Click here to switch to the map view.

The map label for this gene is aprX [H]

Identifier: 159899534

GI number: 159899534

Start: 3806687

End: 3809194

Strand: Reverse

Name: aprX [H]

Synonym: Haur_3015

Alternate gene names: 159899534

Gene position: 3809194-3806687 (Counterclockwise)

Preceding gene: 159899537

Following gene: 159899533

Centisome position: 60.02

GC content: 50.8

Gene sequence:

>2508_bases
ATGCGATTATTTCATGGTCTTTTACTGATGAGCTTAGTCTTGCTAAGCTTCGGCGGTGCTGCTAGCAAACCACCTAGCAC
CACAATTCCACCCAAGTTGTATTTACAACGCGGCACGATCGATCTCAAAGTGGTTAATCAAGCCAACCAGGCTGATCCAT
TATTGCAGACAGTTGGGGGGTATGCGGTTATTCAATTTAGTGGGCCTGTGTTGCTCAAGCAGCGGCAAGCACTTGAAGCT
ACGGGGTTGAGCATTATTGAGTATCTCCCTGATTACGCCTATTTAGTTCGTGGCTCAGCTGCCCAACAAGCTGCTGCCAG
CCGAATTGATGGTTTTTATGCGCGTGGCGATTGGACGTTGGCCGATAAGTTTCATCCTGGGTTGTTGAAACTGATGCGCA
CTGGTGCGTATCAAGGTTTGGCGTTGCAGACGATTGGTTGGGATAACCAACTGACCACTGCTGAACAAGCAGTCAAAGCC
CAAGGCTTGAAGCTTGATGCCATTAGCACGATCGATCAACTGATTCAGTTGGCCCAAATTAATGAAGTGCGCTGGATCGA
AGTGGCGAGTACGCCGAAATTATTCGACCAATATGCGCGGCAAGTTCAGCAAGTTGAGCCTGTTTGGACTGATCGGCAGT
TGTATGGCCAAAATCAAATTGTGGCCTACACTGACACAGGTTTGGATACTGGCTCCTTGACAACCCTCAACAACGATTTT
ACCAATCGGATTCTTGCGACCCAAGTGCTCTCGGCTGGGGGGCATTGGGATGATAACCATGGCCATGGCACGCACGTTGC
TGGCTCGATTGCTGGTAACGGCGCACTTTCTGGCTCAAACCCAGCTACCCATACCTATACCAACTCGATGGCAGGGATTG
CGCCTGAGGCCAAGTTGGTTGTCCAAGCGTTTGAAGCAACTGCGACCGGCGATATTATTGGCTTGCCAACCGACCTCTAC
CCAATGTATCAGCAAGCCTATGATGCTGGAGCACGGATTCATAGCAATAGCTGGGGCGATGCAACCGGGCCAGTCAGTGA
TACAGAAGCTGCATTTGGGGGCTACCCCTATAATGCGCAACGCACCGACCAGTTTTTGTGGGAACACCCCGATTATACAA
TGTTGTTTGGGGCTGGTAATAGTGGGGTCGATGGAACCCCGAGCCAAGCAATCTTTTGTACTGGTGGTAATGGCGTTGTT
GACCCGGACTCGTTGCTCGCACCTGGGACTGCCAAGAATGTGATTACGGTTGGGGCTAGTGAAAGCCCGCGCCCAACGGG
TGGTTATACGGGTGTGCCTTGGCTTTTATTGAGTTTTTGCTTTGCCACCGCGCCAATTAACACGGATACTCTTTCTGATG
ATGCTAATGGGATAGCGGCATTCTCATCACGTGGGCCAACTGATGATGGCCGGATCAAGCCTGATTTGGTTGCCCCTGGC
ACGAATATTCTTTCAACTCGCTCATATGGCAGTGGGGCTGGTGCCTTATGGGGTGTTCATGAAACCAATGCCAATTACCT
TTATTCGGGTGGTACGTCGATGTCCACTCCGTTGGTTGCTGGTACGGTTGCCCTCATCCGCCAGTGGCTGGGTATCCAAG
GCTTGCCTAATCCTAGTGCCGCAGTCATCAAATCAATTGTTCTGAATACGACCGTTGATATTGCGCCCGGCCAATATGGT
ACTGGTGCAACTCAAGAAATTCCTTACAACCGCCCCAATAGTGTGGCTGGTTGGGGGCGTAGCAATTTGAGTTTTATTAC
CAAACCAGCGCCCTATCATTTGTGGGTTGCCGATCAGACGACTGGCTTGAATACAGGCCAGATGGTAAGCTATAACCATA
CTGCCAGCCAACCCCTAACCGTGTTGACCAATACCCAACCGCTGCGAGTTATGCTCAACTGGACTGATCCACCAGCTTCG
TTGGCAGCCACCCAACAATTGGTTAACGATCTTGATTTGGTGTTGATTGGGCCTGATGGTACGCGCTATTATGGCAATAA
TCAGAGCACTGGCGATCGCACGAATAATACCGAAGGTGTGATCATTAATAATCCCCAAATTGGTGCATATCAGATTGAAG
TTACTGCCCATAATGTACCTATTTCTAGCCAAGCCTATGGCTTGTCAGTCGCTGGCCCATTGCGTGAAGCTACTGGCGGC
GGTACGCCAACTCCAACCCCAACCGCTATAGCAACCGCAACAAATACGCCAACCAACACGGCGACCAATACACCAACCAA
CACGGCGACGAATACGCCAACCAACACGCCAACCAATACGCCAACCAATACACCAACCAATACACCAACCAACACGCCAA
CCAACACGGCGACCAATACACCAACCAACACGGCGACGAATACGCCAACCAACACGCCAACCAATACGCCAACCAACACG
GCGACCAATACACCAACCAACTCGCCAACCCCCACCAATCTGCCAACTGTGACCACGACAGCGGTTACAAACGAGTATGA
TGTTTGGATACCATGGGCGAGCAAATAA

Upstream 100 bases:

>100_bases
AAAAATTTTTTATAATTATATAATTGATTTTCCCTCAACGGTGTGCAATATTCATAGTTCTCTCGGGGCACACCCCTACC
ACAACCACTTGGAGGTCGGC

Downstream 100 bases:

>100_bases
ACGAAGCCTGACTAAAAACGCGATCAACTTAACTTGGTTGATCGCGTTTTTGTTTGCCCAAAAATCCCCCTTGACAGTCA
AACTTGGTTTAGTTATACTC

Product: peptidase S8/S53 subtilisin kexin sedolisin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 835; Mature: 835

Protein sequence:

>835_residues
MRLFHGLLLMSLVLLSFGGAASKPPSTTIPPKLYLQRGTIDLKVVNQANQADPLLQTVGGYAVIQFSGPVLLKQRQALEA
TGLSIIEYLPDYAYLVRGSAAQQAAASRIDGFYARGDWTLADKFHPGLLKLMRTGAYQGLALQTIGWDNQLTTAEQAVKA
QGLKLDAISTIDQLIQLAQINEVRWIEVASTPKLFDQYARQVQQVEPVWTDRQLYGQNQIVAYTDTGLDTGSLTTLNNDF
TNRILATQVLSAGGHWDDNHGHGTHVAGSIAGNGALSGSNPATHTYTNSMAGIAPEAKLVVQAFEATATGDIIGLPTDLY
PMYQQAYDAGARIHSNSWGDATGPVSDTEAAFGGYPYNAQRTDQFLWEHPDYTMLFGAGNSGVDGTPSQAIFCTGGNGVV
DPDSLLAPGTAKNVITVGASESPRPTGGYTGVPWLLLSFCFATAPINTDTLSDDANGIAAFSSRGPTDDGRIKPDLVAPG
TNILSTRSYGSGAGALWGVHETNANYLYSGGTSMSTPLVAGTVALIRQWLGIQGLPNPSAAVIKSIVLNTTVDIAPGQYG
TGATQEIPYNRPNSVAGWGRSNLSFITKPAPYHLWVADQTTGLNTGQMVSYNHTASQPLTVLTNTQPLRVMLNWTDPPAS
LAATQQLVNDLDLVLIGPDGTRYYGNNQSTGDRTNNTEGVIINNPQIGAYQIEVTAHNVPISSQAYGLSVAGPLREATGG
GTPTPTPTAIATATNTPTNTATNTPTNTATNTPTNTPTNTPTNTPTNTPTNTPTNTATNTPTNTATNTPTNTPTNTPTNT
ATNTPTNSPTPTNLPTVTTTAVTNEYDVWIPWASK

Sequences:

>Translated_835_residues
MRLFHGLLLMSLVLLSFGGAASKPPSTTIPPKLYLQRGTIDLKVVNQANQADPLLQTVGGYAVIQFSGPVLLKQRQALEA
TGLSIIEYLPDYAYLVRGSAAQQAAASRIDGFYARGDWTLADKFHPGLLKLMRTGAYQGLALQTIGWDNQLTTAEQAVKA
QGLKLDAISTIDQLIQLAQINEVRWIEVASTPKLFDQYARQVQQVEPVWTDRQLYGQNQIVAYTDTGLDTGSLTTLNNDF
TNRILATQVLSAGGHWDDNHGHGTHVAGSIAGNGALSGSNPATHTYTNSMAGIAPEAKLVVQAFEATATGDIIGLPTDLY
PMYQQAYDAGARIHSNSWGDATGPVSDTEAAFGGYPYNAQRTDQFLWEHPDYTMLFGAGNSGVDGTPSQAIFCTGGNGVV
DPDSLLAPGTAKNVITVGASESPRPTGGYTGVPWLLLSFCFATAPINTDTLSDDANGIAAFSSRGPTDDGRIKPDLVAPG
TNILSTRSYGSGAGALWGVHETNANYLYSGGTSMSTPLVAGTVALIRQWLGIQGLPNPSAAVIKSIVLNTTVDIAPGQYG
TGATQEIPYNRPNSVAGWGRSNLSFITKPAPYHLWVADQTTGLNTGQMVSYNHTASQPLTVLTNTQPLRVMLNWTDPPAS
LAATQQLVNDLDLVLIGPDGTRYYGNNQSTGDRTNNTEGVIINNPQIGAYQIEVTAHNVPISSQAYGLSVAGPLREATGG
GTPTPTPTAIATATNTPTNTATNTPTNTATNTPTNTPTNTPTNTPTNTPTNTPTNTATNTPTNTATNTPTNTPTNTPTNT
ATNTPTNSPTPTNLPTVTTTAVTNEYDVWIPWASK
>Mature_835_residues
MRLFHGLLLMSLVLLSFGGAASKPPSTTIPPKLYLQRGTIDLKVVNQANQADPLLQTVGGYAVIQFSGPVLLKQRQALEA
TGLSIIEYLPDYAYLVRGSAAQQAAASRIDGFYARGDWTLADKFHPGLLKLMRTGAYQGLALQTIGWDNQLTTAEQAVKA
QGLKLDAISTIDQLIQLAQINEVRWIEVASTPKLFDQYARQVQQVEPVWTDRQLYGQNQIVAYTDTGLDTGSLTTLNNDF
TNRILATQVLSAGGHWDDNHGHGTHVAGSIAGNGALSGSNPATHTYTNSMAGIAPEAKLVVQAFEATATGDIIGLPTDLY
PMYQQAYDAGARIHSNSWGDATGPVSDTEAAFGGYPYNAQRTDQFLWEHPDYTMLFGAGNSGVDGTPSQAIFCTGGNGVV
DPDSLLAPGTAKNVITVGASESPRPTGGYTGVPWLLLSFCFATAPINTDTLSDDANGIAAFSSRGPTDDGRIKPDLVAPG
TNILSTRSYGSGAGALWGVHETNANYLYSGGTSMSTPLVAGTVALIRQWLGIQGLPNPSAAVIKSIVLNTTVDIAPGQYG
TGATQEIPYNRPNSVAGWGRSNLSFITKPAPYHLWVADQTTGLNTGQMVSYNHTASQPLTVLTNTQPLRVMLNWTDPPAS
LAATQQLVNDLDLVLIGPDGTRYYGNNQSTGDRTNNTEGVIINNPQIGAYQIEVTAHNVPISSQAYGLSVAGPLREATGG
GTPTPTPTAIATATNTPTNTATNTPTNTATNTPTNTPTNTPTNTPTNTPTNTPTNTATNTPTNTATNTPTNTPTNTPTNT
ATNTPTNSPTPTNLPTVTTTAVTNEYDVWIPWASK

Specific function: Displays serine protease activity. Seems to have a broad substrate specificity [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Cytoplasm (Probable). Note=Is leaked to the culture medium during the late stationary phase owing to cell lysis [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 88137; Mature: 88137

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLFHGLLLMSLVLLSFGGAASKPPSTTIPPKLYLQRGTIDLKVVNQANQADPLLQTVGG
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHEEEECCCEEEEEECCCCCCCHHHHHCCC
YAVIQFSGPVLLKQRQALEATGLSIIEYLPDYAYLVRGSAAQQAAASRIDGFYARGDWTL
EEEEEECCCEEEHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHCCEEECCCEEE
ADKFHPGLLKLMRTGAYQGLALQTIGWDNQLTTAEQAVKAQGLKLDAISTIDQLIQLAQI
CCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEHHHHHHHHHHHHHHC
NEVRWIEVASTPKLFDQYARQVQQVEPVWTDRQLYGQNQIVAYTDTGLDTGSLTTLNNDF
CCEEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEEEECCCCCCCCEEEECCHH
TNRILATQVLSAGGHWDDNHGHGTHVAGSIAGNGALSGSNPATHTYTNSMAGIAPEAKLV
HHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCHHHH
VQAFEATATGDIIGLPTDLYPMYQQAYDAGARIHSNSWGDATGPVSDTEAAFGGYPYNAQ
HHHHHHCCCCCEEECCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCHHHCCCCCCCC
RTDQFLWEHPDYTMLFGAGNSGVDGTPSQAIFCTGGNGVVDPDSLLAPGTAKNVITVGAS
CCHHHHHCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCHHHHCCCCCCCCEEEECCC
ESPRPTGGYTGVPWLLLSFCFATAPINTDTLSDDANGIAAFSSRGPTDDGRIKPDLVAPG
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEECCC
TNILSTRSYGSGAGALWGVHETNANYLYSGGTSMSTPLVAGTVALIRQWLGIQGLPNPSA
CCEEEECCCCCCCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHH
AVIKSIVLNTTVDIAPGQYGTGATQEIPYNRPNSVAGWGRSNLSFITKPAPYHLWVADQT
HHHHHHHHHCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCC
TGLNTGQMVSYNHTASQPLTVLTNTQPLRVMLNWTDPPASLAATQQLVNDLDLVLIGPDG
CCCCCCCEEEECCCCCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEECCCC
TRYYGNNQSTGDRTNNTEGVIINNPQIGAYQIEVTAHNVPISSQAYGLSVAGPLREATGG
CEEECCCCCCCCCCCCCCEEEECCCCCCEEEEEEEEECCCCCCCCCCEEECCCHHHHCCC
GTPTPTPTAIATATNTPTNTATNTPTNTATNTPTNTPTNTPTNTPTNTPTNTPTNTATNT
CCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PTNTATNTPTNTPTNTPTNTATNTPTNSPTPTNLPTVTTTAVTNEYDVWIPWASK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEEEECCCC
>Mature Secondary Structure
MRLFHGLLLMSLVLLSFGGAASKPPSTTIPPKLYLQRGTIDLKVVNQANQADPLLQTVGG
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHEEEECCCEEEEEECCCCCCCHHHHHCCC
YAVIQFSGPVLLKQRQALEATGLSIIEYLPDYAYLVRGSAAQQAAASRIDGFYARGDWTL
EEEEEECCCEEEHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHCCEEECCCEEE
ADKFHPGLLKLMRTGAYQGLALQTIGWDNQLTTAEQAVKAQGLKLDAISTIDQLIQLAQI
CCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEHHHHHHHHHHHHHHC
NEVRWIEVASTPKLFDQYARQVQQVEPVWTDRQLYGQNQIVAYTDTGLDTGSLTTLNNDF
CCEEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEEEECCCCCCCCEEEECCHH
TNRILATQVLSAGGHWDDNHGHGTHVAGSIAGNGALSGSNPATHTYTNSMAGIAPEAKLV
HHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCHHHH
VQAFEATATGDIIGLPTDLYPMYQQAYDAGARIHSNSWGDATGPVSDTEAAFGGYPYNAQ
HHHHHHCCCCCEEECCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCHHHCCCCCCCC
RTDQFLWEHPDYTMLFGAGNSGVDGTPSQAIFCTGGNGVVDPDSLLAPGTAKNVITVGAS
CCHHHHHCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCHHHHCCCCCCCCEEEECCC
ESPRPTGGYTGVPWLLLSFCFATAPINTDTLSDDANGIAAFSSRGPTDDGRIKPDLVAPG
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEECCC
TNILSTRSYGSGAGALWGVHETNANYLYSGGTSMSTPLVAGTVALIRQWLGIQGLPNPSA
CCEEEECCCCCCCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHH
AVIKSIVLNTTVDIAPGQYGTGATQEIPYNRPNSVAGWGRSNLSFITKPAPYHLWVADQT
HHHHHHHHHCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCC
TGLNTGQMVSYNHTASQPLTVLTNTQPLRVMLNWTDPPASLAATQQLVNDLDLVLIGPDG
CCCCCCCEEEECCCCCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEECCCC
TRYYGNNQSTGDRTNNTEGVIINNPQIGAYQIEVTAHNVPISSQAYGLSVAGPLREATGG
CEEECCCCCCCCCCCCCCEEEECCCCCCEEEEEEEEECCCCCCCCCCEEECCCHHHHCCC
GTPTPTPTAIATATNTPTNTATNTPTNTATNTPTNTPTNTPTNTPTNTPTNTPTNTATNT
CCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PTNTATNTPTNTPTNTPTNTATNTPTNSPTPTNLPTVTTTAVTNEYDVWIPWASK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]