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The map label for this gene is rsbRA [H]

Identifier: 159899921

GI number: 159899921

Start: 4286733

End: 4287818

Strand: Reverse

Name: rsbRA [H]

Synonym: Haur_3404

Alternate gene names: 159899921

Gene position: 4287818-4286733 (Counterclockwise)

Preceding gene: 159899922

Following gene: 159899916

Centisome position: 67.56

GC content: 50.74

Gene sequence:

>1086_bases
ATGAAAGCACTACTGGCATGGTTAGCTCAGGTTGATCATCCGCTTGAGGATGTGCGGCGACGTGGCCAAATTATCATCAG
CGTGATGTGTGCGCTCCTCGTTATTGTTGTGATTGCCATTCCTTCCCTGCTCTTTAATCCGAAACCATTGACCTCGGCTG
TGGCTTTGGGCTTAGGCTTGGTTTTGGCGGTGGTGGTGATTCCGTTGGCGCGGCGTGGCAAAGTAACGTTTGCTGGCTGG
ATTGTGGTGATTACCACCTCCGTGATCGTCTCGATTCCGATGATGTTGCGCGGCGAAACCAGCTATACCCTAGCCTATTT
ACTGGTTCCAGTCTTGATTGCTGGGGTCGTGCTGCGCCCATGGCAAATTTTAATGGTCTTGGTTGGGGCATGGGTGATTA
TTGGCACATTGGCGTTTGTCTATCCCACAACCGATCAGGTTGCAACAACTGGTGGGGTGGTTACCCATGCGATCTTGATT
ACCATGATTGGTTCGATTATTAGTTTTGTGAATAGCCGAATTACGGTTGGGGCTTTTCATGCGGTTTCCGAAGGCCAGCG
CACGATCGAGCAAAATGCCAAACAATTAGTCGAATTAAACTCCTCGTTGGAAGCCCAAGTCCATGAGCGGACTGCCGACC
TTGAAAACGCTCTCATGAAATTGCAAGATCGGGCTAGCACCCAAGAACGCTTGCTTGATGAGATTGAACAGCAGCGTGAA
GTGATTCGCGAGATGAGCGTGCCAGTTTTGCCAGTGGCGGCCAAAGTATTGGTGATGCCATTGATTGGAGCGCTCGACAG
TGAACGCCTGACCCGCCTGCAAGAGAATGCCTTACAAGCGGTGCAGCGTCAGTCGATCAAACATTTGGTGCTGGATATTA
CCGGAGTTGTGGTGGTTGATAGCCAAGTTGCCCAAGGCTTTATTAGCGTGGTGCGCTCAGTACGCTTGCTTGGCGCTGAA
ACCATGTTGGTCGGGATTCGACCTGAAGTTGCCCAAGCCATGGTTTCGTTAGGGCTTGAATTGGATTCAATTAGTACCTC
GGCGACCTTGCAAGAAGGCTTGCAACGCATCCCCAACTATAATTAA

Upstream 100 bases:

>100_bases
TTACAGGCTAGGGTATAGTAGGGCAACTTGTTATTCTTCCCAATCTGCGGCGATGCAAATACTGGTTGTTTTAGCCCATT
GAGCCAAAAAGGGTTTTTTC

Downstream 100 bases:

>100_bases
TCGGGCTTGGTTGCTGGCTCAAACGGTTGGTCCCAACGATTGGCATAGGCTAAAGCCGCTGTGCGTTTGCGCTGCGATGA
GGTCCAATCGATCGTTGGGC

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MKALLAWLAQVDHPLEDVRRRGQIIISVMCALLVIVVIAIPSLLFNPKPLTSAVALGLGLVLAVVVIPLARRGKVTFAGW
IVVITTSVIVSIPMMLRGETSYTLAYLLVPVLIAGVVLRPWQILMVLVGAWVIIGTLAFVYPTTDQVATTGGVVTHAILI
TMIGSIISFVNSRITVGAFHAVSEGQRTIEQNAKQLVELNSSLEAQVHERTADLENALMKLQDRASTQERLLDEIEQQRE
VIREMSVPVLPVAAKVLVMPLIGALDSERLTRLQENALQAVQRQSIKHLVLDITGVVVVDSQVAQGFISVVRSVRLLGAE
TMLVGIRPEVAQAMVSLGLELDSISTSATLQEGLQRIPNYN

Sequences:

>Translated_361_residues
MKALLAWLAQVDHPLEDVRRRGQIIISVMCALLVIVVIAIPSLLFNPKPLTSAVALGLGLVLAVVVIPLARRGKVTFAGW
IVVITTSVIVSIPMMLRGETSYTLAYLLVPVLIAGVVLRPWQILMVLVGAWVIIGTLAFVYPTTDQVATTGGVVTHAILI
TMIGSIISFVNSRITVGAFHAVSEGQRTIEQNAKQLVELNSSLEAQVHERTADLENALMKLQDRASTQERLLDEIEQQRE
VIREMSVPVLPVAAKVLVMPLIGALDSERLTRLQENALQAVQRQSIKHLVLDITGVVVVDSQVAQGFISVVRSVRLLGAE
TMLVGIRPEVAQAMVSLGLELDSISTSATLQEGLQRIPNYN
>Mature_361_residues
MKALLAWLAQVDHPLEDVRRRGQIIISVMCALLVIVVIAIPSLLFNPKPLTSAVALGLGLVLAVVVIPLARRGKVTFAGW
IVVITTSVIVSIPMMLRGETSYTLAYLLVPVLIAGVVLRPWQILMVLVGAWVIIGTLAFVYPTTDQVATTGGVVTHAILI
TMIGSIISFVNSRITVGAFHAVSEGQRTIEQNAKQLVELNSSLEAQVHERTADLENALMKLQDRASTQERLLDEIEQQRE
VIREMSVPVLPVAAKVLVMPLIGALDSERLTRLQENALQAVQRQSIKHLVLDITGVVVVDSQVAQGFISVVRSVRLLGAE
TMLVGIRPEVAQAMVSLGLELDSISTSATLQEGLQRIPNYN

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 39155; Mature: 39155

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALLAWLAQVDHPLEDVRRRGQIIISVMCALLVIVVIAIPSLLFNPKPLTSAVALGLGL
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VLAVVVIPLARRGKVTFAGWIVVITTSVIVSIPMMLRGETSYTLAYLLVPVLIAGVVLRP
HHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
WQILMVLVGAWVIIGTLAFVYPTTDQVATTGGVVTHAILITMIGSIISFVNSRITVGAFH
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AVSEGQRTIEQNAKQLVELNSSLEAQVHERTADLENALMKLQDRASTQERLLDEIEQQRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VIREMSVPVLPVAAKVLVMPLIGALDSERLTRLQENALQAVQRQSIKHLVLDITGVVVVD
HHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
SQVAQGFISVVRSVRLLGAETMLVGIRPEVAQAMVSLGLELDSISTSATLQEGLQRIPNY
HHHHHHHHHHHHHHHHHCHHHHEEECCHHHHHHHHHHCCCHHHCCHHHHHHHHHHHCCCC
N
C
>Mature Secondary Structure
MKALLAWLAQVDHPLEDVRRRGQIIISVMCALLVIVVIAIPSLLFNPKPLTSAVALGLGL
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VLAVVVIPLARRGKVTFAGWIVVITTSVIVSIPMMLRGETSYTLAYLLVPVLIAGVVLRP
HHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
WQILMVLVGAWVIIGTLAFVYPTTDQVATTGGVVTHAILITMIGSIISFVNSRITVGAFH
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AVSEGQRTIEQNAKQLVELNSSLEAQVHERTADLENALMKLQDRASTQERLLDEIEQQRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VIREMSVPVLPVAAKVLVMPLIGALDSERLTRLQENALQAVQRQSIKHLVLDITGVVVVD
HHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
SQVAQGFISVVRSVRLLGAETMLVGIRPEVAQAMVSLGLELDSISTSATLQEGLQRIPNY
HHHHHHHHHHHHHHHHHCHHHHEEECCHHHHHHHHHHCCCHHHCCHHHHHHHHHHHCCCC
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]