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The map label for this gene is bcp [C]

Identifier: 159899911

GI number: 159899911

Start: 4276816

End: 4277271

Strand: Reverse

Name: bcp [C]

Synonym: Haur_3394

Alternate gene names: 159899911

Gene position: 4277271-4276816 (Counterclockwise)

Preceding gene: 159899914

Following gene: 159899897

Centisome position: 67.39

GC content: 48.9

Gene sequence:

>456_bases
GTGGATAGTACCACCCTCAAAGTGGGCGATCAAGCCCCCGATTGGACGTTAACTGGAACTGAAGGCGATGTACACTTGGC
CAGCTTCCAGGGCCAAAAAAACGTTGTGCTGTTGTTTTATCCATTAGATTTCAGCCCTGTTTGTTCGCTGCAATTGCCCA
GCTATCAAGCTCGCAAGCCTGAGTTTGATCAACGCGATACCGAGATTTTTGGCATTAGCACCGATAGCAAGTGGTCGCAT
AAAGCCTTTTCCGAGCAACTTGGGCTGGAATATCAGTTGCTGAGCGATTATCAGCGCCATGTTTCCGAGGCCTATGGCGT
GTTGCGACCTGAAGGTTTTACCAATCGAGCGGTCTTTGTCATTGATAAAGCTGGCATCATTCGCCATGTTTCGGTGACTA
ACCCCGGCCAACAACCCGACCAAAATGAGGTCATTCGGGTTTTAGAAACGTTGTAA

Upstream 100 bases:

>100_bases
AATGATTGTTGATATTCGACTTGTCATAATTCCTCTCACCTAATCCCAATGCGGAGTATAATAGAAACTTCAGAGTGTGT
CATTTTAAGGAGCGCTGCGC

Downstream 100 bases:

>100_bases
CAATCATAAAGCTGGGGCTGCGGGAATTCGCCGTCAATTGACATGCCCTCACCCCCTAGCCCCCTCTCCCGCATGCGAGG
CGAGGGGGAAGCAGCCTAGC

Product: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MDSTTLKVGDQAPDWTLTGTEGDVHLASFQGQKNVVLLFYPLDFSPVCSLQLPSYQARKPEFDQRDTEIFGISTDSKWSH
KAFSEQLGLEYQLLSDYQRHVSEAYGVLRPEGFTNRAVFVIDKAGIIRHVSVTNPGQQPDQNEVIRVLETL

Sequences:

>Translated_151_residues
MDSTTLKVGDQAPDWTLTGTEGDVHLASFQGQKNVVLLFYPLDFSPVCSLQLPSYQARKPEFDQRDTEIFGISTDSKWSH
KAFSEQLGLEYQLLSDYQRHVSEAYGVLRPEGFTNRAVFVIDKAGIIRHVSVTNPGQQPDQNEVIRVLETL
>Mature_151_residues
MDSTTLKVGDQAPDWTLTGTEGDVHLASFQGQKNVVLLFYPLDFSPVCSLQLPSYQARKPEFDQRDTEIFGISTDSKWSH
KAFSEQLGLEYQLLSDYQRHVSEAYGVLRPEGFTNRAVFVIDKAGIIRHVSVTNPGQQPDQNEVIRVLETL

Specific function: Reduces peroxides. May play an important role in eliminating peroxides generated during metabolism [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32189392, Length=163, Percent_Identity=34.3558282208589, Blast_Score=93, Evalue=7e-20,
Organism=Homo sapiens, GI4505591, Length=164, Percent_Identity=32.9268292682927, Blast_Score=89, Evalue=1e-18,
Organism=Homo sapiens, GI32455266, Length=164, Percent_Identity=32.9268292682927, Blast_Score=89, Evalue=1e-18,
Organism=Homo sapiens, GI32455264, Length=164, Percent_Identity=32.9268292682927, Blast_Score=89, Evalue=1e-18,
Organism=Homo sapiens, GI32483377, Length=144, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI5802974, Length=143, Percent_Identity=33.5664335664336, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI5453549, Length=157, Percent_Identity=31.8471337579618, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1788825, Length=133, Percent_Identity=35.3383458646617, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1786822, Length=119, Percent_Identity=30.2521008403361, Blast_Score=66, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17554494, Length=141, Percent_Identity=32.6241134751773, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32565831, Length=156, Percent_Identity=32.0512820512821, Blast_Score=76, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI193204376, Length=156, Percent_Identity=32.0512820512821, Blast_Score=76, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6319407, Length=166, Percent_Identity=27.710843373494, Blast_Score=79, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320661, Length=155, Percent_Identity=32.9032258064516, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323613, Length=157, Percent_Identity=31.2101910828025, Blast_Score=71, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21357347, Length=158, Percent_Identity=32.9113924050633, Blast_Score=83, Evalue=8e-17,
Organism=Drosophila melanogaster, GI17738015, Length=160, Percent_Identity=33.125, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24656348, Length=127, Percent_Identity=35.4330708661417, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17864676, Length=127, Percent_Identity=35.4330708661417, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24581278, Length=166, Percent_Identity=28.9156626506024, Blast_Score=76, Evalue=7e-15,
Organism=Drosophila melanogaster, GI17157991, Length=143, Percent_Identity=32.1678321678322, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24641739, Length=143, Percent_Identity=32.1678321678322, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: 920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 17017; Mature: 17017

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSTTLKVGDQAPDWTLTGTEGDVHLASFQGQKNVVLLFYPLDFSPVCSLQLPSYQARKP
CCCCEEEECCCCCCEEEECCCCCEEEEEECCCCCEEEEEECCCCCCEEEEECCCCCCCCC
EFDQRDTEIFGISTDSKWSHKAFSEQLGLEYQLLSDYQRHVSEAYGVLRPEGFTNRAVFV
CCCCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
IDKAGIIRHVSVTNPGQQPDQNEVIRVLETL
EECCCEEEEEEECCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MDSTTLKVGDQAPDWTLTGTEGDVHLASFQGQKNVVLLFYPLDFSPVCSLQLPSYQARKP
CCCCEEEECCCCCCEEEECCCCCEEEEEECCCCCEEEEEECCCCCCEEEEECCCCCCCCC
EFDQRDTEIFGISTDSKWSHKAFSEQLGLEYQLLSDYQRHVSEAYGVLRPEGFTNRAVFV
CCCCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
IDKAGIIRHVSVTNPGQQPDQNEVIRVLETL
EECCCEEEEEEECCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]