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The map label for this gene is rsmH

Identifier: 159900036

GI number: 159900036

Start: 4430818

End: 4431831

Strand: Reverse

Name: rsmH

Synonym: Haur_3519

Alternate gene names: 159900036

Gene position: 4431831-4430818 (Counterclockwise)

Preceding gene: 159900037

Following gene: 159900035

Centisome position: 69.83

GC content: 54.24

Gene sequence:

>1014_bases
ATGGTGAGTATGCATATTCCAGTTTTATATGATGCCGCACTGGCAGCCTTGAATTTACGCCCAGATGGGCGCTATATCGA
TGGCACGCTTGGTTGGGCGGGCCATAGCAGCGGTATCTTGGAAGGCAGCGGCCCCACAGGCCGATTACTCGCGATCGATC
AAGACCCCATGGCCTTGGCGGCAGCGCGTGAACGACTTGCCCCCTATGGCGAGCGTGCGACGATTGTCCATGGCAATTAT
CGCCAAATGGCTAGCCTCGCCGCCCAACACGGCTGGCAGCAAGTCGATGGTATTCTACTCGATATTGGGGTTTCCTCGCC
GCAACTCGATTTACCCGAACGCGGTTTTTCGTTTCAGTATGATGCGCCGTTGGATATGCGCATGAATCCGACGCGCGGCG
AAAGTGCTGCCGATTTGATTGCTCAGCTTGATGAAACCAGTTTGGCTAATTTGATTTATGAATATGGTGAGGAACGCCTT
TCGCGGCGGATTGCGCGGCGGATTGTTGAGCAACGCAGCAAAAGCCCAATTACCAGCACTGCTCAATTGGCTAGTTTGGT
CAAAAGTGCTGTGGGTGGTCAGGCTGGCAAAACCCATCCCGCTACCCGAACGTTTCAAGCCTTGCGGATTGCGGTCAACG
ATGAGTTGGGGGCGTTGCGCGAAGGCTTGGCAGCGGCCACCAATTTATTAGCCCCAGGTGGGCGTTTGGCCGTGATCACC
TTCCATTCTTTAGAGGATCGGATTGTCAAAGAATGGATGCGCGATCAAGCTAGTGAATGTTTGATTCCAGCCAAGCTTGA
AATTTTGGCCTGCCCGCATAATTGTGCTGCCAACACTGGCCCACGCTCGTGTATCTACCCGGTTGGCCGTGATTGCGATT
ATGTGCCAACGCTTGAGGTGCTGAGCCGCAAGCCAATTGAGGCCACACCCGAAGAATTGAAAGCCAACCCGCGGGCGCGT
TCAGCTAAATTGCGGGTTGCCGAACGACGATTAACCAAGACGCTTGCGTCTTAA

Upstream 100 bases:

>100_bases
TTTGGTCGGCTGAGCGCTGGCAAACGGTGCTCGATAGTTTTGCCGATGAAGCGCCTGCCTTGGCTGAGCATGTCTCCGCC
TTTGGGATTTAGGCTGTTTG

Downstream 100 bases:

>100_bases
CCATAGCTCAACTGTCGGAGGATGCTTGATGGCGGTTCAATCTCAATCAATAGGTGGCCTGAGTGCCATCCGTAATCGCA
GCACCAGCCAATCAACCCGT

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MVSMHIPVLYDAALAALNLRPDGRYIDGTLGWAGHSSGILEGSGPTGRLLAIDQDPMALAAARERLAPYGERATIVHGNY
RQMASLAAQHGWQQVDGILLDIGVSSPQLDLPERGFSFQYDAPLDMRMNPTRGESAADLIAQLDETSLANLIYEYGEERL
SRRIARRIVEQRSKSPITSTAQLASLVKSAVGGQAGKTHPATRTFQALRIAVNDELGALREGLAAATNLLAPGGRLAVIT
FHSLEDRIVKEWMRDQASECLIPAKLEILACPHNCAANTGPRSCIYPVGRDCDYVPTLEVLSRKPIEATPEELKANPRAR
SAKLRVAERRLTKTLAS

Sequences:

>Translated_337_residues
MVSMHIPVLYDAALAALNLRPDGRYIDGTLGWAGHSSGILEGSGPTGRLLAIDQDPMALAAARERLAPYGERATIVHGNY
RQMASLAAQHGWQQVDGILLDIGVSSPQLDLPERGFSFQYDAPLDMRMNPTRGESAADLIAQLDETSLANLIYEYGEERL
SRRIARRIVEQRSKSPITSTAQLASLVKSAVGGQAGKTHPATRTFQALRIAVNDELGALREGLAAATNLLAPGGRLAVIT
FHSLEDRIVKEWMRDQASECLIPAKLEILACPHNCAANTGPRSCIYPVGRDCDYVPTLEVLSRKPIEATPEELKANPRAR
SAKLRVAERRLTKTLAS
>Mature_337_residues
MVSMHIPVLYDAALAALNLRPDGRYIDGTLGWAGHSSGILEGSGPTGRLLAIDQDPMALAAARERLAPYGERATIVHGNY
RQMASLAAQHGWQQVDGILLDIGVSSPQLDLPERGFSFQYDAPLDMRMNPTRGESAADLIAQLDETSLANLIYEYGEERL
SRRIARRIVEQRSKSPITSTAQLASLVKSAVGGQAGKTHPATRTFQALRIAVNDELGALREGLAAATNLLAPGGRLAVIT
FHSLEDRIVKEWMRDQASECLIPAKLEILACPHNCAANTGPRSCIYPVGRDCDYVPTLEVLSRKPIEATPEELKANPRAR
SAKLRVAERRLTKTLAS

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family

Homologues:

Organism=Homo sapiens, GI165377209, Length=348, Percent_Identity=38.5057471264368, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI165377202, Length=192, Percent_Identity=40.625, Blast_Score=133, Evalue=2e-31,
Organism=Escherichia coli, GI1786270, Length=326, Percent_Identity=46.9325153374233, Blast_Score=268, Evalue=3e-73,
Organism=Drosophila melanogaster, GI62472493, Length=344, Percent_Identity=36.9186046511628, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI28571637, Length=344, Percent_Identity=36.9186046511628, Blast_Score=182, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMH_HERA2 (A9B518)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001546283.1
- ProteinModelPortal:   A9B518
- SMR:   A9B518
- GeneID:   5735380
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_3519
- HOGENOM:   HBG302779
- OMA:   PQLDDPE
- BioCyc:   HAUR316274:HAUR_3519-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01007
- InterPro:   IPR002903
- PANTHER:   PTHR11265
- PIRSF:   PIRSF004486
- TIGRFAMs:   TIGR00006

Pfam domain/function: PF01795 Methyltransf_5

EC number: NA

Molecular weight: Translated: 36593; Mature: 36593

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: BINDING 53-53 BINDING 101-101 BINDING 108-108

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSMHIPVLYDAALAALNLRPDGRYIDGTLGWAGHSSGILEGSGPTGRLLAIDQDPMALA
CCEEECHHHHHHHHHHEECCCCCCEECCCCCCCCCCCCEEECCCCCCEEEEECCCCHHHH
AARERLAPYGERATIVHGNYRQMASLAAQHGWQQVDGILLDIGVSSPQLDLPERGFSFQY
HHHHHHCCCCCCEEEEECCHHHHHHHHHHHCHHHHCCEEEEECCCCCCCCCCCCCCCEEE
DAPLDMRMNPTRGESAADLIAQLDETSLANLIYEYGEERLSRRIARRIVEQRSKSPITST
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AQLASLVKSAVGGQAGKTHPATRTFQALRIAVNDELGALREGLAAATNLLAPGGRLAVIT
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHEEECCHHHHHHHHHHHHHHHCCCCCCEEEEE
FHSLEDRIVKEWMRDQASECLIPAKLEILACPHNCAANTGPRSCIYPVGRDCDYVPTLEV
EHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEECCCCCCCCCCCCHHH
LSRKPIEATPEELKANPRARSAKLRVAERRLTKTLAS
HCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSMHIPVLYDAALAALNLRPDGRYIDGTLGWAGHSSGILEGSGPTGRLLAIDQDPMALA
CCEEECHHHHHHHHHHEECCCCCCEECCCCCCCCCCCCEEECCCCCCEEEEECCCCHHHH
AARERLAPYGERATIVHGNYRQMASLAAQHGWQQVDGILLDIGVSSPQLDLPERGFSFQY
HHHHHHCCCCCCEEEEECCHHHHHHHHHHHCHHHHCCEEEEECCCCCCCCCCCCCCCEEE
DAPLDMRMNPTRGESAADLIAQLDETSLANLIYEYGEERLSRRIARRIVEQRSKSPITST
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AQLASLVKSAVGGQAGKTHPATRTFQALRIAVNDELGALREGLAAATNLLAPGGRLAVIT
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHEEECCHHHHHHHHHHHHHHHCCCCCCEEEEE
FHSLEDRIVKEWMRDQASECLIPAKLEILACPHNCAANTGPRSCIYPVGRDCDYVPTLEV
EHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEECCCCCCCCCCCCHHH
LSRKPIEATPEELKANPRARSAKLRVAERRLTKTLAS
HCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA