTTGGGGTAGTGCTGATTCGCGAGGGCGTTGAGGTTG
GTGGTTCAGCCGTGCCACATATGGTTGGCACAACCGCCGATATTCAAAGCGCCTATCGGTTAGCTGATGGCCGAATGTAT
ATTGTGACCGAAGGCCGCCAACGCTTCCGCATCAACTATCCACTTAGCGTTGACCCGTACATGGTTGCAATGGTCACGAT
GCTTGATGATGATGTCAACGATCGCCATCAAGCTGATGAATTGACCGCGCTTTATTCACAATACCACCGTACCGTTGCCG
CCGCGACTGGCATGCGCTCCAATGCGATCGATCTGCCCAGTGAGCCAGTGAGTTTAAGTTATAAGCTAGCCGACTCGATG
CAGATGGCCTTGCCAATTAAACAACGTTGGCTTGAATCCGATCTTGATCAACGGATTCATGAATTGATCGAGGCGCTACA
ATTTGAGCTAGCGCTCCTGCCCAACATTCCGCCCGACCAGTTGGATCGTGAACCACCTTTTGAAAACACTTCGTGGAATT
AA

Upstream 100 bases:

>100_bases
TGCCCATTTGAGCGAACAACTCGCCTAGCGCATTGTTTTGCGAGCTATGGCCATGGTACAATCACAACCAAGGCCATAGC
TATGGCAAACGAGAGCGCTT

Downstream 100 bases:

>100_bases
GTGCCACGTCACAATTATGTTAATTGCTAGTGTTCGACTTGAACTCTTCATCCCCGCCGTTCATTCACTCAAAGAAAAAC
GTAGTGTGCTTAAATCGATC

Product: peptidase S16 lon domain-containing protein

Products: NA

Alternate protein names: ATP-dependent protease La [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MQRLPLFPLNVVLFPGAQLPLHIFEPRYRTMISRCLEESKPFGVVLIREGVEVGGSAVPHMVGTTADIQSAYRLADGRMY
IVTEGRQRFRINYPLSVDPYMVAMVTMLDDDVNDRHQADELTALYSQYHRTVAAATGMRSNAIDLPSEPVSLSYKLADSM
QMALPIKQRWLESDLDQRIHELIEALQFELALLPNIPPDQLDREPPFENTSWN

Sequences:

>Translated_213_residues
MQRLPLFPLNVVLFPGAQLPLHIFEPRYRTMISRCLEESKPFGVVLIREGVEVGGSAVPHMVGTTADIQSAYRLADGRMY
IVTEGRQRFRINYPLSVDPYMVAMVTMLDDDVNDRHQADELTALYSQYHRTVAAATGMRSNAIDLPSEPVSLSYKLADSM
QMALPIKQRWLESDLDQRIHELIEALQFELALLPNIPPDQLDREPPFENTSWN
>Mature_213_residues
MQRLPLFPLNVVLFPGAQLPLHIFEPRYRTMISRCLEESKPFGVVLIREGVEVGGSAVPHMVGTTADIQSAYRLADGRMY
IVTEGRQRFRINYPLSVDPYMVAMVTMLDDDVNDRHQADELTALYSQYHRTVAAATGMRSNAIDLPSEPVSLSYKLADSM
QMALPIKQRWLESDLDQRIHELIEALQFELALLPNIPPDQLDREPPFENTSWN

Specific function: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced

COG id: COG2802

COG function: function code R; Uncharacterized protein, similar to the N-terminal domain of Lon protease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Lon domain [H]

Homologues:

None

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008269
- InterPro:   IPR004815
- InterPro:   IPR003111
- InterPro:   IPR008268
- InterPro:   IPR001984
- InterPro:   IPR015947
- InterPro:   IPR020568 [H]

Pfam domain/function: PF00004 AAA; PF02190 LON; PF05362 Lon_C [H]

EC number: =3.4.21.53 [H]

Molecular weight: Translated: 24242; Mature: 24242

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRLPLFPLNVVLFPGAQLPLHIFEPRYRTMISRCLEESKPFGVVLIREGVEVGGSAVPH
CCCCCCCCCEEEEECCCCCCEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCH
MVGTTADIQSAYRLADGRMYIVTEGRQRFRINYPLSVDPYMVAMVTMLDDDVNDRHQADE
HHCCHHHHHHHHHHCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHH
LTALYSQYHRTVAAATGMRSNAIDLPSEPVSLSYKLADSMQMALPIKQRWLESDLDQRIH
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
ELIEALQFELALLPNIPPDQLDREPPFENTSWN
HHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MQRLPLFPLNVVLFPGAQLPLHIFEPRYRTMISRCLEESKPFGVVLIREGVEVGGSAVPH
CCCCCCCCCEEEEECCCCCCEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCH
MVGTTADIQSAYRLADGRMYIVTEGRQRFRINYPLSVDPYMVAMVTMLDDDVNDRHQADE
HHCCHHHHHHHHHHCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHH
LTALYSQYHRTVAAATGMRSNAIDLPSEPVSLSYKLADSMQMALPIKQRWLESDLDQRIH
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
ELIEALQFELALLPNIPPDQLDREPPFENTSWN
HHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA