Click here to switch to the map view.

The map label for this gene is pld [H]

Identifier: 159899477

GI number: 159899477

Start: 3732430

End: 3733644

Strand: Reverse

Name: pld [H]

Synonym: Haur_2958

Alternate gene names: 159899477

Gene position: 3733644-3732430 (Counterclockwise)

Preceding gene: 159899478

Following gene: 159899476

Centisome position: 58.83

GC content: 45.51

Gene sequence:

>1215_bases
ATGGCGCGTAGCACATCGACCACGAAGCTCAAACCTTGGCAAATTGTCGTGATTCTGGTGATTGCTGGGTTGGTTTATGC
CTATCAGGCGGGCTATTTCAATCGTTGGCTTGGCAGTACTAGCCTTGAACCAACCAGCGTGGCTGGGCCAACGACACCCA
CAAACCCGCCAACAATGGCCGATCCCAATAATGTGCTCGCGGCGCTTGATCCAGATAAAGCCTATGTTGCCGAAGGTGCA
TGGTATCAGGTATTTTTTACCCGCCCAAGCTACCCTGAAAAAGCAGCAGGCCGGAAAGGTGGGGTTGATGCGGCGATGAT
TGCCGATATTGATGCTGCTAAAAGCACGATTTATATTGCATCGTTCGATTTTGATTTAGAATTGATGACCGATGCCTTGA
TTCGCGCCAAAAAGCGTAAAGTCAAAGTTCAGCTCGTGGTTGATGATGAAAATTTGGCTTCACCGGAAGTTGCCGAAACG
ACAGGTCGTTTGGAAGCAGCTAAAATCCCAATTACGTGGGATGAGCGTTCAGCGTTTATGCACAACAAAATCGTGGTCAT
TGACGATACAATTGTTTGGACTGGCTCGATGAATTTGGTTGTAAACGACGTTTATCGTAACAACAATAATATGATTCGTT
CCACCGTGCCTGAGTTGGTCGCTAATTATCGCCAGCGTTTCTTGGATTTGTTCGCTGGCAAGCTGGGTAGTAAAGCTCCC
AAAAATACGCCCAACCCAGTAATTAAATTGGCTGGTGGGGTGCAGATCGAAACCTATTTTTCGCCAGTCGATAAGCCGCG
CTCGAAAATTGTCAATTATATTAAAAAGGCCAAACAATCGGTCAATGTACTGGCATTTTCGTTTACCGACGATGATACCG
CCCAAGCCTTAATCGATCGCCATGAAGCTGGCTTAGAAATTCAAGTTGTGATGGAAGCTCGCAACGCCGATGGCACTGGC
TCGGAGTTTGGCATTTTGGAAGATGCCGGAATCCCGATTTTACGTGATGCGAATTGTTATATTTTACATAATAAAACGAT
GATTATCGACGAAAAAATCGTGATTACTGGCTCGTATAATTTTACTGCGGCAGCTGAAAATAATAACGATGAAAATTTAT
TGATTATTACTGATCCCGATTTGGCACGCCATTATTTGGCTGAATTTGATCGGCTGTATGCCCAAGCCAAAAATCCTGCT
GGTTGTGGCCGTTAG

Upstream 100 bases:

>100_bases
TGAGGGATGAAATTAAATAATTCGTGGAATTCGTGGAATTCGTGGCTAAAAATCTGATCCCTAGCCCCTGCCCCCTACCC
ACTATCGAAAGGCTGGAATA

Downstream 100 bases:

>100_bases
CGAGTATTCATGCGGATTTTACACGTTATTCAGCGCTATTACCCGTATATCGGCGGCTCAGAGCAGGTTTGCCAAGTGAT
TGCTGAACGGTTGGCAGCCG

Product: phospholipase D/transphosphatidylase

Products: NA

Alternate protein names: PLD; Choline phosphatase [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MARSTSTTKLKPWQIVVILVIAGLVYAYQAGYFNRWLGSTSLEPTSVAGPTTPTNPPTMADPNNVLAALDPDKAYVAEGA
WYQVFFTRPSYPEKAAGRKGGVDAAMIADIDAAKSTIYIASFDFDLELMTDALIRAKKRKVKVQLVVDDENLASPEVAET
TGRLEAAKIPITWDERSAFMHNKIVVIDDTIVWTGSMNLVVNDVYRNNNNMIRSTVPELVANYRQRFLDLFAGKLGSKAP
KNTPNPVIKLAGGVQIETYFSPVDKPRSKIVNYIKKAKQSVNVLAFSFTDDDTAQALIDRHEAGLEIQVVMEARNADGTG
SEFGILEDAGIPILRDANCYILHNKTMIIDEKIVITGSYNFTAAAENNNDENLLIITDPDLARHYLAEFDRLYAQAKNPA
GCGR

Sequences:

>Translated_404_residues
MARSTSTTKLKPWQIVVILVIAGLVYAYQAGYFNRWLGSTSLEPTSVAGPTTPTNPPTMADPNNVLAALDPDKAYVAEGA
WYQVFFTRPSYPEKAAGRKGGVDAAMIADIDAAKSTIYIASFDFDLELMTDALIRAKKRKVKVQLVVDDENLASPEVAET
TGRLEAAKIPITWDERSAFMHNKIVVIDDTIVWTGSMNLVVNDVYRNNNNMIRSTVPELVANYRQRFLDLFAGKLGSKAP
KNTPNPVIKLAGGVQIETYFSPVDKPRSKIVNYIKKAKQSVNVLAFSFTDDDTAQALIDRHEAGLEIQVVMEARNADGTG
SEFGILEDAGIPILRDANCYILHNKTMIIDEKIVITGSYNFTAAAENNNDENLLIITDPDLARHYLAEFDRLYAQAKNPA
GCGR
>Mature_403_residues
ARSTSTTKLKPWQIVVILVIAGLVYAYQAGYFNRWLGSTSLEPTSVAGPTTPTNPPTMADPNNVLAALDPDKAYVAEGAW
YQVFFTRPSYPEKAAGRKGGVDAAMIADIDAAKSTIYIASFDFDLELMTDALIRAKKRKVKVQLVVDDENLASPEVAETT
GRLEAAKIPITWDERSAFMHNKIVVIDDTIVWTGSMNLVVNDVYRNNNNMIRSTVPELVANYRQRFLDLFAGKLGSKAPK
NTPNPVIKLAGGVQIETYFSPVDKPRSKIVNYIKKAKQSVNVLAFSFTDDDTAQALIDRHEAGLEIQVVMEARNADGTGS
EFGILEDAGIPILRDANCYILHNKTMIIDEKIVITGSYNFTAAAENNNDENLLIITDPDLARHYLAEFDRLYAQAKNPAG
CGR

Specific function: Could be a virulence factor [H]

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PLD phosphodiesterase domain [H]

Homologues:

Organism=Homo sapiens, GI270265812, Length=114, Percent_Identity=34.2105263157895, Blast_Score=83, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001736 [H]

Pfam domain/function: NA

EC number: =3.1.4.4 [H]

Molecular weight: Translated: 44487; Mature: 44356

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARSTSTTKLKPWQIVVILVIAGLVYAYQAGYFNRWLGSTSLEPTSVAGPTTPTNPPTMA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCC
DPNNVLAALDPDKAYVAEGAWYQVFFTRPSYPEKAAGRKGGVDAAMIADIDAAKSTIYIA
CCCCEEEEECCCHHEEECCCEEEEEEECCCCCHHHCCCCCCCCEEEEEECCCCCCEEEEE
SFDFDLELMTDALIRAKKRKVKVQLVVDDENLASPEVAETTGRLEAAKIPITWDERSAFM
EECCCHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHCCCEEEEEECEEECCCCHHH
HNKIVVIDDTIVWTGSMNLVVNDVYRNNNNMIRSTVPELVANYRQRFLDLFAGKLGSKAP
HCEEEEEECEEEEECCCEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KNTPNPVIKLAGGVQIETYFSPVDKPRSKIVNYIKKAKQSVNVLAFSFTDDDTAQALIDR
CCCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHH
HEAGLEIQVVMEARNADGTGSEFGILEDAGIPILRDANCYILHNKTMIIDEKIVITGSYN
HHCCCEEEEEEEECCCCCCCCCCCEEECCCCCEEECCCEEEEECCEEEEEEEEEEEECCC
FTAAAENNNDENLLIITDPDLARHYLAEFDRLYAQAKNPAGCGR
EEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ARSTSTTKLKPWQIVVILVIAGLVYAYQAGYFNRWLGSTSLEPTSVAGPTTPTNPPTMA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCC
DPNNVLAALDPDKAYVAEGAWYQVFFTRPSYPEKAAGRKGGVDAAMIADIDAAKSTIYIA
CCCCEEEEECCCHHEEECCCEEEEEEECCCCCHHHCCCCCCCCEEEEEECCCCCCEEEEE
SFDFDLELMTDALIRAKKRKVKVQLVVDDENLASPEVAETTGRLEAAKIPITWDERSAFM
EECCCHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHCCCEEEEEECEEECCCCHHH
HNKIVVIDDTIVWTGSMNLVVNDVYRNNNNMIRSTVPELVANYRQRFLDLFAGKLGSKAP
HCEEEEEECEEEEECCCEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KNTPNPVIKLAGGVQIETYFSPVDKPRSKIVNYIKKAKQSVNVLAFSFTDDDTAQALIDR
CCCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHH
HEAGLEIQVVMEARNADGTGSEFGILEDAGIPILRDANCYILHNKTMIIDEKIVITGSYN
HHCCCEEEEEEEECCCCCCCCCCCEEECCCCCEEECCCEEEEECCEEEEEEEEEEEECCC
FTAAAENNNDENLLIITDPDLARHYLAEFDRLYAQAKNPAGCGR
EEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA