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The map label for this gene is phoR [H]

Identifier: 159899882

GI number: 159899882

Start: 4243949

End: 4246150

Strand: Reverse

Name: phoR [H]

Synonym: Haur_3365

Alternate gene names: 159899882

Gene position: 4246150-4243949 (Counterclockwise)

Preceding gene: 159899888

Following gene: 159899881

Centisome position: 66.9

GC content: 49.91

Gene sequence:

>2202_bases
GTGTTGCGATGGGCTACGATGAAATCATTAATTGCGCATAAATTAAATCGTTGGTTCATGCTAGCAGCACTTGTGATTAT
CGTCAATGGCCTCCTTTCGTGGCAATATCTCCAAACGATTCAAGCCAATAATGCTAGTGTGATCGAATCGGAAACCATGA
CCAATCGTTTGGATCGGCTGTTATCGTTGTTGAAAGACGCTGAAACCGGCCAACGTGGGTTTATTATCACTGGCAGCGAA
CAATATTTAGCTCCCTACCAAACCGCCCAAACCGAACTCCCTAGCCTGCTTGCTGAGATTGAAGCCTACAGCAGTCAACG
CCCATTGTTTATCGAACGCTTACCTGAGCTGAAAACCTTGATCGCTGAGCAGCAACAGGAGCTGAGCACGACGATTGATT
TGCGGCGCAGCCAAGGCTTTGAAGCCGCCCAGGCGATTGTGCTGGAAAATCAGGGCAAGCAGCACATGGATAGCATTCGT
CAAATTATCGATCAATTGCTTGATCGCGAAAATATTCGGGCGCTTGATAGAGCGGCTCAGACCAAACTCAATGTGCAACG
AGCAGGCCTTGCGCTGGCCTTTGCTACTTTGGTTGCCACAGGCTTTGTGATTGGCACAATGGCCTTAACCGAGCGCGATG
TGCGTCGCCGTGAGTTGGCTGCCAACGAGTTGCGCAACCAGCGCGAATGGTTTGCAGTTACCCTCGCTAGTATCGGCGAT
GCGGTGCTGACCACCGATATCGATGGCAAAATTAGCTTTATGAACCATATTGCCACGACGATTACCGGCTGGCCTGAGCA
ACAAGCGCTTGGTCAATCAATTCATACAGTGGCAGCAATTTTTGATCCAATAACCAAGCAGGAGCTGGCCCATCCGGTCA
ATACCGCTCTCGCACAGCGTCAAATCGTCACCTTGAGCAATTCGGTGGTGATGCGCCAAGGCAATGGCTATGTGGCAATC
GAAGATAGCGCCGCGCCAATTTACGACCGCGAACAGCAGGTGATTGGCGCGGTGATGGTTTTTCGTGATGTAAGCGAACG
CTATCGCGATGAGTTTGGCCAACGCTTGTTACGAACATTACATAATCGATTGGCGGCGACGATTGATTTAGCGCAAGTGC
TAGAAACCAGCACTGCTGTGCCAACTCCCAGTTTTAGCGCTGCCTGCGGTTTATATTTGCTGCTAGATGCCGATGAAGAG
CCTCTGAGCAGCTATAGCAGTGCCCATGAGCCATTGCTCAATTGGCAGCAACACCCAGCTTTTGCCGCCGCGCTAGCTAA
CAGCCAAGCCCAAATTATCGATCAAGCCTTGCCTGAGCCATATCACTCGGCAATTATCATCCCTTTTCGCGATCAACATC
AGCTCAGCGGGGCAATCGTCTTTTTGCACGATCAACATCGATTTGACCAAATTGATGTTGAATTGGCCGAGGAGCTAAGT
CAGCGGATGGTCTTGGCGATTGAGCAGGCCTATCTCTATCGTCAAGCCCAAAATGCTGTGCGTTTGCGTGATGTCTTTTT
ATCGATTGCCTCGCACGAGTTGAAAAACCCATTAACCACCTTGCTTGGTCAATCGCAATTGAGTTTGCGCCGCCTAGAAC
GACTGAATTTGGTCGATGAGCGACTTCAGCGTTCGCTGCAAGCGATTGAAGCTCAGGCCAGCCGCATGAATAAAATGGTG
ACCGCCTTGCTCGATGTTTCACGCATCGAAACAGGCCAGCTCGATATTCAGCATGATCAAATCGATTTGGCTCAGCTTTT
ACAACAATTGGTCAACGATTTAGCCATCACGATCGATCATCACCAGCTTAGTTACCACTGCACGAGCAGCCAGCCTATCC
AAGTGGTGGGCGACCCAATTCGCTTAGAGCAAGTATTTGTCAATTTGATCAACAATGCCATGAAATATAGCCCCGAACAA
ACCGAAGTGCTGGTACGTGCTGATCGGAATGCCCAACAAGCGATCGTCCAGATTCGCGATCATGGCATTGGCATTCCAGC
AGAATCGATCCCCAACCTCTTTACCCGTTTTTATCGGGCCAGCAATGCTGCGCGTAGCCATGTAGCAGGGCTAGGCATTG
GCCTATTTGTGGTCAAAGAAATTGTCGATCTGCATGGTGGCAGCATTGAAGTGAGCAGCCAAGTTGGCCAAGGTAGCCTG
TTCACGGTGTATTTACCGCTGCAAACTGGAAATCCTCAATAA

Upstream 100 bases:

>100_bases
TTTGATTGCCATTGGTTGTCGTAATGTTACGGCAGCCATCAAAGCTTGCTAGGCAATGATTCGGTAGAACTGCTGGCATA
TTGAACTTTGGGGTTAGATT

Downstream 100 bases:

>100_bases
ACTTCGATTATTAACGAATATAAACAATATGTCATAGGGGACAATCGCTAATTGTCCCTCTACAATGTCTGCATGGCATG
GTACATTTAGTTCCACAAAC

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 733; Mature: 733

Protein sequence:

>733_residues
MLRWATMKSLIAHKLNRWFMLAALVIIVNGLLSWQYLQTIQANNASVIESETMTNRLDRLLSLLKDAETGQRGFIITGSE
QYLAPYQTAQTELPSLLAEIEAYSSQRPLFIERLPELKTLIAEQQQELSTTIDLRRSQGFEAAQAIVLENQGKQHMDSIR
QIIDQLLDRENIRALDRAAQTKLNVQRAGLALAFATLVATGFVIGTMALTERDVRRRELAANELRNQREWFAVTLASIGD
AVLTTDIDGKISFMNHIATTITGWPEQQALGQSIHTVAAIFDPITKQELAHPVNTALAQRQIVTLSNSVVMRQGNGYVAI
EDSAAPIYDREQQVIGAVMVFRDVSERYRDEFGQRLLRTLHNRLAATIDLAQVLETSTAVPTPSFSAACGLYLLLDADEE
PLSSYSSAHEPLLNWQQHPAFAAALANSQAQIIDQALPEPYHSAIIIPFRDQHQLSGAIVFLHDQHRFDQIDVELAEELS
QRMVLAIEQAYLYRQAQNAVRLRDVFLSIASHELKNPLTTLLGQSQLSLRRLERLNLVDERLQRSLQAIEAQASRMNKMV
TALLDVSRIETGQLDIQHDQIDLAQLLQQLVNDLAITIDHHQLSYHCTSSQPIQVVGDPIRLEQVFVNLINNAMKYSPEQ
TEVLVRADRNAQQAIVQIRDHGIGIPAESIPNLFTRFYRASNAARSHVAGLGIGLFVVKEIVDLHGGSIEVSSQVGQGSL
FTVYLPLQTGNPQ

Sequences:

>Translated_733_residues
MLRWATMKSLIAHKLNRWFMLAALVIIVNGLLSWQYLQTIQANNASVIESETMTNRLDRLLSLLKDAETGQRGFIITGSE
QYLAPYQTAQTELPSLLAEIEAYSSQRPLFIERLPELKTLIAEQQQELSTTIDLRRSQGFEAAQAIVLENQGKQHMDSIR
QIIDQLLDRENIRALDRAAQTKLNVQRAGLALAFATLVATGFVIGTMALTERDVRRRELAANELRNQREWFAVTLASIGD
AVLTTDIDGKISFMNHIATTITGWPEQQALGQSIHTVAAIFDPITKQELAHPVNTALAQRQIVTLSNSVVMRQGNGYVAI
EDSAAPIYDREQQVIGAVMVFRDVSERYRDEFGQRLLRTLHNRLAATIDLAQVLETSTAVPTPSFSAACGLYLLLDADEE
PLSSYSSAHEPLLNWQQHPAFAAALANSQAQIIDQALPEPYHSAIIIPFRDQHQLSGAIVFLHDQHRFDQIDVELAEELS
QRMVLAIEQAYLYRQAQNAVRLRDVFLSIASHELKNPLTTLLGQSQLSLRRLERLNLVDERLQRSLQAIEAQASRMNKMV
TALLDVSRIETGQLDIQHDQIDLAQLLQQLVNDLAITIDHHQLSYHCTSSQPIQVVGDPIRLEQVFVNLINNAMKYSPEQ
TEVLVRADRNAQQAIVQIRDHGIGIPAESIPNLFTRFYRASNAARSHVAGLGIGLFVVKEIVDLHGGSIEVSSQVGQGSL
FTVYLPLQTGNPQ
>Mature_733_residues
MLRWATMKSLIAHKLNRWFMLAALVIIVNGLLSWQYLQTIQANNASVIESETMTNRLDRLLSLLKDAETGQRGFIITGSE
QYLAPYQTAQTELPSLLAEIEAYSSQRPLFIERLPELKTLIAEQQQELSTTIDLRRSQGFEAAQAIVLENQGKQHMDSIR
QIIDQLLDRENIRALDRAAQTKLNVQRAGLALAFATLVATGFVIGTMALTERDVRRRELAANELRNQREWFAVTLASIGD
AVLTTDIDGKISFMNHIATTITGWPEQQALGQSIHTVAAIFDPITKQELAHPVNTALAQRQIVTLSNSVVMRQGNGYVAI
EDSAAPIYDREQQVIGAVMVFRDVSERYRDEFGQRLLRTLHNRLAATIDLAQVLETSTAVPTPSFSAACGLYLLLDADEE
PLSSYSSAHEPLLNWQQHPAFAAALANSQAQIIDQALPEPYHSAIIIPFRDQHQLSGAIVFLHDQHRFDQIDVELAEELS
QRMVLAIEQAYLYRQAQNAVRLRDVFLSIASHELKNPLTTLLGQSQLSLRRLERLNLVDERLQRSLQAIEAQASRMNKMV
TALLDVSRIETGQLDIQHDQIDLAQLLQQLVNDLAITIDHHQLSYHCTSSQPIQVVGDPIRLEQVFVNLINNAMKYSPEQ
TEVLVRADRNAQQAIVQIRDHGIGIPAESIPNLFTRFYRASNAARSHVAGLGIGLFVVKEIVDLHGGSIEVSSQVGQGSL
FTVYLPLQTGNPQ

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=272, Percent_Identity=30.1470588235294, Blast_Score=135, Evalue=9e-33,
Organism=Escherichia coli, GI1789149, Length=274, Percent_Identity=32.8467153284672, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=31.2775330396476, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786912, Length=308, Percent_Identity=28.2467532467532, Blast_Score=110, Evalue=4e-25,
Organism=Escherichia coli, GI48994928, Length=235, Percent_Identity=28.936170212766, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=28.0172413793103, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=32.2727272727273, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788713, Length=241, Percent_Identity=27.3858921161826, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI87081816, Length=270, Percent_Identity=26.2962962962963, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788279, Length=221, Percent_Identity=27.1493212669683, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1790346, Length=224, Percent_Identity=28.125, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1790861, Length=199, Percent_Identity=27.1356783919598, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1788393, Length=228, Percent_Identity=27.1929824561404, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1789403, Length=214, Percent_Identity=32.2429906542056, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790300, Length=241, Percent_Identity=28.6307053941909, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87082128, Length=235, Percent_Identity=23.8297872340426, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1788549, Length=244, Percent_Identity=28.6885245901639, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787894, Length=226, Percent_Identity=26.9911504424779, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 81897; Mature: 81897

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRWATMKSLIAHKLNRWFMLAALVIIVNGLLSWQYLQTIQANNASVIESETMTNRLDRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHH
LSLLKDAETGQRGFIITGSEQYLAPYQTAQTELPSLLAEIEAYSSQRPLFIERLPELKTL
HHHHHCCCCCCCCEEEECCCHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
IAEQQQELSTTIDLRRSQGFEAAQAIVLENQGKQHMDSIRQIIDQLLDRENIRALDRAAQ
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
TKLNVQRAGLALAFATLVATGFVIGTMALTERDVRRRELAANELRNQREWFAVTLASIGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
AVLTTDIDGKISFMNHIATTITGWPEQQALGQSIHTVAAIFDPITKQELAHPVNTALAQR
EEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIVTLSNSVVMRQGNGYVAIEDSAAPIYDREQQVIGAVMVFRDVSERYRDEFGQRLLRTL
HHEEECCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HNRLAATIDLAQVLETSTAVPTPSFSAACGLYLLLDADEEPLSSYSSAHEPLLNWQQHPA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCH
FAAALANSQAQIIDQALPEPYHSAIIIPFRDQHQLSGAIVFLHDQHRFDQIDVELAEELS
HHHHHHCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
QRMVLAIEQAYLYRQAQNAVRLRDVFLSIASHELKNPLTTLLGQSQLSLRRLERLNLVDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHH
RLQRSLQAIEAQASRMNKMVTALLDVSRIETGQLDIQHDQIDLAQLLQQLVNDLAITIDH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHEEEEEC
HQLSYHCTSSQPIQVVGDPIRLEQVFVNLINNAMKYSPEQTEVLVRADRNAQQAIVQIRD
CEEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCHHHHHHHHHH
HGIGIPAESIPNLFTRFYRASNAARSHVAGLGIGLFVVKEIVDLHGGSIEVSSQVGQGSL
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCE
FTVYLPLQTGNPQ
EEEEEEECCCCCC
>Mature Secondary Structure
MLRWATMKSLIAHKLNRWFMLAALVIIVNGLLSWQYLQTIQANNASVIESETMTNRLDRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHH
LSLLKDAETGQRGFIITGSEQYLAPYQTAQTELPSLLAEIEAYSSQRPLFIERLPELKTL
HHHHHCCCCCCCCEEEECCCHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
IAEQQQELSTTIDLRRSQGFEAAQAIVLENQGKQHMDSIRQIIDQLLDRENIRALDRAAQ
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
TKLNVQRAGLALAFATLVATGFVIGTMALTERDVRRRELAANELRNQREWFAVTLASIGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
AVLTTDIDGKISFMNHIATTITGWPEQQALGQSIHTVAAIFDPITKQELAHPVNTALAQR
EEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIVTLSNSVVMRQGNGYVAIEDSAAPIYDREQQVIGAVMVFRDVSERYRDEFGQRLLRTL
HHEEECCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HNRLAATIDLAQVLETSTAVPTPSFSAACGLYLLLDADEEPLSSYSSAHEPLLNWQQHPA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCH
FAAALANSQAQIIDQALPEPYHSAIIIPFRDQHQLSGAIVFLHDQHRFDQIDVELAEELS
HHHHHHCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
QRMVLAIEQAYLYRQAQNAVRLRDVFLSIASHELKNPLTTLLGQSQLSLRRLERLNLVDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHH
RLQRSLQAIEAQASRMNKMVTALLDVSRIETGQLDIQHDQIDLAQLLQQLVNDLAITIDH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHEEEEEC
HQLSYHCTSSQPIQVVGDPIRLEQVFVNLINNAMKYSPEQTEVLVRADRNAQQAIVQIRD
CEEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCHHHHHHHHHH
HGIGIPAESIPNLFTRFYRASNAARSHVAGLGIGLFVVKEIVDLHGGSIEVSSQVGQGSL
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCE
FTVYLPLQTGNPQ
EEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]