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The map label for this gene is hup [H]

Identifier: 159899915

GI number: 159899915

Start: 4280320

End: 4280598

Strand: Reverse

Name: hup [H]

Synonym: Haur_3398

Alternate gene names: 159899915

Gene position: 4280598-4280320 (Counterclockwise)

Preceding gene: 159899916

Following gene: 159899914

Centisome position: 67.45

GC content: 53.41

Gene sequence:

>279_bases
ATGCATCAATCGGATTTGATCAAGGCCATTGCGGAAAAATCAGGTTTGAGCCAAGCCCAAGCTGGCAAAGCAGTTAACGC
CTTGCTCGAAAGCATCACCGAAGCGTTGGCTGCTGGCGATCGGGTCGTCTTGACTGGCTTCGGGACGTTTGAAGTCCGCG
AACGCCAAGCTCGTACTGGCTTCAACCCCAAAACCCGTGAGCCATTGGAAATTCCTGCTACCCGCGCCCCAGCATTCTCG
GCTGGTAGCAACTTGAAAAAGGCTGTGACCGAGAAATAA

Upstream 100 bases:

>100_bases
TAGGTGATATCGCGAATGCTTGTGGTATTACGAGGATACTAAAGCCATGCGGCTGTCTTTCAATTCTGGTGAAGACAGGT
AGTGTAAGGAGTAACTCCAA

Downstream 100 bases:

>100_bases
GCTTGGTCACCCCTAAAAACCACGGCTAGGCCAAGCGCTTAGCTGTGGTTTTTTTAACTTGAAAATAGAACAAATGTTTT
ATATAATCAGCTGTTGTGTT

Product: histone family protein DNA-binding protein

Products: NA

Alternate protein names: DNA-binding protein II; HB [H]

Number of amino acids: Translated: 92; Mature: 92

Protein sequence:

>92_residues
MHQSDLIKAIAEKSGLSQAQAGKAVNALLESITEALAAGDRVVLTGFGTFEVRERQARTGFNPKTREPLEIPATRAPAFS
AGSNLKKAVTEK

Sequences:

>Translated_92_residues
MHQSDLIKAIAEKSGLSQAQAGKAVNALLESITEALAAGDRVVLTGFGTFEVRERQARTGFNPKTREPLEIPATRAPAFS
AGSNLKKAVTEK
>Mature_92_residues
MHQSDLIKAIAEKSGLSQAQAGKAVNALLESITEALAAGDRVVLTGFGTFEVRERQARTGFNPKTREPLEIPATRAPAFS
AGSNLKKAVTEK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=50, Blast_Score=91, Evalue=2e-20,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=49.438202247191, Blast_Score=83, Evalue=4e-18,
Organism=Escherichia coli, GI1788005, Length=89, Percent_Identity=37.0786516853933, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI1787141, Length=87, Percent_Identity=35.632183908046, Blast_Score=59, Evalue=6e-11,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9765; Mature: 9765

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQSDLIKAIAEKSGLSQAQAGKAVNALLESITEALAAGDRVVLTGFGTFEVRERQARTG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCC
FNPKTREPLEIPATRAPAFSAGSNLKKAVTEK
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MHQSDLIKAIAEKSGLSQAQAGKAVNALLESITEALAAGDRVVLTGFGTFEVRERQARTG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCC
FNPKTREPLEIPATRAPAFSAGSNLKKAVTEK
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1644313 [H]