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The map label for this gene is fprA [H]

Identifier: 159899785

GI number: 159899785

Start: 4130886

End: 4132298

Strand: Reverse

Name: fprA [H]

Synonym: Haur_3267

Alternate gene names: 159899785

Gene position: 4132298-4130886 (Counterclockwise)

Preceding gene: 159899786

Following gene: 159899784

Centisome position: 65.11

GC content: 51.88

Gene sequence:

>1413_bases
ATGACAACTGTGGGAACTGAAGCGCAGCCATTACGGGTTGCGATCATTGGTTCTGGGCCATCGGCATTTTATGCGGCGGA
TCACTTGCTCAAACAAAGCGATCTGGTTGTAGAAGTTGATATGTTCGACCGTTTGCCAACGCCATTTGGTTTGGTTCGCG
GTGGGGTCGCTCCTGATCATCAGAAGATCAAGACCGTCACCAAGGCCTTTAATTTGGTTGCCAAAAATCCTCGTTTTCGC
TTTTTTGGCTATGTGGAATATGGTAAAGATCTGAGCCACGCCGATTTAGTTGAACACTACCATCAAATTTTATATGCCAC
AGGTGCGCAAAGTGATCGCCATATGGGGATTCCTGGCGAGGATCTGACTAATAGTTTTCCGGCGACCGCCTTTGTGGCTT
GGTACAACGGCCATCCCGATTATCGTCATCTGCAATTCGATCTCTCGCAAGAGCGGGTGGCGGTAGTTGGGGTTGGCAAC
GTGGCAATTGATGTAGCACGGATTTTGTGCCTCTCGCACGAAGAATTAGCGCGTACCGACATCGCCGACCATGCTTTGGA
AGCACTCAGCAAAAGCAATATTAAAGAAGTGTATTTGCTGGGGCGACGTGGGCCAGCTCAAGCAGCCTTCACCACTCCCG
AAGTCAAAGAATTGGGCGAGCTGGAAGAAGCCGATGTGGTGGCGATTCCCAGCGAAGTTGCCCTCGACGATGTGAGCCGC
GCCGATCTAGAGGCTGGTGGCGATAAAGCTGCTCAGAAGAAGGTCGAATTGCTGCAAGGCTACGCTCAACGTGCGCCCGA
AGGCAAAAAACGCCGCTTGATTTTCCGCTTCTTGGTTAGCCCAACCGAAGTTTTAGGCGATAGCGATGGGCGGGTAGCAG
GCTTGCGTTTGGCTAAAAACGAACTTTACGCCAGCGAATCGGGCAGCATCGCCTCACGCGCAACTGGCGAAACCGAAGAT
TTGCCCGTTGGCTTGGTTTTCCGTTCGGTTGGCTATCGTGGTTCACCATTGGTTGATGTACCATTCAATGAACGCTGGGG
AACCTTCCTCAACCAAAAAGGCCGCATTATCGACCCAACCAGCCAACAGCCCAAAATTGGCGAATATACTGCTGGCTGGA
TCAAGCGCGGCCCGAGTGGCGTGATTGGCACCAACAAGCCCGATGCAGTTGAAACTGTCCAATGTATGTTGGAAGATTTG
GCGACAGGGCAAGTGCTCAATCCTAGCCATGCCGAGCGCGAAAGCATTGAAAAATTGGTGCAAGAACGCCAACCCAACTA
TGTAACCTTTGCCGATTGGCAACACCTCGACGAGATTGAGGTTGCCAATGGCGCGGCTACAGGTCGGCCACGGGTCAAAT
TCACCCGCATCGAAGATATGTTGGCTGCACTTGGCAAAAATGTAACTGCCTAA

Upstream 100 bases:

>100_bases
CGATGTGGTCAAGGCACAACTTGGGGAATATGAAGGTAAGCTCGATACCCTCGAAACTCAAATTATCGAAGAGGGCTAGA
CGCTCAAAAGGATTGCGATC

Downstream 100 bases:

>100_bases
AATTACGCAACTTTAAAAACAAAGCCCACAGCTGAGTAATATCAGGTGTGGGTTTGTCTTTTAGGGGTCAGGGGCTGGGG
ATCAGGGGTCAGTTAAGTTG

Product: ferredoxin--NADP(+) reductase

Products: NA

Alternate protein names: NFR [H]

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MTTVGTEAQPLRVAIIGSGPSAFYAADHLLKQSDLVVEVDMFDRLPTPFGLVRGGVAPDHQKIKTVTKAFNLVAKNPRFR
FFGYVEYGKDLSHADLVEHYHQILYATGAQSDRHMGIPGEDLTNSFPATAFVAWYNGHPDYRHLQFDLSQERVAVVGVGN
VAIDVARILCLSHEELARTDIADHALEALSKSNIKEVYLLGRRGPAQAAFTTPEVKELGELEEADVVAIPSEVALDDVSR
ADLEAGGDKAAQKKVELLQGYAQRAPEGKKRRLIFRFLVSPTEVLGDSDGRVAGLRLAKNELYASESGSIASRATGETED
LPVGLVFRSVGYRGSPLVDVPFNERWGTFLNQKGRIIDPTSQQPKIGEYTAGWIKRGPSGVIGTNKPDAVETVQCMLEDL
ATGQVLNPSHAERESIEKLVQERQPNYVTFADWQHLDEIEVANGAATGRPRVKFTRIEDMLAALGKNVTA

Sequences:

>Translated_470_residues
MTTVGTEAQPLRVAIIGSGPSAFYAADHLLKQSDLVVEVDMFDRLPTPFGLVRGGVAPDHQKIKTVTKAFNLVAKNPRFR
FFGYVEYGKDLSHADLVEHYHQILYATGAQSDRHMGIPGEDLTNSFPATAFVAWYNGHPDYRHLQFDLSQERVAVVGVGN
VAIDVARILCLSHEELARTDIADHALEALSKSNIKEVYLLGRRGPAQAAFTTPEVKELGELEEADVVAIPSEVALDDVSR
ADLEAGGDKAAQKKVELLQGYAQRAPEGKKRRLIFRFLVSPTEVLGDSDGRVAGLRLAKNELYASESGSIASRATGETED
LPVGLVFRSVGYRGSPLVDVPFNERWGTFLNQKGRIIDPTSQQPKIGEYTAGWIKRGPSGVIGTNKPDAVETVQCMLEDL
ATGQVLNPSHAERESIEKLVQERQPNYVTFADWQHLDEIEVANGAATGRPRVKFTRIEDMLAALGKNVTA
>Mature_469_residues
TTVGTEAQPLRVAIIGSGPSAFYAADHLLKQSDLVVEVDMFDRLPTPFGLVRGGVAPDHQKIKTVTKAFNLVAKNPRFRF
FGYVEYGKDLSHADLVEHYHQILYATGAQSDRHMGIPGEDLTNSFPATAFVAWYNGHPDYRHLQFDLSQERVAVVGVGNV
AIDVARILCLSHEELARTDIADHALEALSKSNIKEVYLLGRRGPAQAAFTTPEVKELGELEEADVVAIPSEVALDDVSRA
DLEAGGDKAAQKKVELLQGYAQRAPEGKKRRLIFRFLVSPTEVLGDSDGRVAGLRLAKNELYASESGSIASRATGETEDL
PVGLVFRSVGYRGSPLVDVPFNERWGTFLNQKGRIIDPTSQQPKIGEYTAGWIKRGPSGVIGTNKPDAVETVQCMLEDLA
TGQVLNPSHAERESIEKLVQERQPNYVTFADWQHLDEIEVANGAATGRPRVKFTRIEDMLAALGKNVTA

Specific function: May serve as electron transfer protein and supply electrons to P450 systems [H]

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 1 family [H]

Homologues:

Organism=Homo sapiens, GI111118981, Length=470, Percent_Identity=39.5744680851064, Blast_Score=316, Evalue=3e-86,
Organism=Homo sapiens, GI111118983, Length=476, Percent_Identity=39.0756302521008, Blast_Score=310, Evalue=2e-84,
Organism=Caenorhabditis elegans, GI17543860, Length=459, Percent_Identity=31.1546840958606, Blast_Score=232, Evalue=3e-61,
Organism=Saccharomyces cerevisiae, GI6320584, Length=486, Percent_Identity=29.8353909465021, Blast_Score=212, Evalue=1e-55,
Organism=Drosophila melanogaster, GI17137178, Length=458, Percent_Identity=36.2445414847162, Blast_Score=275, Evalue=4e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR021163
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 51442; Mature: 51310

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVGTEAQPLRVAIIGSGPSAFYAADHLLKQSDLVVEVDMFDRLPTPFGLVRGGVAPDH
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEEHHHCCCCCHHHHCCCCCCCH
QKIKTVTKAFNLVAKNPRFRFFGYVEYGKDLSHADLVEHYHQILYATGAQSDRHMGIPGE
HHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCH
DLTNSFPATAFVAWYNGHPDYRHLQFDLSQERVAVVGVGNVAIDVARILCLSHEELARTD
HHCCCCCCEEEEEEECCCCCCEEEEEECCCCCEEEEECCHHHHHHHHHHHHCHHHHHHHH
IADHALEALSKSNIKEVYLLGRRGPAQAAFTTPEVKELGELEEADVVAIPSEVALDDVSR
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHCCCCCCCEEECCCHHHHHHHHH
ADLEAGGDKAAQKKVELLQGYAQRAPEGKKRRLIFRFLVSPTEVLGDSDGRVAGLRLAKN
HHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHCCCCCCEEEEEEEHH
ELYASESGSIASRATGETEDLPVGLVFRSVGYRGSPLVDVPFNERWGTFLNQKGRIIDPT
HHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEECCCCCHHHHHHCCCCCEECCC
SQQPKIGEYTAGWIKRGPSGVIGTNKPDAVETVQCMLEDLATGQVLNPSHAERESIEKLV
CCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
QERQPNYVTFADWQHLDEIEVANGAATGRPRVKFTRIEDMLAALGKNVTA
HHCCCCEEEECCCCCCCCEEECCCCCCCCCCEEEHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TTVGTEAQPLRVAIIGSGPSAFYAADHLLKQSDLVVEVDMFDRLPTPFGLVRGGVAPDH
CCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEEHHHCCCCCHHHHCCCCCCCH
QKIKTVTKAFNLVAKNPRFRFFGYVEYGKDLSHADLVEHYHQILYATGAQSDRHMGIPGE
HHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCH
DLTNSFPATAFVAWYNGHPDYRHLQFDLSQERVAVVGVGNVAIDVARILCLSHEELARTD
HHCCCCCCEEEEEEECCCCCCEEEEEECCCCCEEEEECCHHHHHHHHHHHHCHHHHHHHH
IADHALEALSKSNIKEVYLLGRRGPAQAAFTTPEVKELGELEEADVVAIPSEVALDDVSR
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHCCCCCCCEEECCCHHHHHHHHH
ADLEAGGDKAAQKKVELLQGYAQRAPEGKKRRLIFRFLVSPTEVLGDSDGRVAGLRLAKN
HHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHCCCCCCEEEEEEEHH
ELYASESGSIASRATGETEDLPVGLVFRSVGYRGSPLVDVPFNERWGTFLNQKGRIIDPT
HHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEECCCCCHHHHHHCCCCCEECCC
SQQPKIGEYTAGWIKRGPSGVIGTNKPDAVETVQCMLEDLATGQVLNPSHAERESIEKLV
CCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
QERQPNYVTFADWQHLDEIEVANGAATGRPRVKFTRIEDMLAALGKNVTA
HHCCCCEEEECCCCCCCCEEECCCCCCCCCCEEEHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 12071965; 12614197; 12102623 [H]